Abstract: Background: The objectives of this study were to
assess patient’s knowledge of appropriate sublingual glyceryl
trinitrate (GTN) use as well as to investigate how patients commonly
store and carry their sublingual GTN tablets. Methodology: This was
a cross-sectional survey, using a validated researcher-administered
questionnaire. The study involved cardiac patients receiving
sublingual GTN attending the outpatient and inpatient departments of
Taiping Hospital, a non-academic public care hospital. The minimum
calculated sample size was 92, but 100 patients were conveniently
sampled. Respondents were interviewed on 3 areas, including
demographic data, knowledge and use of sublingual GTN. Eight
items were used to calculate each subject’s knowledge score and six
items were used to calculate use score. Results: Of the 96 patients
who consented to participate, majority (96.9%) were well aware of
the indication of sublingual GTN. With regards to the mechanism of
action of sublingual GTN, 73 (76%) patients did not know how the
medication works. Majority of the patients (66.7%) knew about the
proper storage of the tablet. In relation to the maximum number of
sublingual GTN tablets that can be taken during each angina episode,
36.5% did not know that up to 3 tablets of sublingual GTN can be
taken during each episode of angina. Fifty four (56.2%) patients were
not aware that they need to replace sublingual GTN every 8 weeks
after receiving the tablets. Majority (69.8%) of the patients
demonstrated lack of knowledge with regards to the use of sublingual
GTN as prevention of chest pain. Conclusion: Overall, patients’
knowledge regarding the self-administration of sublingual GTN is
still inadequate. The findings support the need for more frequent
reinforcement of patient education, especially in the areas of
preventive use, storage and drug stability.
Abstract: Comparing other methods of waste water treatment,
constructed wetlands are one of the most fascinating practices
because being a natural process they are eco-friendly have low
construction and maintenance cost and have considerable capability
of wastewater treatment. The current research was focused mainly on
comparison of Ranunculus muricatus and Typha latifolia as wetland
plants for domestic wastewater treatment by designing and
constructing efficient pilot scale horizontal subsurface flow
mesocosms. Parameters like chemical oxygen demand, biological
oxygen demand, phosphates, sulphates, nitrites, nitrates, and
pathogenic indicator microbes were studied continuously with
successive treatments. Treatment efficiency of the system increases
with passage of time and with increase in temperature. Efficiency of
T. latifolia planted setups in open environment was fairly good for
parameters like COD and BOD5 which was showing reduction up to
82.5% for COD and 82.6% for BOD5 while DO was increased up to
125%. Efficiency of R. muricatus vegetated setup was also good but
lowers than that of T. latifolia planted showing 80.95% removal of
COD and BOD5. Ranunculus muricatus was found effective in
reducing bacterial count in wastewater. Both macrophytes were
found promising in wastewater treatment.
Abstract: Attributes and methods are the basic contents of an
object-oriented class. The connectivity among these class members
and the relationship between the class and other classes play an
important role in determining the quality of an object-oriented
system. Class cohesion evaluates the degree of relatedness of class
attributes and methods, whereas class coupling refers to the degree to
which a class is related to other classes. Researchers have proposed
several class cohesion and class coupling measures. However, the
correlation between class coupling and class cohesion measures has
not been thoroughly studied. In this paper, using classes of three
open-source Java systems, we empirically investigate the correlation
between several measures of connectivity-based class cohesion and
coupling. Four connectivity-based cohesion measures and eight
coupling measures are considered in the empirical study. The
empirical study results show that class connectivity-based cohesion
and coupling internal quality attributes are inversely correlated. The
strength of the correlation depends highly on the cohesion and
coupling measurement approaches.
Abstract: Nowadays, huge amount of multimedia repositories
make the browsing, retrieval and delivery of video contents very slow
and even difficult tasks. Video summarization has been proposed to
improve faster browsing of large video collections and more efficient
content indexing and access. In this paper, we focus on approaches to
video summarization. The video summaries can be generated in many
different forms. However, two fundamentals ways to generate
summaries are static and dynamic. We present different techniques
for each mode in the literature and describe some features used for
generating video summaries. We conclude with perspective for
further research.
