Abstract: Recurrence of aneurysm rupture can be attributed to
coil migration and compaction. In order to verify the effects of
hemodynamics on coil compaction and migration, we analyze the
forces and displacements on the coil bundle using a computational
method. Lateral aneurysms partially filled coils are modeled, and
blood flow fields and coil deformations are simulated considering
fluid and solid interaction. Effects of aneurysm neck size and parent
vessel geometry are also investigated. The results showed that coil
deformation was larger in the aneurysms with a wider neck. Parent
vessel geometry and aneurysm neck size also affected mean pressure
force profiles on the coil surface. Pressure forces were higher in wide
neck models with curved parent vessel geometry. Simulation results
showed that coils in the wide neck aneurysm with a curved parent
vessel may be displaced and compacted more easily.
Abstract: Nigella sativa L. is an aromatic plant belonging to the
family Ranunculaceae. It has been used traditionally, especially in the
middle East and India, for the treatment of asthma, cough, bronchitis,
headache, rheumatism, fever, influenza and eczema. Several
biological activities have been reported in Nigella sativa seeds,
including antioxidant. In this context we tried to estimate the
antioxidant activity of various extracts prepared from Nigella sativa
seeds, methanolic extract (ME), chloroformic extract (CE), hexanic
extract (HE : fixed oil), ethyl acetate extract (EAE) water extract
(WE). The Folin-Ciocalteu assay showed that CE and EAE contained
high level of phenolic compounds 81.31 and 72.43μg GAE/mg of
extract respectively. Similarly, the CE and EAE exhibited the highest
DPPH radical scavenging activity, with IC50 values of 106.56μg/ml
and 121.62μg/ml respectively. In addition, CE and HE showed the
most scavenging activity against superoxide radical generated in the
PMS-NADH-NBT system with respective IC50 values of 361.86
μg/ml and 371.80 μg/ml, which is comparable to the activity of the
standard antioxidant BHT (344.59 μg/ml). Ferrous ion chelating
capacity assay showed that WE, EAE and ME are the most active
with 40.57, 39.70 and 22.02 mg EDTA-E/g of extract. The inhibition
of linoleic acid/ß-carotene coupled oxidation was estimated by ßcarotene
bleaching assay, this showed a highest relative antioxidant
activity with CE and EAE (69.82% of inhibition). The antioxidant
activities of the methanolic extract and the fixed oil are confirmed by
an in vivo assay in mice, the daily oral administration of methanolic
extract (500 and 800 mg/kg/day) and fixed oil (2 and 4 ml/kg/day)
during 21 days, resulted in a significant enhancement of the blood
total antioxidant capacity (measured by KRL test) and the plasmatic
antioxidant capacity towards DPPH radical.
Abstract: Hospitals in southern Hualien teamed with the
Hypertension Joint Care Network. Working with the network, the
team provided a special designed health education to the individual
who had been identified as a hypertension patient in the outpatient
department. Some metabolism improvements achieved. This is a
retrospective study by purposively taking 106 patients from a hospital
between 2008 and 2010. Records of before and after education
intervention of the objects was collected and analyzed to see the how
the intervention affected the patients- hypertension control via clinical
parameter monitoring. The results showed that the clinical indicators,
the LDL-C, the cholesterol and the systolic blood pressure were
significantly improved. The study provides evidence for the
effectiveness of the network in controlling hypertension.
Abstract: Sensors possess several properties of physical
measures. Whether devices that convert a sensed signal into an
electrical signal, chemical sensors and biosensors, thus all these
sensors can be considered as an interface between the physical and
electrical equipment. The problem is the analysis of the multitudes of
saved settings as input variables. However, they do not all have the
same level of influence on the outputs. In order to identify the most
sensitive parameters, those that can guide users in gathering
information on the ground and in the process of model calibration
and sensitivity analysis for the effect of each change made.
Mathematical models used for processing become very complex.
In this paper a fuzzy rule-based system is proposed as a solution
for this problem. The system collects the available signals
information from sensors. Moreover, the system allows the study of
the influence of the various factors that take part in the decision
system. Since its inception fuzzy set theory has been regarded as a
formalism suitable to deal with the imprecision intrinsic to many
problems. At the same time, fuzzy sets allow to use symbolic models.
In this study an example was applied for resolving variety of
physiological parameters that define human health state. The
application system was done for medical diagnosis help. The inputs
are the signals expressed the cardiovascular system parameters, blood
pressure, Respiratory system paramsystem was done, it will be able
to predict the state of patient according any input values.
Abstract: It is shown that the relationship of tick-borne
encephalitis virus with the human body comes in two ways, the
development of acute infection with the outcome in convalescence
and long stay by the virus in the body, its persistence in the nervous
tissue with periodic reactivation and prolonged circulating
immunoglobulin M. In spite of the fact that tick-borne encephalitis
virus has a tropism for nerve tissue, involvement in the process of
blood cells is an integral component of the infection. Comprehensive
study of the relation of factors of innate and adaptive immunity in the
tick-borne encephalitis providing insight into the features of chronic
disease.
