Abstract: The aim of this article is to narrate the utility of novel simulation approach i.e. convolution method to predict blood concentration of drug utilizing dissolution data of salbutamol sulphate microparticulate formulations with different release patterns (1:1, 1:2 and 1:3, drug:polymer). Dissolution apparatus II USP 2007 and 900 ml double distilled water stirrd at 50 rpm was employed for dissolution analysis. From dissolution data, blood drug concentration was determined, and in return predicted blood drug concentration data was used to calculate the pharmacokinetic parameters i.e. Cmax, Tmax, and AUC. Convolution is a good biwaiver technique; however its better utility needs it application in the conditions where biorelevant dissolution media are used.
Abstract: The need of high frame-rate imaging has been triggered by the new applications of ultrasound imaging to transient elastography and real-time 3D ultrasound. Using plane wave excitation (PWE) is one of the methods to achieve very high frame-rate imaging since an image can be formed with a single insonification. However, due to the lack of transmit focusing, the image quality with PWE is lower compared with those using conventional focused transmission. To solve this problem, we propose a filter-retrieved transmit focusing (FRF) technique combined with cross-correlation weighting (FRF+CC weighting) for high frame-rate imaging with PWE. A restrospective focusing filter is designed to simultaneously minimize the predefined sidelobe energy associated with single PWE and the filter energy related to the signal-to-noise-ratio (SNR). This filter attempts to maintain the mainlobe signals and to reduce the sidelobe ones, which gives similar mainlobe signals and different sidelobes between the original PWE and the FRF baseband data. Normalized cross-correlation coefficient at zero lag is calculated to quantify the degree of similarity at each imaging point and used as a weighting matrix to the FRF baseband data to further suppress sidelobes, thus improving the filter-retrieved focusing quality.
Abstract: In this paper, we proposed the effects of Mo thickness
on the properties of AZO/Mo/AZO multilayer thin films for
opto-electronics applications. The structural, optical and electrical
properties of AZO/Mo/AZO thin films were investigated.
Optimization of the thin films coatings resulted with low resistivity of
9.98 × 10-5 )-cm, mobility of 12.75 cm2/V-s, carrier concentration of
1.05 × 1022 cm-3, maximum transmittance of 79.13% over visible
spectrum of 380 – 780 nm and Haacke figure of merit (FOM) are 5.95
× 10-2 )-1 under Mo layer thickness of 15 nm. These results indicate an
alternative candidate for use as a transparent electrode in solar cells
and various displays applications.
Abstract: The implementation of electronic government started since the initiation of Multimedia Super Corridor (MSC) by the Malaysia government. The introduction of ICT in the public sector especially e-Government initiatives opens up a new book in the government administration throughout the world. The aim or this paper is to discuss the implementation of e-government in Malaysia, covering the result of public user self assessment on Malaysia's electronic government applications. E-services, e-procurement, Generic Office Environment (GOE), Human Resources Management Information System (HRMIS), Project Monitoring System (PMS), Electronic Labor Exchange (ELX) and e-syariah(religion) were the seven flagship application assessed. The study adopted a crosssectional survey research approach and information system literature were used. The analysis was done for 35 responden in pilot test and there was evidence from public user's perspective to suggest that the e-government applications were generally successful.
Abstract: The high temperature degree and uniform
Temperature Distribution (TD) on surface of cookware which contact
with food are effective factors for improving cookware application.
Additionally, the ability of pan material in retaining the heat and nonreactivity
with foods are other significant properties. It is difficult for
single material to meet a wide variety of demands such as superior
thermal and chemical properties. Multi-Layer Plate (MLP) makes
more regular TD. In this study the main objectives are to find the best
structure (single or multi-layer) and materials to provide maximum
temperature degree and uniform TD up side surface of pan. And also
heat retaining of used metals with goal of improving the thermal
quality of pan to economize the energy. To achieve this aim were
employed Finite Element Method (FEM) for analyzing transient
thermal behavior of applied materials. The analysis has been
extended for different metals, we achieved the best temperature
profile and heat retaining in Copper/ Stainless Steel MLP.
