Abstract: An optimal control problem for a mathematical model of efficiency of antiviral therapy in hepatitis B virus infections is considered. The aim of the study is to control the new viral production, block the new infection cells and maintain the number of uninfected cells in the given range. The optimal controls represent the efficiency of antiviral therapy in inhibiting viral production and preventing new infections. Defining the cost functional, the optimal control problem is converted into the constrained optimization problem and the first order optimality system is derived. For the numerical simulation, we propose the steepest descent algorithm based on the adjoint variable method. A computer program in MATLAB is developed for the numerical simulations.
Abstract: In this paper multi-objective genetic algorithms are
employed for Pareto approach optimization of ideal Turboshaft
engines. In the multi-objective optimization a number of conflicting
objective functions are to be optimized simultaneously. The
important objective functions that have been considered for
optimization are specific thrust (F/m& 0), specific fuel consumption
( P S ), output shaft power 0 (& /&) shaft W m and overall efficiency( ) O
η .
These objectives are usually conflicting with each other. The design
variables consist of thermodynamic parameters (compressor pressure
ratio, turbine temperature ratio and Mach number).
At the first stage single objective optimization has been
investigated and the method of NSGA-II has been used for multiobjective
optimization. Optimization procedures are performed for
two and four objective functions and the results are compared for
ideal Turboshaft engine. In order to investigate the optimal
thermodynamic behavior of two objectives, different set, each
including two objectives of output parameters, are considered
individually. For each set Pareto front are depicted. The sets of
selected decision variables based on this Pareto front, will cause the
best possible combination of corresponding objective functions.
There is no superiority for the points on the Pareto front figure,
but they are superior to any other point. In the case of four objective
optimization the results are given in tables.
Abstract: Today, Higher Education in a global scope is subordinated to the greater institutional controls through the policies of the Quality of Education. These include processes of over evaluation of all the academic activities: students- and professors- performance, educational logistics, managerial standards for the administration of institutions of higher education, as well as the establishment of the imaginaries of excellence and prestige as the foundations on which universities of the XXI century will focus their present and future goals and interests. But at the same time higher education systems worldwide are facing the most profound crisis of sense and meaning and attending enormous mutations in their identity. Based in a qualitative research approach, this paper shows the social configurations that the scholars at the Universities in Mexico build around the discourse of the Quality of Education, and how these policies put in risk the social recognition of these individuals.
Abstract: Despite many success stories of manufacturing safety, many organizations are still reluctant, perceiving it as cost increasing and time consuming. The clear contributor may be due to the use of lagging indicators rather than leading indicator measures. The study therefore proposes a combinatorial model for determining the best safety strategy. A combination theory and cost benefit analysis was employed to develop a monetary saving / loss function in terms value of preventions and cost of prevention strategy. Documentations, interviews and structured questionnaire were employed to collect information on Before-And-After safety programme records from a Tobacco company between periods of 1993-2001(for pre-safety) and 2002-2008 (safety period) for the model application. Three combinatorial alternatives A, B, C were obtained resulting into 4, 6 and 4 strategies respectively with PPE and Training being predominant. A total of 728 accidents were recorded for a 9 year period of pre-safety programme and 163 accidents were recorded for 7 years period of safety programme. Six preventions activities (alternative B) yielded the best results. However, all the years of operation experienced except year 2004. The study provides a leading resources for planning successful safety programme
Abstract: In the last decades to supply the various and different
demands of clients, a lot of manufacturers trend to use the mixedmodel
assembly line (MMAL) in their production lines, since this
policy make possible to assemble various and different models of the
equivalent goods on the same line with the MTO approach.
In this article, we determine the sequence of (MMAL) line, with
applying the kitting approach and planning of rest time for general
workers to reduce the wastages, increase the workers effectiveness
and apply the sector of lean production approach.
This Multi-objective sequencing problem solved in small size with
GAMS22.2 and PSO meta heuristic in 10 test problems and compare
their results together and conclude that their results are very similar
together, next we determine the important factors in computing the
cost, which improving them cost reduced. Since this problem, is NPhard
in large size, we use the particle swarm optimization (PSO)
meta-heuristic for solving it. In large size we define some test
problems to survey it-s performance and determine the important
factors in calculating the cost, that by change or improved them
production in minimum cost will be possible.
