Profile of Viral Hepatitis in Saudi Arabia

The study was conducted to investigate the profile of
hepatitis in Kingdom of Saudi Arabia, and to determine which age
group hepatitis viruses most commonly infect. The epidemiology of
viral hepatitis in Saudi Arabia has undergone major changes,
concurrent with major socioeconomic developments over the last two
to three decades. This disease represents a major public health
problem in Saudi Arabia resulting in the need for considerable
healthcare resources. A retrospective cross sectional analysis of the
reported cases of viral hepatitis was conducted based on the reports
of The Ministry of Health in Saudi Arabia about Hepatitis A, B and C
infections in all regions from the period of January 2006 to December
2010. The study demonstrated that incidence of viral Hepatitis is
decreasing, except for Hepatitis B that showed minimal increase. Of
hepatitis A, B, and C, Hepatitis B virus (HBV) was the most
predominant type, accounting for (53%) of the cases, followed by
Hepatitis C virus (HCV) (30%) and HAV (17%). HAV infection
predominates in children (5–14 years) with 60% of viral hepatitis
cases, HBV in young adults (15–44 years) with 69% of viral hepatitis
cases, and HCV in older adults (>45 years) with 59% of viral
hepatitis cases. Despite significant changes in the prevalence of viral
hepatitis A, B and C, it remains a major public health problem in
Saudi Arabia; however, it showed a significant decline in the last two
decades that could be attributed to the vaccination programs and the
improved health facilities. Further researches are needed to identify
the risk factors making a specific age group or a specific region in
Saudi Arabia targeted for a specific type of hepatitis viruses.





References:
[1] World Health Organization. Hepatitis B, C and A. World Health Organization Fact Sheet no. 204, 164 and 328 (Revised July 2012).
[2] World Health Organization.Hepatitis C. World Health Organization Fact Sheet no. 164 (Revised July 2012).
[3] World Health Organization.Hepatitis A. World Health Organization Fact Sheet no. 328 (Revised July 2012).
[4] World Health Organization.Hepatitis B Vaccines.WHO Web site. 2003.
[5] Perz JF. The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide. Journal of Hepatology, 2006, 45: 529-38. Epub 2006 Jun 23.
[6] The world health organization.Sixty third-world health assembly 25March 2010.
[7] Regional Committee for the Eastern Mediterranean(56th session), 5 October 2009.
[8] Al Sebayel M, Khalaf H, Al Sofayan M, Al Saghier M, Abdo A, Al Bahili H. Experience with 122 consecutiveliver transplant procedures at King Faisal Specialist Hospital and Research Center. Ann Saudi Med 2007; 27: 333-338.
[9] Ayoola EA, Gadour MO. Hepatocellular carcinoma in Saudi Arabia: role of hepatitis B and C infection. J GastroenterolHepatology 2004; 19: 665-669.
[10] Mansoor I. Experience of liver disease at a University Hospital in Western Saudi Arabia. Saudi Med J 2002; 23: 1070-1073.
[11] Al Rashed R. Prevalence of hepatitis A virus among Saudi Arabian children: A community based study. Annals of Saudi Medicine 1997; 17 (2): 200-203.
[12] Khalil M, Al Mazrou Y, Al Jeffri M, Al Howasi M. Childhood Epidemiology of hepatitis A virus in Riyadh, Saudi Arabia. Annals of Saudi Medicine, Vol 18, No 1, 1998; 18(1): 18-21.
[13] Ministry of Health statistics Book,http://www.moh.gov.sa/en/Ministry/Statistics/Book/Pages/default.aspx; 1427-1431.