Abstract: This study determines the effect of naked and heparinbased
super-paramagnetic iron oxide nanoparticles on the human
cancer cell lines of A2780. Doxorubicin was used as the anticancer
drug, entrapped in the SPIO-NPs. This study aimed to decorate
nanoparticles with heparin, a molecular ligand for 'active' targeting
of cancerous cells and the application of modified-nanoparticles in
cancer treatment. The nanoparticles containing the anticancer drug
DOX were prepared by a solvent evaporation and emulsification
cross-linking method. The physicochemical properties of the
nanoparticles were characterized by various techniques, and uniform
nanoparticles with an average particle size of 110±15 nm with high
encapsulation efficiencies (EE) were obtained. Additionally, a
sustained release of DOX from the SPIO-NPs was successful.
Cytotoxicity tests showed that the SPIO-DOX-HP had higher cell
toxicity than the individual HP and confocal microscopy analysis
confirmed excellent cellular uptake efficiency. These results indicate
that HP based SPIO-NPs have potential uses as anticancer drug
carriers and also have an enhanced anticancer effect.
Abstract: In this paper by measuring the cutting forces the effect
of the tool shape and qualifications (sharp and worn cutting tools of
both vee and knife edge profile) and cutting conditions (depth of cut
and cutting speed) in the turning operation on the tool deflection and
cutting force is investigated. The workpiece material was mild steel
and the cutting tool was made of high speed steel. Cutting forces
were measured by a dynamometer (type P.E.I. serial No 154). The
dynamometer essentially consisted of a cantilever structure which
held the cutting tool. Deflection of the cantilever was measured by an
L.V.D.T (Mercer 122) deflection indicator. No cutting fluid was used
during the turning operations. A modern CNC lathe machine (Okuma
LH35-N) was used for the tests. It was noted that worn vee profile
tools tended to produce a greater increase in the vertical force
component than the axial component, whereas knife tools tended to
show a more pronounced increase in the axial component.
Abstract: The size, complexity and number of databases used
for protein information have caused bioinformatics to lag behind in
adapting to the need to handle this distributed information.
Integrating all the information from different databases into one
database is a challenging problem. Our main research is to develop a
tool which can be used to access and manipulate protein information
from difference databases. In our approach, we have integrated
difference databases such as Swiss-prot, PDB, Interpro, and EMBL
and transformed these databases in flat file format into relational
form using XML and Bioperl. As a result, we showed this tool can
search different sizes of protein information stored in relational
database and the result can be retrieved faster compared to flat file
database. A web based user interface is provided to allow user to
access or search for protein information in the local database.
Abstract: DNA shuffling is a powerful method used for in vitro
evolute molecules with specific functions and has application in areas
such as, for example, pharmaceutical, medical and agricultural
research. The success of such experiments is dependent on a variety
of parameters and conditions that, sometimes, can not be properly
pre-established. Here, two computational models predicting DNA
shuffling results is presented and their use and results are evaluated
against an empirical experiment. The in silico and in vitro results
show agreement indicating the importance of these two models and
motivating the study and development of new models.
Abstract: In this research it is aimed that the effect of some demographic factors on Turkish Adolescents' subjective well being is investigated. 432 adolescents who are 247 girls and 185 boys are participated in this study. They are ages 15-17, and also are high school students. The Positive and Negative Affect Scale and Life Satisfaction Scale are used for measuring adolescents' subjective well being. The ANOVA method is used in order to examine the effect of ages. For gender differences, independent t-test method is used, and finally the Pearson Correlation method is used so as to examine the effect of socio economic statues of adolescents' parents. According to results, there is no gender difference on adolescents' subjective well being. On the other hand, SES and age are effect significantly lover level on adolescents' subjective well being.
Abstract: Structural behavior of ring stiffened thick walled
cylinders made of functionally graded materials (FGMs) is
investigated in this paper. Functionally graded materials are inhomogeneous composites which are usually made from a mixture
of metal and ceramic. The gradient compositional variation of the
constituents from one surface to the other provides an elegant solution to the problem of high transverse shear stresses that are
induced when two dissimilar materials with large differences in material properties are bonded. FGM formation of the cylinder is
modeled by power-law exponent and the variation of characteristics is supposed to be in radial direction.