Abstract: The blood ducts must be occluded to avoid loss of
blood from vessels in laparoscopic surgeries. This paper presents a
locking mechanism to be used in a ligation laparoscopic procedure
(LigLAP I), as an alternative solution for a stapling procedure.
Currently, stapling devices are being used to occlude vessels. Using
these devices may result in some problems, including injury of bile
duct, taking up a great deal of space behind the vessel, and bile leak.
In this new procedure, a two-layer suture occludes a vessel. A
locking mechanism is also required to hold the suture. Since there is
a limited space at the device tip, a Shape Memory Alloy (SMA)
actuator is used in this mechanism. Suitability for cleanroom
applications, small size, and silent performance are among the
advantages of SMA actuators in biomedical applications. An
experimental study is conducted to examine the function of the
locking mechanism. To set up the experiment, a prototype of a
locking mechanism is built using nitinol, which is a nickel-titanium
shape memory alloy. The locking mechanism successfully locks a
polymer suture for all runs of the experiment. In addition, the effects
of various surface materials on the applied pulling forces are studied.
Various materials are mounted at the mechanism tip to compare the
maximum pulling forces applied to the suture for each material. The
results show that the various surface materials on the device tip
provide large differences in the applied pulling forces.
Abstract: Analysis of blood vessel mechanics in normal and
diseased conditions is essential for disease research, medical device
design and treatment planning. In this work, 3D finite element
models of normal vessel and atherosclerotic vessel with 50% plaque
deposition were developed. The developed models were meshed
using finite number of tetrahedral elements. The developed models
were simulated using actual blood pressure signals. Based on the
transient analysis performed on the developed models, the parameters
such as total displacement, strain energy density and entropy per unit
volume were obtained. Further, the obtained parameters were used to
develop artificial neural network models for analyzing normal and
atherosclerotic blood vessels. In this paper, the objectives of the
study, methodology and significant observations are presented.
Abstract: An application of the highly biosensor based on pH-sensitive field immobilized urease for urea analysis was demo The main analytical characteristics of the bios determined; the conditions of urea measureme blood were optimized. A conceptual possibility biosensor for detection of urea concentratio patients suffering from renal insufficiency was sensitive and selective effect transistor and monstrated in this work. iosensor developed were ment in real samples of ility of application of the tion in blood serum of as shown.
Abstract: Ramadan requires individuals to abstain from food and fluid intake between sunrise and sunset; physiological considerations predict that poorer mood, physical performance and mental performance will result. In addition, any difficulties will be worsened because preparations for fasting and recovery from it often mean that nocturnal sleep is decreased in length, and this independently affects mood and performance.
A difficulty of interpretation in many studies is that the observed changes could be due to fasting but also to the decreased length of sleep and altered food and fluid intakes before and after the daytime fasting. These factors were separated in this study, which took place over three separate days and compared the effects of different durations of fasting (4, 8 or 16h) upon a wide variety of measures (including subjective and objective assessments of performance, body composition, dehydration and responses to a short bout of exercise) - but with an unchanged amount of nocturnal sleep, controlled supper the previous evening, controlled intakes at breakfast and daytime naps not being allowed. Many of the negative effects of fasting observed in previous studies were present in this experiment also. These findings indicate that fasting was responsible for many of the changes previously observed, though some effect of sleep loss, particularly if occurring on successive days (as would occur in Ramadan) cannot be excluded.
Abstract: Differentiated impact of team sports (basketball, indoor soccer, handball) on general haemodynamics and aerobic potential of students who specialize in technical subjects is detected only on the fourth year of studies in the institute of higher education. Those who play basketball and indoor soccer have shown increase of stroke and minute volume of blood indices, pumping and contractile function of the heart, oxygenation of blood and oxygen delivery to tissues, aerobic energy supply and balance of sympathetic and parasympathetic activity of the nervous regulation mechanism of the circulatory system. Those who play handball have shown these indices statistically decreased. On the whole playing basketball and indoor soccer optimizes the strategy for adaptation of students to the studying process, but playing handball does the opposite thing. The leading factor for adaptation of students is: those who play basketball have increase of minute blood volume which stipulates velocity of the system blood circulation and well-timed oxygen delivery to tissues; those who play indoor soccer have increase of power and velocity of contractile function of the heart; those who play handball have increase of resistance of thorax to the system blood flow which minimizes contractile function of the heart, blood oxygen saturation and delivery of oxygen to tissues.
