Abstract: Designing modern machine tools is a complex task. A
simulation tool to aid the design work, a virtual machine, has
therefore been developed in earlier work. The virtual machine
considers the interaction between the mechanics of the machine
(including structural flexibility) and the control system. This paper
exemplifies the usefulness of the virtual machine as a tool for product
development. An optimisation study is conducted aiming at
improving the existing design of a machine tool regarding weight and
manufacturing accuracy at maintained manufacturing speed. The
problem can be categorised as constrained multidisciplinary multiobjective
multivariable optimisation. Parameters of the control and
geometric quantities of the machine are used as design variables. This
results in a mix of continuous and discrete variables and an
optimisation approach using a genetic algorithm is therefore
deployed. The accuracy objective is evaluated according to
international standards. The complete systems model shows nondeterministic
behaviour. A strategy to handle this based on statistical
analysis is suggested. The weight of the main moving parts is reduced
by more than 30 per cent and the manufacturing accuracy is
improvement by more than 60 per cent compared to the original
design, with no reduction in manufacturing speed. It is also shown
that interaction effects exist between the mechanics and the control,
i.e. this improvement would most likely not been possible with a
conventional sequential design approach within the same time, cost
and general resource frame. This indicates the potential of the virtual
machine concept for contributing to improved efficiency of both
complex products and the development process for such products.
Companies incorporating such advanced simulation tools in their
product development could thus improve its own competitiveness as
well as contribute to improved resource efficiency of society at large.
Abstract: Biochemical investigations were carried out to assess
the effect of different exposure regimes of Kazakhstan crude oil
(KCO) on hepatic antioxidant defense system in albino rats.
Contaminants were delivered under two different dosing regimes,
with all treatments receiving the same total contaminant load by the
end of the exposure period. Rats in regime A injected with KCO
once at a dose of 6 ml/kg bw while in regime B injected multiply at a
dose of 1.5 ml/kg bw on day 1, 3, 5 and 8. Antioxidant biomarkers
were measured in hepatic tissue after 1, 3, 5 and 8 days. Significant
induction was observed in serum aminotransferases (ALT, AST)
(p
Abstract: MicroRNAs (miRNAs) are a class of non-coding
RNAs that hybridize to mRNAs and induce either translation
repression or mRNA cleavage. Recently, it has been reported that
miRNAs could possibly play an important role in human diseases. By
integrating miRNA target genes, cancer genes, miRNA and mRNA
expression profiles information, a database is developed to link
miRNAs to cancer target genes. The database provides experimentally
verified human miRNA target genes information, including oncogenes
and tumor suppressor genes. In addition, fragile sites information for
miRNAs, and the strength of the correlation of miRNA and its target
mRNA expression level for nine tissue types are computed, which
serve as an indicator for suggesting miRNAs could play a role in
human cancer. The database is freely accessible at
http://ppi.bioinfo.asia.edu.tw/mirna_target/index.html.
Abstract: The purpose of this study was to survey the effect of
organizational communication system on the conflict in physical
education offices of Isfahan province. The research methodology of
this research was a descriptive study. All employees working in
physical education offices of Isfahan province were included in the
sample for this study (N= 236). Researcher made questionnaire and
demographic questionnaire were used as investigation instruments.
Based on the result of chi square test, there is significant difference
between organizational communication system and interpersonal
conflict. The most of participants evaluate communication in an
informal way and pointed out that the communication channels were
not open. Based on the result of binomial test, interpersonal conflict
exists in physical education offices of Isfahan.
Abstract: Previous studies have indicated that one of the most
critical failure reasons of enterprise systems is the lack of knowledge
sharing and utilization across organizations. As a consequence, many
information systems researchers have paid attention to examining the
effect of absorptive capacity closely associated with knowledge
sharing and transferring on IS usage performance. A lack of
communications and interactions due to a lack of organizational
citizenship behavior might lead to weak absorptive capacity and thus
negatively influence knowledge sharing across organizations. In this
study, a theoretical model which delves into the relationship between
usage performance of enterprise systems and its determinants was
established.
