Scholarly

Fractal Dimension of Breast Cancer Cell Migration in a Wound Healing Assay

Year: 2008 Volume: 2 Issue: 8 161 - 166 Pages

Abstract: Migration in breast cancer cell wound healing assay had been studied using image fractal dimension analysis. The migration of MDA-MB-231 cells (highly motile) in a wound healing assay was captured using time-lapse phase contrast video microscopy and compared to MDA-MB-468 cell migration (moderately motile). The Higuchi fractal method was used to compute the fractal dimension of the image intensity fluctuation along a single pixel width region parallel to the wound. The near-wound region fractal dimension was found to decrease three times faster in the MDA-MB- 231 cells initially as compared to the less cancerous MDA-MB-468 cells. The inner region fractal dimension was found to be fairly constant for both cell types in time and suggests a wound influence range of about 15 cell layer. The box-counting fractal dimension method was also used to study region of interest (ROI). The MDAMB- 468 ROI area fractal dimension was found to decrease continuously up to 7 hours. The MDA-MB-231 ROI area fractal dimension was found to increase and is consistent with the behavior of a HGF-treated MDA-MB-231 wound healing assay posted in the public domain. A fractal dimension based capacity index has been formulated to quantify the invasiveness of the MDA-MB-231 cells in the perpendicular-to-wound direction. Our results suggest that image intensity fluctuation fractal dimension analysis can be used as a tool to quantify cell migration in terms of cancer severity and treatment responses.

Interaction Effect of Feed Rate and Cutting Speed in CNC-Turning on Chip Micro-Hardness of 304- Austenitic Stainless Steel

Year: 2007 Volume: 1 Issue: 4 152 - 157 Pages

Authors:
G. H. Senussi

Abstract: The present work is concerned with the effect of turning process parameters (cutting speed, feed rate, and depth of cut) and distance from the center of work piece as input variables on the chip micro-hardness as response or output. Three experiments were conducted; they were used to investigate the chip micro-hardness behavior at diameter of work piece for 30[mm], 40[mm], and 50[mm]. Response surface methodology (R.S.M) is used to determine and present the cause and effect of the relationship between true mean response and input control variables influencing the response as a two or three dimensional hyper surface. R.S.M has been used for designing a three factor with five level central composite rotatable factors design in order to construct statistical models capable of accurate prediction of responses. The results obtained showed that the application of R.S.M can predict the effect of machining parameters on chip micro-hardness. The five level factorial designs can be employed easily for developing statistical models to predict chip micro-hardness by controllable machining parameters. Results obtained showed that the combined effect of cutting speed at it?s lower level, feed rate and depth of cut at their higher values, and larger work piece diameter can result increasing chi micro-hardness.

An investigation on the Effect of Continuous Phase Height on the First and Second Critical Rotor Speeds in a Rotary Disc Contactor

Year: 2010 Volume: 4 Issue: 1 41 - 46 Pages

Abstract: A Rotary Disc Contactor with inner diameter of 9.1cm and maximum operating height of 40cm has been used to investigate break up phenomenon. Water-Toluene, Water as continuous phase and Toluene as dispersed phase, was selected as chemical system in the experiments. The mentioned chemical system has high interfacial tension so it was possible to form big drops which permit accurate investigation on break up phenomenon as well as the first and second critical rotor speeds. In this study, Break up phenomenon has been studied as a function of mother drop size, rotor speed and continuous phase height. Further more; the effects of mother drop size and continuous phase height on the first and second critical rotor speeds were investigated. Finally, two modified correlations were proposed to estimate the first and second critical speeds.

Fabrication and Characterization of Poly-Si Vertical Nanowire Thin Film Transistor

Year: 2011 Volume: 5 Issue: 9 764 - 766 Pages

Abstract: In this paper, we present a vertical nanowire thin film transistor with gate-all-around architecture, fabricated using CMOS compatible processes. A novel method of fabricating polysilicon vertical nanowires of diameter as small as 30 nm using wet-etch is presented. Both n-type and p-type vertical poly-silicon nanowire transistors exhibit superior electrical characteristics as compared to planar devices. On a poly-crystalline nanowire of 30 nm diameter, high Ion/Ioff ratio of 106, low drain-induced barrier lowering (DIBL) of 50 mV/V, and low sub-threshold slope SS~100mV/dec are demonstrated for a device with channel length of 100 nm.