A finite element formulation is derived for the analysis. According to the property variation of the constituent materials in the radial
direction of the wall, it is not convenient to use conventional elements to model and analyze the structure of the stiffened FGM
cylinders. In this paper a new cylindrical super-element is used to model the finite element formulation and analyze the static and
modal behavior of stiffened FGM thick walled cylinders. By using
this super-element the number of elements, which are needed for
modeling, will reduce significantly and the process time is less in comparison with conventional finite element formulations. Results for static and modal analysis are evaluated and verified by
comparison to finite element formulation with conventional
elements. Comparison indicates a good conformity between results.
Abstract: The join dependency provides the basis for obtaining
lossless join decomposition in a classical relational schema. The
existence of Join dependency shows that that the tables always
represent the correct data after being joined. Since the classical
relational databases cannot handle imprecise data, they were
extended to fuzzy relational databases so that uncertain, ambiguous,
imprecise and partially known information can also be stored in
databases in a formal way. However like classical databases, the
fuzzy relational databases also undergoes decomposition during
normalization, the issue of joining the decomposed fuzzy relations
remains intact. Our effort in the present paper is to emphasize on this
issue. In this paper we define fuzzy join dependency in the
framework of type-1 fuzzy relational databases & type-2 fuzzy
relational databases using the concept of fuzzy equality which is
defined using fuzzy functions. We use the fuzzy equi-join operator
for computing the fuzzy equality of two attribute values. We also
discuss the dependency preservation property on execution of this
fuzzy equi- join and derive the necessary condition for the fuzzy
functional dependencies to be preserved on joining the decomposed
fuzzy relations. We also derive the conditions for fuzzy join
dependency to exist in context of both type-1 and type-2 fuzzy
relational databases. We find that unlike the classical relational
databases even the existence of a trivial join dependency does not
ensure lossless join decomposition in type-2 fuzzy relational
databases. Finally we derive the conditions for the fuzzy equality to
be non zero and the qualification of an attribute for fuzzy key.
Abstract: This paper presents the experimental results on
artificial ageing test of 22 kV XLPE cable for distribution system
application in Thailand. XLPE insulating material of 22 kV cable
was sliced to 60-70 μm in thick and was subjected to ac high voltage
at 23
Ôùª
C, 60
Ôùª
C and 75
Ôùª
C. Testing voltage was constantly applied to
the specimen until breakdown. Breakdown voltage and time to
breakdown were used to evaluate life time of insulating material.
Furthermore, the physical model by J. P. Crine for predicts life time
of XLPE insulating material was adopted as life time model and was
calculated in order to compare the experimental results. Acceptable
life time results were obtained from Crine-s model comparing with
the experimental result. In addition, fourier transform infrared
spectroscopy (FTIR) for chemical analysis and scanning electron
microscope (SEM) for physical analysis were conducted on tested
specimens.
Abstract: The main goal of this paper is to study Statistical Process Control (SPC) with Exponentially Weighted Moving Average (EWMA) control chart when observations are serially-correlated. The characteristic of control chart is Average Run Length (ARL) which is the average number of samples taken before an action signal is given. Ideally, an acceptable ARL of in-control process should be enough large, so-called (ARL0). Otherwise it should be small when the process is out-of-control, so-called Average of Delay Time (ARL1) or a mean of true alarm. We find explicit formulas of ARL for EWMA control chart for Seasonal Autoregressive and Moving Average processes (SARMA) with Exponential white noise. The results of ARL obtained from explicit formula and Integral equation are in good agreement. In particular, this formulas for evaluating (ARL0) and (ARL1) be able to get a set of optimal parameters which depend on smoothing parameter (λ) and width of control limit (H) for designing EWMA chart with minimum of (ARL1).
