Abstract: Breast cancer is the most common malignancy in the
world among women. Many therapies have been designed to treat
this disease. Mamectomy, chemotherapy and radiotherapy are still
the main therapies of breast cancer. However, the results were
unsatisfactory and still far from the ideal treatment.
PM 701is a natural product, has anticancer activity. The bioactive
fraction PMF and subfraction PMFK had been isolated from PM701.
PM 701 and its fractions were proved to have a cytotoxic properties
against different cancer cell lines. This article is directed for the
further examination of lyophilized PM701 and its active fractions on
the growth of breast cancer cells (MCF-7). PM 701, PMF or PMFK
were adding to the cultural medium, where MCF-7 is incubated.
PM 701, PMF or PMFK were able to inhibit significantly the
proliferation of MCF-7 cells, Moreover these new agents were
proved to induce apoptosis of the breast cancer cells; through its
direct effect on the nuclei.
Abstract: The purpose of this study was to examine a broader range of sport constraints perceived by young Koreans in Australia who may need to adjust to changing behavioral expectations due to the socio-cultural transitions. Regardless of gender, in terms of quantitative findings, the most important participation constraints within the seven categories were resources, access, interpersonal, affective, religious, socio-cultural, and physical in that order. The most important constraining items were a lack of time, access, information, adaptive skills, and parental and family support in that order. Qualitative research found young Korean’s participation constraints among three categories (time, parental control and interpersonal constraints). It is possible that different ethnic groups would be constrained by different factors; however, this is outside the scope of this study.
Abstract: It is widely acknowledged that there is a shortage of software developers, not only in South Africa, but also worldwide. Despite reports on a gap between industry needs and software education, the gap has mostly been explored in quantitative studies. This paper reports on the qualitative data of a mixed method study of the perceptions of professional software developers regarding what topics they learned from their formal education and the importance of these topics to their actual work. The analysis suggests that there is a gap between industry’s needs and software development education and the following recommendations are made: 1) Real-life projects must be included in students’ education; 2) Soft skills and business skills must be included in curricula; 3) Universities must keep the curriculum up to date; 4) Software development education must be made accessible to a diverse range of students.
Abstract: The nature of wireless ad hoc and sensor networks
make them very attractive to attackers. One of the most popular and
serious attacks in wireless ad hoc networks is wormhole attack and
most proposed protocols to defend against this attack used
positioning devices, synchronized clocks, or directional antennas.
This paper analyzes the nature of wormhole attack and existing
methods of defending mechanism and then proposes round trip time
(RTT) and neighbor numbers based wormhole detection mechanism.
The consideration of proposed mechanism is the RTT between two
successive nodes and those nodes- neighbor number which is needed
to compare those values of other successive nodes. The identification
of wormhole attacks is based on the two faces. The first consideration
is that the transmission time between two wormhole attack affected
nodes is considerable higher than that between two normal neighbor
nodes. The second detection mechanism is based on the fact that by
introducing new links into the network, the adversary increases the
number of neighbors of the nodes within its radius. This system does
not require any specific hardware, has good performance and little
overhead and also does not consume extra energy. The proposed
system is designed in ad hoc on-demand distance vector (AODV)
routing protocol and analysis and simulations of the proposed system
are performed in network simulator (ns-2).
Abstract: A unique combination of adsorption and
electrochemical regeneration with a proprietary adsorbent material
called Nyex 100 was introduced at the University of Manchester for
waste water treatment applications. Nyex 100 is based on graphite
intercalation compound. It is non porous and electrically conducing
adsorbent material. This material exhibited very small BET surface
area i.e. 2.75 m2g-1, in consequence, small adsorptive capacities for
the adsorption of various organic pollutants were obtained. This work
aims to develop composite adsorbent material essentially capable of
electrochemical regeneration coupled with improved adsorption
characteristics. An organic dye, acid violet 17 was used as standard
organic pollutant. The developed composite material was
successfully electrochemically regenerated using a DC current of 1 A
for 60 minutes. Regeneration efficiency was maintained at around
100% for five adsorption-regeneration cycles.
