Abstract: Co-crystal is believed to improve the solubility and
dissolution rates and thus, enhanced the bioavailability of poor water
soluble drugs particularly during the oral route of administration.
With the existing of poorly soluble drugs in pharmaceutical industry,
the screening of co-crystal formation using carbamazepine (CBZ) as
a model drug compound with dicarboxylic acids co-crystal formers
(CCF) namely fumaric (FA) and succinic (SA) acids in ethanol has
been studied. The co-crystal formations were studied by varying the
mol ratio values of CCF to CBZ to access the effect of CCF
concentration on the formation of the co-crystal. Solvent evaporation,
slurry and cooling crystallization which representing the solution
based method co-crystal screening were used. Based on the
differential scanning calorimetry (DSC) analysis, the melting point of
CBZ-SA in different ratio was in the range between 188oC-189oC.
For CBZ-FA form A and CBZ-FA form B the melting point in
different ratio were in the range of 174oC-175oC and 185oC-186oC
respectively. The product crystal from the screening was also
characterized using X-ray powder diffraction (XRPD). The XRPD
pattern profile analysis has shown that the CBZ co-crystals with FA
and SA were successfully formed for all ratios studied. The findings
revealed that CBZ-FA co-crystal were formed in two different
polymorphs. It was found that CBZ-FA form A and form B were
formed from evaporation and slurry crystallization methods
respectively. On the other hand, in cooling crystallization method,
CBZ-FA form A was formed at lower mol ratio of CCF to CBZ and
vice versa. This study disclosed that different methods and mol ratios
during the co-crystal screening can affect the outcome of co-crystal
produced such as polymorphic forms of co-crystal and thereof. Thus,
it was suggested that careful attentions is needed during the screening
since the co-crystal formation is currently one of the promising
approach to be considered in research and development for
pharmaceutical industry to improve the poorly soluble drugs.
Abstract: Gypsum (CaSO4.2H2O) is a mineral that is found in
large quantities in the Turkey and in the World. In this study, the
dissolution of this mineral in the diammonium hydrogen phosphate
solutions has been studied. The dissolution and dissolution kinetics of
gypsum in diammonium hydrogen phosphate solutions will be useful
for evaluating of solid wastes containing gypsum. Parameters such as
diammonium hydrogen phosphate concentration, temperature and
stirring speed affecting on the dissolution rate of the gypsum in
diammonium hydrogen phosphate solutions were investigated. In
experimental studies have researched effectiveness of the selected
parameters. The dissolution of gypsum were examined in two parts at
low and high temperatures. The experimental results were
successfully correlated by linear regression using Statistica program.
Dissolution curves were evaluated shrinking core models for solidfluid
systems. The activation energy was found to be 34.58 kJ/mol
and 44.45 kJ/mol for the low and the high temperatures. The
dissolution of gypsum was controlled by chemical reaction both low
temperatures and high temperatures.
Abstract: In this paper, a direct power control (DPC)
strategies have been investigated in order to control a high
power AC/DC converter with time variable load. This converter
is composed of a three level three phase neutral point clamped
(NPC) converter as rectifier and an H-bridge four quadrant
current control converter. In the high power application,
controller not only must adjust the desire outputs but also
decrease the level of distortions which are injected to the network
from the converter. Regarding to this reason and nonlinearity
of the power electronic converter, the conventional controllers
cannot achieve appropriate responses. In this research, the
precise mathematical analysis has been employed to design the
appropriate controller in order to control the time variable
load. A DPC controller has been proposed and simulated using
Matlab/ Simulink. In order to verify the simulation result, a real
time simulator- OPAL-RT- has been employed. In this paper,
the dynamic response and stability of the high power NPC
with variable load has been investigated and compared with
conventional types using a real time simulator. The results proved
that the DPC controller is more stable and has more precise
outputs in comparison with conventional controller.