Abstract: In this paper, we represent protein structure by using
graph. A protein structure database will become a graph database.
Each graph is represented by a spectral vector. We use Jacobi
rotation algorithm to calculate the eigenvalues of the normalized
Laplacian representation of adjacency matrix of graph. To measure
the similarity between two graphs, we calculate the Euclidean
distance between two graph spectral vectors. To cluster the graphs,
we use M-tree with the Euclidean distance to cluster spectral vectors.
Besides, M-tree can be used for graph searching in graph database.
Our proposal method was tested with graph database of 100 graphs
representing 100 protein structures downloaded from Protein Data
Bank (PDB) and we compare the result with the SCOP hierarchical
structure.
Abstract: Planning capacities when regenerating complex investment goods involves particular challenges in that the planning is subject to a large degree of uncertainty regarding load information. Using information fusion – by applying Bayesian Networks – a method is being developed for forecasting the anticipated expenditures (human labor, tool and machinery utilization, time etc.) for regenerating a good. The generated forecasts then later serve as a tool for planning capacities and ensure a greater stability in the planning processes.
Abstract: Web applications have become very complex and
crucial, especially when combined with areas such as CRM
(Customer Relationship Management) and BPR (Business Process
Reengineering), the scientific community has focused attention to
Web applications design, development, analysis, and testing, by
studying and proposing methodologies and tools. This paper
proposes an approach to automatic multi-dimensional concern
mining for Web Applications, based on concepts analysis, impact
analysis, and token-based concern identification. This approach lets
the user to analyse and traverse Web software relevant to a particular
concern (concept, goal, purpose, etc.) via multi-dimensional
separation of concerns, to document, understand and test Web
applications. This technique was developed in the context of WAAT
(Web Applications Analysis and Testing) project. A semi-automatic
tool to support this technique is currently under development.
Abstract: This study examined a habitat-suitability assessment method namely the Ecological Niche Factor Analysis (ENFA). A virtual species was created and then dispatched in a geographic information system model of a real landscape in three historic scenarios: (1) spreading, (2) equilibrium, and (3) overabundance. In each scenario, the virtual species was sampled and these simulated data sets were used as inputs for the ENFA to reconstruct the habitat suitability model. The 'equilibrium' scenario gives the highest quantity and quality among three scenarios. ENFA was sensitive to the distribution scenarios but not sensitive to sample sizes. The use of a virtual species proved to be a very efficient method, allowing one to fully control the quality of the input data as well as to accurately evaluate the predictive power of the analyses.
Abstract: Mammographic images and data analysis to
facilitate modelling or computer aided diagnostic (CAD) software development should best be done using a common database that can handle various mammographic image file
formats and relate these to other patient information.
This would optimize the use of the data as both primary
reporting and enhanced information extraction of research data could be performed from the single dataset. One desired
improvement is the integration of DICOM file header information into the database, as an efficient and reliable source of supplementary patient information intrinsically
available in the images.
The purpose of this paper was to design a suitable database to link and integrate different types of image files and gather common information that can be further used for research
purposes. An interface was developed for accessing, adding,
updating, modifying and extracting data from the common
database, enhancing the future possible application of the data in CAD processing.
Technically, future developments envisaged include the creation of an advanced search function to selects image files
based on descriptor combinations. Results can be further used for specific CAD processing and other research. Design of a
user friendly configuration utility for importing of the required fields from the DICOM files must be done.
Abstract: Noise level has critical effects on the diagnostic
performance of signal-averaged electrocardiogram (SAECG), because
the true starting and end points of QRS complex would be masked by
the residual noise and sensitive to the noise level. Several studies and
commercial machines have used a fixed number of heart beats
(typically between 200 to 600 beats) or set a predefined noise level
(typically between 0.3 to 1.0 μV) in each X, Y and Z lead to perform
SAECG analysis. However different criteria or methods used to
perform SAECG would cause the discrepancies of the noise levels
among study subjects. According to the recommendations of 1991
ESC, AHA and ACC Task Force Consensus Document for the use of
SAECG, the determinations of onset and offset are related closely to
the mean and standard deviation of noise sample. Hence this study
would try to perform SAECG using consistent root-mean-square
(RMS) noise levels among study subjects and analyze the noise level
effects on SAECG. This study would also evaluate the differences
between normal subjects and chronic renal failure (CRF) patients in
the time-domain SAECG parameters.