Abstract: An optimal control problem for a mathematical model of efficiency of antiviral therapy in hepatitis B virus infections is considered. The aim of the study is to control the new viral production, block the new infection cells and maintain the number of uninfected cells in the given range. The optimal controls represent the efficiency of antiviral therapy in inhibiting viral production and preventing new infections. Defining the cost functional, the optimal control problem is converted into the constrained optimization problem and the first order optimality system is derived. For the numerical simulation, we propose the steepest descent algorithm based on the adjoint variable method. A computer program in MATLAB is developed for the numerical simulations.
Abstract: In this paper multi-objective genetic algorithms are
employed for Pareto approach optimization of ideal Turboshaft
engines. In the multi-objective optimization a number of conflicting
objective functions are to be optimized simultaneously. The
important objective functions that have been considered for
optimization are specific thrust (F/m& 0), specific fuel consumption
( P S ), output shaft power 0 (& /&) shaft W m and overall efficiency( ) O
η .
These objectives are usually conflicting with each other. The design
variables consist of thermodynamic parameters (compressor pressure
ratio, turbine temperature ratio and Mach number).
At the first stage single objective optimization has been
investigated and the method of NSGA-II has been used for multiobjective
optimization. Optimization procedures are performed for
two and four objective functions and the results are compared for
ideal Turboshaft engine. In order to investigate the optimal
thermodynamic behavior of two objectives, different set, each
including two objectives of output parameters, are considered
individually. For each set Pareto front are depicted. The sets of
selected decision variables based on this Pareto front, will cause the
best possible combination of corresponding objective functions.
There is no superiority for the points on the Pareto front figure,
but they are superior to any other point. In the case of four objective
optimization the results are given in tables.
Abstract: Abai Kunanbayev is famous for being enlightener,
composer, interpreter, social agent, philosopher, reformer, who
wanted to enrich Kazakh literature by emergence with Russian and
European culture, and also as a founder of Kazakh written literary
language. Abai Kunanbayev was born in 1845 in East Kazakhstan
area and passed away in 1904 in his hometown. His oeuvre absorbed
and reflected all changes in the life of Kazakh society of the second
half of XIX century. Because ХІХ century, especially its second half,
was an important transition period for Kazakhstan, which radically
changed traditional way of Kazakh society and predetermined further
development in consequence of activation of Russian colonial policy
and approval of commodity-money relations in Steppe Land.Abai
Kunanbayev, besides Arabic and Persian common words and
loanwords from Quran in his words of edification, had used a lot of
words of Arabic, Persian, Latin, Russian, Nogai, Shaghatai, Polish,
Greek, Turkish, which are used in the Kazakh language.
Abstract: The six sigma method is a project-driven management approach to improve the organization-s products, services, and processes by continually reducing defects in the organization. Understanding the key features, obstacles, and shortcomings of the six sigma method allows organizations to better support their strategic directions, and increasing needs for coaching, mentoring, and training. It also provides opportunities to better implement six sigma projects. The purpose of this paper is the survey of six sigma process and its impact on the organizational productivity. So I have studied key concepts , problem solving process of six sigmaas well as the survey of important fields such as: DMAIC, six sigma and productivity applied programme, and other advantages of six sigma. In the end of this paper, present research conclusions. (direct and positive relation between six sigma and productivity)
Abstract: Arbitrarily shaped video objects are an important
concept in modern video coding methods. The techniques presently
used are not based on image elements but rather video objects having
an arbitrary shape. In this paper, spatial shape error concealment
techniques to be used for object-based image in error-prone
environments are proposed. We consider a geometric shape
representation consisting of the object boundary, which can be
extracted from the α-plane. Three different approaches are used to
replace a missing boundary segment: Bézier interpolation, Bézier
approximation and NURBS approximation. Experimental results on
object shape with different concealment difficulty demonstrate the
performance of the proposed methods. Comparisons with proposed
methods are also presented.
