Abstract: Herpes zoster is a disease that manifests as a dermatological condition. The characteristic of this disease is an irritating skin rash with blisters. This is often limited to one side of body. From the data of Herpes zoster cases in Thailand, we found that age structure effects to the transmission of this disease. In this study, we construct the age structural model of Herpes zoster in Thailand. The local stability analysis of this model is given. The numerical solutions are shown to confirm the analytical results.
Abstract: We used mathematical model to study the
transmission of dengue disease. The model is developed in which
the human population is separated into two populations, pregnant and
non-pregnant humans. The dynamical analysis method is used for
analyzing this modified model. Two equilibrium states are found and
the conditions for stability of theses two equilibrium states are
established. Numerical results are shown for each equilibrium state.
The basic reproduction numbers are found and they are compared by
using numerical simulations.
Abstract: Malaria is a serious, acute and chronic relapsing
infection to humans. It is characterized by periodic attacks of chills,
fever, nausea, vomiting, back pain, increased sweating anemia,
splenomegaly (enlargement of the spleen) and often-fatal
complications.The malaria disease is caused by the multiplication of
protozoa parasite of the genus Plasmodium. Malaria in humans is due
to 4 types of malaria parasites such that Plasmodium falciparum,
Plasmodium vivax, Plasmodium malariae and Plasmodium ovale.
P.vivax malaria differs from P. falciparum malaria in that a person
suffering from P. vivax malaria can experience relapses of the
disease. Between the relapses, the malaria parasite will remain
dormant in the liver of the patient, leading to the patient being
classified as being in the dormant class. A mathematical model for
the transmission of P. vivax is developed in which the human
population is divided into four classes, the susceptible, the infected,
the dormant and the recovered. In this paper, we formulate the
dynamical model of P. vivax malaria to see the distribution of this
disease at the district level.
Abstract: Malaria is transmitted to the human by biting of
infected Anopheles mosquitoes. This disease is a serious, acute and
chronic relapsing infection to humans. Fever, nausea, vomiting, back
pain, increased sweating anemia and splenomegaly (enlargement of
the spleen) are the symptoms of the patients who infected with this
disease. It is caused by the multiplication of protozoa parasite of the
genus Plasmodium. Plasmodium falciparum, Plasmodium vivax,
Plasmodium malariae and Plasmodium ovale are the four types of
Plasmodium malaria. A mathematical model for the transmission of
Plasmodium Malaria is developed in which the human and vector
population are divided into two classes, the susceptible and the
infectious classes. In this paper, we formulate the dynamical model
of Plasmodium falciparum and Plasmodium vivax malaria. The
standard dynamical analysis is used for analyzing the behavior for
the transmission of this disease. The Threshold condition is found
and numerical results are shown to confirm the analytical results.
Abstract: Leptospirosis occurs worldwide (except the
poles of the earth), urban and rural areas, developed and
developing countries, especially in Thailand. It can be
transmitted to the human by rats through direct and indirect
ways. Human can be infected by either touching the infected rats
or contacting with water, soil containing urine from the infected
rats through skin, eyes and nose. The data of the people who
are infected with this disease indicates that most of the
patients are adults. The transmission of this disease is studied
through mathematical model. The population is separated into human
and rat. The human is divided into two classes, namely juvenile
and adult. The model equation is constructed for each class. The
standard dynamical modeling method is then used for
analyzing the behaviours of solutions. In addition, the
conditions of the parameters for the disease free and endemic
states are obtained. Numerical solutions are shown to support the
theoretical predictions. The results of this study guide the way to
decrease the disease outbreak.
Abstract: One of the important tropical diseases is
Chikunkunya. This disease is transmitted between the human by the
insect-borne virus, of the genus Alphavirus. It occurs in Africa, Asia
and the Indian subcontinent. In Thailand, the incidences due to this
disease are increasing every year. In this study, the transmission of
this disease is studied through dynamical model analysis.
Abstract: The Swine flu outbreak in humans is due to a new
strain of influenza A virus subtype H1N1 that derives in part from
human influenza, avian influenza, and two separated strains of swine
influenza. It can be transmitted from human to human. A
mathematical model for the transmission of Swine flu is developed in
which the human populations are divided into two classes, the risk
and non-risk human classes. Each class is separated into susceptible,
exposed, infectious, quarantine and recovered sub-classes. In this
paper, we formulate the dynamical model of Swine flu transmission
and the repetitive contacts between the people are also considered.