The study subjects were composed of 50 normal Taiwanese and 20
CRF patients. During the signal-averaged processing, different RMS
noise levels were adjusted to evaluate their effects on three time
domain parameters (1) filtered total QRS duration (fQRSD), (2) RMS
voltage of the last QRS 40 ms (RMS40), and (3) duration of the low
amplitude signals below 40 μV (LAS40). The study results
demonstrated that the reduction of RMS noise level can increase
fQRSD and LAS40 and decrease the RMS40, and can further increase
the differences of fQRSD and RMS40 between normal subjects and
CRF patients. The SAECG may also become abnormal due to the
reduction of RMS noise level. In conclusion, it is essential to establish
diagnostic criteria of SAECG using consistent RMS noise levels for
the reduction of the noise level effects.
Abstract: Canola is a specific edible type of rapeseed, developed
in the 1970s, which contains about 40 percent oil. This research was
carried out to determine the yield and some quality characteristics of
some winter canola cultivars during the 2010-2011 vegetation period
in Central Anatolia of Turkey. In this research; Oase, Dante,
Californium, Excalibur, Elvis, ES Hydromel, Licord, Orkan, Vectra,
Nelson, Champlain and NK Petrol winter canola varieties were used
as material. The field experiment was set up in a “Randomized
Complete Block Design” with three replications on 21 September
2010. In this research; seed yield, oil content, protein content, oil
yield and protein yield were examined.
As a result of this research; seed yield, oil content, oil yield and
protein yield (except protein content) were significant differences
between the cultivars. The highest seed yield (6348 kg ha-1) was
obtained from the NK Petrol, while the lowest seed yield (3949 kg
ha-1) was determined from the Champlain cultivar was obtained. The
highest oil content (46.73%) was observed from Oase and the lowest
value was obtained from Vectra (41.87%) cultivar. The highest oil
yield (2950 kg ha-1) was determined from NK Petrol while the least
value (1681 kg ha-1) was determined from Champlain cultivar. The
highest protein yield (1539.3 kg ha-1) was obtained from NK Petrol
and the lowest protein yield (976.5 kg ha-1) was obtained from
Champlain cultivar.
The main purpose of the cultivation of oil crops, to increase the
yield of oil per unit area. According the result of this research, NK
Petrol cultivar which ranks first with regard to both seed yield and oil
yield between cultivars as the most suitable winter canola cultivar of
local conditions.
Abstract: The new programming technologies allow for the
creation of components which can be automatically or manually
assembled to reach a new experience in knowledge understanding
and mastering or in getting skills for a specific knowledge area. The
project proposes an interactive framework that permits the creation,
combination and utilization of components that are specific to
mathematical training in high schools.
The main framework-s objectives are:
• authoring lessons by the teacher or the students; all they need
are simple operating skills for Equation Editor (or something
similar, or Latex); the rest are just drag & drop operations,
inserting data into a grid, or navigating through menus
• allowing sonorous presentations of mathematical texts and
solving hints (easier understood by the students)
• offering graphical representations of a mathematical function
edited in Equation
• storing of learning objects in a database
• storing of predefined lessons (efficient for expressions and
commands, the rest being calculations; allows a high
compression)
• viewing and/or modifying predefined lessons, according to the
curricula
The whole thing is focused on a mathematical expressions minicompiler,
storing the code that will be later used for different
purposes (tables, graphics, and optimisations).
Programming technologies used. A Visual C# .NET
implementation is proposed. New and innovative digital learning
objects for mathematics will be developed; they are capable to
interpret, contextualize and react depending on the architecture
where they are assembled.
Abstract: Religion revival including Islam in Kazakhstan represents reaction, first of all on internal social and political change, events after disintegration of the USSR. Process of revival of Kazakhstan Islam was accompanied as positive, so by negative tendencies. Old mosques were restored, were under construction new, Islamic schools and high schools were created, was widely studied religious the dogmatic person, the corresponding literature was published, expanded contacts with foreign Muslim brothers in the faith, the centers of the Arab-Muslim culture extended. At the same time in Kazakhstan, there are religious-political parties and movements, pursuing radical goals down to change the spiritual and cultural identity of Muslims of Kazakhstan by the forcible introduction of non-traditional religious and political, ethnic and cultural values.