Abstract: Goat milk has an hypoallergenic effects, and allergic
diseases related to abnormal of intestinal flora. Probiotic microorganisms
do exert an activity on the immune system in the skin of
the individual.The purpose of this study are to determine the number
of leukocyte and lymphocyte proliferation in rat supplemented with
fermented goat milk (acidophilus milk and kefir) and sensitized with
dinitrochlorobenzene (DNCB). Female Wistar rats 6-8 weeks olds
were divided into 3 treatment groups. The first group supplemented
goat milk kefir, second group acidophilus goat milk, and third group
as control. During 28-day experiment, on day 15 rat sensitized with
allergen DNCB on the dorsal of the body, and on day 24 was
challenged with DNCB on the ear. Sampling of blood and tissue of
intestinal Peyer'patch (PP) were performed on day 14 (before DNCB
sensitized) and on day 28 (after DNCB sensitized). The results
showed the number of neutrophils in rats supplemented with
acidophilus milk was higher (P
Abstract: As nanotechnology advances, the use of nanotechnology for medical purposes in the field of nanomedicine seems more promising; the rise of nanorobots for medical diagnostics and treatments could be arriving in the near future. This study proposes a swarm intelligence based control mechanism for swarm nanorobots that operate as artificial platelets to search for wounds. The canonical particle swarm optimization algorithm is employed in this study. A simulation in the circulatory system is constructed and used for demonstrating the movement of nanorobots with essential characteristics to examine the performance of proposed control mechanism. The effects of three nanorobot capabilities including their perception range, maximum velocity and respond time are investigated. The results show that canonical particle swarm optimization can be used to control the early version nanorobots with simple behaviors and actions.
Abstract: Phase-Contrast MR imaging methods are widely used
for measurement of blood flow velocity components. Also there are
some other tools such as CT and Ultrasound for velocity map
detection in intravascular studies. These data are used in deriving
flow characteristics. Some clinical applications are investigated
which use pressure distribution in diagnosis of intravascular disorders
such as vascular stenosis. In this paper an approach to the problem of
measurement of intravascular pressure field by using velocity field
obtained from flow images is proposed. The method presented in this
paper uses an algorithm to calculate nonlinear equations of Navier-
Stokes, assuming blood as an incompressible and Newtonian fluid.
Flow images usually suffer the lack of spatial resolution. Our
attempt is to consider the effect of spatial resolution on the pressure
distribution estimated from this method. In order to achieve this aim,
velocity map of a numerical phantom is derived at six different
spatial resolutions. To determine the effects of vascular stenoses on
pressure distribution, a stenotic phantom geometry is considered. A
comparison between the pressure distribution obtained from the
phantom and the pressure resulted from the algorithm is presented. In
this regard we also compared the effects of collocated and staggered
computational grids on the pressure distribution resulted from this
algorithm.
Abstract: The counting and analysis of blood cells allows the
evaluation and diagnosis of a vast number of diseases. In particular,
the analysis of white blood cells (WBCs) is a topic of great interest to
hematologists. Nowadays the morphological analysis of blood cells is
performed manually by skilled operators. This involves numerous
drawbacks, such as slowness of the analysis and a nonstandard
accuracy, dependent on the operator skills. In literature there are only
few examples of automated systems in order to analyze the white
blood cells, most of which only partial. This paper presents a
complete and fully automatic method for white blood cells
identification from microscopic images. The proposed method firstly
individuates white blood cells from which, subsequently, nucleus and
cytoplasm are extracted. The whole work has been developed using
MATLAB environment, in particular the Image Processing Toolbox.
Abstract: The Muslim faith requires individuals to fast between
the hours of sunrise and sunset during the month of Ramadan. Our
recent work has concentrated on some of the changes that take place
during the daytime when fasting. A questionnaire was developed to
assess subjective estimates of physical, mental and social activities,
and fatigue. Four days were studied: in the weeks before and after
Ramadan (control days) and during the first and last weeks of
Ramadan (experimental days). On each of these four days, this
questionnaire was given several times during the daytime and once
after the fast had been broken and just before individuals retired at
night.
During Ramadan, daytime mental, physical and social activities
all decreased below control values but then increased to abovecontrol
values in the evening. The desires to perform physical and
mental activities showed very similar patterns. That is, individuals
tried to conserve energy during the daytime in preparation for the
evenings when they ate and drank, often with friends. During
Ramadan also, individuals were more fatigued in the daytime and
napped more often than on control days. This extra fatigue probably
reflected decreased sleep, individuals often having risen earlier
(before sunrise, to prepare for fasting) and retired later (to enable
recovery from the fast).
Some physiological measures and objective measures of
performance (including the response to a bout of exercise) have also
been investigated. Urine osmolality fell during the daytime on
control days as subjects drank, but rose in Ramadan to reach values
at sunset indicative of dehydration. Exercise performance was also
compromised, particularly late in the afternoon when the fast had
lasted several hours. Self-chosen exercise work-rates fell and a set
amount of exercise felt more arduous. There were also changes in
heart rate and lactate accumulation in the blood, indicative of greater
cardiovascular and metabolic stress caused by the exercise in
subjects who had been fasting. Daytime fasting in Ramadan produces
widespread effects which probably reflect combined effects of sleep
loss and restrictions to intakes of water and food.
Abstract: This paper presents the design related to the
electronic system design of the respiratory signal, including phases
for processing, followed by the transmission and reception of this
signal and finally display. The processing of this signal is added to
the ECG and temperature sign, put up last year. Under this scheme is
proposed that in future also be conditioned blood pressure signal
under the same final printed circuit and worked.