Abstract: This research investigates the design of a low-cost 3D
spatial interaction approach using the Wii Remote for immersive
Head-Mounted Display (HMD) virtual reality. Current virtual reality
applications that incorporate the Wii Remote are either desktop
virtual reality applications or systems that use large screen displays.
However, the requirements for an HMD virtual reality system differ
from such systems. This is mainly because in HMD virtual reality,
the display screen does not remain at a fixed location. The user views
the virtual environment through display screens that are in front of
the user-s eyes and when the user moves his/her head, these screens
move as well. This means that the display has to be updated in realtime
based on where the user is currently looking. Normal usage of
the Wii Remote requires the controller to be pointed in a certain
direction, typically towards the display. This is too restrictive for
HMD virtual reality systems that ideally require the user to be able to
turn around in the virtual environment. Previous work proposed a
design to achieve this, however it suffered from a number of
drawbacks. The aim of this study is to look into a suitable method of
using the Wii Remote for 3D interaction in a space around the user
for HMD virtual reality. This paper presents an overview of issues
that had to be considered, the system design as well as experimental
results.
Abstract: On-line handwritten scripts are usually dealt with pen tip traces from pen-down to pen-up positions. Time evaluation of the pen coordinates is also considered along with trajectory information. However, the data obtained needs a lot of preprocessing including filtering, smoothing, slant removing and size normalization before recognition process. Instead of doing such lengthy preprocessing, this paper presents a simple approach to extract the useful character information. This work evaluates the use of the counter- propagation neural network (CPN) and presents feature extraction mechanism in full detail to work with on-line handwriting recognition. The obtained recognition rates were 60% to 94% using the CPN for different sets of character samples. This paper also describes a performance study in which a recognition mechanism with multiple thresholds is evaluated for counter-propagation architecture. The results indicate that the application of multiple thresholds has significant effect on recognition mechanism. The method is applicable for off-line character recognition as well. The technique is tested for upper-case English alphabets for a number of different styles from different peoples.
Abstract: Application of pesticides in the paddy fields has
deleterious effects on non-target organisms including cyanobacteria
which are photosynthesizing and nitrogen fixing micro-organisms
contributing significantly towards soil fertility and crop yield.
Pesticide contamination in the paddy fields has manifested into a
serious global environmental concern. To study the effect of one such
pesticide, three cyanobacterial strains; Anabaena fertilissima,
Aulosira fertilissima and Westiellopsis prolifica were selected for
their stress responses to an Organochlorine insecticide - 6, 7, 8, 9, 10,
10-hexachloro-1, 5, 5a, 6, 9, 9a-hexahydro-6, 9-methano-2, 4, 3-
benzodioxathiepine-3-oxide, with reference to their photosynthesic
pigments-chlorophyll-a and carotenoids as well as accessory
pigments-phycobiliproteins (phycocyanin, allophycocyanin and
phycoerythrin), stress induced biochemical metabolites like
carbohydrates, proteins, amino acids, phenols and enzymes-nitrate
reductase, glutamine synthetase and succinate dehydrogenase. All
the three cyanobacterial strains were adversely affected by the
insecticide doses and inhibition was dose dependent. Reduction in
photosynthetic and accessory pigments, metabolites, nitrogen fixing
and respiratory enzymes of the test organisms were accompanied
with an initial increase in their total protein at lower Organochlorine
doses. On the other hand, increased amount of phenols in all the
insecticide treated concentrations was indicative of stressed activities
of the organisms.
Abstract: Most real world systems express themselves formally
as a set of nonlinear algebraic equations. As applications grow, the
size and complexity of these equations also increase. In this work, we
highlight the key concepts in using the homotopy analysis method
as a methodology used to construct efficient iteration formulas for
nonlinear equations solving. The proposed method is experimentally
characterized according to a set of determined parameters which
affect the systems. The experimental results show the potential and
limitations of the new method and imply directions for future work.
