Abstract: This paper presents an approach for early breast
cancer diagnostic by employing combination of artificial neural
networks (ANN) and multiwaveletpacket based subband image
decomposition. The microcalcifications correspond to high-frequency
components of the image spectrum, detection of microcalcifications
is achieved by decomposing the mammograms into different
frequency subbands,, reconstructing the mammograms from the
subbands containing only high frequencies. For this approach we
employed different types of multiwaveletpacket. We used the result
as an input of neural network for classification. The proposed
methodology is tested using the Nijmegen and the Mammographic
Image Analysis Society (MIAS) mammographic databases and
images collected from local hospitals. Results are presented as the
receiver operating characteristic (ROC) performance and are
quantified by the area under the ROC curve.
Abstract: Deep Brain Stimulation or DBS is the second solution
for Parkinson's Disease. Its three parameters are: frequency, pulse
width and voltage. They must be optimized to achieve successful
treatment. Nowadays it is done clinically by neurologists and there is
not certain numerical method to detect them. The aim of this research
is to introduce simulation and modeling of Parkinson's Disease
treatment as a computational procedure to select optimum voltage.
We recorded finger tremor signals of some Parkinsonian patients
under DBS treatment at constant frequency and pulse width but
variable voltages; then, we adapted a new model to fit these data. The
optimum voltages obtained by data fitting results were the same as
neurologists- commented voltages, which means modeling can be
used as an engineering method to select optimum stimulation
voltages.
Abstract: This paper systematically investigates the timedependent
health outcomes for office staff during computer work
using the developed mathematical model. The model describes timedependent
health outcomes in multiple body regions associated with
computer usage. The association is explicitly presented with a doseresponse
relationship which is parametrized by body region
parameters. Using the developed model we perform extensive
investigations of the health outcomes statically and dynamically. We
compare the risk body regions and provide various severity rankings
of the discomfort rate changes with respect to computer-related
workload dynamically for the study population. Application of the
developed model reveals a wide range of findings. Such broad
spectrum of investigations in a single report literature is lacking.
Based upon the model analysis, it is discovered that the highest
average severity level of the discomfort exists in neck, shoulder, eyes,
shoulder joint/upper arm, upper back, low back and head etc. The
biggest weekly changes of discomfort rates are in eyes, neck, head,
shoulder, shoulder joint/upper arm and upper back etc. The fastest
discomfort rate is found in neck, followed by shoulder, eyes, head,
shoulder joint/upper arm and upper back etc. Most of our findings are
consistent with the literature, which demonstrates that the developed
model and results are applicable and valuable and can be utilized to
assess correlation between the amount of computer-related workload
and health risk.
Abstract: The aim of this studywas toinvestigate the effect
ofrunning classification (sprint, middle, and long distance)and two
distances on blood lactate (BLa), heart rate (HR), and rating of
perceived exertion (RPE) Borg scale ratings in collegiate athletes. On
different days, runners (n = 15) ran 400m and 1600m at a five min
mile pace, followed by a two min 6mph jog, and a two min 3mph
walk as part of the cool down. BLa, HR, and RPE were taken at
baseline, post-run, plus 2 and 4 min recovery times. The middle and
long distance runners exhibited lower BLa concentrations than sprint
runners after two min of recovery post 400 m runs, immediately after,
and two and four min recovery periods post 1600 m runs. When
compared to sprint runners, distance runners may have exhibited the
ability to clear BLa more quickly, particularly after running 1600 m.
Abstract: Functional gastrointestinal disorders affect millions of people spread all age regardless of race and sex. There are, however, rare diagnostic methods for the functional gastrointestinal disorders because functional disorders show no evidence of organic and physical causes. Our research group identified recently that the gastrointestinal tract well in the patients with the functional gastrointestinal disorders becomes more rigid than healthy people when palpating the abdominal regions overlaying the gastrointestinal tract. Aim of this study is, therefore, to develop a diagnostic system for the functional gastrointestinal disorders based on ultrasound technique, which can quantify the characteristic above related to the rigidity of the gastrointestinal tract well. Ultrasound system was designed. The system consisted of transmitter, ultrasonic transducer, receiver, TGC, and CPLD, and verified via a phantom test. For the phantom test, ten soft-tissue specimens were harvested from porcine. Five of them were then treated chemically to mimic a rigid condition of gastrointestinal tract well, which was induced by functional gastrointestinal disorders. Additionally, the specimens were tested mechanically to identify if the mimic was reasonable. The customized ultrasound system was finally verified through application to human subjects with/without functional gastrointestinal disorders (Normal and Patient Groups). It was identified from the mechanical test that the chemically treated specimens were more rigid than normal specimen. This finding was favorably compared with the result obtained from the phantom test. The phantom test also showed that ultrasound system well described the specimen geometric characteristics and detected an alteration in the specimens. The maximum amplitude of the ultrasonic reflective signal in the rigid specimens (0.2±0.1Vp-p) at the interface between the fat and muscle layers was explicitly higher than that in the normal specimens (0.1±0.0Vp-p). Clinical tests using our customized ultrasound system for human subject showed that the maximum amplitudes of the ultrasonic reflective signals near to the gastrointestinal tract well for the patient group (2.6±0.3Vp-p) were generally higher than those in normal group (0.1±0.2Vp-p). Here, maximum reflective signals was appeared at 20mm depth approximately from abdominal skin for all human subjects, corresponding to the location of the boundary layer close to gastrointestinal tract well. These results suggest that newly designed diagnostic system based on ultrasound technique may diagnose enough the functional gastrointestinal disorders.