Distributor Plate Design and a System for Collection of Granules in a Device with a Vortex Fluidized Bed

Year: 2011 Volume: 5 Issue: 11 953 - 956 Pages

Abstract: A newly designed gas-distributor for granulation of powdery materials in equilibrated fluidized bed and a system for collecting the granules prepared are suggested. The aim of these designs is to solve the problems arising by the granulation of powdery materials in fluidized bed devices. The gasdistributor and the collection system proved to be reliable at operation; they reduce the size of still zones, effectively disperse the binding solution in the bed and ensure the collection of granules of given diameter

Stochastic Modeling and Combined Spatial Pattern Analysis of Epidemic Spreading

Year: 2011 Volume: 5 Issue: 3 252 - 259 Pages

Abstract: We present analysis of spatial patterns of generic disease spread simulated by a stochastic long-range correlation SIR model, where individuals can be infected at long distance in a power law distribution. We integrated various tools, namely perimeter, circularity, fractal dimension, and aggregation index to characterize and investigate spatial pattern formations. Our primary goal was to understand for a given model of interest which tool has an advantage over the other and to what extent. We found that perimeter and circularity give information only for a case of strong correlation– while the fractal dimension and aggregation index exhibit the growth rule of pattern formation, depending on the degree of the correlation exponent (β). The aggregation index method used as an alternative method to describe the degree of pathogenic ratio (α). This study may provide a useful approach to characterize and analyze the pattern formation of epidemic spreading

Synthesis and Thermoelectric Behavior in Nanoparticles of Doped Co Ferrites

Year: 2011 Volume: 5 Issue: 4 572 - 574 Pages

Abstract: Samples of CoFe2-xCrxO4 where x varies from 0.0 to 0.5 were prepared by co-precipitation route. These samples were sintered at 750°C for 2 hours. These particles were characterized by X-ray diffraction (XRD) at room temperature. The FCC spinel structure was confirmed by XRD patterns of the samples. The crystallite sizes of these particles were calculated from the most intense peak by Scherrer formula. The crystallite sizes lie in the range of 37-60 nm. The lattice parameter was found decreasing upon substitution of Cr. DC electrical resistivity was measured as a function of temperature. The room temperature thermoelectric power was measured for the prepared samples. The magnitude of Seebeck coefficient depends on the composition and resistivity of the samples.

Context Aware Lightweight Energy Efficient Framework

Year: 2009 Volume: 3 Issue: 4 279 - 285 Pages

Abstract: Context awareness is a capability whereby mobile computing devices can sense their physical environment and adapt their behavior accordingly. The term context-awareness, in ubiquitous computing, was introduced by Schilit in 1994 and has become one of the most exciting concepts in early 21st-century computing, fueled by recent developments in pervasive computing (i.e. mobile and ubiquitous computing). These include computing devices worn by users, embedded devices, smart appliances, sensors surrounding users and a variety of wireless networking technologies. Context-aware applications use context information to adapt interfaces, tailor the set of application-relevant data, increase the precision of information retrieval, discover services, make the user interaction implicit, or build smart environments. For example: A context aware mobile phone will know that the user is currently in a meeting room, and reject any unimportant calls. One of the major challenges in providing users with context-aware services lies in continuously monitoring their contexts based on numerous sensors connected to the context aware system through wireless communication. A number of context aware frameworks based on sensors have been proposed, but many of them have neglected the fact that monitoring with sensors imposes heavy workloads on ubiquitous devices with limited computing power and battery. In this paper, we present CALEEF, a lightweight and energy efficient context aware framework for resource limited ubiquitous devices.

