Abstract: Protein-protein interactions (PPI) play a crucial role in many biological processes such as cell signalling, transcription, translation, replication, signal transduction, and drug targeting, etc. Structural information about protein-protein interaction is essential for understanding the molecular mechanisms of these processes. Structures of protein-protein complexes are still difficult to obtain by biophysical methods such as NMR and X-ray crystallography, and therefore protein-protein docking computation is considered an important approach for understanding protein-protein interactions. However, reliable prediction of the protein-protein complexes is still under way. In the past decades, several grid-based docking algorithms based on the Katchalski-Katzir scoring scheme were developed, e.g., FTDock, ZDOCK, HADDOCK, RosettaDock, HEX, etc. However, the success rate of protein-protein docking prediction is still far from ideal. In this work, we first propose a more practical measure for evaluating the success of protein-protein docking predictions,the rate of first success (RFS), which is similar to the concept of mean first passage time (MFPT). Accordingly, we have assessed the ZDOCK bound and unbound benchmarks 2.0 and 3.0. We also createda new benchmark set for protein-protein docking predictions, in which the complexes have experimentally determined binding affinity data. We performed free energy calculation based on the solution of non-linear Poisson-Boltzmann equation (nlPBE) to improve the binding mode prediction. We used the well-studied thebarnase-barstarsystem to validate the parameters for free energy calculations. Besides,thenlPBE-based free energy calculations were conducted for the badly predicted cases by ZDOCK and ZRANK. We found that direct molecular mechanics energetics cannot be used to discriminate the native binding pose from the decoys.Our results indicate that nlPBE-based calculations appeared to be one of the promising approaches for improving the success rate of binding pose predictions.
Abstract: In this research paper, a slotted coaxial line fed cross
dipole excitation structure for short backfire antenna is proposed and
developed to achieve reconfigurable circular polarization. The cross
dipole, which is fed by the slotted coaxial line, consists of two
orthogonal dipoles. The dipoles are mounted on the outer conductor
of the coaxial line. A unique technique is developed to generate
reconfigurable circular polarization using cross dipole configuration.
The sub-reflector is supported by the feed line, thus requiring no
extra support. The antenna is developed on elliptical ground plane
with dielectric rim making antenna compact. It is demonstrated that
cross dipole excited short backfire antenna can achieve voltage
standing wave ratio (VSWR) bandwidth of 14.28% for 2:1 VSWR,
axial ratio of 0.2 dB with axial ratio (≤ 3dB) bandwidth of 2.14% and
a gain of more than 12 dBi. The experimental results for the designed
antenna structure are in close agreement with computer simulations.
Abstract: The study entitled “The Construction of Interactive
Computer Multimedia Instruction on Basic Japanese Vocabulary"
was aimed: 1) To construct the interactive computer multimedia
instruction on Basic Japanese Vocabulary, 2) To find out
multimedia-s quality, 3) To examine the student-s satisfaction and 4)
To study the learning achievement in Basic Japanese vocabulary. The
sampling group used in this study was composed of 40 1st year
student in Educational Communications and Technology Department,
Faculty of Industrial Education and Technology, King Mongkut-s
University of Technology Thonburi, in the academic year 2553 B.E.
(2010). According to research results, we found that 1). The quality
assessment by 3 mass media experts was at 4.72 on average or at high
level. 2) In terms of contents, the evaluation by 3 experts was at 4.81
on average or at high level. 3) In terms of achievement, there was a
statistical significance between before and after the treatment at the
.05 level. 4) The satisfaction of students towards the interactive
computer multimedia Instruction on “Basic Japanese Vocabulary"
was 4.35 on average, or at high level.
Abstract: This paper presents a smart-card applet that is able to
verify X.509 certificates and to use the public key contained in the
certificate for verifying digital signatures that have been created
using the corresponding private key, e.g. for the purpose of authenticating
the certificate owner against the card. The approach has been
implemented as an operating prototype on Java cards.
Abstract: Calcium magnesium acetate (CMA) is environmentally
benign deicing chemicals that can replace sodium chloride that is
widely used on roads and highways at present for snow and ice control
to provide safe driving conditions during winter. The price of CMA
from petroleum-derived acetic acid is quite expensive. The bamboo
vinegar is the by-product from bamboo charcoal production. The
bamboo vinegar was used to prepare calcium acetate as raw materials,
and its deicing and corrosive performances were studied in this paper.
The results show that the freezing temperature of calcium acetate is
lower than that of sodium chloride when they have same molar
concentration, the deicing performance of calcium acetate is better
than that of sodium chloride when they have same moles, while the
deicing performance of sodium chloride is better than that of calcium
acetate. The corrosion of sodium chloride on iron-nail and steel-nail is
larger than that of calcium acetate whether they have same mass
concentration or same molar concentration, and the corrosion of
sodium chloride and calcium acetate on iron-nail is larger than that on
steel-nail, and calcium acetate almost hasn't corrosion on steel-nail.
