Beam Orientation Optimization Using Ant Colony Optimization in Intensity Modulated Radiation Therapy

In intensity modulated radiation therapy (IMRT) treatment planning, beam angles are usually preselected on the basis of experience and intuition. Therefore, getting an appropriate beam configuration needs a very long time. Based on the present situation, the paper puts forward beam orientation optimization using ant colony optimization (ACO). We use ant colony optimization to select the beam configurations, after getting the beam configuration using Conjugate Gradient (CG) algorithm to optimize the intensity profiles. Combining with the information of the effect of pencil beam, we can get the global optimal solution accelerating. In order to verify the feasibility of the presented method, a simulated and clinical case was tested, compared with dose-volume histogram and isodose line between target area and organ at risk. The results showed that the effect was improved after optimizing beam configurations. The optimization approach could make treatment planning meet clinical requirements more efficiently, so it had extensive application perspective.

Authors:

• Xi Pei
• Ruifen Cao
• Hui Liu
• Chufeng Jin
• Mengyun Cheng
• Huaqing Zheng
• Yican Wu
• FDS Team

Keywords:

• intensity modulated radiation therapy
• ant colonyoptimization
• Conjugate Gradient algorithm

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