The Cytotoxic Effect of PM 701 and its Fractions on Cell Proliferation of Breast Cancer Cells, McF7

Breast cancer is the most common malignancy in the world among women. Many therapies have been designed to treat this disease. Mamectomy, chemotherapy and radiotherapy are still the main therapies of breast cancer. However, the results were unsatisfactory and still far from the ideal treatment. PM 701is a natural product, has anticancer activity. The bioactive fraction PMF and subfraction PMFK had been isolated from PM701. PM 701 and its fractions were proved to have a cytotoxic properties against different cancer cell lines. This article is directed for the further examination of lyophilized PM701 and its active fractions on the growth of breast cancer cells (MCF-7). PM 701, PMF or PMFK were adding to the cultural medium, where MCF-7 is incubated. PM 701, PMF or PMFK were able to inhibit significantly the proliferation of MCF-7 cells, Moreover these new agents were proved to induce apoptosis of the breast cancer cells; through its direct effect on the nuclei.

Evaluating Telepresence Experience and Game Players' Intention to Purchase Product Advertised in Advergame

In line with changes of consumers modern lifestyle has call for the advertising strategy to change. This research is to find out how game with telepresence and product experience embedded in the computer game to affect users- intention to purchase. Game content developers are urging to consider of placing product message as part of game design strategy that can influence the game player-s intention to purchase. Experiment was carried out on two hundred and fifty undergraduate students who volunteered to participate in the Internet game playing activities. A factor analysis and correlation analysis was performed on items designed to measure telepresence, attitudes toward telepresence, and game player intention to purchase the product advertise in the game that respondents experienced. The results indicated that telepresence consist of interactive experience and product experience. The study also found that product experience is positively related to the game players- intention to purchase. The significance of product experience implies the usefulness of an interactive advertising in the game playing to attract players- intention to purchase the advertised product placed in the creative game design.

Application of the Virtual Reality Modeling Language for Design of Automated Workplaces

Virtual Reality Modelling Language (VRML) is description language, which belongs to a field Window on World virtual reality system. The file, which is in VRML format, can be interpreted by VRML explorer in three-dimensional scene. VRML was created with aim to represent virtual reality on Internet easier. Development of 3D graphic is connected with Silicon Graphic Corporation. VRML 2.0 is the file format for describing interactive 3D scenes and objects. It can be used in collaboration with www, can be used for 3D complex representations creating of scenes, products or VR applications VRML 2.0 enables represent static and animated objects too. Interesting application of VRML is in area of manufacturing systems presentation.

Perceived Constraints on Sport Participation among Young Koreans in Australia

The purpose of this study was to examine a broader range of sport constraints perceived by young Koreans in Australia who may need to adjust to changing behavioral expectations due to the socio-cultural transitions. Regardless of gender, in terms of quantitative findings, the most important participation constraints within the seven categories were resources, access, interpersonal, affective, religious, socio-cultural, and physical in that order. The most important constraining items were a lack of time, access, information, adaptive skills, and parental and family support in that order. Qualitative research found young Korean’s participation constraints among three categories (time, parental control and interpersonal constraints). It is possible that different ethnic groups would be constrained by different factors; however, this is outside the scope of this study.

Some Physico-chemical and Nutritional Properties of Russion Olive (Elaeagnus angustifolia L.) Fruit Grown in Turkey

In this research, several physical and chemical properties and mineral contents of Russion olive (Elaeagnus angustifolia L.) fruit grown in Turkey were determined. In the fruit, length, width, thickness, weight were determined as 2.866cm, 1.880cm, 1.870cm, 2.90g; total soluble solids and colour were determined as 13.14% and S33O60Y99, respectively. In the seed, mean length, width, thickness, and weight were found to be 2.420cm, 0.508cm, 0.503cm, and 0.38g, respectively. In the fruit, 28 minerals (K, P, Ca, Na, Mg, S, Pb, Ba, Ga, As, In, Ti, Fe, Mn, Zn, Cu, Co, B, Cd, Se, Li, Sr, Al, Ni, Ag, V, Cr, Bi) were analyzed and 19 minerals were present at detectable levels. Russion olive fruit was richest in potassium (10296.906ppm), Mg (762.314ppm), P (609.694ppm), Ca (547.647ppm), and Na (222.749ppm).

Certain Conditions for Strongly Starlike and Strongly Convex Functions

In the present paper, we investigate a differential subordination involving multiplier transformation related to a sector in the open unit disk E = {z : |z| < 1}. As special cases to our main result, certain sufficient conditions for strongly starlike and strongly convex functions are obtained.

Knowledge and Skills Requirements for Software Developer Students

It is widely acknowledged that there is a shortage of software developers, not only in South Africa, but also worldwide. Despite reports on a gap between industry needs and software education, the gap has mostly been explored in quantitative studies. This paper reports on the qualitative data of a mixed method study of the perceptions of professional software developers regarding what topics they learned from their formal education and the importance of these topics to their actual work. The analysis suggests that there is a gap between industry’s needs and software development education and the following recommendations are made: 1) Real-life projects must be included in students’ education; 2) Soft skills and business skills must be included in curricula; 3) Universities must keep the curriculum up to date; 4) Software development education must be made accessible to a diverse range of students.

