Abstract: In the current work, a three-dimensional geometry of a
75% stenosed blood vessel is analyzed. Large eddy simulation (LES)
with the help of a dynamic subgrid scale Smagorinsky model is
applied to model the turbulent pulsatile flow. The geometry, the
transmural pressure and the properties of the blood and the elastic
boundary were based on clinical measurement data. For the flexible
wall model, a thin solid region is constructed around the 75%
stenosed blood vessel. The deformation of this solid region was
modelled as a deforming boundary to reduce the computational cost
of the solid model. Fluid-structure interaction is realized via a twoway
coupling between the blood flow modelled via LES and the
deforming vessel. The information of the flow pressure and the wall
motion was exchanged continually during the cycle by an arbitrary
Lagrangian-Eulerian method. The boundary condition of current time
step depended on previous solutions. The fluctuation of the velocity
in the post-stenotic region was analyzed in the study. The axial
velocity at normalized position Z=0.5 shows a negative value near
the vessel wall. The displacement of the elastic boundary was
concerned in this study. In particular, the wall displacement at the
systole and the diastole were compared. The negative displacement at
the stenosis indicates a collapse at the maximum velocity and the
deceleration phase.
Abstract: The effect of transition metal doping on Pt/Al2O3
catalyst used in propane dehydrogenation reaction at 500°C was
studied. The preparation methods investigated were sequential
impregnation (Pt followed by the 2nd metal or the 2nd metal followed
by Pt) and co-impregnation. The metal contents of these catalysts
were fixed as the weight ratio of Pt per the 2nd metal of around 0.075.
These catalysts were characterized by N2-physisorption, TPR, COchemisorption
and NH3-TPD. It was found that the impregnated 2nd
metal had an effect upon reducibility of Pt due to its interaction with
transition metal-containing structure. This was in agreement with the
CO-chemisorption result that the presence of Pt metal, which is a
result from Pt species reduction, was decreased. The total acidity of
bimetallic catalysts is decreased but the strong acidity is slightly
increased. It was found that the stability of bimetallic catalysts
prepared by co-impregnation and sequential impregnation where the
2nd metal was impregnated before Pt were better than that of
monometallic catalyst (undoped Pt one) due to the forming of Pt sites
located on the transition metal-oxide modified surface. Among all
preparation methods, the sequential impregnation method- having Pt
impregnated before the 2nd metal gave the worst stability because this
catalyst lacked the modified Pt sites and some fraction of Pt sites was
covered by the 2nd metal.
Abstract: The present work describes the implementation of the
Enhanced Collaborative Optimization (ECO) multilevel architecture
with a gradient-based optimization algorithm with the aim of
performing a multidisciplinary design optimization of a generic
unmanned aerial vehicle with morphing technologies. The concepts
of weighting coefficient and dynamic compatibility parameter are
presented for the ECO architecture. A routine that calculates the
aircraft performance for the user defined mission profile and vehicle’s
performance requirements has been implemented using low fidelity
models for the aerodynamics, stability, propulsion, weight, balance
and flight performance. A benchmarking case study for evaluating
the advantage of using a variable span wing within the optimization
methodology developed is presented.
Abstract: The present work analyses different parameters of end
milling to minimize the surface roughness for AISI D2 steel. D2 Steel
is generally used for stamping or forming dies, punches, forming
rolls, knives, slitters, shear blades, tools, scrap choppers, tyre
shredders etc. Surface roughness is one of the main indices that
determines the quality of machined products and is influenced by
various cutting parameters. In machining operations, achieving
desired surface quality by optimization of machining parameters, is a
challenging job. In case of mating components the surface roughness
become more essential and is influenced by the cutting parameters,
because, these quality structures are highly correlated and are
expected to be influenced directly or indirectly by the direct effect of
process parameters or their interactive effects (i.e. on process
environment). In this work, the effects of selected process parameters
on surface roughness and subsequent setting of parameters with the
levels have been accomplished by Taguchi’s parameter design
approach. The experiments have been performed as per the
combination of levels of different process parameters suggested by
L9 orthogonal array. Experimental investigation of the end milling of
AISI D2 steel with carbide tool by varying feed, speed and depth of
cut and the surface roughness has been measured using surface
roughness tester. Analyses of variance have been performed for mean
and signal-to-noise ratio to estimate the contribution of the different
process parameters on the process.
