Abstract: A lot of recent research have spoken on the relation
between the increase of the homocysteinemia and some kinds of
cancer . For that, our study was based on the research of a possible
relation between the increase of the concentration of this amino-acid
in the plasma and the appearance of the disease of the Acute
Lymphoblastic Leukaemia in a part of Algerian children with Berber
origin in the East of Algeria . The study has done on 47 ill persons
with an average age of (09±06 ) years , with whom the disease has
diagnosed by blood and marrow examination in the hospital of blood
diseases in the CHU of Batna, and on 194 healthy witnesses of the
same age. The two groups were benefited by a dosage of the
concentration of the homocysteine vitamin B9 ,vitamin B12 , and
also of the study of special polymorphisms of indispensable enzymes
in the metabolism of this acid , and that by the use of the method (
Light cycler ) Real time PCR , on the following enzymes : MS (
C2756G ), MSR ( A66G ) ,MTHFR1 ( C677T ) and MTHFR2
(A1298C). The obtained results have revealed that the rate of the
homozygote muted genotype is the less frequent in the two groups ,
and that exist at list one genotype of each enzyme in the ill group and
in which the percentage exceed with remarkable way the same
genotype in the healthy group and we notice specially the muted
genotype GG of -the methionine synthetase-and the form TT of the
enzyme – methyline tetra hydrofolate reductase – We notice the
existence of considerable number of genotypes in the ill group lied
with characteristic increase of this Amino-acid ,and that for the
reduction of the biologic activity of these enzymes which become
inefficient in the transfer of the homocysteine into the methionine
and cause the diminution of the biologic activity of these enzymes
and with consequence the reduction of the percentage of methylic
radicals in the DNA of studied genes and that lead to the increase of
the activity and the capacity of transcription , and it-s so probably
that this last one is one of the factors of this disease especially if we
know that the specific check-up of vitamins is normal and similar in
the two groups , which ovoid the hypothesis of the reduction of
vitamins . We notice also that the heterozygote genotype is the less in
the sick category except the MTHFR2. Wild genotype is more
frequent in the witness group except MSR. Even these results are
partials; they open a new way in the genetic diagnosis of this
malicious disease which allow a precocious diagnosis and the use of
an effective and appropriated treatment in the same time.
Abstract: Facing the concern of the population to its environment and to climatic change, city planners are now considering the urban climate in their choices of planning. The urban climate, representing different urban morphologies across central Bangkok metropolitan area (BMA), are used to investigates the effects of both the composition and configuration of variables of urban morphology indicators on the summer diurnal range of urban climate, using correlation analyses and multiple linear regressions. Results show first indicate that approximately 92.6% of the variation in the average maximum daytime near-surface air temperature (Ta) was explained jointly by the two composition variables of urban morphology indicators including open space ratio (OSR) and floor area ratio (FAR). It has been possible to determine the membership of sample areas to the local climate zones (LCZs) using these urban morphology descriptors automatically computed with GIS and remote sensed data. Finally result found the temperature differences among zones of large separation, such as the city center could be respectively from 35.48±1.04ºC (Mean±S.D.) warmer than the outskirt of Bangkok on average for maximum daytime near surface temperature to 28.27±0.21ºC for extreme event and, can exceed as 8ºC. A spatially disaggregation of urban thermal responsiveness map would be helpful for several reasons. First, it would localize urban areas concerned by different climate behavior over summer daytime and be a good indicator of urban climate variability. Second, when overlaid with a land cover map, this map may contribute to identify possible urban management strategies to reduce heat wave effects in BMA.
Abstract: Plackett-Burman statistical screening of media
constituents and operational conditions for extracellular lipase
production from isolate Trichoderma viride has been carried out in
submerged fermentation. This statistical design is used in the early
stages of experimentation to screen out unimportant factors from a
large number of possible factors. This design involves screening of
up to 'n-1' variables in just 'n' number of experiments. Regression
coefficients and t-values were calculated by subjecting the
experimental data to statistical analysis using Minitab version 15.
The effects of nine process variables were studied in twelve
experimental trials. Maximum lipase activity of 7.83 μmol /ml /min
was obtained in the 6th trail. Pareto chart illustrates the order of
significance of the variables affecting the lipase production. The
present study concludes that the most significant variables affecting
lipase production were found to be palm oil, yeast extract, K2HPO4,
MgSO4 and CaCl2.