Abstract: In July 2012, an indoor/outdoor monitoring
programme was undertaken in two university sports facilities: a
fronton and a gymnasium. Comfort parameters (temperature, relative
humidity, CO and CO2) and total volatile organic compounds
(VOCs) were continuously monitored. Concentrations of NO2,
carbonyl compounds and individual VOCs were obtained. Low
volume samplers were used to collect particulate matter (PM10). The
minimum ventilation rates stipulated for acceptable indoor air quality
were observed in both sports facilities. It was found that cleaning
activities may have a large influence on the VOC levels. Acrolein
was one of the most abundant carbonyl compounds, showing
concentrations above the recommended limit. Formaldehyde was
detected at levels lower than those commonly reported for other
indoor environments. The PM10 concentrations obtained during the
occupancy periods ranged between 38 and 43μgm-3 in the fronton and
from 154 to 198μgm-3 in the gymnasium.
Abstract: Aptamers are useful tools in microorganism
researches, diagnoses, and treatment. Aptamers are specific target
molecules formed by oligonucleic acid molecules, and are not
decomposed by alcohol. Aptamers used to detect Mycobacterium
tuberculosis (MTB) have been proved to have specific affinity to the
outer membrane proteins of MTB. This article presents a biosensor
chip set with aptamers for early detection of MTB with high specificity
and sensitivity, even in very low concentration. Meanwhile, we have
already made a modified hydrophobic facial mask module with
internal rendering hydrophobic for effectively collecting M.
tuberculosis.
Abstract: A scalable QoS aware multicast deployment in
DiffServ networks has become an important research dimension in
recent years. Although multicasting and differentiated services are
two complementary technologies, the integration of the two
technologies is a non-trivial task due to architectural conflicts
between them. A popular solution proposed is to extend the
functionality of the DiffServ components to support multicasting. In
this paper, we propose an algorithm to construct an efficient QoSdriven
multicast tree, taking into account the available bandwidth per
service class. We also present an efficient way to provision the
limited available bandwidth for supporting heterogeneous users. The
proposed mechanism is evaluated using simulated tests. The
simulated result reveals that our algorithm can effectively minimize
the bandwidth use and transmission cost
Abstract: The purpose of this study is to identify ideal urban
design elements of waterfronts and to analyze the differences in users-
cognition among these elements. This study follows three steps as
following: first is identifying the urban design elements of waterfronts
from literature review and second is evaluating intended users-
cognition of urban design elements in urban waterfronts. Lastly, third
is analyzing the users- cognition differences. As the result, evaluations
of waterfront areas by users show similar features that non-waterfront
urban design elements contain the highest degree of importance. This
indicates the difference of users- cognition has dimensions of
frequency and distance, and demonstrates differences in the aspect of
importance than of satisfaction. Multi-Dimensional Scaling Method
verifies differences among their cognition. This study provides
elements to increase satisfaction of users from differences of their
cognition on design elements for waterfronts. It also suggests
implications on elements when waterfronts are built.
Abstract: Rice husk is one of the alternative fuels for Thailand because of its high potential and environmental benefits. Nonetheless, the environmental profile of the electricity production from rice husk must be assessed to ensure reduced environmental damage. A 10 MW pilot plant using rice husk as feedstock is the study site. The environmental impacts from rice husk power plant are evaluated by using the Life Cycle Assessment (LCA) methodology. Energy, material and carbon balances have been determined for tracing the system flow. Carbon closure has been used for describing of the net amount of CO2 released from the system in relation to the amount being recycled between the power plant and the CO2 adsorbed by rice husk. The transportation of rice husk to the power plant has significant on global warming, but not on acidification and photo-oxidant formation. The results showed that the impact potentials from rice husk power plant are lesser than the conventional plants for most of the categories considered; except the photo-oxidant formation potential from CO. The high CO from rice husk power plant may be due to low boiler efficiency and high moisture content in rice husk. The performance of the study site can be enhanced by improving the combustion efficiency.