Abstract: The purpose of this study was to determine the
influence of physical activity and dietary fat intake on Body Mass
Index (BMI) of lecturers within a higher learning institutionalized
setting. The study adopted a Cross-sectional Correlational Design
and included 120 lecturers selected proportionately by simple
random sampling techniques from a population of 600 lecturers. Data
was collected using questionnaires, which had sections including
physical activity checklist adopted from the international physical
activity questionnaire (IPAQ), 24-hour food recall, anthropometric
measurements mainly weight and height. Analysis involved the use
of bivariate correlations and linear regression. A significant inverse
association was registered between BMI and duration (in minutes)
spent doing moderate intense physical activity per day (r=-0.322,
p
Abstract: Induction machine models used for steady-state and
transient analysis require machine parameters that are usually
considered design parameters or data. The knowledge of induction
machine parameters is very important for Indirect Field Oriented
Control (IFOC). A mismatched set of parameters will degrade the
response of speed and torque control. This paper presents an
improvement approach on rotor time constant adaptation in IFOC for
Induction Machines (IM). Our approach tends to improve the
estimation accuracy of the fundamental model for flux estimation.
Based on the reduced order of the IM model, the rotor fluxes and
rotor time constant are estimated using only the stator currents and
voltages. This reduced order model offers many advantages for real
time identification parameters of the IM.
Abstract: The stem cells have ability to differentiated
themselves through mitotic cell division and various range of
specialized cell types. Cellular differentiation is a way by which few
specialized cell develops into more specialized.This paper studies the
fundamental problem of computational schema for an artificial neural
network based on chemical, physical and biological variables of
state. By doing this type of study system could be model for a viable
propagation of various economically important stem cells
differentiation. This paper proposes various differentiation outcomes
of artificial neural network into variety of potential specialized cells
on implementing MATLAB version 2009. A feed-forward back
propagation kind of network was created to input vector (five input
elements) with single hidden layer and one output unit in output
layer. The efficiency of neural network was done by the assessment
of results achieved from this study with that of experimental data
input and chosen target data. The propose solution for the efficiency
of artificial neural network assessed by the comparatative analysis of
“Mean Square Error" at zero epochs. There are different variables of
data in order to test the targeted results.
Abstract: The influence of extrusion parameters on surface
quality and properties of AA6061+x% vol. SiC (x = 0; 2,5; 5; 7,5;10)
composites was discussed in this paper. The averages size of
AA6061 and SiC particles were 10.6 μm and 0.42 μm, respectively.
Two series of composites (I - compacts were preheated at extrusion
temperature through 0.5 h and cooled by water directly after process;
II - compacts were preheated through 3 hours and were not cooled)
were consolidated via powder metallurgy processing and extruded by
KoBo method. High values of density for both series of composites
were achieved. Better surface quality was observed for II series of
composites. Moreover, for these composites lower (compared to I
series) but more uniform strength properties over the cross-section of
the bar were noticed. Microstructure and Young-s modulus
investigations were made.
Abstract: Historic preservation areas are extremely vulnerable to disasters because they are home to many vulnerable people and contain many closely spaced wooden houses. However, the narrow streets in these regions have historic meaning, which means that they cannot be widened and can become blocked easily during large disasters. Here, we describe our efforts to establish a methodology for the planning of evacuation route sin such historic preservation areas. In particular, this study aims to clarify the effectiveness of measures intended to secure two-way evacuation routes for vulnerable people during large disasters in a historic area preserved under the Cultural Properties Protection Law, Japan.
Abstract: Appropriate ventilation in a classroom is helpful for
enhancing air exchange rate and student concentration. This study
focuses on the effects of fenestration in a four-story school building by
performing numerical simulation of a building when considering
indoor and outdoor environments simultaneously. The wind profile
function embedded in PHOENICS code was set as the inlet boundary
condition in a suburban environment. Sixteen fenestration
combinations were compared in a classroom containing thirty seats.
This study evaluates mean age of air (AGE) and airflow pattern of a
classroom on different floors. Considering both wind profile and
fenestration effects, the airflow on higher floors is channeled toward
the area near ceiling in a room and causes older mean age of air in the
breathing zone. The results in this study serve as a useful guide for
enhancing natural ventilation in a typical school building.