pH-Responsiveness Properties of a Biodigradable Hydrogels Based on Carrageenan-g-poly(NaAA-co-NIPAM)
A novel thermo-sensitive superabsorbent hydrogel
with salt- and pH-responsiveness properties was obtained by grafting
of mixtures of acrylic acid (AA) and N-isopropylacrylamide
(NIPAM) monomers onto kappa-carrageenan, kC, using ammonium
persulfate (APS) as a free radical initiator in the presence of
methylene bisacrylamide (MBA) as a crosslinker. Infrared
spectroscopy was carried out to confirm the chemical structure of the
hydrogel. Moreover, morphology of the samples was examined by
scanning electron microscopy (SEM). The effect of MBA
concentration and AA/NIPAM weight ratio on the water absorbency
capacity has been investigated. The swelling variations of hydrogels
were explained according to swelling theory based on the hydrogel
chemical structure. The hydrogels exhibited salt-sensitivity and
cation exchange properties. The temperature- and pH-reversibility
properties of the hydrogels make the intelligent polymers as good
candidates for considering as potential carriers for bioactive agents,
e.g. drugs.
[1] Hermans, J. J.; In Flow Properties of Disperse Systems, Wiley
Interscience, New York, 1953.
[2] Salamone, J. C., Ed.; CRC Press: Boca Raton, FL, 1996; Vol. 5, p 3282.
[1] Hermans, J. J.; In Flow Properties of Disperse Systems, Wiley
Interscience, New York, 1953.
[2] Salamone, J. C., Ed.; CRC Press: Boca Raton, FL, 1996; Vol. 5, p 3282.
@article{"International Journal of Chemical, Materials and Biomolecular Sciences:56057", author = "Mohammad Sadeghi and Behrouz Heidari and Korush Montazeri", title = "pH-Responsiveness Properties of a Biodigradable Hydrogels Based on Carrageenan-g-poly(NaAA-co-NIPAM)", abstract = "A novel thermo-sensitive superabsorbent hydrogel
with salt- and pH-responsiveness properties was obtained by grafting
of mixtures of acrylic acid (AA) and N-isopropylacrylamide
(NIPAM) monomers onto kappa-carrageenan, kC, using ammonium
persulfate (APS) as a free radical initiator in the presence of
methylene bisacrylamide (MBA) as a crosslinker. Infrared
spectroscopy was carried out to confirm the chemical structure of the
hydrogel. Moreover, morphology of the samples was examined by
scanning electron microscopy (SEM). The effect of MBA
concentration and AA/NIPAM weight ratio on the water absorbency
capacity has been investigated. The swelling variations of hydrogels
were explained according to swelling theory based on the hydrogel
chemical structure. The hydrogels exhibited salt-sensitivity and
cation exchange properties. The temperature- and pH-reversibility
properties of the hydrogels make the intelligent polymers as good
candidates for considering as potential carriers for bioactive agents,
e.g. drugs.", keywords = "superabsorbent, carrageenan, acrylic acid, Nisopropylacrylamide,hydrogel, swelling", volume = "5", number = "4", pages = "332-4", }