Abstract: Based on the standard finite element method, a new
finite element method which is known as nonlocal finite element
method (NL-FEM) is numerically implemented in this article to
study the nonlocal effects for solving 1D nonlocal elastic problem.
An Eringen-type nonlocal elastic model is considered. In this model,
the constitutive stress-strain law is expressed interms of integral
equation which governs the nonlocal material behavior. The new
NL-FEM is adopted in such a way that the postulated nonlocal elastic
behavior of material is captured by a finite element endowed with a
set of (cross-stiffness) element itself by the other elements in mesh.
An example with their analytical solutions and the relevant numerical
findings for various load and boundary conditions are presented and
discussed in details. It is observed from the numerical solutions that
the torsional deformation angle decreases with increasing nonlocal
nanoscale parameter. It is also noted that the analytical solution fails
to capture the nonlocal effect in some cases where numerical
solutions handle those situation effectively which prove the
reliability and effectiveness of numerical techniques.
Abstract: Artemia is one of the most conspicuous invertebrates
associated with aquaculture. It can be considered as a model
organism, offering numerous advantages for comprehensive and
multidisciplinary studies using morphologic or molecular methods.
Since DNA extraction is an important step of any molecular
experiment, a new and a rapid method of DNA extraction from adult
Artemia was described in this study. Besides, the efficiency of this
technique was compared with two widely used alternative techniques,
namely Chelex® 100 resin and SDS-chloroform methods. Data
analysis revealed that the new method is the easiest and the most cost
effective method among the other methods which allows a quick and
efficient extraction of DNA from the adult animal.
Abstract: In the present paper, we-ll explore how social media tools provide an opportunity for new developments of the e-Learning in the context of managing personal knowledge. There will be a discussion how social media tools provide a possibility for helping knowledge workersand students to gather, organize and manage their personal information as a part of the e-learning process. At the centre of this social software driven approach to e-learning environments are the challenges of personalization and collaboration. We-ll share concepts of how organizations are using social media for e-Learning and believe that integration of these tools into traditional e-Learning is probably not a choice, but inevitability. Students- Survey of use of web technologies and social networking tools is presented. Newly developed framework for semantic blogging capable of organizing results relevant to user requirements is implemented at Varna Free University (VFU) to provide more effective navigation and search.
Abstract: Dengue, a disease found in most tropical and
subtropical areas of the world. It has become the most common
arboviral disease of humans. This disease is caused by any of four
serotypes of dengue virus (DEN1-DEN4). In many endemic
countries, the average age of getting dengue infection is shifting
upwards, dengue in pregnancy and infancy are likely to be
encountered more frequently. The dynamics of the disease is studied
by a compartmental model involving ordinary differential equations
for the pregnant, infant human and the vector populations. The
stability of each equilibrium point is given. The epidemic dynamic is
discussed. Moreover, the numerical results are shown for difference
values of dengue antibody.
Abstract: Calcium is very important for communication among
the neurons. It is vital in a number of cell processes such as secretion,
cell movement, cell differentiation. To reduce the system of reactiondiffusion
equations of [Ca2+] into a single equation, two theories
have been proposed one is excess buffer approximation (EBA) other
is rapid buffer approximation (RBA). The RBA is more realistic than
the EBA as it considers both the mobile and stationary endogenous
buffers. It is valid near the mouth of the channel. In this work we have
studied the effects of different types of buffers on calcium diffusion
under RBA. The novel thing studied is the effect of sodium ions on
calcium diffusion. The model has been made realistic by considering
factors such as variable [Ca2+], [Na+] sources, sodium-calcium
exchange protein(NCX), Sarcolemmal Calcium ATPase pump. The
proposed mathematical leads to a system of partial differential equations
which has been solved numerically to study the relationships
between different parameters such as buffer concentration, buffer
disassociation rate, calcium permeability. We have used Forward
Time Centred Space (FTCS) approach to solve the system of partial
differential equations.