Abstract: Despite many success stories of manufacturing safety, many organizations are still reluctant, perceiving it as cost increasing and time consuming. The clear contributor may be due to the use of lagging indicators rather than leading indicator measures. The study therefore proposes a combinatorial model for determining the best safety strategy. A combination theory and cost benefit analysis was employed to develop a monetary saving / loss function in terms value of preventions and cost of prevention strategy. Documentations, interviews and structured questionnaire were employed to collect information on Before-And-After safety programme records from a Tobacco company between periods of 1993-2001(for pre-safety) and 2002-2008 (safety period) for the model application. Three combinatorial alternatives A, B, C were obtained resulting into 4, 6 and 4 strategies respectively with PPE and Training being predominant. A total of 728 accidents were recorded for a 9 year period of pre-safety programme and 163 accidents were recorded for 7 years period of safety programme. Six preventions activities (alternative B) yielded the best results. However, all the years of operation experienced except year 2004. The study provides a leading resources for planning successful safety programme
Abstract: In this paper an analytical crack propagation scenario
is proposed which assumes that a crack propagates in the tooth root in
both the crack depth direction and the tooth width direction, and
which is more reasonable and realistic for non-uniform load
distribution cases than the other presented scenarios. An analytical
approach is used for quantifying the loss of time-varying gear mesh
stiffness with the presence of crack propagation in the gear tooth root.
The proposed crack propagation scenario can be applied for crack
propagation modelling and monitoring simulation, but further
research is required for comparison and evaluation of all the
presented crack propagation scenarios from the condition monitoring
point of view.
Abstract: In the last decades to supply the various and different
demands of clients, a lot of manufacturers trend to use the mixedmodel
assembly line (MMAL) in their production lines, since this
policy make possible to assemble various and different models of the
equivalent goods on the same line with the MTO approach.
In this article, we determine the sequence of (MMAL) line, with
applying the kitting approach and planning of rest time for general
workers to reduce the wastages, increase the workers effectiveness
and apply the sector of lean production approach.
This Multi-objective sequencing problem solved in small size with
GAMS22.2 and PSO meta heuristic in 10 test problems and compare
their results together and conclude that their results are very similar
together, next we determine the important factors in computing the
cost, which improving them cost reduced. Since this problem, is NPhard
in large size, we use the particle swarm optimization (PSO)
meta-heuristic for solving it. In large size we define some test
problems to survey it-s performance and determine the important
factors in calculating the cost, that by change or improved them
production in minimum cost will be possible.
Abstract: In response to address different development challenges, Tanzania is striving to achieve its fourth attribute of the National Development Vision, i.e. to have a well educated and learned society by the year 2025. One of the most cost effective methods that can reach a large part of the society in a short time is to integrate ICT in education through e-learning initiatives. However, elearning initiatives are challenged by limited or lack of connectivity to majority of secondary schools, especially those in rural and remote areas. This paper has explores the possibility for rural secondary school to access online e-Learning resources from a centralized e- Learning Management System (e-LMS). The scope of this paper is limited to schools that have computers irrespective of internet connectivity, resulting in two categories schools; those with internet access and those without. Different connectivity configurations have been proposed according to the ICT infrastructure status of the respective schools. However, majority of rural secondary schools in Tanzania have neither computers nor internet connection. Therefore this is a challenge to be addressed for the disadvantaged schools to benefit from e-Learning initiatives.
Abstract: Planning capacities when regenerating complex investment goods involves particular challenges in that the planning is subject to a large degree of uncertainty regarding load information. Using information fusion – by applying Bayesian Networks – a method is being developed for forecasting the anticipated expenditures (human labor, tool and machinery utilization, time etc.) for regenerating a good. The generated forecasts then later serve as a tool for planning capacities and ensure a greater stability in the planning processes.