Abstract: The present study was conducted to observe the effect
of Plantago psyllium on blood glucose and cholesterol levels in
normal and alloxan induced diabetic rats. To investigate the effect of
Plantago psyllium 40 rats were included in this study divided into
four groups of ten rats in each group. One group A was normal,
second group B was diabetic, third group C was non diabetic and
hypercholesterolemic and fourth group D was diabetic and
hypercholesterolemic. Two groups B and D were made diabetic by
intraperitonial injection of alloxan dissolved in 1mL distilled water at
a dose of 125mg/Kg of body weight. Two groups C and D were
made hypercholesterolemic by oral administration of powder
cholesterol (1g/Kg of body weight). The blood samples from all the
rats were collected from coccygial vein on 1st day, then on 21st and
42nd day respectively. All the samples were analyzed for blood
glucose and cholesterol level by using enzymatic kits. The blood
glucose and cholesterol levels of treated groups of rats showed
significant reduction after 7 weeks of treatment with Plantago
psyllium. By statistical analysis of results it was found that Plantago
psyllium has anti-diabetic and hypocholesterolemic activity in
diabetic and hypercholesterolemic albino rats.
Abstract: Industrial robots become useless without end-effectors
that for many instances are in the form of friction grippers.
Commonly friction grippers apply frictional forces to different
objects on the basis of programmers- experiences. This puts a
limitation on the effectiveness of gripping force that may result in
damaging the object. This paper describes various stages of design
and development of a low cost sensor-based robotic gripper that
would facilitate the task of applying right gripping forces to different
objects. The gripper is also equipped with range sensors in order to
avoid collisions of the gripper with objects. It is a fully functional
automated pick and place gripper which can be used in many
industrial applications. Yet it can also be altered or further developed
in order to suit a larger number of industrial activities. The current
design of gripper could lead to designing completely automated robot
grippers able to improve the efficiency and productivity of industrial
robots.
Abstract: The method described in this paper deals with the problems of T-wave detection in an ECG. Determining the position of a T-wave is complicated due to the low amplitude, the ambiguous and changing form of the complex. A wavelet transform approach handles these complications therefore a method based on this concept was developed. In this way we developed a detection method that is able to detect T-waves with a sensitivity of 93% and a correct-detection ratio of 93% even with a serious amount of baseline drift and noise.
Abstract: Optical Coherence Tomography (OCT) combined
with the Confocal Microscopy, as a noninvasive method, permits the
determinations of materials defects in the ceramic layers depth. For
this study 256 anterior and posterior metal and integral ceramic fixed
partial dentures were used, made with Empress (Ivoclar), Wollceram
and CAD/CAM (Wieland) technology. For each investigate area 350
slices were obtain and a 3D reconstruction was perform from each
stuck. The Optical Coherent Tomography, as a noninvasive method,
can be used as a control technique in integral ceramic technology,
before placing those fixed partial dentures in the oral cavity. The
purpose of this study is to evaluate the capability of En face Optical
Coherence Tomography (OCT) combined with a fluorescent method
in detection and analysis of possible material defects in metalceramic
and integral ceramic fixed partial dentures. As a conclusion,
it is important to have a non invasive method to investigate fixed
partial prostheses before their insertion in the oral cavity in order to
satisfy the high stress requirements and the esthetic function.
Abstract: Heart disease (HD) is a major cause of morbidity and mortality in the modern society. Medical diagnosis is an important but complicated task that should be performed accurately and efficiently and its automation would be very useful. All doctors are unfortunately not equally skilled in every sub specialty and they are in many places a scarce resource. A system for automated medical diagnosis would enhance medical care and reduce costs. In this paper, a new approach based on coactive neuro-fuzzy inference system (CANFIS) was presented for prediction of heart disease. The proposed CANFIS model combined the neural network adaptive capabilities and the fuzzy logic qualitative approach which is then integrated with genetic algorithm to diagnose the presence of the disease. The performances of the CANFIS model were evaluated in terms of training performances and classification accuracies and the results showed that the proposed CANFIS model has great potential in predicting the heart disease.