Abstract: Two species of Physalis, P.angulataL. and P.
peruviana L. were used as models for comparative study to
understand the values of micro-morphological, -anatomical and
architectural characteristics of leaf for taxonomic purposes and
possibly breeding and commercial applications. Both speciespossess
amphistomaticleaves with 1-layer epidermis, 3-4-layer spongy
mesophyll andbicollateral bundle midrib. Palisade parenchyma cells
of P. angulatawere almost twice longer (65-75 μm) than the other
one. Type of stomata was similar as anomocyticbut stomatal
index(SI) at adaxial surface and abaxial surface of P. angulata were
less than of P. peruvianaas 3.57, 4.00 and6.25, 6.66 respectively.
Some leaf architectural characteristics such as leaf shape, order of
venationalsoprovided information of taxonomic significance
Abstract: Interpolated contour maps drawn for aluminum,
copper and molybdenum in downstream monitoring boreholes of
water dam in Miduk Copper Complex and the values of pH, redox
potential (Eh) and distance from water dam indicate different trends
of variation and behavior of these three elements in downward
groundwater resources. As these maps exhibit, aluminum is dominant
in the most alkaline (pH = 9-11) borehole (MB5) to water dam. The
highest concentration of molybdenum is found in the nearest
borehole (MB6) to water dam. Main concentration of copper is
observed in the most oxidized borehole (MB3 with Eh=293.2mV).
The spatial difference among sampling stations can be attributed to
the existence of faults and diaclases in the geologic structure of
Miduk region which causes the groundwater sampling sites to be
impressed by different contamination sources (toe seepage and upper
seepage water originated from different zones of tailings dump).
Abstract: In this paper we present a novel error model for
packet loss and subsequent error description. The proposed model
simulates the error performance of wireless communication link. The
model is designed as two independent Markov chains, where the first
one is used for packet generation and the second one generates
correctly and incorrectly transmitted bits for received packets from
the first chain. The statistical analyses of real communication on the
wireless link are used for determination of model-s parameters. Using
the obtained parameters and the implementation of the generator, we
collected generated traffic. The obtained results generated by
proposed model are compared with the real data collection.
Abstract: This paper highlights some interesting facts on South African-s waste situation and management strategies, in particular the Integrated Waste Management. South Africa supports a waste hierarchy by promoting cleaner production, waste minimisation, reuse, recycling and waste treatment with disposal and remediation as the last preferred options in waste management. The drivers for waste management techniques are identified as increased demand for waste service provision; increased demand for waste minimisation; recycling and recovery; land use, physical and environmental limitations; and socio-economic and demographic factors. The South African government recognizes the importance of scientific research as outlined on the white paper on Integrated Pollution and Waste Management (IP and WM) (DEAT, 2000).
Abstract: This study was conducted to examine the effects of ketum extract on development of Chrysomya rufifacies and to analyze the presence of mitragynine in the larvae samples. 110 newly emerged first instar larvae of C. rufifacies were introduced on ketum extract-mixed cow liver at doses of 0, 20, 40 and 60g. Blowfly development rate was determined with 12 hour intervals and
mitragynine in larvae was extracted and quantitated. C. rufifacies in control group took about 192 hours to complete their development from first instar larvae to adult blowfly; meanwhile blowfly form from the highest dose of ketum was 264 hours. Mitragynine was detected in all groups of treatment, except for control. In conclusion, the presence of mitragynine in C. rufifacies is affected in delaying development rates of the blowfly for up to 62 hours or 3 days. Chemical analysis of mitragynine from larvae samples showed that this alkaloid present in all specimens analyzed.
Abstract: This study investigates the investors- behavioral
reaction to the investment rating change announcements from the
views of behavioral finance. The empirical results indicate that
self-interest does affect the intention of securities firms to release
investment ratings for individual stocks. In addition, behavioral
pitfalls are also found in the response of retail investors to investment
rating change announcements.
Abstract: A novel feature selection strategy to improve the recognition accuracy on the faces that are affected due to nonuniform illumination, partial occlusions and varying expressions is proposed in this paper. This technique is applicable especially in scenarios where the possibility of obtaining a reliable intra-class probability distribution is minimal due to fewer numbers of training samples. Phase congruency features in an image are defined as the points where the Fourier components of that image are maximally inphase. These features are invariant to brightness and contrast of the image under consideration. This property allows to achieve the goal of lighting invariant face recognition. Phase congruency maps of the training samples are generated and a novel modular feature selection strategy is implemented. Smaller sub regions from a predefined neighborhood within the phase congruency images of the training samples are merged to obtain a large set of features. These features are arranged in the order of increasing distance between the sub regions involved in merging. The assumption behind the proposed implementation of the region merging and arrangement strategy is that, local dependencies among the pixels are more important than global dependencies. The obtained feature sets are then arranged in the decreasing order of discriminating capability using a criterion function, which is the ratio of the between class variance to the within class variance of the sample set, in the PCA domain. The results indicate high improvement in the classification performance compared to baseline algorithms.