Abstract: In the past researchers have questioned the
effectiveness of ethics training in higher education. Also, there are
observations that support the view that ethical behaviour (range of
actions)/ethical decision making models used in the past make use of
vignettes to explain ethical behaviour. The understanding remains in
the perspective that these vignettes play a limited role in determining
individual intentions and not actions. Some authors have also agreed
that there are possibilities of differences in one’s intentions and
actions. This paper makes an attempt to fill those gaps by evaluating
real actions rather than intentions. In a way this study suggests the
use of an experiential methodology to explore Berlo’s model of
communication as an action along with orchestration of various
principles. To this endeavor, an attempt was made to use
conversational analysis in the pursuance of evaluating ethical
decision making behaviour among students and middle level
managers. The process was repeated six times with the set of an
average of 15 participants. Similarities have been observed in the
behaviour of students and middle level managers that calls for
understanding that both the groups of individuals have no cognizance
of their actual actions. The deliberations derived out of conversation
were taken a step forward for meta-ethical evaluations to portray a
clear picture of ethical behaviour among participants. This study
provides insights for understanding demonstrated unconscious human
behaviour which may fortuitously be termed both ethical and
unethical.
Abstract: The arm length, hand length, hand breadth and middle
finger length of 1540 right-handed industrial workers of Haryana
state was used to assess the relationship between the upper limb
dimensions and stature. Initially, the data were analyzed using basic
univariate analysis and independent t-tests; then simple and multiple
linear regression models were used to estimate stature using SPSS
(version 17). There was a positive correlation between upper limb
measurements (hand length, hand breadth, arm length and middle
finger length) and stature (p < 0.01), which was highest for hand
length. The accuracy of stature prediction ranged from ± 54.897 mm
to ± 58.307 mm. The use of multiple regression equations gave better
results than simple regression equations. This study provides new
forensic standards for stature estimation from the upper limb
measurements of male industrial workers of Haryana (India). The
results of this research indicate that stature can be determined using
hand dimensions with accuracy, when only upper limb is available
due to any reasons likewise explosions, train/plane crashes, mutilated
bodies, etc. The regression formula derived in this study will be
useful for anatomists, archaeologists, anthropologists, design
engineers and forensic scientists for fairly prediction of stature using
regression equations.
Abstract: These days customer satisfaction plays vital role in
any business. When customer searches for a product, significantly a
junk of irrelevant information is what is given, leading to customer
dissatisfaction. To provide exactly relevant information on the
searched product, we are proposing a model of KaaS (Knowledge as
a Service), which pre-processes the information using decision
making paradigm using Multi-agents.
Information obtained from various sources is taken to derive
knowledge and they are linked to Cloud to capture new idea. The
main focus of this work is to acquire relevant information
(knowledge) related to product, then convert this knowledge into a
service for customer satisfaction and deploy on cloud.
For achieving these objectives we are have opted to use multi
agents. They are communicating and interacting with each other,
manipulate information, provide knowledge, to take decisions. The
paper discusses about KaaS as an intelligent approach for Knowledge
acquisition.
Abstract: This paper describes an Action Research project
which was undertaken to inform professional practice in order to
develop a newly created Centre for Student Success in the specific
context of transnational medical and nursing education in the Middle
East. The objectives were to enhance the academic performance,
persistence, integration and personal and professional development of
a multinational study body, in particular in relation to pre-clinical
medical students, and to establish a comfortable, friendly and
student-driven environment within an Irish medical university
recently established in Bahrain. The outcomes of the project resulted
in the development of a specific student success ‘signature’ for this
particular transnational higher education context.
Abstract: The aim of software maintenance is to maintain
the software system in accordance with advancement in software
and hardware technology. One of the early works on software
maintenance is to extract information at higher level of abstraction. In
this paper, we present the process of how to design an information
extraction tool for software maintenance. The tool can extract the
basic information from old programs such as about variables, based
classes, derived classes, objects of classes, and functions. The tool
have two main parts; the lexical analyzer module that can read the
input file character by character, and the searching module which
users can get the basic information from the existing programs. We
implemented this tool for a patterned sub-C++ language as an input
file.