Abstract: This paper introduces the application of seismic wave method in earthquake prediction and early estimation. The advantages of the seismic wave method over the traditional earthquake prediction method are demonstrated. An example is presented in this study to show the accuracy and efficiency of using the seismic wave method in predicting a medium-sized earthquake swarm occurred in Wencheng, Zhejiang, China. By applying this method, correct predictions were made on the day after this earthquake swarm started and the day the maximum earthquake occurred, which provided scientific bases for governmental decision-making.
Abstract: This paper describes the performance of TCP Vegas
over the wireless IPv6 network. The performance of TCP Vegas is
evaluated using network simulator (ns-2). The simulation experiment
investigates how packet spacing affects the network delay, network
throughput and network efficiency of TCP Vegas. Moreover, we
investigate how the variable FTP packet sizes affect the network
performance. The result of the simulation experiment shows that as
the packet spacing is implements, the network delay is reduces,
network throughput and network efficiency is optimizes. As the FTP
packet sizes increase, the ratio of delay per throughput decreases.
From the result of experiment, we propose the appropriate packet size
in transmitting file transfer protocol application using TCP Vegas
with packet spacing enhancement over wireless IPv6 environment in
ns-2. Additionally, we suggest the appropriate ratio in determining
the appropriate RTT and buffer size in a network.
Abstract: Realistic 3D face model is more precise in representing
pose, illumination, and expression of face than 2D face model so that it
can be utilized usefully in various applications such as face recognition,
games, avatars, animations, and etc.
In this paper, we propose a 3D face modeling method based on 3D
dense morphable shape model. The proposed 3D modeling method
first constructs a 3D dense morphable shape model from 3D face scan
data obtained using a 3D scanner. Next, the proposed method extracts
and matches facial landmarks from 2D image sequence containing a
face to be modeled, and then reconstructs 3D vertices coordinates of
the landmarks using a factorization-based SfM technique. Then, the
proposed method obtains a 3D dense shape model of the face to be
modeled by fitting the constructed 3D dense morphable shape model
into the reconstructed 3D vertices. Also, the proposed method makes a
cylindrical texture map using 2D face image sequence. Finally, the
proposed method generates a 3D face model by rendering the 3D dense
face shape model using the cylindrical texture map. Through building
processes of 3D face model by the proposed method, it is shown that
the proposed method is relatively easy, fast and precise.
Abstract: Electronic commerce is growing rapidly with on-line
sales already heading for hundreds of billion dollars per year. Due to
the huge amount of money transferred everyday, an increased
security level is required. In this work we present the architecture of
an intelligent speaker verification system, which is able to accurately
verify the registered users of an e-commerce service using only their
voices as an input. According to the proposed architecture, a
transaction-based e-commerce application should be complemented
by a biometric server where customer-s unique set of speech models
(voiceprint) is stored. The verification procedure requests from the
user to pronounce a personalized sequence of digits and after
capturing speech and extracting voice features at the client side are
sent back to the biometric server. The biometric server uses pattern
recognition to decide whether the received features match the stored
voiceprint of the customer who claims to be, and accordingly grants
verification. The proposed architecture can provide e-commerce
applications with a higher degree of certainty regarding the identity
of a customer, and prevent impostors to execute fraudulent
transactions.
Abstract: Intuitionistic fuzzy sets as proposed by Atanassov,
have gained much attention from past and latter researchers for
applications in various fields. Similarity measures between
intuitionistic fuzzy sets were developed afterwards. However, it does
not cater the conflicting behavior of each element evaluated. We
therefore made some modification to the similarity measure of IFS
by considering conflicting concept to the model. In this paper, we
concentrate on Zhang and Fu-s similarity measures for IFSs and
some examples are given to validate these similarity measures. A
simple modification to Zhang and Fu-s similarity measures of IFSs
was proposed to find the best result according to the use of degree of
indeterminacy. Finally, we mark up with the application to real
decision making problems.
