Abstract: Candida spp. are common and aggressive pathogens.
Because of the growing resistance of Candida spp. to current
antifungals, novel targets, found in Candida spp. but not in humans
or other flora, have to be identified. The alternative oxidase (AOX)
is one such possibility. This enzyme is insensitive to cyanide, but is
sensitive to compounds such as salicylhydroxamic acid (SHAM),
disulfiram and n-alkyl gallates. The growth Candida albicans was
inhibited by SHAM (Ki = 9-15 mM) and cyanide (Ki = 2-4 mM),
albeit to differing extents. The rate of O2 uptake was inhibited by
less than 10% by 25 mM SHAM and by about 90% by 250 μM
KCN. Although SHAM substantially inhibited the growth of C.
albicans, it is unlikely that the inhibition of AOX was the cause.
Salicylhydroxamic acid is used therapeutically in the treatment of
urinary tract infections and urolithiasis, but it also has some potential
in the treatment of C. albicans infection.
Abstract: Cooktop burners are widely used nowadays. In
cooktop burner design, nozzle efficiency and greenhouse
gas(GHG) emissions mainly depend on heat transfer from the
premixed flame to the impinging surface. This is a complicated
issue depending on the individual and combined effects of various
input combustion variables. Optimal operating conditions for
sustainable burner design were rarely addressed, especially in the
case of multiple slot-jet burners. Through evaluating the optimal
combination of combustion conditions for a premixed slot-jet
array, this paper develops a practical approach for the sustainable
design of gas cooktop burners. Efficiency, CO and NOx emissions
in respect of an array of slot jets using premixed flames were
analysed. Response surface experimental design were applied to
three controllable factors of the combustion process, viz.
Reynolds number, equivalence ratio and jet-to-vessel distance.
Desirability Function Approach(DFA) is the analytic technique
used for the simultaneous optimization of the efficiency and
emission responses.
Abstract: This paper presents the results of a comprehensive
investigation of five blackouts that occurred on 28 August to 8
September 2011 due to bushing failures of the 132/33 kV, 125 MVA
transformers at JBB Ali Grid station. The investigation aims to
explore the root causes of the bushing failures and come up with
recommendations that help in rectifying the problem and avoiding the
reoccurrence of similar type of incidents. The incident reports about
the failed bushings and the SCADA reports at this grid station were
examined and analyzed. Moreover, comprehensive power quality
field measurements at ten 33/11 kV substations (S/Ss) in JBB Ali
area were conducted, and frequency scans were performed to verify
any harmonic resonance frequencies due to power factor correction
capacitors. Furthermore, the daily operations of the on-load tap
changers (OLTCs) of both the 125 MVA and 20 MVA transformers
at JBB Ali Grid station have been analyzed. The investigation
showed that the five bushing failures were due to a local problem, i.e.
internal degradation of the bushing insulation. This has been
confirmed by analyzing the time interval between successive OLTC
operations of the faulty grid transformers. It was also found that
monitoring the number of OLTC operations can help in predicting
bushing failure.
Abstract: This paper describes the shape optimization of impeller
blades for a anti-heeling bidirectional axial flow pump used in ships.
In general, a bidirectional axial pump has an efficiency much lower
than the classical unidirectional pump because of the symmetry of the
blade type. In this paper, by focusing on a pump impeller, the shape of
blades is redesigned to reach a higher efficiency in a bidirectional axial
pump. The commercial code employed in this simulation is CFX v.13.
CFD result of pump torque, head, and hydraulic efficiency was
compared. The orthogonal array (OA) and analysis of variance
(ANOVA) techniques and surrogate model based optimization using
orthogonal polynomial, are employed to determine the main effects
and their optimal design variables. According to the optimal design,
we confirm an effective design variable in impeller blades and explain
the optimal solution, the usefulness for satisfying the constraints of
pump torque and head.