Abstract: This paper presents a new sensor-based online method for generating collision-free near-optimal paths for mobile robots pursuing a moving target amidst dynamic and static obstacles. At each iteration, first the set of all collision-free directions are calculated using velocity vectors of the robot relative to each obstacle and target, forming the Directive Circle (DC), which is a novel concept. Then, a direction close to the shortest path to the target is selected from feasible directions in DC. The DC prevents the robot from being trapped in deadlocks or local minima. It is assumed that the target's velocity is known, while the speeds of dynamic obstacles, as well as the locations of static obstacles, are to be calculated online. Extensive simulations and experimental results demonstrated the efficiency of the proposed method and its success in coping with complex environments and obstacles.
Abstract: The term hybrid composite refers to the composite
containing more than one type of fiber material as reinforcing fillers.
It has become attractive structural material due to the ability of
providing better combination of properties with respect to single fiber
containing composite. The eco-friendly nature as well as processing
advantage, light weight and low cost have enhanced the attraction
and interest of natural fiber reinforced composite. The objective of
present research is to study the mechanical properties of jute-coir
fiber reinforced hybrid polypropylene (PP) composite according to
filler loading variation. In the present work composites were
manufactured by using hot press machine at four levels of fiber
loading (5, 10, 15 and 20 wt %). Jute and coir fibers were utilized at a
ratio of (1:1) during composite manufacturing. Tensile, flexural,
impact and hardness tests were conducted for mechanical
characterization. Tensile test of composite showed a decreasing trend
of tensile strength and increasing trend of the Young-s modulus with
increasing fiber content. During flexural, impact and hardness tests,
the flexural strength, flexural modulus, impact strength and hardness
were found to be increased with increasing fiber loading. Based on
the fiber loading used in this study, 20% fiber reinforced composite
resulted the best set of mechanical properties.
Abstract: The balanced Hamiltonian cycle problemis a quiet new topic of graph theorem. Given a graph G = (V, E), whose edge set can be partitioned into k dimensions, for positive integer k and a Hamiltonian cycle C on G. The set of all i-dimensional edge of C, which is a subset by E(C), is denoted as Ei(C).
Abstract: e-Government structures permits the government to operate in a more transparent and accountable manner of which it increases the power of the individual in relation to that of the government. This paper identifies the factors that determine customer-s attitude towards e-Government services using a theoretical model based on the Technology Acceptance Model. Data relating to the constructs were collected from 200 respondents. The research model was tested using Structural Equation Modeling (SEM) techniques via the Analysis of Moment Structure (AMOS 16) computer software. SEM is a comprehensive approach to testing hypotheses about relations among observed and latent variables. The proposed model fits the data well. The results demonstrated that e- Government services acceptance can be explained in terms of compatibility and attitude towards e-Government services. The setup of the e-Government services will be compatible with the way users work and are more likely to adopt e-Government services owing to their familiarity with the Internet for various official, personal, and recreational uses. In addition, managerial implications for government policy makers, government agencies, and system developers are also discussed.
Abstract: We present a new intuitionistic fuzzy aggregation
operator called the intuitionistic fuzzy ordered weighted
averaging-weighted average (IFOWAWA) operator. The main
advantage of the IFOWAWA operator is that it unifies the OWA
operator with the WA in the same formulation considering the degree
of importance that each concept has in the aggregation. Moreover, it is
able to deal with an uncertain environment that can be assessed with
intuitionistic fuzzy numbers. We study some of its main properties and
we see that it has a lot of particular cases such as the intuitionistic
fuzzy weighted average (IFWA) and the intuitionistic fuzzy OWA
(IFOWA) operator. Finally, we study the applicability of the new
approach on a financial decision making problem concerning the
selection of financial strategies.
Abstract: The precision of heat flux simulation influences the
temperature field and test aberration for TB test and also reflects the
test level for spacecraft development. This paper describes TB tests for
a small satellite using solar simulator, electric heaters, calrod heaters
to evaluate the difference of the three methods. Under the same
boundary condition, calrod heaters cases were about 6oC higher than
solar simulator cases and electric heaters cases for
non-external-heat-flux cases (extreme low temperature cases). While
calrod heaters cases and electric heaters cases were 5~7oC and 2~3oC
lower than solar simulator cases respectively for high temperature
cases. The results show that the solar simulator is better than calrod
heaters for its better collimation, non-homogeneity and stability.