Abstract: Offering a Product-Service System (PSS) is a
well-accepted strategy that companies may adopt to provide a set of
systemic solutions to customers. PSSs were initially provided in a
simple form but now take diversified and complex forms involving
multiple services, products and technologies. With the growing
interest in the PSS, frameworks for the PSS development have been
introduced by many researchers. However, most of the existing
frameworks fail to examine various relations existing in a complex
PSS. Since designing a complex PSS involves full integration of
multiple products and services, it is essential to identify not only
product-service relations but also product-product/ service-service
relations. It is also equally important to specify how they are related
for better understanding of the system. Moreover, as customers tend to
view their purchase from a more holistic perspective, a PSS should be
developed based on the whole system’s requirements, rather than
focusing only on the product requirements or service requirements.
Thus, we propose a framework to develop a complex PSS that is
coordinated fully with the requirements of both worlds. Specifically,
our approach adopts a multi-domain matrix (MDM). A MDM
identifies not only inter-domain relations but also intra-domain
relations so that it helps to design a PSS that includes highly desired
and closely related core functions/ features. Also, various dependency
types and rating schemes proposed in our approach would help the
integration process.
Abstract: Despite the highly touted benefits, emerging
technologies have unleashed pervasive concerns regarding unintended
and unforeseen social impacts. Thus, those wishing to create safe and
socially acceptable products need to identify such side effects and
mitigate them prior to the market proliferation. Various methodologies
in the field of technology assessment (TA), namely Delphi, impact
assessment, and scenario planning, have been widely incorporated in
such a circumstance. However, literatures face a major limitation in
terms of sole reliance on participatory workshop activities. They
unfortunately missed out the availability of a massive untapped data
source of futuristic information flooding through the Internet. This
research thus seeks to gain insights into utilization of futuristic data,
future-oriented documents from the Internet, as a supplementary
method to generate social impact scenarios whilst capturing
perspectives of experts from a wide variety of disciplines. To this end,
network analysis is conducted based on the social keywords extracted
from the futuristic documents by text mining, which is then used as a
guide to produce a comprehensive set of detailed scenarios. Our
proposed approach facilitates harmonized depictions of possible
hazardous consequences of emerging technologies and thereby makes
decision makers more aware of, and responsive to, broad qualitative
uncertainties.
Abstract: Pulmonary Function Tests are important non-invasive
diagnostic tests to assess respiratory impairments and provides
quantifiable measures of lung function. Spirometry is the most
frequently used measure of lung function and plays an essential role
in the diagnosis and management of pulmonary diseases. However,
the test requires considerable patient effort and cooperation,
markedly related to the age of patients resulting in incomplete data
sets. This paper presents, a nonlinear model built using Multivariate
adaptive regression splines and Random forest regression model to
predict the missing spirometric features. Random forest based feature
selection is used to enhance both the generalization capability and the
model interpretability. In the present study, flow-volume data are
recorded for N= 198 subjects. The ranked order of feature importance
index calculated by the random forests model shows that the
spirometric features FVC, FEF25, PEF, FEF25-75, FEF50 and the
demographic parameter height are the important descriptors. A
comparison of performance assessment of both models prove that, the
prediction ability of MARS with the `top two ranked features namely
the FVC and FEF25 is higher, yielding a model fit of R2= 0.96 and
R2= 0.99 for normal and abnormal subjects. The Root Mean Square
Error analysis of the RF model and the MARS model also shows that
the latter is capable of predicting the missing values of FEV1 with a
notably lower error value of 0.0191 (normal subjects) and 0.0106
(abnormal subjects) with the aforementioned input features. It is
concluded that combining feature selection with a prediction model
provides a minimum subset of predominant features to train the
model, as well as yielding better prediction performance. This
analysis can assist clinicians with a intelligence support system in the
medical diagnosis and improvement of clinical care.
Abstract: In the framework of the modernization of the city of
Constantine and in order to restore its status as a regional metropolis
introducing it into the network of cities international metropolises,
has major urban project was launched: project of modernization and
of metropolitanization of the city of Constantine.