Abstract: The multiple traveling salesman problem (mTSP) can be used to model many practical problems. The mTSP is more complicated than the traveling salesman problem (TSP) because it requires determining which cities to assign to each salesman, as well as the optimal ordering of the cities within each salesman's tour. Previous studies proposed that Genetic Algorithm (GA), Integer Programming (IP) and several neural network (NN) approaches could be used to solve mTSP. This paper compared the results for mTSP, solved with Genetic Algorithm (GA) and Nearest Neighbor Algorithm (NNA). The number of cities is clustered into a few groups using k-means clustering technique. The number of groups depends on the number of salesman. Then, each group is solved with NNA and GA as an independent TSP. It is found that k-means clustering and NNA are superior to GA in terms of performance (evaluated by fitness function) and computing time.
Abstract: Chemical detection is still a continuous challenge when
it comes to designing single-walled carbon nanotube (SWCNT)
sensors with high selectivity, especially in complex chemical
environments. A perfect example of such an environment would be in
thermally oxidized soybean oil. At elevated temperatures, oil oxidizes
through a series of chemical reactions which results in the formation of
monoacylglycerols, diacylglycerols, oxidized triacylglycerols, dimers,
trimers, polymers, free fatty acids, ketones, aldehydes, alcohols,
esters, and other minor products. In order to detect the rancidity of
oxidized soybean oil, carbon nanotube chemiresistor sensors have
been coated with polyethylenimine (PEI) to enhance the sensitivity
and selectivity. PEI functionalized SWCNTs are known to have a high
selectivity towards strong electron withdrawing molecules. The
sensors were very responsive to different oil oxidation levels and
furthermore, displayed a rapid recovery in ambient air without the
need of heating or UV exposure.
Abstract: Due to the emergence of “Humanized Healthcare"
introduced by Professor Dr. Prawase Wasi in 2003[1], the
development of this paradigm tends to be widely implemented. The
organizations included Healthcare Accreditation Institute (public
organization), National Health Foundation, Mahidol University in
cooperation with Thai Health Promotion Foundation, and National
Health Security Office (Thailand) have selected the hospitals or
infirmaries that are qualified for humanized healthcare since 2008-
2010 and 35 of them are chosen to be the outstandingly navigating
organizations for the development of humanized healthcare,
humanized healthcare award [2].
The research aims to study the current issue, characteristics and
patterns of hospital administration contributing to humanized
healthcare system in Thailand. The selected case studies are from
four hospitals including Dansai Crown Prince Hospital, Leoi;
Ubolrattana Hospital, Khon Kaen; Kapho Hospital, Pattani; and
Prathai Hospital, Nakhonrachasima. The methodology is in-depth
interviewing with 10 staffs working as hospital executive directors,
and representatives from leader groups including directors,
multidisciplinary hospital committees, personnel development
committees, physicians and nurses in each hospital. (Total=40) In
addition, focus group discussions between hospital staffs and general
people (including patients and their relatives, the community leader,
and other people) are held by means of setting 4 groups including 8
people within each group. (Total=128) The observation on the
working in each hospital is also implemented. The findings of the
study reveal that there are five important aspects found in each
hospital including (1) the quality improvement under the mental and
spiritual development policy from the chief executives and lead
teams, leaders as Role model and they have visionary leadership; (2)
the participation hospital administration system focusing on learning
process and stakeholder- needs, spiritual human resource
management and development; (3) the relationship among people
especially staffs, team work skills, mutual understanding, effective
communication and personal inner-development; (4) organization
culture relevant to the awareness of patients- rights as well as the
participation policy including spiritual growth achieving to the same
goals, sharing vision, developing public mind, and caring; and (5)
healing structures or environment providing warmth and convenience
for hospital staffs, patients and their relatives and visitors.
Abstract: This research studied the appropriate factors and conditions for laminated bamboo bending by Design of Experiments (DOE). The interested factors affecting the spring back in laminates bamboo were (1) time, (2) thickness, and (3) frequency. This experiment tested the specimen by using high frequency machine and measured its spring back immediately and next 24 hours for comparing the spring back ratio. Results from the experiments showed that significant factors having major influence to bending of laminates bamboo were thickness and frequency. The appropriate conditions of thickness and frequency were 4 mm. and 1.5 respectively.