Mathematical Simulation of Acid Concentration Effects during Acid Nitric Leaching of Cobalt from a Mixed Cobalt-Copper Oxide

Cobalt was acid nitric leached from a mixed cobaltcopper oxide with variable acid concentration. Resulting experimental data were used to analyze effects of increase in acid concentration, based on a shrinking core model of the process. The mathematical simulation demonstrated that the time rate of the dissolution mechanism is an increasing function of acid concentration. It was also shown that the magnitude of the acid concentration effect is time dependent and the increase in acid concentration is more effective at earlier stage of the dissolution than at later stage. The remaining process parameters are comprehensively affected by acid concentration and their interaction is synergetic.

Wormhole Attack Detection in Wireless Sensor Networks

The nature of wireless ad hoc and sensor networks make them very attractive to attackers. One of the most popular and serious attacks in wireless ad hoc networks is wormhole attack and most proposed protocols to defend against this attack used positioning devices, synchronized clocks, or directional antennas. This paper analyzes the nature of wormhole attack and existing methods of defending mechanism and then proposes round trip time (RTT) and neighbor numbers based wormhole detection mechanism. The consideration of proposed mechanism is the RTT between two successive nodes and those nodes- neighbor number which is needed to compare those values of other successive nodes. The identification of wormhole attacks is based on the two faces. The first consideration is that the transmission time between two wormhole attack affected nodes is considerable higher than that between two normal neighbor nodes. The second detection mechanism is based on the fact that by introducing new links into the network, the adversary increases the number of neighbors of the nodes within its radius. This system does not require any specific hardware, has good performance and little overhead and also does not consume extra energy. The proposed system is designed in ad hoc on-demand distance vector (AODV) routing protocol and analysis and simulations of the proposed system are performed in network simulator (ns-2).

Analysis of Bit Error Rate Improvement in MFSK Communication Link

Data rate, tolerable bit error rate or frame error rate and range & coverage are the key performance requirement of a communication link. In this paper performance of MFSK link is analyzed in terms of bit error rate, number of errors and total number of data processed. In the communication link model proposed, which is implemented using MATLAB block set, an improvement in BER is observed. Different parameters which effects and enables to keep BER low in M-ary communication system are also identified.

Development of Composite Adsorbent for Waste Water Treatment Using Adsorption and Electrochemical Regeneration

A unique combination of adsorption and electrochemical regeneration with a proprietary adsorbent material called Nyex 100 was introduced at the University of Manchester for waste water treatment applications. Nyex 100 is based on graphite intercalation compound. It is non porous and electrically conducing adsorbent material. This material exhibited very small BET surface area i.e. 2.75 m2g-1, in consequence, small adsorptive capacities for the adsorption of various organic pollutants were obtained. This work aims to develop composite adsorbent material essentially capable of electrochemical regeneration coupled with improved adsorption characteristics. An organic dye, acid violet 17 was used as standard organic pollutant. The developed composite material was successfully electrochemically regenerated using a DC current of 1 A for 60 minutes. Regeneration efficiency was maintained at around 100% for five adsorption-regeneration cycles.

Motion Control of TUAV having Eight Rotors for Enhanced Situational Awareness

This paper focuses on a critical component of the situational awareness (SA), the control of autonomous vertical flight for tactical unmanned aerial vehicle (TUAV). With the SA strategy, we proposed a two stage flight control procedure using two autonomous control subsystems to address the dynamics variation and performance requirement difference in initial and final stages of flight trajectory for a nontrivial nonlinear eight-rotor helicopter model. This control strategy for chosen model of mini-TUAV has been verified by simulation of hovering maneuvers using software package Simulink and demonstrated good performance for fast stabilization of engines in hovering, consequently, fast SA with economy in energy of batteries can be asserted during search-andrescue operations.

An Efficient Segmentation Method Based on Local Entropy Characteristics of Iris Biometrics

An efficient iris segmentation method based on analyzing the local entropy characteristic of the iris image, is proposed in this paper and the strength and weaknesses of the method are analyzed for practical purposes. The method shows special strength in providing designers with an adequate degree of freedom in choosing the proper sections of the iris for their application purposes.

Improving the Elder-s Quality of Life with Smart Television Based Services

The increasing number of senior population gradually causes to demand the use of information and communication technology for their satisfactory lives. This paper presents the development of an integrated TV based system which offers an opportunity to provide value added services to a large number of elderly citizens, and thus helps improve their quality of life. The design philosophy underlying this paper is to fulfill both technological and human aspects. The balance between these two dimensions has been currently stressed as a crucial element for the design of usable systems in real use, particularly to the elderly who have physical and mental decline. As the first step to achieve it, we have identified human and social factors that affect the elder-s quality of life by a literature review, and based on them, build four fundamental services: information, healthcare, learning and social network services. Secondly, the system architecture, employed technologies and the elderly-friendly system design considerations are presented. This reflects technological and human perspectives in terms of the system design. Finally, we describe some scenarios that illustrate the potentiality of the proposed system to improve elderly people-s quality of life.

