A Study of Liver Checkup in Patients with Hepatitis C in the Region of Batna

Hepatitis C is an infectious disease transmitted by blood and due to hepatitis C virus (HCV), which attacks the liver. The infection is characterized by liver inflammation (hepatitis) that is often asymptomatic but can progress to chronic hepatitis and later cirrhosis and liver cancer. Our problem tends to highlight on the one hand the prevalence of infectious disease in the population of the region of Batna and on other hand the biological characteristics of this disease by a screening and a specific diagnosis based on serological tests, liver checkup (measurement of haematological and biochemical parameters). The results showed: The serology of hepatitis C establishes the diagnosis of infection with hepatitis C. In this study and with the serological test, 24 cases of the disease of hepatitis C were found in 1000 suspected cases (7 cases with normal transaminases and 17 cases with elevated transaminases). The prevalence of this disease in this study population was 2.4%. The presence of hepatitis C disrupts liver function including the onset of cytolysis, cholestasis, jaundice, thrombocytopenia, and coagulation disorders.

Authors:

• A. Zidani
• M. Yahia K. Belhadi
• S. Benbia

Keywords:

• Disease hepatitis C
• serology
• liver checkup

References:

[1] D. Paul, R. Dominique, (2003). "Virus de l-hépatite C". Elsevier, Ed.
Paris, p. 190, 2003.
[2] A. Piton, T. Poynard, F. Imbert-Bismut, and al, "Factors associated with
serum alanine transaminase activity in healthy subjects: consequences
for the definition of normal values, for selection of blood donors, and for
patients with chronic hepatitis C", Hepatology, vol. 27, pp. 1217-9,
1998.
[3] B. Kronenberger, B. R├╝ster, J. H. Lee, and al, "Hepatocellular
proliferation in patients with chronic hepatitis C and persistently normal
or abnormal aminotransferase levels", Hepatologie, vol. 33, pp. 640-7,
2002.
[4] J. P. Capron, "Augmentation modérée et prolongée de l-activité sérique
des transami-nases", Presse médicale, vol. 18, pp. 913-6, 1989.
[5] E. U. Sotil, D. M. Jensen, "Serum enzymes associated with cholestasis",
Clin Liver Dis, vol. 8, pp. 41-54, 2004.
[6] [6] B. Jean-Pierre, B. Johannes, M. Neil, R. Mario, R. Juan,
"Hépatologie clinique", 2nd ed. Médecine-Sciences Flammarion, Ed.
Paris, p.2148, 2002.
[7] T. Lisman, T. N. Bongers, J. Adelmeijer, H. L. Janssen, MP. de Maat,
PG. de Groot, "Elevated levels of von Willebrand Factor in cirrhosis
support platelet adhesion despite reduced functional capacity",
Hepatology, vol. 44, pp. 53-61, 2006.
[8] C. Eugène, L. Costentin, S. Beaulieu, "Les hépatites virales", 2nd ed.
Masson, Ed. Paris, p. 194, 2004.