Abstract: There has been considerable growth in the issue of
food & beverage safety in Thailand. This is important because the
level of satisfaction in food & beverage safety has impacts on travel
decision made by foreign tourists. Therefore, this paper was aimed to
test if there is any significant gender effect in the level of satisfaction
of food & beverage safety made by foreign tourists in Thailand. In
addition, this paper utilized the Chi Square test of independent to test
if there was an association between gender and sickness because of
food and if there was an association between gender and the
perception of food safety standard. During January to June, 2012, a
total of 400 foreign tourist respondents, 200 male as well as 200
female foreign tourists, were interviewed at the departure lounge at
Suvarnabhumi airport, Thailand. The findings revealed the
astonishing result that there was no significant effect of gender. Also,
there was no significant difference in the association between gender
and being sick because of food as well as the association between
gender and the perception on the standard of food safety during their
trip in Thailand.
Abstract: Supply network management adopts a systematic
and integrative approach to managing the operations and
relationships of various parties in a supply network. The objective
of the manufactures in their supply network is to reduce inventory
costs and increase customer satisfaction levels. One way of doing
that is to synchronize delivery performance. A supply network can
be described by nodes representing the companies and the links
(relationships) between these nodes. Uncertainty in delivery time
depends on type of network relationship between suppliers. The
problem is to understand how the individual uncertainties influence
the total uncertainty of the network and identify those parts of the
network, which has the highest potential for improving the total
delivery time uncertainty.
Abstract: The present study was carried out to evaluate the
nutritional value of sorghum flour during processing of injera
(unleavened thick bread). The proximate composition of sorghum
flour before and after fermentation and that of injera was determined.
Compared to the raw flour and fermented one, injera had low protein
(11.55%), ash (1.57%) and fat (2.40%) contents but high in fiber
content. Moreover, injera was found to have significantly (P ≤ 0.05)
higher energy (389.08 Kcal/100g) compared to raw and fermented
sorghum flour. Injera contained lower levels of anti-nutritional
factors (polyphenols, phytate and tannins) compared to raw and
fermented sorghum. Also it was found to be rich in Ca
(4.75mg/100g), Fe (3.95 mg/100g), and Cu (0.7 mg/100g) compared
to that of raw and fermented flour. Moreover, both the extractable
minerals and protein digestibility were high for injera due to low
amount of anti-nutrients. Injera was found to contain an appreciable
amount of amino acids except arginine and tyrosine.
Abstract: The effect of cross linking of the protein isolates of
three legumes with the microbial enzyme transglutaminase (EC
2.3.2.13) on the functional properties at different NaCl concentration
was studied. The reduction in the total free amino groups (OD340) of
the polymerized protein showed that TGase treatment cross-linking
the protein subunit of each legume. The solubility of the protein
polymer of each legume was greatly improved at high concentration
of NaCl. At 1.2 M NaCl the solubility of the native legumes protein
was significantly decreased but after polymerization slightly
improved. Cross linked proteins were less turbid on heating to higher
temperature as compared to native proteins and the temperature at
which the protein turns turbid also increased in the polymerized
proteins. The emulsifying and foaming properties of the protein
polymer were greatly improved at all concentrations of NaCl for all
legumes.
Abstract: In this paper, the Fuzzy Autocatalytic Set (FACS) is
composed into Omega Algebra by embedding the membership value
of fuzzy edge connectivity using the property of transitive affinity.
Then, the Omega Algebra of FACS is a transformation semigroup
which is a special class of semigroup is shown.
Abstract: Several researchers have proposed methods about
combination of Genetic Algorithm (GA) and Fuzzy Logic (the use of
GA to obtain fuzzy rules and application of fuzzy logic in
optimization of GA). In this paper, we suggest a new method in
which fuzzy decision making is used to improve the performance of
genetic algorithm. In the suggested method, we determine the alleles
that enhance the fitness of chromosomes and try to insert them to the
next generation.
In this algorithm we try to present an innovative vaccination in the
process of reproduction in genetic algorithm, with considering the
trade off between exploration and exploitation.
Abstract: Business Process Management (BPM) helps in optimizing the business processes inside an enterprise. But BPM architecture does not provide any help for extending the enterprise. Modern business environments and rapidly changing technologies are asking for brisk changes in the business processes. Service Oriented Architecture (SOA) can help in enabling the success of enterprise-wide BPM. SOA supports agility in software development that is directly related to achieve loose coupling of interacting software agents. Agility is a premium concern of the current software designing architectures. Together, BPM and SOA provide a perfect combination for enterprise computing. SOA provides the capabilities for services to be combined together and to support and create an agile, flexible enterprise. But there are still many questions to answer; BPM is better or SOA? and what is the future track of BPM and SOA? This paper tries to answer some of these important questions.
Abstract: The objective of this paper is to present a
comparative study of Homotopy Perturbation Method (HPM),
Variational Iteration Method (VIM) and Homotopy Analysis
Method (HAM) for the semi analytical solution of Kortweg-de
Vries (KdV) type equation called KdV. The study have been
highlighted the efficiency and capability of aforementioned methods
in solving these nonlinear problems which has been arisen from a
number of important physical phenomenon.