Controllability of Efficiency of Antiviral Therapy in Hepatitis B Virus Infections

An optimal control problem for a mathematical model of efficiency of antiviral therapy in hepatitis B virus infections is considered. The aim of the study is to control the new viral production, block the new infection cells and maintain the number of uninfected cells in the given range. The optimal controls represent the efficiency of antiviral therapy in inhibiting viral production and preventing new infections. Defining the cost functional, the optimal control problem is converted into the constrained optimization problem and the first order optimality system is derived. For the numerical simulation, we propose the steepest descent algorithm based on the adjoint variable method. A computer program in MATLAB is developed for the numerical simulations.

Attributions by Team Members for Team Outcomes in Finnish Working Life

This study focuses on teamwork in Finnish working life. Through a wide cross-section of teams the study examines the causes to which team members attribute the outcomes of their teams. Qualitative data was collected from 314 respondents. They wrote 616 stories to describe memorable experiences of success and failure in teamwork. The stories revealed 1930 explanations. The findings indicate that both favorable and unfavorable team outcomes are perceived as being caused by the characteristics of team members, relationships between members, team communication, team structure, team goals, team leadership, and external forces. The types represent different attribution levels in the context of organizational teamwork.

A Multi-period Profit Maximization Policy for a Stochastic Demand Inventory System with Upward Substitution

This paper deals with a periodic-review substitutable inventory system for a finite and an infinite number of periods. Here an upward substitution structure, a substitution of a more costly item by a less costly one, is assumed, with two products. At the beginning of each period, a stochastic demand comes for the first item only, which is quality-wise better and hence costlier. Whenever an arriving demand finds zero inventory of this product, a fraction of unsatisfied customers goes for its substitutable second item. An optimal ordering policy has been derived for each period. The results are illustrated with numerical examples. A sensitivity analysis has been done to examine how sensitive the optimal solution and the maximum profit are to the values of the discount factor, when there is a large number of periods.

Thermodynamic Optimization of Turboshaft Engine using Multi-Objective Genetic Algorithm

In this paper multi-objective genetic algorithms are employed for Pareto approach optimization of ideal Turboshaft engines. In the multi-objective optimization a number of conflicting objective functions are to be optimized simultaneously. The important objective functions that have been considered for optimization are specific thrust (F/m& 0), specific fuel consumption ( P S ), output shaft power 0 (& /&) shaft W m and overall efficiency( ) O η . These objectives are usually conflicting with each other. The design variables consist of thermodynamic parameters (compressor pressure ratio, turbine temperature ratio and Mach number). At the first stage single objective optimization has been investigated and the method of NSGA-II has been used for multiobjective optimization. Optimization procedures are performed for two and four objective functions and the results are compared for ideal Turboshaft engine. In order to investigate the optimal thermodynamic behavior of two objectives, different set, each including two objectives of output parameters, are considered individually. For each set Pareto front are depicted. The sets of selected decision variables based on this Pareto front, will cause the best possible combination of corresponding objective functions. There is no superiority for the points on the Pareto front figure, but they are superior to any other point. In the case of four objective optimization the results are given in tables.

Abai Kunanbayev's Role in Enrichment of the Kazakh Language

Abai Kunanbayev is famous for being enlightener, composer, interpreter, social agent, philosopher, reformer, who wanted to enrich Kazakh literature by emergence with Russian and European culture, and also as a founder of Kazakh written literary language. Abai Kunanbayev was born in 1845 in East Kazakhstan area and passed away in 1904 in his hometown. His oeuvre absorbed and reflected all changes in the life of Kazakh society of the second half of XIX century. Because ХІХ century, especially its second half, was an important transition period for Kazakhstan, which radically changed traditional way of Kazakh society and predetermined further development in consequence of activation of Russian colonial policy and approval of commodity-money relations in Steppe Land.Abai Kunanbayev, besides Arabic and Persian common words and loanwords from Quran in his words of edification, had used a lot of words of Arabic, Persian, Latin, Russian, Nogai, Shaghatai, Polish, Greek, Turkish, which are used in the Kazakh language.

Six Sigma Process and its Impact on the Organizational Productivity

The six sigma method is a project-driven management approach to improve the organization-s products, services, and processes by continually reducing defects in the organization. Understanding the key features, obstacles, and shortcomings of the six sigma method allows organizations to better support their strategic directions, and increasing needs for coaching, mentoring, and training. It also provides opportunities to better implement six sigma projects. The purpose of this paper is the survey of six sigma process and its impact on the organizational productivity. So I have studied key concepts , problem solving process of six sigmaas well as the survey of important fields such as: DMAIC, six sigma and productivity applied programme, and other advantages of six sigma. In the end of this paper, present research conclusions. (direct and positive relation between six sigma and productivity)