Abstract: Changing technology and increased constituent
demand for government services derive the need for governmental
responsiveness. The government organisations in the developing
countries will be under increased pressure to change their
bureaucratic systems to be able to respond rapidly to changing and
increasing requirements and rapid technology advancements. This
paper aims to present a conceptual framework for explaining the
main barriers and drivers of public e-service development. Therefore,
the framework provides a basic context within which the process and
practice of E-Service can be implemented successfully in the public
sector organisations. The framework is flexible enough to be adopted
by governments at different levels; national or local by developing
countries around the world.
Abstract: While in practice negotiation is always a mix of
cooperation and competition, these two elements correspond to
different approaches of the relationship and also different orientations
in term of strategy, techniques, tactics and arguments employed by
the negotiators with related effects and in the end leading to different
outcomes. The levels of honesty, trust and therefore cooperation are
influenced not only by the uncertainty of the situation, the objectives,
stakes or power but also by the orientation given from the very
beginning of the relationship. When negotiation is reduced to a
confrontation of power, participants rely on coercive measures, using
different kinds of threats or make false promises and bluff in order to
establish a more acceptable balance of power.
Most of the negotiators have a tendency to complain about the
unethical aspects of the tactics used by their counterparts while, as
the same time, they are mostly unaware of the sources of influence of
their own vision and practices. In this article, our intention is to
clarify these sources and try to understand what can lead negotiators
to unethical practices.
Abstract: The effectiveness of consuming a nutrient fortified oat drink on iron, zinc, vitamin A and vitamin C status was assessed among a cohort of school-aged Filipino children. Ultimate study implementation permitted only a within-subject comparison of change in nutritional status after four months of consuming a nutrient fortified oat drink. Thirty-eight anemic children (5-8 years) consumed an oat drink fortified with iron as NaFeEDTA, zinc, vitamin A and vitamin C for 120 days. Height, weight, serum nutrient levels, anemia status and dietary intake were assessed pre and post intervention. Thirty-four anemic children completed the intervention. After 4 months of intervention, prevalence of anemia decreased by 68% and significant improvements in iron and vitamin A status were observed. Results demonstrate the effectiveness of the fortified oat drink in alleviating anemia in young children and highlight the value of fortification programs
Abstract: Needs of an efficient information retrieval in recent
years in increased more then ever because of the frequent use of
digital information in our life. We see a lot of work in the area of
textual information but in multimedia information, we cannot find
much progress. In text based information, new technology of data
mining and data marts are now in working that were started from the
basic concept of database some where in 1960.
In image search and especially in image identification,
computerized system at very initial stages. Even in the area of image
search we cannot see much progress as in the case of text based
search techniques. One main reason for this is the wide spread roots
of image search where many area like artificial intelligence,
statistics, image processing, pattern recognition play their role. Even
human psychology and perception and cultural diversity also have
their share for the design of a good and efficient image recognition
and retrieval system.
A new object based search technique is presented in this paper
where object in the image are identified on the basis of their
geometrical shapes and other features like color and texture where
object-co-relation augments this search process.
To be more focused on objects identification, simple images are
selected for the work to reduce the role of segmentation in overall
process however same technique can also be applied for other
images.
Abstract: Because of its global reach, reduction of time
restraints, and ability to reduce costs and increase sales, use of the
Internet, the World Wide Web (WWW), and related technologies
can be a competitive tool in the arsenal of small and medium-sized
enterprises (SMEs). Countries the world over are interested in the
successful adoption of the Internet by SMEs. Because a vast
majority of jobs come from that sector, greater financial success of
SMEs translates into greater job growth and, subsequently, higher
tax revenue to the government. This research investigated the level
of Internet usage for business solutions by small and medium
enterprises in Jordan. Through the survey of a random sample of
100 firms with less than 500 employees and from data obtained
from this survey that formed the basis for our study, we found that
a majority of respondents use the Internet in business activities ,
the adoption of the Internet as a business tool is limited to a
brochure where Web site which primarily provides one way. As
such, there wasn't interactive information about the company and
its products and services.
Abstract: Concatenative speech synthesis is a method that can
make speech sound which has naturalness and high-individuality of a
speaker by introducing a large speech corpus. Based on this method, in
this paper, we propose a voice conversion method whose conversion
speech has high-individuality and naturalness. The authors also have
two subjective evaluation experiments for evaluating individuality and
sound quality of conversion speech. From the results, following three
facts have be confirmed: (a) the proposal method can convert the
individuality of speakers well, (b) employing the framework of unit
selection (especially join cost) of concatenative speech synthesis into
conventional voice conversion improves the sound quality of
conversion speech, and (c) the proposal method is robust against the
difference of genders between a source speaker and a target speaker.
