Abstract: The study of proteomics reached unexpected levels of
interest, as a direct consequence of its discovered influence over
some complex biological phenomena, such as problematic diseases
like cancer. This paper presents a new technique that allows for an
accurate analysis of the human interactome network. It is basically
a two-step analysis process that involves, at first, the detection of
each protein-s absolute importance through the betweenness centrality
computation. Then, the second step determines the functionallyrelated
communities of proteins. For this purpose, we use a community
detection technique that is based on the edge betweenness
calculation. The new technique was thoroughly tested on real biological
data and the results prove some interesting properties of those proteins that are involved in the carcinogenesis process. Apart from its
experimental usefulness, the novel technique is also computationally
effective in terms of execution times. Based on the analysis- results, some topological features of cancer mutated proteins are presented
and a possible optimization solution for cancer drugs design is suggested.
Abstract: This paper is concerned with the role strategic
management plays in higher education and the methods it entails.
Using the University of West Bohemia and the Czech Republic as
examples, the paper describes the methods used in furthering
strategic objectives within institutions and their different parts
(faculties, institutes). The nature of the demands faced by the
university dictates the need for a strategic framework which defines
the basic objectives and parameters of tertiary education and research
in a local, regional and national context. Sharing strategies with a
wider range of actors (universities, cities, regions, the practical
sphere) is key to laying the foundations for more efficient
cooperation.
Abstract: This paper shows a new method for design of fuzzy observers for Takagi-Sugeno systems. The method is based on Linear matrix inequalities (LMIs) and it allows to insert H constraint into the design procedure. The speed of estimation can tuned be specification of a decay rate of the observer closed loop system. We discuss here also the influence of parametric uncertainties at the output control system stability.
Abstract: Project managers are the ultimate responsible for the
overall characteristics of a project, i.e. they should deliver the project
on time with minimum cost and with maximum quality. It is vital for
any manager to decide a trade-off between these conflicting
objectives and they will be benefited of any scientific decision
support tool. Our work will try to determine optimal solutions (rather
than a single optimal solution) from which the project manager will
select his desirable choice to run the project. In this paper, the
problem in project scheduling notated as
(1,T|cpm,disc,mu|curve:quality,time,cost) will be studied. The
problem is multi-objective and the purpose is finding the Pareto
optimal front of time, cost and quality of a project
(curve:quality,time,cost), whose activities belong to a start to finish
activity relationship network (cpm) and they can be done in different
possible modes (mu) which are non-continuous or discrete (disc), and
each mode has a different cost, time and quality . The project is
constrained to a non-renewable resource i.e. money (1,T). Because
the problem is NP-Hard, to solve the problem, a meta-heuristic is
developed based on a version of genetic algorithm specially adapted
to solve multi-objective problems namely FastPGA. A sample project
with 30 activities is generated and then solved by the proposed
method.
Abstract: Despite the fact that Arabic language is currently one
of the most common languages worldwide, there has been only a
little research on Arabic speech recognition relative to other
languages such as English and Japanese. Generally, digital speech
processing and voice recognition algorithms are of special
importance for designing efficient, accurate, as well as fast automatic
speech recognition systems. However, the speech recognition process
carried out in this paper is divided into three stages as follows: firstly,
the signal is preprocessed to reduce noise effects. After that, the
signal is digitized and hearingized. Consequently, the voice activity
regions are segmented using voice activity detection (VAD)
algorithm. Secondly, features are extracted from the speech signal
using Mel-frequency cepstral coefficients (MFCC) algorithm.
Moreover, delta and acceleration (delta-delta) coefficients have been
added for the reason of improving the recognition accuracy. Finally,
each test word-s features are compared to the training database using
dynamic time warping (DTW) algorithm. Utilizing the best set up
made for all affected parameters to the aforementioned techniques,
the proposed system achieved a recognition rate of about 98.5%
which outperformed other HMM and ANN-based approaches
available in the literature.