Abstract: Established objective and subjective preconditions for
entrepreneurship, forming the business organically related whole, are
the necessary condition of successful entrepreneurial activities.
Objective preconditions for entrepreneurship are developed by
market economy that should stimulate entrepreneurship by allowing
the use of economic opportunities for all those who want to do
business in respective field while providing guarantees to all owners
and creating a stable business environment for entrepreneurs.
Subjective preconditions of entrepreneurship are formed primarily by
personal characteristics of the entrepreneur. These are his properties,
abilities, skills, physiological and psychological preconditions which
may be inherited, inborn or sequentially developed and obtained
during his life on the basis of education and influences of
surrounding environment. The paper is dealing with issues of
objective and subjective preconditions for entrepreneurship and
provides their analysis in view of the current situation in Slovakia. It
presents risks of the business environment in Slovakia that the Slovak
managers considered the most significant in 2014 and defines the
dominant attributes of the entrepreneur in the current business
environment in Slovakia.
Abstract: Mechanical stress has a strong effect on the magnitude
of the Barkhausen-noise in structural steels. Because the
measurements are performed at the surface of the material, for a
sample sheet, the full effect can be described by a biaxial stress field.
The measured Barkhausen-noise is dependent on the orientation of
the exciting magnetic field relative to the axis of the stress tensor.
The sample inhomogenities including the residual stress also
modifies the angular dependence of the measured Barkhausen-noise.
We have developed a laboratory device with a cross like specimen
for bi-axial bending. The measuring head allowed performing
excitations in two orthogonal directions. We could excite the two
directions independently or simultaneously with different amplitudes.
The simultaneous excitation of the two coils could be performed in
phase or with a 90 degree phase shift. In principle this allows to
measure the Barkhausen-noise at an arbitrary direction without
moving the head, or to measure the Barkhausen-noise induced by a
rotating magnetic field if a linear superposition of the two fields can
be assumed.
Abstract: Human leukocyte antigen (HLA) typing from next
generation sequencing (NGS) data has the potential for applications in
clinical laboratories and population genetic studies. Here we introduce
a novel technique for HLA typing from NGS data based on
read-mapping using a comprehensive reference panel containing all
known HLA alleles and de novo assembly of the gene-specific short
reads. An accurate HLA typing at high-digit resolution was achieved
when it was tested on publicly available NGS data, outperforming
other newly-developed tools such as HLAminer and PHLAT.
Abstract: For centuries humans have used the antimicrobial
properties of copper to their advantage. Yet, after all these years the
underlying mechanisms of copper mediated cell death in various
microbes remain unclear. We had explored the hypothesis that copper
mediated increased levels of lipid peroxidation in the membrane fatty
acids is responsible for increased killing in Escherichia coli. In this
study we show that in both gram positive (Staphylococcus aureus)
and gram negative (Pseudomonas aeruginosa) bacteria there is a
strong correlation between copper mediated cell death and increased
levels of lipid peroxidation. Interestingly, the non-spore forming
gram positive bacteria as well as gram negative bacteria show similar
patterns of cell death, increased levels of lipid peroxidation, as well
as genomic DNA degradation, however there is some difference in
loss in membrane integrity upon exposure to copper alloy surface.
Abstract: Analyzing DNA microarray data sets is a great
challenge, which faces the bioinformaticians due to the complication
of using statistical and machine learning techniques. The challenge
will be doubled if the microarray data sets contain missing data,
which happens regularly because these techniques cannot deal with
missing data. One of the most important data analysis process on
the microarray data set is feature selection. This process finds the
most important genes that affect certain disease. In this paper, we
introduce a technique for imputing the missing data in microarray
data sets while performing feature selection.