We analyze the behavior for the transmission of this disease. The
Threshold condition of this disease is found and numerical results are
shown to confirm our theoretical predictions.
Abstract: Dengue, a disease found in most tropical and
subtropical areas of the world. It has become the most common
arboviral disease of humans. This disease is caused by any of four
serotypes of dengue virus (DEN1-DEN4). In many endemic
countries, the average age of getting dengue infection is shifting
upwards, dengue in pregnancy and infancy are likely to be
encountered more frequently. The dynamics of the disease is studied
by a compartmental model involving ordinary differential equations
for the pregnant, infant human and the vector populations. The
stability of each equilibrium point is given. The epidemic dynamic is
discussed. Moreover, the numerical results are shown for difference
values of dengue antibody.
Abstract: Dengue virus is transmitted from person to person
through the biting of infected Aedes Aegypti mosquitoes. DEN-1,
DEN-2, DEN-3 and DEN-4 are four serotypes of this virus. Infection
with one of these four serotypes apparently produces permanent
immunity to it, but only temporary cross immunity to the others. The
length of time during incubation of dengue virus in human and
mosquito are considered in this study. The dengue patients are
classified into infected and infectious classes. The infectious human
can transmit dengue virus to susceptible mosquitoes but infected
human can not. The transmission model of this disease is formulated.
The human population is divided into susceptible, infected, infectious
and recovered classes. The mosquito population is separated into
susceptible, infected and infectious classes. Only infectious
mosquitoes can transmit dengue virus to the susceptible human. We
analyze this model by using dynamical analysis method. The
threshold condition is discussed to reduce the outbreak of this
disease.
Abstract: A new strain of Type A influenza virus can cause the
transmission of H1N1 virus. This virus can spread between the
people by coughing and sneezing. Because the people are always
movement, so this virus can be easily spread. In this study, we
construct the dynamical network model of H1N1 virus by separating
the human into five groups; susceptible, exposed, infectious,
quarantine and recovered groups. The movement of people between
houses (local level) is considered. The behaviors of solutions to our
dynamical model are shown for the different parameters.
Abstract: Mathematical models can be used to describe the
transmission of disease. Dengue disease is the most significant
mosquito-borne viral disease of human. It now a leading cause of
childhood deaths and hospitalizations in many countries. Variations
in environmental conditions, especially seasonal climatic parameters,
effect to the transmission of dengue viruses the dengue viruses and
their principal mosquito vector, Aedes aegypti. A transmission model
for dengue disease is discussed in this paper. We assume that the
human and vector populations are constant. We showed that the local
stability is completely determined by the threshold parameter, 0 B . If
0 B is less than one, the disease free equilibrium state is stable. If
0 B is more than one, a unique endemic equilibrium state exists and
is stable. The numerical results are shown for the different values of
the transmission probability from vector to human populations.
Abstract: Plasmodium vivax malaria differs from P. falciparum malaria in that a person suffering from P. vivax infection can suffer relapses of the disease. This is due the parasite being able to remain dormant in the liver of the patients where it is able to re-infect the patient after a passage of time. During this stage, the patient is classified as being in the dormant class. The model to describe the transmission of P. vivax malaria consists of a human population divided into four classes, the susceptible, the infected, the dormant and the recovered. The effect of a time delay on the transmission of this disease is studied. The time delay is the period in which the P. vivax parasite develops inside the mosquito (vector) before the vector becomes infectious (i.e., pass on the infection). We analyze our model by using standard dynamic modeling method. Two stable equilibrium states, a disease free state E0 and an endemic state E1, are found to be possible. It is found that the E0 state is stable when a newly defined basic reproduction number G is less than one. If G is greater than one the endemic state E1 is stable. The conditions for the endemic equilibrium state E1 to be a stable spiral node are established. For realistic values of the parameters in the model, it is found that solutions in phase space are trajectories spiraling into the endemic state. It is shown that the limit cycle and chaotic behaviors can only be achieved with unrealistic parameter values.