Abstract: Surgical site infections (SSIs) are the most common
nosocomial infection in surgical patients resulting in significant
increases in postoperative morbidity and mortality. The commonly
causative bacteria developed resistance to virtually all antibiotics
available. The aim of this study was to isolation and identification the
most common bacteria that cause SSIs in Medical Research Institute,
and to compare their sensitivity to selected group of antibiotics and
natural products (garlic, oregano, olive, and Nigella sativa oils). The
isolated pathogens collected from infected surgical wounds were
identified, and their sensitivities to the antibiotics commonly
available for clinical use, and also to the different concentrations of
the used natural products were investigated. The results indicate to
the potential therapeutic effect of the tested natural products in
treatment of surgical wound infections.
Abstract: Vitamin A deficiency is a public health problem in
Zimbabwe. Addressing vitamin A deficiency has the potential of
enhancing resistance to disease and reducing mortality especially in
children less than 5 years. We implemented and adapted vitamin A
outreach supplementation strategy within the National Immunization
Days and Extended Programme of Immunization in a rural district in
Zimbabwe. Despite usual operational challenges faced this approach
enabled the district to increase delivery of supplementation coverage.
This paper describes the outreach strategy that was implemented in
the remote rural district. The strategy covered 63 outreach sites with
2 sites being covered per day and visited once per month for the
whole year. Coverage reached 71% in an area of previous coverage
rates of around less than 50%. We recommend further exploration of
this strategy by others working in similar circumstances. This
strategy can be a potential way for use by Scaling-Up-Nutrition
member states.
Abstract: Inflammatory bowel disease (IBD) is a chronic
relapsing-remitting condition that afflicts millions of people
throughout the world and impairs their daily functions and quality of
life. Treatment of IBD depends largely on 5-aminosalicylic acid (5-
ASA) and corticosteroids. The present study aimed to clarify the
effects of 5-aminosalicylic acid, budesonide and currcumin on 90
male albino rats against trinitrobenzene sulfonic acid (TNB) induced
colitis. TNB was injected intrarectally to 50 rats. The other 40 rats
served as control groups. Both 5-ASA (in a dose of 120 mg/kg) and
budesonide (in a dose of 0.1 mg/kg) were administered daily for one
week whereas currcumin was injected intraperitonially (in a dose of
30 mg/kg daily) for 14 days after injection of either TNB in the
colitis rats (group B) or saline in control groups (group A). The study
included estimation of macroscopic score index, histological
examination of H&E stained sections of the colonic tissue,
biochemical estimation of myeloperoxidase (MPO), nitric oxide
(NO), and caspase-3 levels, in addition to studying the effect of tested
drugs on colonic motility. It was found that budesonide and curcumin
improved mucosal healing, reduced both NO production and caspase-
3 level. They had the best impact on the disturbed colonic motility in
TNBS-model of colitis.
Abstract: This study was conducted to examine the effects of ketum extract on development of Chrysomya rufifacies and to analyze the presence of mitragynine in the larvae samples. 110 newly emerged first instar larvae of C. rufifacies were introduced on ketum extract-mixed cow liver at doses of 0, 20, 40 and 60g. Blowfly development rate was determined with 12 hour intervals and
mitragynine in larvae was extracted and quantitated. C. rufifacies in control group took about 192 hours to complete their development from first instar larvae to adult blowfly; meanwhile blowfly form from the highest dose of ketum was 264 hours. Mitragynine was detected in all groups of treatment, except for control. In conclusion, the presence of mitragynine in C. rufifacies is affected in delaying development rates of the blowfly for up to 62 hours or 3 days. Chemical analysis of mitragynine from larvae samples showed that this alkaloid present in all specimens analyzed.
Abstract: TTV is an unenveloped circular single-stranded DNA
virus with a diameter of 30-32 nm that first was described in 1997 in
Japan. TTV was detected in various populations without proven
pathology, including blood donors and in patients with chronic HBV
and HCV hepatitis. The aim of this study was to determine the
prevalence of TTV DNA in Iranian patients with chronic hepatitis B
and C. Viral TTV-DNA was studied in 442 samples (202 with HBV,
138 with HCV and 102 controls) collected from west south of Iran.