A Comparative Study of Thai and Balinese Temple Festival Dress

Year: 2013 Volume: 7 Issue: 5 1153 - 1156 Pages

Authors:
Jaruphan Supprung

Abstract: Aims of this research were to study Thai Buddhist temple festivals and Balinese Hindu temple festivals, to compare Thai Buddhist temple festival dress with Balinese Hindu temple festival dress, and to create the knowledge which can be useful for Thai attitudes and cultural perceptions, especially for Thai children and youth. The findings of the research disclosed that there are four temple festivals of Thai Buddhists in Thailand, namely Songkran Festival, Buddhist Lent Festival, Sart Thai Festival and End of Buddhist Lent Festival. In island of Bali, Indonesia, there are three Balinese Hindu temple festivals, namely Odalan Festival, Galungan Festival and Nyepi Festival. Thai Songkran Festival is similar to New Year Celebration in Balinese Nyepi Festival. Thai Songkran Festival and Sart Thai Festival have the same purpose as that of Balinese Galungan Festival in practice of dedicating merit to the spirits of deceased relatives. In these temple festivals, Thai Buddhist men will wear round collar outerwear and wide leg trousers or loincloths but will never wear headdresses, while Balinese Hindu men wear turbans or fabric headbands, shirts and Sarong, which are similar to Sarong of Thai Buddhist men in central and northern part of Thailand. Most of Thai Buddhist women wear Sarong like Balinese Hindu women but wear only round collar outerwear, while Balinese Hindu women wear diamond neck camisole as inner wear and shawl collar as outerwear.

Energy Density Increasing in the Channel of Super-High Pressure Megaampere Discharge due to Resonance of Different Type Oscillations of the Channel

Year: 2012 Volume: 6 Issue: 11 1472 - 1477 Pages

Abstract: Discharges in hydrogen, ignited by wire explosion, with current amplitude up to 1.5 MA were investigated. Channel diameter oscillations were observed on the photostreaks. Voltage and current curves correlated with the photostreaks. At initial gas pressure of 5-35 MPa the oscillation period was proportional to square root of atomic number of the initiating wire material. These oscillations were associated with aligned magnetic and gas-kinetic pressures. At initial pressure of 80-160 MPa acoustic pressure fluctuations on the discharge chamber wall were increased up to 150 MPa and there were the growth of voltage fluctuations on the discharge gap up to 3 kV simultaneously with it. In some experiments it was observed abrupt increase in the oscillation amplitude, which can be caused by the resonance of the acoustic oscillations in discharge chamber volume and the oscillations connected with alignment of the gaskinetic pressure and the magnetic pressure, as far as frequencies of these oscillations are close to each other in accordance with the estimates and the experimental data. Resonance of different type oscillations can produce energy density increasing in the discharge channel. Thus, the appropriate initial conditions in the experiment allow to increase the energy density in the discharge channel

Kinetics of Palm Oil Cracking in Batch Reactor

Year: 2013 Volume: 7 Issue: 1 15 - 19 Pages

Abstract: The kinetics of palm oil catalytic cracking over aluminum containing mesoporous silica Al-MCM-41 (5% Al) was investigated in a batch autoclave reactor at the temperatures range of 573 – 673 K. The catalyst was prepared by using sol-gel technique and has been characterized by nitrogen adsorption and x-ray diffraction methods. Surface area of 1276 m2/g with average pore diameter of 2.54 nm and pore volume of 0.811 cm3/g was obtained. The experimental catalytic cracking runs were conducted using 50 g of oil and 1 g of catalyst. The reaction pressure was recorded at different time intervals and the data were analyzed using Levenberg- Marquardt (LM) algorithm using polymath software. The results show that the reaction order was found to be -1.5 and activation energy of 3200 J/gmol.

Combining Molecular Statics with Heat Transfer Finite Difference Method for Analysis of Nanoscale Orthogonal Cutting of Single-Crystal Silicon Temperature Field

Year: 2013 Volume: 7 Issue: 7 1426 - 1435 Pages

Abstract: This paper uses quasi-steady molecular statics model and diamond tool to carry out simulation temperature rise of nanoscale orthogonal cutting single-crystal silicon. It further qualitatively analyzes temperature field of silicon workpiece without considering heat transfer and considering heat transfer. This paper supposes that the temperature rise of workpiece is mainly caused by two heat sources: plastic deformation heat and friction heat. Then, this paper develops a theoretical model about production of the plastic deformation heat and friction heat during nanoscale orthogonal cutting. After the increased temperature produced by these two heat sources are added up, the acquired total temperature rise at each atom of the workpiece is substituted in heat transfer finite difference equation to carry out heat transfer and calculates the temperature field in each step and makes related analysis.

