Pre-Clinical Studying of Antitumor Ramon Preparation: Specific Activity

In article the data of pre-clinical researches of Ramon
preparation is described. Antitumor activity of Ramon has been
studied on 19 strains of transplantated tumors of different
hystogenesis.

• Raissa A. Muzychkina
• Irina M. Korulkina
• Dmitriy Yu. Korulkin

• Cancer
• antitumor activity
• pre-clinical testing
• anthraquinones
• phytopreparation
• Ramon.

<p>[1] R.A.Muzychkina, Natural Anthraquinones. Biological Properties and
Physicochemical Characteristics, Moscow: Phasis, 1998.
[2] S.K.Gupta, Drug Screening Methods, Kent: Anshan Publishers, 2009.
[3] V.E.Steele, R.A.Lubet, R.C.Moon, &ldquo;Preclinical animal models for the
development of cancer chemoprevention drugs,&rdquo; Cancer
Chemoprevention, vol. 2, pp. 568-571, 2005.
[4] A.A.AlFattah Amara, &ldquo;Methods other than Experimental Animals
for Screening Antitumor Compounds,&rdquo; Am. J. Cancer Sci., vol. 2,
no. 1, pp. 1-27, 2013.
[5] H.G.Vogel, J.Maas, A.Gebauer, Drug Discovery and Evaluation:
Methods in Clinical Pharmacology, Berlin: Springer, 2011.
[6] J.Kolman, P.Meng, G.Scott,Good clinical practice: standard operating
procedures for clinical researchers, New-York:J. Wiley &amp; Sons, 1998.</p>