Abstract: Solid waste can be considered as an urban burden or
as a valuable resource depending on how it is managed. To meet the
rising demand for energy and to address environmental concerns, a
conversion from conventional energy systems to renewable resources
is essential. For the sustainability of human civilization, an
environmentally sound and techno-economically feasible waste
treatment method is very important to treat recyclable waste. Several
technologies are available for realizing the potential of solid waste as
an energy source, ranging from very simple systems for disposing of
dry waste to more complex technologies capable of dealing with
large amounts of industrial waste. There are three main pathways for
conversion of waste material to energy: thermo chemical,
biochemical and physicochemical. This paper investigates the thermo
chemical conversion of solid waste for energy recovery. The
processes, advantages and dis-advantages of various thermo chemical
conversion processes are discussed and compared. Special attention
is given to Gasification process as it provides better solutions
regarding public acceptance, feedstock flexibility, near-zero
emissions, efficiency and security. Finally this paper presents
comparative statements of thermo chemical processes and introduces
an integrated waste management system.
Abstract: A computational platform is presented in this
contribution. It has been designed as a virtual laboratory to be used
for exploring optimization algorithms in biological problems. This
platform is built on a blackboard-based agent architecture. As a test
case, the version of the platform presented here is devoted to the
study of protein folding, initially with a bead-like description of the
chain and with the widely used model of hydrophobic and polar
residues (HP model). Some details of the platform design are
presented along with its capabilities and also are revised some
explorations of the protein folding problems with different types of
discrete space. It is also shown the capability of the platform to
incorporate specific tools for the structural analysis of the runs in
order to understand and improve the optimization process.
Accordingly, the results obtained demonstrate that the ensemble of
computational tools into a single platform is worthwhile by itself,
since experiments developed on it can be designed to fulfill different
levels of information in a self-consistent fashion. By now, it is being
explored how an experiment design can be useful to create a
computational agent to be included within the platform. These
inclusions of designed agents –or software pieces– are useful for the
better accomplishment of the tasks to be developed by the platform.
Clearly, while the number of agents increases the new version of the
virtual laboratory thus enhances in robustness and functionality.
Abstract: Multiphasing of dc-dc converters has been known to give technical and economical benefits to low voltage high power buck regulator modules. A major advantage of multiphasing dc-dc converters is the improvement of input and output performances in the buck converter. From this aspect, a potential use would be in renewable energy where power quality plays an important factor. This paper presents the design of a 2-phase 200W boost converter for battery charging application. Analysis of results from hardware measurement of the boost converter demonstrates the benefits of using multiphase. Results from the hardware prototype of the 2-phase boost converter further show the potential extension of multiphase beyond its commonly used low voltage high current domains.
Abstract: The article deals with the classification of alternative water resources in terms of potential risks which is the prerequisite for incorporating these water resources to the emergency plans. The classification is based on the quantification of risks resulting from possible damage, disruption or total destruction of water resource caused by natural and anthropogenic hazards, assessment of water quality and availability, traffic accessibility of the assessed resource and finally its water yield. The aim is to achieve the development of an integrated rescue system, which will be capable of supplying the population with drinking water on the whole stricken territory during the states of emergency.
Abstract: In this paper, a novel copyright protection scheme for digital images based on Visual Cryptography and Statistics is proposed. In our scheme, the theories and properties of sampling distribution of means and visual cryptography are employed to achieve the requirements of robustness and security. Our method does not need to alter the original image and can identify the ownership without resorting to the original image. Besides, our method allows multiple watermarks to be registered for a single host image without causing any damage to other hidden watermarks. Moreover, it is also possible for our scheme to cast a larger watermark into a smaller host image. Finally, experimental results will show the robustness of our scheme against several common attacks.
Abstract: The modeling of sound radiation is of fundamental importance for understanding the propagation of acoustic waves and, consequently, develop mechanisms for reducing acoustic noise. The propagation of acoustic waves, are involved in various phenomena such as radiation, absorption, transmission and reflection. The radiation is studied through the linear equation of the acoustic wave that is obtained through the equation for the Conservation of Momentum, equation of State and Continuity. From these equations, is the Helmholtz differential equation that describes the problem of acoustic radiation. In this paper we obtained the solution of the Helmholtz differential equation for an infinite cylinder in a pulsating through free and homogeneous. The analytical solution is implemented and the results are compared with the literature. A numerical formulation for this problem is obtained using the Boundary Element Method (BEM). This method has great power for solving certain acoustical problems in open field, compared to differential methods. BEM reduces the size of the problem, thereby simplifying the input data to be worked and reducing the computational time used.