Our research project focuses on the management of the project for
the modernization of the city of Constantine (PMMC) focusing on
the management of some aspects of the urban project whose
participation, with the objective assessment of the managerial
approach business.
In this contribution, we focus on two cases revealing taken into
account in our research work on the question of participation of
actors and their organizations. It is "the urban project of
modernization of Constantine" and the operation relating to "the
urban improvement in the city of the Brothers FERRAD in the
district of Zouaghi". This project and this operation with the objective
of improving the living conditions of citizens have faced several
challenges and obstacles that have been in major part the factors of its
failures.
Through this study, we examined the management process and the
mode of organization of the actors of the project as well as the level
of participation of the citizen to finally proposed managerial solutions
toconflict situations observed.
Abstract: Hurling a successful Construction and Demolition
Waste (C&DW) recycling operation around the globe is a challenge
today, predominantly because secondary materials markets are yet to
be integrated. Reducing, Reusing and recycling of (C&DW) have
been employed over the years, and various techniques have been
investigated. However, the economic and environmental viability of
its application seems limited. This paper discusses the costs and
benefits in using secondary materials and focus on investigating reuse
and recycling process for five major types of construction materials:
concrete, metal, wood, cardboard/paper and plasterboard. Data
obtained from demolition specialists and contractors are considered
and evaluated. The research paper found that construction material
recovery process fully incorporate a 3R’s principle contributing to
saving energy and natural resources. This scrutiny leads to the
empathy of grand challenges in construction material recovery
process. Recommendations to deepen material recovery process are
also discussed.
Abstract: This study is to fill up a research gap on examining the
differences in normative beliefs (namely acceptance of weaknesses,
acceptance of provoked aggression, and acceptance of unprovoked
aggression) among different subtypes of aggressors and
non-aggressors (reactive aggressors, proactive aggressors,
reactive-proactive aggressors, and non-aggressors). 2,236 students
(1,372 males and 864 females), aged from 11 to 18, completed a
self-reported questionnaire. Results revealed that (a) schoolchildren
with reactive-proactive aggression have the highest acceptance of
provoked aggression, the highest acceptance of unprovoked
aggression, and the lowest acceptance of weakness; (b) schoolchildren
with proactive aggression have higher acceptance of unprovoked
aggression and lower acceptance of weakness than reactive aggressors;
and (c) schoolchildren without aggression have the lowest acceptance
of provoked aggression, the lowest acceptance of unprovoked
aggression, and the highest acceptance of weakness.
Abstract: This research has been conducted to study the method
of culture and comparing growth and biomass of Gracilaria corticata
cultured on rope and net for 50 days through two treatments (first
treatment: culture of alga on net and the second treatment: culture of
alga on rope and each treatment was repeated by four cases). During
culture period, the water of aquariums was replaced once every two
days for 40-50%. Also, 0.3-0.5 grams of urea fertilizer was added to
the culture environment for fertilization. Moreover, some of the
environmental factors such as pH, salinity and temperature of the
environment were measured on a daily basis. During the culture
period, extent of longitudinal growth of the species of both treatments
was equal. The said length was reached from 8-10 cm to 10.5-13 cm
accordingly. The resulted weight in repetitions of the first treatment
was higher than that of the second treatment in such a way as in the
first treatment, its weight reached from 10 grams to 21.119 grams and
in the second treatment, its weight reached from 10 grams to 17.663
grams. On a whole, it may be stated that that kind of alga being
studied has a considerable growth with respect to its volume. The
results have revealed that the percentage of daily growth and wet
weight at the end of the first treatment was higher than that of the
second treatment and it was registered as 0.934, 6.072 and 811.432 in
the first treatment and 0.797, 4.990 and 758.071 in the second
treatment respectively. This difference is significant (P
Abstract: Robotic surgery is used to enhance minimally invasive
surgical procedure. It provides greater degree of freedom for surgical
tools but lacks of haptic feedback system to provide sense of touch to
the surgeon. Surgical robots work on master-slave operation, where
user is a master and robotic arms are the slaves. Current, surgical