Abstract: Educating effective architect designers is an important
goal of architectural education. But what contributes to students-
performance, and to critical and creative thinking in architectural
design education? Besides teaching architecture students how to
understand logical arguments, eliminate the inadequate solutions and
focus on the correct ones, it is also crucial to teach students how to
focus on exploring ideas and the alternative solutions and seeking for
other right answers rather than one. This paper focuses on the
enhancing architectural design education and may provide
implications for enhancing teaching design.
Abstract: Security is an interesting and significance issue for
popular virtual platforms, such as virtualization cluster and cloud
platforms. Virtualization is the powerful technology for cloud
computing services, there are a lot of benefits by using virtual machine
tools which be called hypervisors, such as it can quickly deploy all
kinds of virtual Operating Systems in single platform, able to control
all virtual system resources effectively, cost down for system platform
deployment, ability of customization, high elasticity and high
reliability. However, some important security problems need to take
care and resolved in virtual platforms that include terrible viruses, evil
programs, illegal operations and intrusion behavior. In this paper, we
present useful Intrusion Detection Mechanism (IDM) software that not
only can auto to analyze all system-s operations with the accounting
journal database, but also is able to monitor the system-s state for
virtual platforms.
Abstract: The present research was focused to investigate the
role of investment in the course of economic growth with reference to
Pakistan. The study analyzed the role of the public and private
investment and impact of the political and macroeconomic
uncertainty on economic growth of Pakistan by using the vector
autoregressive approach (VAR). In long-run both public and private
investment showed a positive impact on economic growth but the
growth was largely driven by private investment as compared to
public investment. Government consumption expenditure, economic
uncertainty and political instability hampered the economic growth of
Pakistan. In short-run the private investment positively influences the
growth but there was negative and insignificant effect of the public
investment and government consumption expenditure on the growth.
There was a positive relationship found between economic
uncertainty (proxy for inflation) and GDP in short run.
Abstract: A feeding trial was conducted to investigate the effect
of periodically use of garlic on performance and carcass
characteristics in broiler chickens. 240 1-day-old Ross broiler chicks
randomly allocated into the 10 dietary treatments (A, B, C, D, E, F,
G, H, I and J) for 6 wk. Treatment A or control group, received basal
diet (based on standards of Ross management guidelines) without
supplementation of garlic powder while B, C and D dietary
treatments were basal diet supplemented with 0.5, 1 and 3% garlic
powder, respectively for the whole time of experiment (6 weeks).
Birds in group E, F and G were fed control diet supplemented with
0.5, 1 and 3% garlic powder, respectively just in their starter diet (0-
21d). Birds in three other treatments (H, I and J) received control diet
for the first 21 days and 0.5, 1 and 3% of garlic powder was added to
their finisher diets, respectively. 1 and 3% supplemented groups in
finisher period had better performance as compared with other
groups. Since present study conducted in optimum and antiseptic
conditions, it seems that better or more responses could be expected
in performance if the raising conditions would not be healthy.
Abstract: The objective of this work was to examine the changes
in non destructive properties caused by carbonation of CEM II
mortar. Samples of CEM II mortar were prepared and subjected to
accelerated carbonation at 20°C, 65% relative humidity and 20% CO2
concentration. We examined the evolutions of the gas permeability,
the thermal conductivity, the thermal diffusivity, the volume of the
solid phase by helium pycnometry, the longitudinal and transverse
ultrasonic velocities. The principal contribution of this work is that,
apart of the gas permeability, changes in other non destructive
properties have never been studied during the carbonation of cement
materials. These properties are important in predicting/measuring the
durability of reinforced concrete in CO2 environment. The
carbonation depth and the porosity accessible to water were also
reported in order to explain comprehensively the changes in non
destructive parameters.
