Laser Doppler Flowmetry in Diagnostics of Vascular Lesions in Lower Extremities
Laser Doppler flowmetry is a modern method of noninvasive
microcirculation investigation. The aim of our study was to
use this method in the examination of patients with secondary
lymphedema of the lower extremities and obliterating atherosclerosis
of lower extremities. In the analysis of the amplitude-frequency
spectrum of secondary lymphedema patients we have identified
remarkable changes. To describe the changes we used a special
amplitude rate. In both of patients groups this rate was significally
(p<0.05) different with the control group. So the marker phenomena
of the amplitude-frequency spectrum of the LDF signal were
identified. It is suggested that there is a limfodynamics contribution
to the formation of the output signal of laser Doppler flowmetry.
These data have fundamental meaning and are interesting for
practical medicine, as they give an opportunity to further
developments for the use of laser Doppler flowmetry in the
diagnostics and monitoring the effectiveness of the treatment.
[1] N. P. Erofeev, Modern conception of the lymph flow physiology and
treatment of lymphedema of the lower extremities. Saint-Petersburg,
2007, 154 p.
[2] V. I. Konenkov, V. F. Prokofyev, A. V. Shevchenko, E. V. Zonova,
"Cellular, vascular and extracellular components of the lymphatic
system". RAS newsletter #5 (133), 2008, pp. 7-13.
[3] A. I. Krupatkin, V. V. Sidorov, Laser Doppler flowmetry of blood
microcirculation. Moscow: Medicina, 2005, pp. 14-22.
[4] L. V. Orlov, "Laser Doppler flowmetry in medical practice". Kazan
medical journal, vol. 83, #3, 2002, pp.217-218.
[5] V. I. Kozlov, G. A. Azizov, "Mechanism of modulation of the blood
flow and it-s changes during essential arterial hypertension", Regional
Haemodynamics and Microcirculation, vol. 2, 2003, pp. 53-59.
[6] S. G. Abramovich, A. V. Mashanskaya, "Laser Doppler flowmetry in
estimatiom of microcirculation in healthy people and patients with
arterial hypertension". Siberian medical journal, #1, 2010, pp. 57-59.
[7] M. S. Lubarskiy, Edemas of extremities. Novosibirsk, 2004, pp. 41-62.
[1] N. P. Erofeev, Modern conception of the lymph flow physiology and
treatment of lymphedema of the lower extremities. Saint-Petersburg,
2007, 154 p.
[2] V. I. Konenkov, V. F. Prokofyev, A. V. Shevchenko, E. V. Zonova,
"Cellular, vascular and extracellular components of the lymphatic
system". RAS newsletter #5 (133), 2008, pp. 7-13.
[3] A. I. Krupatkin, V. V. Sidorov, Laser Doppler flowmetry of blood
microcirculation. Moscow: Medicina, 2005, pp. 14-22.
[4] L. V. Orlov, "Laser Doppler flowmetry in medical practice". Kazan
medical journal, vol. 83, #3, 2002, pp.217-218.
[5] V. I. Kozlov, G. A. Azizov, "Mechanism of modulation of the blood
flow and it-s changes during essential arterial hypertension", Regional
Haemodynamics and Microcirculation, vol. 2, 2003, pp. 53-59.
[6] S. G. Abramovich, A. V. Mashanskaya, "Laser Doppler flowmetry in
estimatiom of microcirculation in healthy people and patients with
arterial hypertension". Siberian medical journal, #1, 2010, pp. 57-59.
[7] M. S. Lubarskiy, Edemas of extremities. Novosibirsk, 2004, pp. 41-62.
@article{"International Journal of Medical, Medicine and Health Sciences:63849", author = "Petr V. Vasilev and Eduard V. Volkov and Alexej N. Godok and Alexej A and Grischschuk and Vitalij A. Rybalchenko", title = "Laser Doppler Flowmetry in Diagnostics of Vascular Lesions in Lower Extremities", abstract = "Laser Doppler flowmetry is a modern method of noninvasive
microcirculation investigation. The aim of our study was to
use this method in the examination of patients with secondary
lymphedema of the lower extremities and obliterating atherosclerosis
of lower extremities. In the analysis of the amplitude-frequency
spectrum of secondary lymphedema patients we have identified
remarkable changes. To describe the changes we used a special
amplitude rate. In both of patients groups this rate was significally
(p", keywords = "laser Doppler flowmetry, secondary lymphedema of
the lower extremities, obliterating atherosclerosis, non-invasive
diagnostics.", volume = "6", number = "7", pages = "342-4", }