robots provide precise control of the surgical tools, but heavily rely
on visual feedback, which sometimes cause damage to the inner
organs. The goal of this research was to design and develop a realtime
Simulink based robotic system to study force feedback
mechanism during instrument-object interaction. Setup includes three
VelmexXSlide assembly (XYZ Stage) for three dimensional
movement, an end effector assembly for forceps, electronic circuit for
four strain gages, two Novint Falcon 3D gaming controllers,
microcontroller board with linear actuators, MATLAB and Simulink
toolboxes. Strain gages were calibrated using Imada Digital Force
Gauge device and tested with a hard-core wire to measure
instrument-object interaction in the range of 0-35N. Designed
Simulink model successfully acquires 3D coordinates from two
Novint Falcon controllers and transfer coordinates to the XYZ stage
and forceps. Simulink model also reads strain gages signal through
10-bit analog to digital converter resolution of a microcontroller
assembly in real time, converts voltage into force and feedback the
output signals to the Novint Falcon controller for force feedback
mechanism. Experimental setup allows user to change forward
kinematics algorithms to achieve the best-desired movement of the
XYZ stage and forceps. This project combines haptic technology
with surgical robot to provide sense of touch to the user controlling
forceps through machine-computer interface.
Abstract: Skin aging is a slow multifactorial process influenced
by both internal as well as external factors. Ultra-violet radiations
(UV), diet, smoking and personal habits are the most common
environmental factors that affect skin aging. Fat contents and fibrous
proteins as collagen and elastin are core internal structural
components. The direct influence of UV on elastin integrity and
health is central on aging of skin especially by time. The deposition
of abnormal elastic material is a major marker in a photo-aged skin.
Searching for compounds that may protect against cutaneous photodamage
is exceedingly valued. Retinoids and alpha hydroxy acids
have been endorsed by some researchers as possible candidates for
protecting and or repairing the effect of UV damaged skin. For
consolidating a better system of anti- and protective effects of such
anti-aging agents, we evaluated the combinatory effects of various
dosages of lactic acid and retinol on the dermal fibroblast’s elastin
levels exposed to UV. The UV exposed cells showed significant
reduction in the elastin levels. A combination of drugs with a higher
concentration of lactic acid (30 -35 mM) and a lower concentration of
retinol (10-15mg/mL) showed to work better in maintaining elastin
concentration in UV exposed cells. We assume this preservation
could be the result of increased tropo-elastin gene expression
stimulated by retinol whereas lactic acid probably repaired the UV
irradiated damage by enhancing the amount and integrity of the
elastin fibers.
Abstract: This paper addresses the issue of the autonomous
mobile robot (AMR) navigation task based on the hybrid control
modes. The novel hybrid control mode, based on multi-sensors
information by using the fuzzy approach, has been presented in this
research. The system operates in real time, is robust, enables the robot
to operate with imprecise knowledge, and takes into account the
physical limitations of the environment in which the robot moves,
obtaining satisfactory responses for a large number of different
situations. An experiment is simulated and carried out with a pioneer
mobile robot. From the experimental results, the effectiveness and
usefulness of the proposed AMR obstacle avoidance and navigation
scheme are confirmed. The experimental results show the feasibility,
and the control system has improved the navigation accuracy. The
implementation of the controller is robust, has a low execution time,
and allows an easy design and tuning of the fuzzy knowledge base.
Abstract: Activated carbons (M4P0, M4P2, and M5P2) used in
this research were produced from palm shell and polyetherether
ketone (PEEK) via carbonization, impregnation and microwave
activation. The adsorption/desorption process was carried out using
static volumetric adsorption. Regeneration is important in the overall
economy of the process and waste minimization. This work focuses
on the thermal regeneration of the CO2 exhausted microwave
activated carbons. The regeneration strategy adopted was thermal
with nitrogen purge desorption with N2 feed flow rate of 20 ml/min
for 1 h at atmospheric pressure followed by drying at 150oC.Seven
successive adsorption/regeneration processes were carried out on the
material. It was found that after seven adsorption regeneration cycles;
the regeneration efficiency (RE) for CO2 activated carbon from palm
shell only (M4P0) was more than 90% while that of hybrid palm
shell-PEEK (M4P2, M5P2) was above 95%. The cyclic adsorption
and regeneration shows the stability of the adsorbent materials.