Abstract: It is an important problem to compute the geodesics on
a surface in many fields. To find the geodesics in practice, however,
the traditional discrete algorithms or numerical approaches can only
find a list of discrete points. The first author proposed in 2010 a new,
elegant and accurate method, the geodesic-like method, for
approximating geodesics on a regular surface. This paper will present
by use of this method a computation of the Bezier geodesic-like curves
on spheres.
Abstract: It is not a secret that, IT management has become
more and more and integrated part of almost all organizations. IT
managers posses an enormous amount of knowledge within both
organizational knowledge and general IT knowledge. This article
investigates how IT managers keep themselves updated on IT
knowledge in general and looks into how much time IT managers
spend on weekly basis searching the net for new or problem solving
IT knowledge. The theory used in this paper is used to investigate the
current role of IT managers and what issues they are facing.
Furthermore a research is conducted where 7 IT managers in medium
sized and large Danish companies are interviewed to add further
focus on the role of the IT manager and to focus on how they keep
themselves updated. Beside finding substantial need for more
research, IT managers – generalists or specialists – only have limited
knowledge resources at hand in updating their own knowledge –
leaving much initiative to vendors.
Abstract: Real options theory suggests that managerial flexibility embedded within irreversible investments can account for a significant value in project valuation. Although the argument has become the dominant focus of capital investment theory over decades, yet recent survey literature in capital budgeting indicates that corporate practitioners still do not explicitly apply real options in investment decisions. In this paper, we explore how real options decision criteria can be transformed into equivalent capital budgeting criteria under the consideration of uncertainty, assuming that underlying stochastic process follows a geometric Brownian motion (GBM), a mixed diffusion-jump (MX), or a mean-reverting process (MR). These equivalent valuation techniques can be readily decomposed into conventional investment rules and “option impacts", the latter of which describe the impacts on optimal investment rules with the option value considered. Based on numerical analysis and Monte Carlo simulation, three major findings are derived. First, it is shown that real options could be successfully integrated into the mindset of conventional capital budgeting. Second, the inclusion of option impacts tends to delay investment. It is indicated that the delay effect is the most significant under a GBM process and the least significant under a MR process. Third, it is optimal to adopt the new capital budgeting criteria in investment decision-making and adopting a suboptimal investment rule without considering real options could lead to a substantial loss in value.
Abstract: This paper presents an exploration into the structure of the corporate governance network and interlocking directorates in the Czech Republic. First a literature overview and a basic terminology of the network theory is presented. Further in the text, statistics and other calculations relevant to corporate governance networks are presented. For this purpose an empirical data set consisting of 2 906 joint stock companies in the Czech Republic was examined. Industries with the highest average number of interlocks per company were healthcare, and energy and utilities. There is no observable link between the financial performance of the company and the number of its interlocks. Also interlocks with financial companies are very rare.
Abstract: Radio frequency identification (RFID) applications have grown rapidly in many industries, especially in indoor location identification. The advantage of using received signal strength indicator (RSSI) values as an indoor location measurement method is a cost-effective approach without installing extra hardware. Because the accuracy of many positioning schemes using RSSI values is limited by interference factors and the environment, thus it is challenging to use RFID location techniques based on integrating positioning algorithm design. This study proposes the location estimation approach and analyzes a scheme relying on RSSI values to minimize location errors. In addition, this paper examines different factors that affect location accuracy by integrating the backpropagation neural network (BPN) with the LANDMARC algorithm in a training phase and an online phase. First, the training phase computes coordinates obtained from the LANDMARC algorithm, which uses RSSI values and the real coordinates of reference tags as training data for constructing an appropriate BPN architecture and training length. Second, in the online phase, the LANDMARC algorithm calculates the coordinates of tracking tags, which are then used as BPN inputs to obtain location estimates. The results show that the proposed scheme can estimate locations more accurately compared to LANDMARC without extra devices.