All extracted serum DNA was amplified by TTV ORF1 gene specific
primers using the semi nested PCR technique. TTV DNA was
detected in the serum of 8.9% and 10.8% patients with chronic
hepatitis B and C, respectively. Prevalence of TTV-DNA in the serum
of 102 controls was 2.9%. Results showed significant relation of TTV
with HBV and HCV in patients by using T test examination (P
Abstract: Anxiety is a common disorder that attacks many people in society and often accompanied by physiological sensations such as tachycardia, chest pain, shortness of breath, insensitivity and etc. The purpose of this study is to characterize the putative anxiolytic-like effects of DEV (dichloromethane extracts of valerian) using the elevated plus maze (EPM) in rats. DEV was dissolved in DMSO and orally administered at different doses to adult male wistar rats, 0.5, 1.5 and 3 hours before behavioral evaluation in an EPM respectively. Control rats were treated with an equal volume of DMSO. Single treatment of DEV (at 0.1,0.2. 0.3, and 0.4 g/kg) significantly increased time-spent and arm entries into open arms of EPM versus control groups (p
Abstract: Atherosclerosis is the condition in which an artery
wall thickens as the result of a build-up of fatty materials such as
cholesterol. It is a syndrome affecting arterial blood vessels, a
chronic inflammatory response in the walls of arteries, in large part
due to the accumulation of macrophage white blood cells and
promoted by low density (especially small particle) lipoproteins
(plasma proteins that carry cholesterol and triglycerides) without
adequate removal of fats and cholesterol from the macrophages by
functional high density lipoproteins (HDL). It is commonly referred
to as a hardening or furring of the arteries. It is caused by the
formation of multiple plaques within the arteries.
Abstract: Purpose of this work is the development of an
automatic classification system which could be useful for radiologists
in the investigation of breast cancer. The software has been designed
in the framework of the MAGIC-5 collaboration.
In the automatic classification system the suspicious regions with
high probability to include a lesion are extracted from the image as
regions of interest (ROIs). Each ROI is characterized by some
features based on morphological lesion differences.
Some classifiers as a Feed Forward Neural Network, a K-Nearest
Neighbours and a Support Vector Machine are used to distinguish the
pathological records from the healthy ones.
The results obtained in terms of sensitivity (percentage of
pathological ROIs correctly classified) and specificity (percentage of
non-pathological ROIs correctly classified) will be presented through
the Receive Operating Characteristic curve (ROC). In particular the
best performances are 88% ± 1 of area under ROC curve obtained
with the Feed Forward Neural Network.
Abstract: Bay leaves have been shown to improve insulin
function in vitro but the effects on people have not been determined.
The objective of this study was to determine if bay leaves may be
important in the prevention and/or alleviation of type 1 diabetes.
Methods: Fifty five people with type 1 diabetes were divided into
two groups, 45 given capsules containing 3 g of bay leaves per day
for 30 days and 10 given a placebo capsules. Results All the patients
consumed bay leaves shows reduced serum glucose with significant
decreases 27% after 30 d. Total cholesterol decreased, 21 %, after 30
days with larger decreases in low density lipoprotein (LDL) 24%.
High density lipoprotein (HDL) increased 20% and Triglycerides
also decreased 26%. There were no significant changes in the
placebo group. Conclusion, this study demonstrates that consumption
of bay leaves, 3 g/d for 30 days, decreases risk factors for diabetes
and cardiovascular diseases and suggests that bay leaves may be
beneficial for people with type 1 diabetes.
Abstract: The major source of allergy in home is the house dust
mite (Dematophagoides farina, Dermatophagoides pteronyssinus)
causing allergic symptom include atopic dermatitis, asthma, perennial
rhinitis and even infant death syndrome.
Control of this mite species is dependent on the use of chemical
methods such as fumigation treatments with methylene bromide,
spraying with organophosphates such as pirimiphos-methyl, or
treatments with repellents such as DEET and benzyl benzoate.
Although effective, their repeated use for decades has sometimes
resulted in development of resistance and fostered environmental and
human health concerns. Both decomposing animal parts and the
protein that surrounds mite fecal pellets cause mite allergy. So it is
more effective to repel than to kill them because allergen is not living
house dust mite but dead body or fecal particles of house dust mite.
It is important to find out natural repellent material against house
dust mite to control them and reduce the allergic reactions. Plants may
be an alternative source for dust mite control because they contain a
range of bioactive chemicals.
The research objectives of this paper were to verify the acaricidal
and repellent effects of cinnamon essential oil and to find out it-s most
effective concentrations. We could find that cinnamon bark essential
oil was very effective material to control the house dust mite.
Furthermore, it could reduce chemical resistance and danger for
human health.