Abstract: Bean common mosaic necrosis virus (BCMNV) is a
potyvirus with a worldwide distribution. This virus causes serious
economic losses in Iran in many leguminoses. During 20008,
samples were collected from soybeans fields in Tehran Province.
Four isolates (S1, S2 and S3) were inoculated on 15 species of
Cucurbitaceae, Chenopodiaceae, Solanacae and Leguminosae.
Chenopodium quinoa and C. amaranticolor.
Did not developed any symptoms.all isolates caused mosaic
symptoms on Phaseolus vulgaris cv. Red Kidney and P. vulgaris cv.
Bountiful. The molecular weights of coat protein using SDS-PAGE
and western blotting were estimated at 33 kDa. Reverse transcription
polymerase chain reaction (RT-PCR) was performed using one
primer pairs designed by L. XU et al. An approximately 920 bp
fragment was amplified with a specific primer.
Abstract: Ten lactating multiparous Holstein cows were used in
a cross-over design with two dietary treatments and 28-d periods
(with 14 d as an adaptation) to study the effect of restaurant fat on
milk production and composition. Each cow was offered 14.7 kg
DM /d of the basal concentrate diet based on barley and corn (crude
protein = 17.7%, neutral detergent fiber = 23.5%, and acid detergent
fiber = 5.8% of dry matter) with free access to alfalfa. Dietary
treatments were arranged as supplying each cow with 0 (CONTROL)
or 150 g/day (RF) of restaurant fat. Supplemental RF did not
significantly (P > 0.25) affect milk yield, composition, and
composition yields, except for milk fat contents. Milk fat contents
were depressed (P < 0.05) with supplemental RF. Our results indicate
that RF could depress milk fat without affecting milk yield and that
the depression in milk fat in response to RF precedes the depression
in milk yield.
Abstract: One of the purposes of the robust method of
estimation is to reduce the influence of outliers in the data, on the
estimates. The outliers arise from gross errors or contamination from
distributions with long tails. The trimmed mean is a robust estimate.
This means that it is not sensitive to violation of distributional
assumptions of the data. It is called an adaptive estimate when the
trimming proportion is determined from the data rather than being
fixed a “priori-.
The main objective of this study is to find out the robustness
properties of the adaptive trimmed means in terms of efficiency, high
breakdown point and influence function. Specifically, it seeks to find
out the magnitude of the trimming proportion of the adaptive
trimmed mean which will yield efficient and robust estimates of the
parameter for data which follow a modified Weibull distribution with
parameter λ = 1/2 , where the trimming proportion is determined by a
ratio of two trimmed means defined as the tail length. Secondly, the
asymptotic properties of the tail length and the trimmed means are
also investigated. Finally, a comparison is made on the efficiency of
the adaptive trimmed means in terms of the standard deviation for the
trimming proportions and when these were fixed a “priori".
The asymptotic tail lengths defined as the ratio of two trimmed
means and the asymptotic variances were computed by using the
formulas derived. While the values of the standard deviations for the
derived tail lengths for data of size 40 simulated from a Weibull
distribution were computed for 100 iterations using a computer
program written in Pascal language.
The findings of the study revealed that the tail lengths of the
Weibull distribution increase in magnitudes as the trimming
proportions increase, the measure of the tail length and the adaptive
trimmed mean are asymptotically independent as the number of
observations n becomes very large or approaching infinity, the tail
length is asymptotically distributed as the ratio of two independent
normal random variables, and the asymptotic variances decrease as
the trimming proportions increase. The simulation study revealed
empirically that the standard error of the adaptive trimmed mean
using the ratio of tail lengths is relatively smaller for different values
of trimming proportions than its counterpart when the trimming
proportions were fixed a 'priori'.