Abstract: This paper presents an optimization technique to economic load dispatch (ELD) problems with considering the daily load patterns and generator constraints using a particle swarm optimization (PSO). The objective is to minimize the fuel cost. The optimization problem is subject to system constraints consisting of power balance and generation output of each units. The application of a constriction factor into PSO is a useful strategy to ensure convergence of the particle swarm algorithm. The proposed method is able to determine, the output power generation for all of the power generation units, so that the total constraint cost function is minimized. The performance of the developed methodology is demonstrated by case studies in test system of fifteen-generation units. The results show that the proposed algorithm scan give the minimum total cost of generation while satisfying all the constraints and benefiting greatly from saving in power loss reduction
Abstract: This paper proposed a nonlinear model predictive
control (MPC) method for the control of gantry crane. One of the main
motivations to apply MPC to control gantry crane is based on its
ability to handle control constraints for multivariable systems. A
pre-compensator is constructed to compensate the input nonlinearity
(nonsymmetric dead zone with saturation) by using its inverse
function. By well tuning the weighting function matrices, the control
system can properly compromise the control between crane position
and swing angle. The proposed control algorithm was implemented for
the control of gantry crane system in System Control Lab of University
of Technology, Sydney (UTS), and achieved desired experimental
results.
Abstract: This paper investigates the effectiveness of the use of
seismic isolation devices on the overall 3D seismic response of
curved highway viaducts with an emphasis on expansion joints.
Furthermore, an evaluation of the effectiveness of the use of cable
restrainers is presented. For this purpose, the bridge seismic
performance has been evaluated on four different radii of curvature,
considering two cases: restrained and unrestrained curved viaducts.
Depending on the radius of curvature, three-dimensional non-linear
dynamic analysis shows the vulnerability of curved viaducts to
pounding and deck unseating damage. In this study, the efficiency of
using LRB supports combined with cable restrainers on curved
viaducts is demonstrated, not only by reducing in all cases the
possible damage, but also by providing a similar behavior in the
viaducts despite of curvature radius.
Abstract: Traditional multivariate control charts assume that measurement from manufacturing processes follows a multivariate normal distribution. However, this assumption may not hold or may be difficult to verify because not all the measurement from manufacturing processes are normal distributed in practice. This study develops a new multivariate control chart for monitoring the processes with non-normal data. We propose a mechanism based on integrating the one-class classification method and the adaptive technique. The adaptive technique is used to improve the sensitivity to small shift on one-class classification in statistical process control. In addition, this design provides an easy way to allocate the value of type I error so it is easier to be implemented. Finally, the simulation study and the real data from industry are used to demonstrate the effectiveness of the propose control charts.
Abstract: The regulatory competence of blood glucose homeostasis might determine the degree of academic performance. The aim of this study was to produce a model of students' alcohol use based on glucose homeostasis control and cognitive functions that might define the pathogenetic mechanism of alcohol's effect on academic performance. The study took six hours and thirty minutes on fasting, involving thirteen male students. Disturbances in cognitive functions, precisely a decrease in the effectiveness of active attention and a faster development of fatigue after four to six hours of mental work in alcohol users, compared to abstainers was statistically proven. These disturbances in alcohol users were retained even after seven to ten days of moderate alcohol use and might be the reason for the low academic performances among students who use alcoholic beverages.
Abstract: Infrared communication in the wavelength band 780-
950 nm is very suitable for short-range point-to-point communications.
It is a good choice for vehicle-to-vehicle communication in several
intelligent-transportation-system (ITS) applications such as cooperative
driving, collision warning, and pileup-crash prevention. In this
paper, with the aid of a physical model established in our previous
works, we explore the communication area of an infrared intervehicle
communication system utilizing a typical low-cost cormmercial lightemitting
diodes (LEDs) as the emitter and planar p-i-n photodiodes
as the receiver. The radiation pattern of the emitter fabricated by
aforementioned LEDs and the receiving pattern of the receiver are
approximated by a linear combination of cosinen functions. This
approximation helps us analyze the system performance easily. Both
multilane straight-road conditions and curved-road conditions with
various radius of curvature are taken into account. The condition of
a small car communicating with a big truck, i.e., there is a vertical
mounting height difference between the emitter and the receiver, is
also considered. Our results show that the performance of the system
meets the requirement of aforementioned ITS applications in terms
of the communication area.
