Antibacterial and Antifungal Activity Assesment of Nigella Sativa Essential Oils
Antifungal activities of ether and methanolic extracts of volatiles oils of Nigella Sativa seeds were tested against pathogenic bacterias and fungies strains.The volatile oil were found to have significant antifungal and antibacterial activities compare to tetracycline, cefuroxime and ciprofloxacin positive controls.The ether and methanolic esxtracts were compared to each other for antifungal and antibacterial activities and ether extracts showed stonger activity than methanolic one.
[1] Iraz M., 2005 ÔÇö Antiepileptogenic and antioxidant effects of Nigella
sativa oil against pentylenetetrazolinduced kindling in mice.
[2] McCutcheon, A.R., Ellis, S.M., Hancock, R.E. and Towers, G.H., 1992
ÔÇö Antibiotic screening of medicinal plants of the British Colombian
native people. Journal of Ethnopharmacology 37, 212-223.
[3] Swamy S.M.K. and Tan B.K.H.,2000ÔÇöCytotoxic
andimmunopotentiating effects of ethanolic extract of Nigella sativa L.
seeds. Journal of Etnopharmacology, 70: 1-7.Thabrew M.I., Mitry
R.R., Morsy M.A. and
[4] Hughes R.D., 2005 ÔÇö Cytotoxic effects of a decoction of Nigella
sativa, Hemidesmus indicus and Smilaxglabra on human hepatoma
HepG2 cells. LifeSciences, 77: 1319-1330.
[5] Zaoui A., Cherrah Y., Mahassini N., Alaoui K.,Amarouch H. and
Hassar M., 2002 ÔÇö Acute andchronic toxicity of Nigella sativa fixed
oil. Phytomedicine,9: 69-74
[6] Jones ME, Karlowsky JA, Draghi DC, Thornsberry C, Sahn,DF,
Nathwani D. Epidemiology and antibiotic su sceptibility of bacteria
causing skin and s oft tissue infections in t he USA and Europe: a guide
to appropriate antimicrobial therapy. Int J Antimicrob Agents.
2003;22:406-19.
[7] Ali BH, Blunden G. Pharmacolog ical and toxicological properties of
Nigella sativa. Phytother Res. 2003;17:299-305.
[8] Salem ML. Immunomodulatory and therapeutic properties of Nigella
sativa L. Seed. Int Immunopharmacol. 2005;5:1749-70.
[9] Dadgar T, Asmar M, Saifi A, Mazandarani M, Bayat H, Moradi A,
Bazueri M. Antibacterial Activity of Certain Iranian Medicinal Plants
Again st Methicillin-Resistant and Sensitive Staphylococcus aureus .
Asian J Plant Sci.2006;5:861-6.
[10] Lusby PE, Coombes AL, Wilkinso nd JM. Bactericidal activity of
different honeys against pathogenic bacteria. Arch Med Res.
2005;36:464-7.
[11] Mashhadian NV, Rakhshandeh H. Antibacterial and antifungal effects
of Nigella sativa extracts against S. aureus, P.aeroginosa and C.
albicans. Pak J Med Sci. 2005;21
[12] Salem M.L., 2005ÔÇöImmunomodulatory and therapeuti properties of
the Nigella sativa L. seed. InternationalImmunopharmacology, 5: 1749-
1770.
[1] Iraz M., 2005 ÔÇö Antiepileptogenic and antioxidant effects of Nigella
sativa oil against pentylenetetrazolinduced kindling in mice.
[2] McCutcheon, A.R., Ellis, S.M., Hancock, R.E. and Towers, G.H., 1992
ÔÇö Antibiotic screening of medicinal plants of the British Colombian
native people. Journal of Ethnopharmacology 37, 212-223.
[3] Swamy S.M.K. and Tan B.K.H.,2000ÔÇöCytotoxic
andimmunopotentiating effects of ethanolic extract of Nigella sativa L.
seeds. Journal of Etnopharmacology, 70: 1-7.Thabrew M.I., Mitry
R.R., Morsy M.A. and
[4] Hughes R.D., 2005 ÔÇö Cytotoxic effects of a decoction of Nigella
sativa, Hemidesmus indicus and Smilaxglabra on human hepatoma
HepG2 cells. LifeSciences, 77: 1319-1330.
[5] Zaoui A., Cherrah Y., Mahassini N., Alaoui K.,Amarouch H. and
Hassar M., 2002 ÔÇö Acute andchronic toxicity of Nigella sativa fixed
oil. Phytomedicine,9: 69-74
[6] Jones ME, Karlowsky JA, Draghi DC, Thornsberry C, Sahn,DF,
Nathwani D. Epidemiology and antibiotic su sceptibility of bacteria
causing skin and s oft tissue infections in t he USA and Europe: a guide
to appropriate antimicrobial therapy. Int J Antimicrob Agents.
2003;22:406-19.
[7] Ali BH, Blunden G. Pharmacolog ical and toxicological properties of
Nigella sativa. Phytother Res. 2003;17:299-305.
[8] Salem ML. Immunomodulatory and therapeutic properties of Nigella
sativa L. Seed. Int Immunopharmacol. 2005;5:1749-70.
[9] Dadgar T, Asmar M, Saifi A, Mazandarani M, Bayat H, Moradi A,
Bazueri M. Antibacterial Activity of Certain Iranian Medicinal Plants
Again st Methicillin-Resistant and Sensitive Staphylococcus aureus .
Asian J Plant Sci.2006;5:861-6.
[10] Lusby PE, Coombes AL, Wilkinso nd JM. Bactericidal activity of
different honeys against pathogenic bacteria. Arch Med Res.
2005;36:464-7.
[11] Mashhadian NV, Rakhshandeh H. Antibacterial and antifungal effects
of Nigella sativa extracts against S. aureus, P.aeroginosa and C.
albicans. Pak J Med Sci. 2005;21
[12] Salem M.L., 2005ÔÇöImmunomodulatory and therapeuti properties of
the Nigella sativa L. seed. InternationalImmunopharmacology, 5: 1749-
1770.
@article{"International Journal of Medical, Medicine and Health Sciences:63701", author = "Entela Haloci and Stefano Manfredini and Vilma Toska and Silvia Vertuani and Paola Ziosi and Irma Topi and Henri Kolani", title = "Antibacterial and Antifungal Activity Assesment of Nigella Sativa Essential Oils", abstract = "Antifungal activities of ether and methanolic extracts of volatiles oils of Nigella Sativa seeds were tested against pathogenic bacterias and fungies strains.The volatile oil were found to have significant antifungal and antibacterial activities compare to tetracycline, cefuroxime and ciprofloxacin positive controls.The ether and methanolic esxtracts were compared to each other for antifungal and antibacterial activities and ether extracts showed stonger activity than methanolic one.
", keywords = "Antifungal, antibacterial, essential oils, extraction,
Nigella Sativa.", volume = "6", number = "6", pages = "274-3", }