Mathematical Modelling of Venturi Scrubber for Ammonia Absorption

Year: 2012 Volume: 6 Issue: 1 56 - 58 Pages

Abstract: In this study, the dispersed model is used to predict gas phase concentration, liquid drop concentration. The venturi scrubber efficiency is calculated by gas phase concentration. The modified model has been validated with available experimental data of Johnstone, Field and Tasler for a range of throat gas velocities, liquid to gas ratios and particle diameters and is used to study the effect of some design parameters on collection efficiency.

Solid Concentration in Circulating Fluidized Bed Reactor for the MTO Process

Year: 2010 Volume: 4 Issue: 1 34 - 40 Pages

Abstract: Methanol-to-olefins (MTO) coupled with transformation of coal or natural gas to methanol gives an interesting and promising way to produce ethylene and propylene. To investigate solid concentration in gas-solid fluidized bed for methanol-to-olefins process catalyzed by SAPO-34, a cold model experiment system is established in this paper. The system comprises a gas distributor in a 300mm internal diameter and 5000mm height acrylic column, the fiber optic probe system and series of cyclones. The experiments are carried out at ambient conditions and under different superficial gas velocity ranging from 0.3930m/s to 0.7860m/s and different initial bed height ranging from 600mm to 1200mm. The effects of radial distance, axial distance, superficial gas velocity, initial bed height on solid concentration in the bed are discussed. The effects of distributor shape and porosity on solid concentration are also discussed. The time-averaged solid concentration profiles under different conditions are obtained.

Investigation on Metalosalen Complexes Binding to DNA using Ab Initio Calculations

Year: 2011 Volume: 5 Issue: 9 760 - 763 Pages

Abstract: Geometry optimizations of metal complexes of Salen(bis(Salicylidene)1,2-ethylenediamine) were carried out at HF and DFT methods employing Lanl2DZ basis set. In this work structural, energies, bond lengths and other physical properties between Mn2+,Cu2+ and Ni2+ ions coordinated by salen–type ligands are examined. All calculations were performed using Gaussian 98W program series. To investigate local aromaticities, NICS were calculated at all centers of rings. The higher the band gap indicating a higher global aromaticity. The possible binding energies have been evaluated. We have evaluated Frequencies and Zero-point energy with freq calculation. The NICS(Nucleous Independent Chemical Shift) Results show Ni(II) complexes are antiaromatic and aromaticites of Mn(II) complexes are larger than Cu(II) complexes. The energy Results show Cu(II) complexes are stability than Mn(II) and Ni(II) complexes.

Geometric and Material Nonlinear Analysis of Reinforced Concrete Structure Considering Soil-Structure Interaction

Year: 2012 Volume: 6 Issue: 10 809 - 821 Pages

Abstract: In the present research, a finite element model is presented to study the geometrical and material nonlinear behavior of reinforced concrete plane frames considering soil-structure interaction. The nonlinear behaviors of concrete and reinforcing steel are considered both in compression and tension up to failure. The model takes account also for the number, diameter, and distribution of rebar along every cross section. Soil behavior is taken into consideration using four different models; namely: linear-, nonlinear Winkler's model, and linear-, nonlinear continuum model. A computer program (NARC) is specially developed in order to perform the analysis. The results achieved by the present model show good agreement with both theoretical and experimental published literature. The nonlinear behavior of a rectangular frame resting on soft soil up to failure using the proposed model is introduced for demonstration.