Abstract: The Tropical Data Hub (TDH) is a virtual research environment that provides researchers with an e-research infrastructure to congregate significant tropical data sets for data reuse, integration, searching, and correlation. However, researchers often require data and metadata synthesis across disciplines for crossdomain analyses and knowledge discovery. A triplestore offers a semantic layer to achieve a more intelligent method of search to support the synthesis requirements by automating latent linkages in the data and metadata. Presently, the benchmarks to aid the decision of which triplestore is best suited for use in an application environment like the TDH are limited to performance. This paper describes a new evaluation tool developed to analyze both features and performance. The tool comprises a weighted decision matrix to evaluate the interoperability, functionality, performance, and support availability of a range of integrated and native triplestores to rank them according to requirements of the TDH.
Abstract: High Power Lasers produce an intense burst of
Bremmstrahlung radiation which has potential applications in broadband
x-ray radiography. Since the radiation produced is through the
interaction of accelerated electrons with the remaining laser target,
these bursts are extremely short – in the region of a few ps. As a
result, the laser-produced x-rays are capable of imaging complex
dynamic objects with zero motion blur.
Abstract: Raw wood vinegar was purified by both standing and
filtering methods. Toxicity tests were conducted under laboratory
conditions by the topical application method (contact poison) and
feeding method (stomach poison). Larvicidal activities of wood
vinegar at four different concentrations (10, 15, 20, 25 and 30 %)
were studied against second instar larvae of housefly (Musca
domestica L.). Four replicates were maintained for all treatments and
controls. Larval mortality was recorded up to 96 hours and compared
with the larval survivability by two methods of larvicidal bioassay.
Percent pupation and percent adult emergence were observed in
treated M. domestica. The study revealed that the feeding method
gave higher efficiency compared with the topical application method.
Larval mortality increased with increasing concentration of wood
vinegar and the duration of exposure. No mortality was found in
treated M. domestica larvae at minimum 10% concentration of wood
vinegar through the experiments. The treated larvae were maintained
up to pupa and adult emergence. At 30% maximum concentration
larval duration was extended to 11 days in M. domestica for topical
application method and 9 days for feeding method. Similarly the
pupal durations were also increased with increased concentrations
(16 and 24 days for topical application method and feeding method
respectively at 30% concentration) of the treatments.
Abstract: Optimal routing in communication networks is a
major issue to be solved. In this paper, the application of Tabu Search
(TS) in the optimum routing problem where the aim is to minimize
the computational time and improvement of quality of the solution in
the communication have been addressed. The goal is to minimize the
average delays in the communication. The effectiveness of Tabu
Search method is shown by the results of simulation to solve the
shortest path problem. Through this approach computational cost can
be reduced.
Abstract: In this paper, genetic algorithm (GA) opmization technique is applied to design Flexible AC Transmission System (FACTS)-based damping controllers. Two types of controller structures, namely a proportional-integral (PI) and a lead-lag (LL) are considered. The design problem of the proposed controllers is formulated as an optimization problem and GA is employed to search for optimal controller parameters. By minimizing the time-domain based objective function, in which the deviation in the oscillatory rotor speed of the generator is involved; stability performance of the system is improved. The proposed controllers are tested on a weakly connected power system subjected to different disturbances. The non-linear simulation results are presented to show the effectiveness of the proposed controller and their ability to provide efficient damping of low frequency oscillations. It is also observed that the proposed SSSC-based controllers improve greatly the voltage profile of the system under severe disturbances. Further, the dynamic performances of both the PI and LL structured FACTS-controller are analyzed at different loading conditions and under various disturbance condition as well as under unbalanced fault conditions..
Abstract: The present work deals with thermodynamic analysis
of cascade refrigeration system using ozone friendly refrigerants pair
R507A and R23. R507A is azeotropic mixture composed of HFC
refrigerants R125/R143a (50%/50% wt.). R23 is a single component
HFC refrigerant used as replacement to CFC refrigerant R13 in low
temperature applications. These refrigerants have zero ozone
depletion potential and are non-flammable and as R507A an
azeotropic mixture there is no problem of temperature glide. This
study thermodynamically analyzed R507A-R23 cascade refrigeration
system to optimize the design and operating parameters of the
system. The design and operating parameters include: Condensing,
evaporating, subcooling and superheating temperatures in the high
temperature circuit, temperature difference in the cascade heat
exchanger, Condensing, evaporating, subcooling and superheating
temperatures in the low temperature circuit.