Evaluation of Radiation Synthesized β-Glucan Hydrogel Wound Dressing using Rat Models

In this study, hydrogels consisted of polyvinyl alcohol, propylene glycol and β-glucan were developed by radiation technique for wound dressing. The prepared hydrogels were characterized by examining of physical properties such as gel fraction and absorption ratio. The gel fraction and absorption ratio were dependent on the crosslinking density. On observing the wound healing of rat skin, the resulting hydrogels accelerated the wound healing comparing to cotton gauze. Therefore, the PVA/propylene glycol/β-glucan blended hydrogels can greatly accelerate the healing without causing irritation.

Authors:

• Hui J. Gwon
• Youn M. Lim
• Jong S. Park
• Young C. Nho

Keywords:

• β-Glucan
• poly(vinyl alcohol)
• propylene glycol
• radiation
• wound dressing.

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