The authors report a case of swine urolithiasis caused
by improper administration of sulfamonomethoxine and which was
diagnosed by examination of urinary sediments and analyzing the
composition of the uroliths. The chemical composition of urinary
calculi obtained from affected pigs with urolithiasis was further
confimed as sulfamonomethoxine by fourier transform infrared
(FTIR). It is suggested that appearance of typical fanlike or wheat
bunchy crystals in urinary sediments under observation of lightmicroscope
and determination by FTIR for the crystals are helpful in
diagnosing sulfa calculi causced swine urolithiasis.
[1] C.M. Kahn, S. Line, S.E. Aiello, The Merck Veterinary Manual, 9th ed.
Merck & Co., Inc, Pennsylvania, 2005, pp1358-1362.
[2] D.M. McCurnin, J. M. Bassert, Clinical Textbook for Veterinary
Technicians, 6th ed. Elsevier Saunders, St. Louis, 2006, pp184-211.
[3] R.A. Manning, B.J. Blaney, Identification of uroliths by infrared
spectroscopy. Australian Veterinary Journal, 1986, 63: 393-396.
[4] J. Kakino, R. Sato, Y. Naito, Purine metabolism of uric acid urolithiasis
induced in newborn piglets. Journal Veterinary Medical Science, 1998,
60(2): 203-206.
[5] D. G. Maes, J. Vrielinck, S. Millet, G. P. Janssens, P. Deprez,
Urolithiasis in finishing pigs. Veterinary Journal, 2004, 168(3): 317-322.
[6] J. Smyth, D. Rice, N. Kavanagh, D. Collins, Urolithiasis in weaned pigs.
The Veterinary Record, 1986, 119: 158-159.
[7] L. Weinstein, M. Madoff, C. Samet, The sulfonamides. New England
Journal Medicine, 1960, 263: 952-957.
[8] J. P. Sasson, P. L. Dratch, M. J. Shortsleeve, Renal US findings in
sulfadiazine-induced crystalluria. Radiology, 1992, 185: 739-740.
[9] B. R. Matlaga, O. D. Shah, D. G. Assimos, Drug-induced urinary calculi.
Review Urology, 2003, 5(4):227-231.
[1] C.M. Kahn, S. Line, S.E. Aiello, The Merck Veterinary Manual, 9th ed.
Merck & Co., Inc, Pennsylvania, 2005, pp1358-1362.
[2] D.M. McCurnin, J. M. Bassert, Clinical Textbook for Veterinary
Technicians, 6th ed. Elsevier Saunders, St. Louis, 2006, pp184-211.
[3] R.A. Manning, B.J. Blaney, Identification of uroliths by infrared
spectroscopy. Australian Veterinary Journal, 1986, 63: 393-396.
[4] J. Kakino, R. Sato, Y. Naito, Purine metabolism of uric acid urolithiasis
induced in newborn piglets. Journal Veterinary Medical Science, 1998,
60(2): 203-206.
[5] D. G. Maes, J. Vrielinck, S. Millet, G. P. Janssens, P. Deprez,
Urolithiasis in finishing pigs. Veterinary Journal, 2004, 168(3): 317-322.
[6] J. Smyth, D. Rice, N. Kavanagh, D. Collins, Urolithiasis in weaned pigs.
The Veterinary Record, 1986, 119: 158-159.
[7] L. Weinstein, M. Madoff, C. Samet, The sulfonamides. New England
Journal Medicine, 1960, 263: 952-957.
[8] J. P. Sasson, P. L. Dratch, M. J. Shortsleeve, Renal US findings in
sulfadiazine-induced crystalluria. Radiology, 1992, 185: 739-740.
[9] B. R. Matlaga, O. D. Shah, D. G. Assimos, Drug-induced urinary calculi.
Review Urology, 2003, 5(4):227-231.
@article{"International Journal of Biological, Life and Agricultural Sciences:56186", author = "Wei-Dong Sun and Ke-Chun Zhang and Jin-Yong Wang and Xiao-Long Wang", title = "Sulfamonomethoxine-Induced Urinary Calculiin Pigs", abstract = "The authors report a case of swine urolithiasis caused
by improper administration of sulfamonomethoxine and which was
diagnosed by examination of urinary sediments and analyzing the
composition of the uroliths. The chemical composition of urinary
calculi obtained from affected pigs with urolithiasis was further
confimed as sulfamonomethoxine by fourier transform infrared
(FTIR). It is suggested that appearance of typical fanlike or wheat
bunchy crystals in urinary sediments under observation of lightmicroscope
and determination by FTIR for the crystals are helpful in
diagnosing sulfa calculi causced swine urolithiasis.", keywords = "Calculi, pig, sulfamonomethoxine.", volume = "3", number = "9", pages = "452-3", }