Abstract: The adaptation of social networking sites within
higher education has garnered significant interest in the recent years
with numerous researches considering it as a possible shift from the
traditional classroom based learning paradigm. Notwithstanding this
increase in research and conducted studies however, the adaption of
SNS based modules have failed to proliferate within Universities.
This paper commences its contribution by analyzing the various
models and theories proposed in literature and amalgamate together
various effective aspects for the inclusion of social technology within
e-Learning. A three phased framework is further proposed which
details the necessary considerations for the successful adaptation of
SNS in enhancing the students learning experience. This proposal
outlines the theoretical foundations which will be analyzed in
practical implementation across international university campuses.
Abstract: Cloud computing is a new technology in industry and
academia. The technology has grown and matured in last half decade
and proven their significant role in changing environment of IT
infrastructure where cloud services and resources are offered over the
network. Cloud technology enables users to use services and
resources without being concerned about the technical implications of
technology. There are substantial research work has been performed
for the usage of cloud computing in educational institutes and
majority of them provides cloud services over high-end blade servers
or other high-end CPUs. However, this paper proposes a new stack
called “CiCKAStack” which provide cloud services over unutilized
computing resources, named as commodity computers.
“CiCKAStack” provides IaaS and PaaS using underlying commodity
computers. This will not only increasing the utilization of existing
computing resources but also provide organize file system, on
demand computing resource and design and development
environment.
Abstract: Applications of the Hausdorff space and its mappings
into tangent spaces are outlined, including their fractal dimensions
and self-similarities. The paper details this theory set up and further
describes virtualizations and atomization of manufacturing processes.
It demonstrates novel concurrency principles that will guide
manufacturing processes and resources configurations. Moreover,
varying levels of details may be produced by up folding and breaking
down of newly introduced generic models. This choice of layered
generic models for units and systems aspects along specific aspects
allows research work in parallel to other disciplines with the same
focus on all levels of detail. More credit and easier access are granted
to outside disciplines for enriching manufacturing grounds. Specific
mappings and the layers give hints for chances for interdisciplinary
outcomes and may highlight more details for interoperability
standards, as already worked on the international level. The new rules
are described, which require additional properties concerning all
involved entities for defining distributed decision cycles, again on the
base of self-similarity. All properties are further detailed and assigned
to a maturity scale, eventually displaying the smartness maturity of a
total shopfloor or a factory. The paper contributes to the intensive
ongoing discussion in the field of intelligent distributed
manufacturing and promotes solid concepts for implementations of
Cyber Physical Systems and the Internet of Things into
manufacturing industry, like industry 4.0, as discussed in German-speaking
countries.
Abstract: Nanofibers are effective materials which have
frequently been investigated to produce high quality air filters. As an
environmental approach our aim is to achieve nanofibers by melting.
In spun-bond systems extruder, spin-pump, nozzle package and
attenuator are used. Molten polymer which flows from extruder is
made steady by spin-pump. Regular melt passes through nozzle holes
and forms fibers under high pressure. The fibers pulled from nozzle
are shrunk to micron size by an attenuator; after solidification, they
are collected on a conveyor. In this research different designs of
attenuator system have been studied; and also CFD analysis has been
done on these different designs. Afterwards, one of these designs
tested and finally some optimizations have been done to reduce
pressure loss and increase air velocity.
Abstract: Recently, the competition between websites becomes
intense. How to make users “adopt” their websites is an issue of urgent
importance for online communities companies. Social procedures
(such as social influence) can possibly explain how and why users’
technologies usage behaviors affect other people to use the
technologies. This study proposes two types of social influences on the
initial usage of Facebook Check In-friends and group members.