Advantages of Large Strands in Precast/Prestressed Concrete Highway Application

Year: 2013 Volume: 7 Issue: 9 667 - 669 Pages

Authors:
Amin Akhnoukh

Abstract: The objective of this research is to investigate the advantages of using large-diameter 0.7 inch prestressing strands in pretention applications. The advantages of large-diameter strands are mainly beneficial in the heavy construction applications. Bridges and tunnels are subjected to a higher daily traffic with an exponential increase in trucks ultimate weight, which raise the demand for higher structural capacity of bridges and tunnels. In this research, precast prestressed I-girders were considered as a case study. Flexure capacities of girders fabricated using 0.7 inch strands and different concrete strengths were calculated and compared to capacities of 0.6 inch strands girders fabricated using equivalent concrete strength. The effect of bridge deck concrete strength on composite deck-girder section capacity was investigated due to its possible effect on final section capacity. Finally, a comparison was made to compare the bridge cross-section of girders designed using regular 0.6 inch strands and the large-diameter 0.7 inch. The research findings showed that structural advantages of 0.7 inch strands allow for using fewer bridge girders, reduced material quantity, and light-weight members. The structural advantages of 0.7 inch strands are maximized when high strength concrete (HSC) are used in girder fabrication, and concrete of minimum 5ksi compressive strength is used in pouring bridge decks. The use of 0.7 inch strands in bridge industry can partially contribute to the improvement of bridge conditions, minimize construction cost, and reduce the construction duration of the project.

More Realistic Model for Simulating Min Protein Dynamics: Lattice Boltzmann Method Incorporating the Role of Nucleoids

Year: 2010 Volume: 4 Issue: 7 451 - 456 Pages

Abstract: The dynamics of Min proteins plays a center role in accurate cell division. Although the nucleoids may presumably play an important role in prokaryotic cell division, there is a lack of models to account for its participation. In this work, we apply the lattice Boltzmann method to investigate protein oscillation based on a mesoscopic model that takes into account the nucleoid-s role. We found that our numerical results are in reasonably good agreement with the previous experimental results On comparing with the other computational models without the presence of nucleoids, the highlight of our finding is that the local densities of MinD and MinE on the cytoplasmic membrane increases, especially along the cell width, when the size of the obstacle increases, leading to a more distinct cap-like structure at the poles. This feature indicated the realistic pattern and reflected the combination of Min protein dynamics and nucleoid-s role.

Response of Chickpea Genotypes to Drought

Year: 2012 Volume: 6 Issue: 6 329 - 334 Pages

Abstract: Water is the main component of biological processes. Water management is important to obtain higher productivity. In this study, some of the yield components were investigated together with different drought levels. Four chickpea genotypes (CDC Frontier, CDC Luna, Sawyer and Sierra) were grown in pots with 3 different irrigation levels (a dose of 17.5 ml, 35 ml and 70 ml for each pot per day) after three weeks from sowing. In the research, flowering, pod set, pod per plant, fertile pod, double seed/pod, stem diameter, plant weight, seed per plant, 1000 seed weight, seed diameter, vegetation length and weekly plant height were measured. Consequently, significant differences were observed on all the investigated characteristics owing to genotypes (except double seed/pod and stem diameter), water levels (except first pod, seed weight and height on 3rd week) and genotype x water level interaction (except first pod, double seed/pod, seed weight and height).

Prestressed Concrete Girder Bridges Using Large 0.7 Inch Strands

Year: 2013 Volume: 7 Issue: 9 662 - 666 Pages

Authors:
Amin Akhnoukh

Abstract: The National Bridge Inventory (NBI) includes more than 600,000 bridges within the United States of America. Prestressed concrete girder bridges represent one of the most widely used bridge systems. The majority of these girder bridges were constructed using 0.5 and 0.6 inch diameter strands. The main impediments to using larger strand diameters are: 1) lack of prestress bed capacities, 2) lack of structural knowledge regarding the transfer and development length of larger strands, and 3) the possibility of developing wider end zone cracks upon strand release. This paper presents a study about using 0.7 inch strands in girder fabrication. Transfer and development length were evaluated, and girders were fabricated using 0.7 inch strands at different spacings. Results showed that 0.7 inch strands can be used at 2.0 inch spacing without violating the AASHTO LRFD Specifications, while attaining superior performance in shear and flexure.

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