Abstract: In this paper, we used data mining to extract
biomedical knowledge. In general, complex biomedical data
collected in studies of populations are treated by statistical methods,
although they are robust, they are not sufficient in themselves to
harness the potential wealth of data. For that you used in step two
learning algorithms: the Decision Trees and Support Vector Machine
(SVM). These supervised classification methods are used to make the
diagnosis of thyroid disease. In this context, we propose to promote
the study and use of symbolic data mining techniques.
Abstract: Paints are the most widely used methods of protection
against atmospheric corrosion of metals. The aim of this work was to
determine the protective performance of epoxy coating against sea
water before and after damage.
Investigations are conducted using stationary and non-stationary
electrochemical tools such as electrochemical impedance
spectroscopy has allowed us to characterize the protective qualities of
these films. The application of the EIS on our damaged in-situ
painting shows the existence of several capacitive loops which is an
indicator of the failure of our tested paint. Microscopic analysis
(micrograph) helped bring essential elements in understanding the
degradation of our paint condition and immersion training corrosion
products.
Abstract: Presently, it is necessary to ensure the sustainable
development of passenger and freight transport. Increasing
performance of road freight has had a negative impact to environment
and society. It is therefore necessary to increase the competitiveness
of intermodal transport, which is more environmentally friendly. The
study describes the effectiveness of logistical centers realization for
companies and society and research how the partial internalization of
external costs reflected in the efficient use of these centers and
increase the competitiveness of intermodal transport to road freight.
In our research, we use the method of comparative analysis and
market research to describe the advantages of logistic centers for their
users as well as for society as a whole. Method normal costing is used
for calculation infrastructure and total costs, method of conversion
costing for determine the external costs. We modelled total society
costs for road freight transport and inter modal transport chain (we
assumed that most of the traffic is carried by rail) with different
loading schemes for condition in the Slovak Republic. Our research
has shown that higher utilization of inter modal transport chain do
good not only for society, but for companies providing freight
services too. Increase in use of inter modal transport chain can bring
many benefits to society that do not bring direct immediate financial
return. They often bring the multiplier effects, such as greater use of
environmentally friendly transport mode and reduce the total society
costs.
Abstract: Lipases constitute one of the most important groups of
industrial enzymes that catalyze the hydrolysis of triacylglycerol to
glycerol and fatty acids. Muscarinic antagonist relieves smooth
muscle spasm of the gastrointestinal tract and effect on the
cardiovascular system. In this research the effect of a muscarinic
antagonist on the lipase activity of Pseudomonas aeruginosa was
studied. Lineweaver–Burk plot showed that the drug inhibited the
enzyme by competitive inhibition. The IC50 value (0.16 mM) and Ki
(0.03 mM) of the drug revealed the drug bound to enzyme with high
affinity. Determination of enzyme activity in various pH and
temperature showed that the maximum activity of lipase was at pH 8
and 60oC both in presence and absence of the drug.
Abstract: Emissions of atmospheric pollutants from ships and
harbour activities are a growing concern at international level given
their potential impacts on air quality and climate. These close-to-land
emissions have potential impact on local communities in terms of air
quality and health. Recent studies show that the impact of maritime
traffic to atmospheric particulate matter concentrations in several
coastal urban areas is comparable with the impact of road traffic of a
medium size town. However, several different approaches have been
used for these estimates making difficult a direct comparison of
results. In this work, an integrated approach based on emission
inventories and dedicated measurement campaigns has been applied
to give a comparable estimate of the impact of maritime traffic to
PM2.5 and particle number concentrations in three major harbours of
the Adriatic/Ionian Seas. The influences of local meteorology and of
the logistic layout of the harbours are discussed.