Abstract: Analytical investigation of the sedimentation
processes in the river engineering and hydraulic structures is of vital
importance as this can affect water supply for the cultivating lands in
the command area. The reason being that gradual sediment formation
behind the reservoir can reduce the nominal capacity of these dams.
The aim of the present paper is to analytically investigate
sedimentation process along the river course and behind the storage
reservoirs in general and the Eastern Intake of the Dez Diversion weir
in particular using the SHARC software. Results of the model
indicated the water level at 115.97m whereas the real time
measurement from the river cross section was 115.98 m which
suggests a significantly close relation between them. The average
transported sediment load in the river was measured at 0.25mm ,
from which it can be concluded that nearly 100% of the suspended
loads in river are moving which suggests no sediment settling but
indicates that almost all sediment loads enters into the intake. It was
further showed the average sediment diameter entering the intake to
be 0.293 mm which in turn suggests that about 85% of suspended
sediments in the river entre the intake. Comparison of the results
from the SHARC model with those obtained form the SSIIM
software suggests quite similar outputs but distinguishing the
SHARC model as more appropriate for the analysis of simpler
problems than other model.
Abstract: Generation system reliability assessment is an
important task which can be performed using deterministic or
probabilistic techniques. The probabilistic approaches have
significant advantages over the deterministic methods. However,
more complicated modeling is required by the probabilistic
approaches. Power generation model is a basic requirement for this
assessment. One form of the generation models is the well known
capacity outage probability table (COPT). Different analytical
techniques have been used to construct the COPT. These approaches
require considerable mathematical modeling of the generating units.
The unit-s models are combined to build the COPT which will add
more burdens on the process of creating the COPT. Decimal to
Binary Conversion (DBC) technique is widely and commonly applied
in electronic systems and computing This paper proposes a novel
utilization of the DBC to create the COPT without engaging in
analytical modeling or time consuming simulations. The simple
binary representation , “0 " and “1 " is used to model the states o f
generating units. The proposed technique is proven to be an effective
approach to build the generation model.
Abstract: An exploratory computational investigation using
RANS & URANS was carried out to understand the aerodynamics
around an isolatedsingle rotating wheel with decreasing ground
proximity. The wheel was initially modeled in free air conditions,
then with decreasing ground proximity and increased yaw angle with
rotational speeds. Three speeds of rotation were applied to the wheel
so that the effect of different angular velocities can be investigated. In
addition to rotation, three different yaw angles were applied to the
rotating wheel in order to understand how these two variables
combined affect the aerodynamic flow field around the wheel.
Abstract: The Tropical Data Hub (TDH) is a virtual research environment that provides researchers with an e-research infrastructure to congregate significant tropical data sets for data reuse, integration, searching, and correlation. However, researchers often require data and metadata synthesis across disciplines for crossdomain analyses and knowledge discovery. A triplestore offers a semantic layer to achieve a more intelligent method of search to support the synthesis requirements by automating latent linkages in the data and metadata. Presently, the benchmarks to aid the decision of which triplestore is best suited for use in an application environment like the TDH are limited to performance. This paper describes a new evaluation tool developed to analyze both features and performance. The tool comprises a weighted decision matrix to evaluate the interoperability, functionality, performance, and support availability of a range of integrated and native triplestores to rank them according to requirements of the TDH.
Abstract: Thrombosis can be life threatening, necessitating therefore its instant treatment. Hydergine, a nootropic agent is used as a cognition enhancer in stroke patients but relatively little is known about its anti-thrombolytic effect. To investigate this aspect, in vivo and ex vivo experiments were designed and conducted. Three groups of rats were injected 1.5mg, 3.0mg and 4.5mg hydergine intraperitonealy with and without prior exposure to fresh plasma. Positive and negative controls were run in parallel. Animals were sacrificed after 1.5hrs and BT, CT, PT, INR, APTT, plasma calcium levels were estimated. For ex vivo analyses, each 1ml blood aspirated was exposed to 0.1mg, 0.2mg, 0.3mg dose of hydergine with parallel controls. Parameters analyzed were as above. Statistical analysis was through one-way ANOVA. Dunken-s and Tukey-s tests provided intra-group variance. BT, CT, PT, INR and APTT increased while calcium levels dropped significantly (P
Abstract: This work presents a numerical model developed to
simulate the dynamics and vibrations of a multistage tractor gearbox.