Abstract: A combination of photosynthetic bacteria along with
anaerobic acidogenic bacteria is an ideal option for efficient
hydrogen production. In the present study, the optimum
concentration of substrates for the growth of Rhodobacter
sphaeroides was found by response surface methodology. The
optimum combination of three individual fatty acids was determined
by Box Behnken design. Increase of volatile fatty acid concentration
decreased the growth. Combination of sodium acetate and sodium
propionate was most significant for the growth of the organism. The
results showed that a maximum biomass concentration of 0.916 g/l
was obtained when the concentrations of acetate, propionate and
butyrate were 0.73g/l,0.99g/l and 0.799g/l, respectively. The growth
was studied under an optimum concentration of volatile fatty acids
and at a light intensity of 3000 lux, initial pH of 7 and a temperature
of 35°C.The maximum biomass concentration of 0.92g/l was
obtained which verified the practicability of this optimization.
Abstract: In this paper, the process of obtaining Q and R
matrices for optimal pitch aircraft control system has been described.
Since the innovation of optimal control method, the determination of
Q and R matrices for such system has not been fully specified. The
value of Q and R for optimal pitch aircraft control application, have
been simulated and calculated. The suitable results for Q and R have
been observed through the performance index (PI). If the PI is small
“enough", we would say the Q & R values are suitable for that
certain type of optimal control system. Moreover, for the same value
of PI, we could have different Q and R sets. Due to the rule-free
determination of Q and R matrices, a specific method is brought to
find out the rough value of Q and R referring to rather small value of
PI.
Abstract: When earthquakes strike the city it results in great loss of lives. The present paper talks about a new innovative design system (MegEifel) for buildings which has a mechanism to mitigate deaths in case any earthquake strikes the city. If buildings will be designed according to MegEifel design then the occupants of the building will be safe even when they are in sleep or are doing day wise activities during the time earthquake strikes. The core structure is suggested to be designed on the principle that more deep the foundations are, the harder it is to uproot the structure. The buildings will have an Eifel rod dug deep into earth which will help save lives in tall buildings when earthquake strikes. This design takes a leverage of protective shells to save lives.
Abstract: The problem of wastewater treatment in Egypt is a two-fold problem; the first part concerning the existing rural areas, the second one dealing with new industrial/domestic areas. In Egypt several agricultural projects have been initiated by the government and the private sector as well, in order to change its infrastructure. As a reliable energy source, photovoltaic pumping systems have contributed to supply water for local rural communities worldwide; they can also be implemented to solve the problem “wastewater environment pollution". The solution of this problem can be categorised as recycle process. In addition, because of regional conditions past technologies are being reexamined to select a smallscale treatment system requiring low construction and maintenance costs. This paper gives the design guidelines of a Photovoltaic Small- Scale Wastewater Treatment Plant (PVSSWTP) based on technologies that can be transferred.
Abstract: The machining performance is determined by the
frequency characteristics of the machine-tool structure and the
dynamics of the cutting process. Therefore, the prediction of dynamic
vibration behavior of spindle tool system is of great importance for the
design of a machine tool capable of high-precision and high-speed
machining. The aim of this study is to develop a finite element model
to predict the dynamic characteristics of milling machine tool and
hence evaluate the influence of the preload of the spindle bearings. To
this purpose, a three dimensional spindle bearing model of a high
speed engraving spindle tool was created. In this model, the rolling
interfaces with contact stiffness defined by Harris model were used to
simulate the spindle bearing components. Then a full finite element
model of a vertical milling machine was established by coupling the
spindle tool unit with the machine frame structure. Using this model,
the vibration mode that had a dominant influence on the dynamic
stiffness was determined. The results of the finite element simulations
reveal that spindle bearing with different preloads greatly affect the
dynamic behavior of the spindle tool unit and hence the dynamic
responses of the vertical column milling system. These results were
validated by performing vibration on the individual spindle tool unit
and the milling machine prototype, respectively. We conclude that
preload of the spindle bearings is an important component affecting
the dynamic characteristics and machining performance of the entire
vertical column structure of the milling machine.
Abstract: This paper presents a new hardware interface using a
microcontroller which processes audio music signals to standard
MIDI data. A technique for processing music signals by extracting
note parameters from music signals is described. An algorithm to
convert the voice samples for real-time processing without complex
calculations is proposed. A high frequency microcontroller as the
main processor is deployed to execute the outlined algorithm. The
MIDI data generated is transmitted using the EIA-232 protocol. The
analyses of data generated show the feasibility of using
microcontrollers for real-time MIDI generation hardware interface.