Abstract: Web applications have become very complex and
crucial, especially when combined with areas such as CRM
(Customer Relationship Management) and BPR (Business Process
Reengineering), the scientific community has focused attention to
Web applications design, development, analysis, and testing, by
studying and proposing methodologies and tools. This paper
proposes an approach to automatic multi-dimensional concern
mining for Web Applications, based on concepts analysis, impact
analysis, and token-based concern identification. This approach lets
the user to analyse and traverse Web software relevant to a particular
concern (concept, goal, purpose, etc.) via multi-dimensional
separation of concerns, to document, understand and test Web
applications. This technique was developed in the context of WAAT
(Web Applications Analysis and Testing) project. A semi-automatic
tool to support this technique is currently under development.
Abstract: This study examined a habitat-suitability assessment method namely the Ecological Niche Factor Analysis (ENFA). A virtual species was created and then dispatched in a geographic information system model of a real landscape in three historic scenarios: (1) spreading, (2) equilibrium, and (3) overabundance. In each scenario, the virtual species was sampled and these simulated data sets were used as inputs for the ENFA to reconstruct the habitat suitability model. The 'equilibrium' scenario gives the highest quantity and quality among three scenarios. ENFA was sensitive to the distribution scenarios but not sensitive to sample sizes. The use of a virtual species proved to be a very efficient method, allowing one to fully control the quality of the input data as well as to accurately evaluate the predictive power of the analyses.
Abstract: Creating3D environments, including characters and
cities, is a significantly time consuming process due to a large amount
of workinvolved in designing and modelling.There have been a
number of attempts to automatically generate 3D objects employing
shape grammars. However it is still too early to apply the mechanism
to real problems such as real-time computer games.The purpose of this
research is to introduce a time efficient and cost effective method to
automatically generatevarious 3D objects for real-time 3D games.
This Shape grammar-based real-time City Generation (RCG) model is
a conceptual model for generating 3Denvironments in real-time and
can be applied to 3D gamesoranimations. The RCG system can
generate even a large cityby applying fundamental principles of shape
grammars to building elementsin various levels of detailin real-time.
Abstract: The processing of the electrocardiogram (ECG) signal consists essentially in the detection of the characteristic points of
signal which are an important tool in the diagnosis of heart diseases. The most suitable are the detection of R waves. In this paper, we
present various mathematical tools used for filtering ECG using digital filtering and Discreet Wavelet Transform (DWT) filtering. In
addition, this paper will include two main R peak detection methods
by applying a windowing process: The first method is based on calculations derived, the second is a time-frequency method based on
Dyadic Wavelet Transform DyWT.
Abstract: Canola is a specific edible type of rapeseed, developed
in the 1970s, which contains about 40 percent oil. This research was
carried out to determine the yield and some quality characteristics of
some winter canola cultivars during the 2010-2011 vegetation period
in Central Anatolia of Turkey. In this research; Oase, Dante,
Californium, Excalibur, Elvis, ES Hydromel, Licord, Orkan, Vectra,
Nelson, Champlain and NK Petrol winter canola varieties were used
as material. The field experiment was set up in a “Randomized
Complete Block Design” with three replications on 21 September
2010. In this research; seed yield, oil content, protein content, oil
yield and protein yield were examined.
As a result of this research; seed yield, oil content, oil yield and
protein yield (except protein content) were significant differences
between the cultivars. The highest seed yield (6348 kg ha-1) was
obtained from the NK Petrol, while the lowest seed yield (3949 kg
ha-1) was determined from the Champlain cultivar was obtained. The
highest oil content (46.73%) was observed from Oase and the lowest
value was obtained from Vectra (41.87%) cultivar. The highest oil
yield (2950 kg ha-1) was determined from NK Petrol while the least
value (1681 kg ha-1) was determined from Champlain cultivar. The
highest protein yield (1539.3 kg ha-1) was obtained from NK Petrol
and the lowest protein yield (976.5 kg ha-1) was obtained from
Champlain cultivar.
The main purpose of the cultivation of oil crops, to increase the
yield of oil per unit area. According the result of this research, NK
Petrol cultivar which ranks first with regard to both seed yield and oil
yield between cultivars as the most suitable winter canola cultivar of
local conditions.