The effect of time varying mesh stiffness, time varying frictional
torque on the gear teeth, lateral and torsional flexibility of the shafts
and flexibility of the bearings were included in the model. The model
was developed by using the Lagrangian method, and it was applied to
study the effect of three design variables on the vibration and stress
levels on the gears. The first design variable, module, had little effect
on the vibration levels but a higher module resulted to higher bending
stress levels. The second design variable, pressure angle, had little
effect on the vibration levels, but had a strong effect on the stress
levels on the pinion of a high reduction ratio gear pair. A pressure
angle of 25o resulted to lower stress levels for a pinion with 14 teeth
than a pressure angle of 20o. The third design variable, contact ratio,
had a very strong effect on both the vibration levels and bending
stress levels. Increasing the contact ratio to 2.0 reduced both the
vibration levels and bending stress levels significantly. For the gear
train design used in this study, a module of 2.5 and contact ratio of
2.0 for the various meshes was found to yield the best combination
of low vibration levels and low bending stresses. The model can
therefore be used as a tool for obtaining the optimum gear design
parameters for a given multistage spur gear train.
Abstract: Optimal routing in communication networks is a
major issue to be solved. In this paper, the application of Tabu Search
(TS) in the optimum routing problem where the aim is to minimize
the computational time and improvement of quality of the solution in
the communication have been addressed. The goal is to minimize the
average delays in the communication. The effectiveness of Tabu
Search method is shown by the results of simulation to solve the
shortest path problem. Through this approach computational cost can
be reduced.
Abstract: This paper presents the climatic range calculations for
comfort evaporative cooling for Tehran. In this study the minimum
climatic conditions required to achieve an appropriate comfort zone
will be presented.
Physiologically uncomfortable conditions in arid climates are
mainly caused by the extreme heat and dryness. Direct evaporative
cooling adds moisture to the air stream until the air stream is close to
saturation. The dry bulb temperature is reduced, while the wet bulb
temperature stays the same. Evaporative cooling is economical,
effective, environmentally friendly, and healthy.
Comfort cooling by direct evaporative cooling (passive or fan
forced) in the 35. 41 N (such as Tehran) latitude requires design
wet-bulb temperature not over 25.4 C. Evaporative cooling outside
this limit cannot achieve the required 26.7 ET, and is recommended
for relief cooling only.
Abstract: The paper presents the Romanian realities and perspectives from the point of view of reaching the sustainable development model in the context of the recent accession to the European Union, based on the analysis of the indicators listed in the EU Sustainable Development Strategy. The analysis of the economic-social potential for sustainable development and of the environment aspects show that the objectives stipulated in the renewed EU Sustainable Development Strategy of 2006 can be reached, but an extra effort must be put-in in order to overcome the existing substantial gaps in several areas in relation to the developed countries of the EU. The paper-s conclusions show that even if sustainable development is not an easy target to reach in Romania, there are resources and a growing potential, which can lead to sustainable development if used rationally.
Abstract: In this paper, Fabless Prototyping Methodology is
introduced for the design and analysis of MEMS devices.
Conventionally Finite Element Analysis (FEA) is performed before
system level simulation. In our proposed methodology, system level
simulation is performed earlier than FEA as it is computationally less
extensive and low cost. System level simulations are based on
equivalent behavioral models of MEMS device. Electrostatic
actuation based MEMS Microgripper is chosen as case study to
implement this methodology. This paper addresses the behavioral
model development and simulation of actuator part of an
electrostatically actuated Microgripper. Simulation results show that
the actuator part of Microgripper works efficiently for a voltage range
of 0-45V with the corresponding jaw displacement of 0-4.5425μm.
With some minor changes in design, this range can be enhanced to
15μm at 85V.
Abstract: Incremental forming is a complex forming process with
continuously local cumulative deformation taking place during its
process, and springback that forming quality affected by would occur.
The springback evaluation method based on forming error
compensation also was proposed, which it can be defined as the
difference between theory and the actual amount of compensation
along the measured direction. According to forming error
compensation evaluation method, experiments was designed and
implemented. And from the results that obtained it can be show, the
magnitude of springback average (δE) of formed parts was very small,
and the forming precision could be significantly improved by adopting
compensation method. Based on double tensile stress state in the main
deformation area, a hypothesis that there is little springback be arisen
by bending behavior on the formed parts that was proposed.