Abstract: Sorting appears the most attention among all computational tasks over the past years because sorted data is at the heart of many computations. Sorting is of additional importance to parallel computing because of its close relation to the task of routing data among processes, which is an essential part of many parallel algorithms. Many parallel sorting algorithms have been investigated for a variety of parallel computer architectures. In this paper, three parallel sorting algorithms have been implemented and compared in terms of their overall execution time. The algorithms implemented are the odd-even transposition sort, parallel merge sort and parallel rank sort. Cluster of Workstations or Windows Compute Cluster has been used to compare the algorithms implemented. The C# programming language is used to develop the sorting algorithms. The MPI (Message Passing Interface) library has been selected to establish the communication and synchronization between processors. The time complexity for each parallel sorting algorithm will also be mentioned and analyzed.
Abstract: The main mission of Ezilla is to provide a friendly
interface to access the virtual machine and quickly deploy the high
performance computing environment. Ezilla has been developed by
Pervasive Computing Team at National Center for High-performance
Computing (NCHC). Ezilla integrates the Cloud middleware,
virtualization technology, and Web-based Operating System (WebOS)
to form a virtual computer in distributed computing environment. In
order to upgrade the dataset and speedup, we proposed the sensor
observation system to deal with a huge amount of data in the
Cassandra database. The sensor observation system is based on the
Ezilla to store sensor raw data into distributed database. We adopt the
Ezilla Cloud service to create virtual machines and login into virtual
machine to deploy the sensor observation system. Integrating the
sensor observation system with Ezilla is to quickly deploy experiment
environment and access a huge amount of data with distributed
database that support the replication mechanism to protect the data
security.
Abstract: Over the past years, the EMCCD has had a profound
influence on photon starved imaging applications relying on its unique
multiplication register based on the impact ionization effect in the
silicon. High signal-to-noise ratio (SNR) means high image quality.
Thus, SNR improvement is important for the EMCCD. This work
analyzes the SNR performance of an EMCCD with gain off and on. In
each mode, simplified SNR models are established for different
integration times. The SNR curves are divided into readout noise (or
CIC) region and shot noise region by integration time. Theoretical
SNR values comparing long frame integration and frame adding in
each region are presented and discussed to figure out which method is
more effective. In order to further improve the SNR performance,
pixel binning is introduced into the EMCCD. The results show that
pixel binning does obviously improve the SNR performance, but at the
expensive of the spatial resolution.
Abstract: Random Oracle Model (ROM) is an effective method
for measuring the practical security of cryptograph. In this paper, we
try to use it into information hiding system (IHS). Because IHS has its
own properties, the ROM must be modified if it is used into IHS.
Firstly, we fully discuss why and how to modify each part of ROM
respectively. The main changes include: 1) Divide the attacks that IHS
may be suffered into two phases and divide the attacks of each phase
into several kinds. 2) Distinguish Oracles and Black-boxes clearly. 3)
Define Oracle and four Black-boxes that IHS used. 4) Propose the
formalized adversary model. And 5) Give the definition of judge.
Secondly, based on ROM of IHS, the security against known original
cover attack (KOCA-KOCA-security) is defined. Then, we give an
actual information hiding scheme and prove that it is
KOCA-KOCA-secure. Finally, we conclude the paper and propose the
open problems of further research.
Abstract: In this paper, we present a vertical nanowire thin film transistor with gate-all-around architecture, fabricated using CMOS compatible processes. A novel method of fabricating polysilicon vertical nanowires of diameter as small as 30 nm using wet-etch is presented. Both n-type and p-type vertical poly-silicon nanowire transistors exhibit superior electrical characteristics as compared to planar devices. On a poly-crystalline nanowire of 30 nm diameter, high Ion/Ioff ratio of 106, low drain-induced barrier lowering (DIBL) of 50 mV/V, and low sub-threshold slope SS~100mV/dec are demonstrated for a device with channel length of 100 nm.
Abstract: The authors present a mixed method for reducing the order of the large-scale dynamic systems. In this method, the denominator polynomial of the reduced order model is obtained by using the modified pole clustering technique while the coefficients of the numerator are obtained by Pade approximations. This method is conceptually simple and always generates stable reduced models if the original high-order system is stable. The proposed method is illustrated with the help of the numerical examples taken from the literature.