Besides, this study combines social influences theory and social
network theory to explore the factors influencing initial usage of
Facebook Check In. This study indicates that Facebook friends’
previous usage of Facebook Check In and Facebook group members’
previous usage of Facebook Check In will positively influence focal
actors’ Facebook Check In adoption intention, and network centrality
will moderate the relationships among Facebook friends’ previous
usage of Facebook Check In, Facebook group members’ previous
usage of Facebook Check In and focal actors’ Facebook Check In
adoption intention. The article concludes with contributions to
academic research and practice.
Abstract: In urban context, urban nodes such as amenity or
hazard will certainly affect house price, while classic hedonic analysis
will employ distance variables measured from each urban nodes.
However, effects from distances to facilities on house prices generally
do not represent the true price of the property. Distance variables
measured on the same surface are suffering a problem called
multicollinearity, which is usually presented as magnitude variance
and mean value in regression, errors caused by instability. In this paper,
we provided a theoretical framework to identify and gather the data
with less bias, and also provided specific sampling method on locating
the sample region to avoid the spatial multicollinerity problem in three
distance variable’s case.
Abstract: Nature is the immense gifted source for solving
complex problems. It always helps to find the optimal solution to
solve the problem. Mobile Ad Hoc NETwork (MANET) is a wide
research area of networks which has set of independent nodes. The
characteristics involved in MANET’s are Dynamic, does not depend
on any fixed infrastructure or centralized networks, High mobility.
The Bio-Inspired algorithms are mimics the nature for solving
optimization problems opening a new era in MANET. The typical
Swarm Intelligence (SI) algorithms are Ant Colony Optimization
(ACO), Artificial Bee Colony (ABC), Particle Swarm Optimization
(PSO), Modified Termite Algorithm, Bat Algorithm (BA), Wolf
Search Algorithm (WSA) and so on. This work mainly concentrated
on nature of MANET and behavior of nodes. Also it analyses various
performance metrics such as throughput, QoS and End-to-End delay
etc.
Abstract: This paper aims to investigate the influence of quality
of education and quality of research, provided by local educational
institutions, on the adoption of Information and Communication
Technology (ICT) in managing business operations for companies in
Saudi market. A model was developed and tested using data collected
from 138 Chief Executive Officers (CEOs) of foreign companies in
diverse business sectors. The data is analyzed and managed using
multivariate approaches through standard statistical packages. The
results showed that educational quality has little contribution to the
ICT adoption while research quality seems to play a more prominent
role. These results are analyzed in terms of business environment and
market constraints and further extended to the perceived effectiveness
of applied pedagogical approaches in schools and universities.
Abstract: In a multi-cultural learning context, where ties are
weak and dynamic, combining qualitative with quantitative research
methods may be more effective. Such a combination may also allow
us to answer different types of question, such as about people’s
perception of the network. In this study the use of observation,
interviews and photos were explored as ways of enhancing data from
social network questionnaires. Integrating all of these methods was
found to enhance the quality of data collected and its accuracy, also
providing a richer story of the network dynamics and the factors that
shaped these changes over time.
Abstract: This technical contribution treats of a novel approach
to condition-oriented maintenance as elaborated by Collaborative
Research Centre 653 at the Leibniz University in Hanover. The
objective resides in the targeted analysis of information about a
component's lifecycle for maintenance purposes. The information in
question is collected by means of the Collaborative Research Centre's
innovative technologies. This enables preventive maintenance of
components on the basis of their condition. This contribution initially
explains condition-oriented maintenance, before introducing the
Collaborative Research Centre and finally presenting the
methodology for analyzing the information. The current state of
development is described and an outlook provided for expanding the
methodology.
Abstract: In review the generalized data about biological
activity of anthraquinone-containing plants and specimens on their
basis is presented. Data of traditional medicine, results of
bioscreening and clinical researches of specimens are analyzed.
Abstract: Within the framework of this research, the regulatory
documents, which are in force in relation to this industry, were
analyzed. The main attention is turned to their modernization and
necessity of their compliance with European standards.
It is a current issue to direct the efforts of state policy on support
of business by implementing infrastructural projects, as well as by
development of human resources, which may be possible by
supporting the relevant higher and vocational studying-educational
programs.