Abstract: Vancron 40, a nitrided powder metallurgical tool
Steel, is used in cold work applications where the predominant failure
mechanisms are adhesive wear or galling. Typical applications of
Vancron 40 are among others fine blanking, cold extrusion, deep
drawing and cold work rolls for cluster mills. Vancron 40 positive
results for cold work rolls for cluster mills and as a tool for some
severe metal forming process makes it competitive compared to other
type of work rolls that require higher precision, among others in cold
rolling of thin stainless steel, which required high surface finish
quality. In this project, three roll materials for cold rolling of stainless
steel strip was examined, Vancron 40, Narva 12B (a high-carbon,
high-chromium tool steel alloyed with tungsten) and Supra 3 (a
Chromium-molybdenum tungsten-vanadium alloyed high speed
steel). The purpose of this project was to study the depth profiles of
the ironed stainless steel strips, emergence of galling and to study the
lubrication performance used by steel industries. Laboratory
experiments were conducted to examine scratch of the strip, galling
and surface roughness of the roll materials under severe tribological
conditions. The critical sliding length for onset of galling was
estimated for stainless steel with four different lubricants. Laboratory
experiments result of performance evaluation of resistance capability
of rolls toward adhesive wear under severe conditions for low and
high reductions. Vancron 40 in combination with cold rolling
lubricant gave good surface quality, prevents galling of
metal surfaces and good bearing capacity.
Abstract: The prepreg process among the CFRP (Carbon Fiber
Reinforced Plastic) forming methods is the short term of
‘Pre-impregnation’, which is widely used for aerospace composites
that require a high quality property such as a fiber-reinforced woven
fabric, in which an epoxy hardening resin is impregnated the reality.
However, that this process requires continuous researches and
developments for its commercialization because the delamination
characteristically develops between the layers when a great weight is
loaded from outside to supplement such demerit, three lamination
methods among the prepreg lamination methods of CFRP were
designed to minimize the delamination between the layers due to
external impacts. Further, the newly designed methods and the
existing lamination methods were analyzed through a mechanical
characteristic test, Interlaminar Shear Strength test. The Interlaminar
Shear Strength test result confirmed that the newly proposed three
lamination methods, i.e. the Roll, Half and Zigzag laminations,
presented more excellent strengths compared to the conventional Ply
lamination. The interlaminar shear strength in the roll method with
relatively dense fiber distribution was approximately 1.75% higher
than that in the existing ply lamination method, and in the half method,
it was approximately 0.78% higher.
Abstract: Background and aim: It has not been well studied
whether fentanyl-thiopental (FT) is effective and safe for PSA in
orthopedic procedures in Emergency Department (ED). The aim of
this trial was to evaluate the effectiveness of intravenous FT versus
fentanyl-midazolam (FM) in patients who suffered from shoulder
dislocation or distal radial fracture-dislocation.
Methods: In this randomized double-blinded study, Seventy-six
eligible patients were entered the study and randomly received
intravenous FT or FM. The success rate, onset of action and recovery
time, pain score, physicians’ satisfaction and adverse events were
assessed and recorded by treating emergency physicians. The
statistical analysis was intention to treat.
Results: The success rate after administrating loading dose in FT
group was significantly higher than FM group (71.7% vs. 48.9%,
p=0.04); however, the ultimate unsuccessful rate after 3 doses of
drugs in the FT group was higher than the FM group (3 to 1) but it
did not reach to significant level (p=0.61). Despite near equal onset
of action time in two study group (P=0.464), the recovery period in
patients receiving FT was markedly shorter than FM group
(P
Abstract: Rotary draw bending is a method which is being used
in tube forming. In the tube bending process, the neutral axis moves
towards the inner arc and the wall thickness distribution changes for
tube’s cross section. Thinning takes place in the outer arc of the tube
(extrados) due to the stretching of the material, whereas thickening
occurs in the inner arc of the tube (intrados) due to the comparison of
the material. The calculations of the wall thickness distribution,
neutral axis shifting, and strain distribution have not been accurate
enough, so far. The previous model (the geometrical model)
describes the neutral axis shifting and wall thickness distribution. The
geometrical of the tube, bending radius and bending angle are
considered in the geometrical model, while the influence of the
material properties of the tube forming are ignored. The advanced
model is a modification of the previous model using material
properties that depends on the correction factor. The correction factor
is a purely empirically determined factor. The advanced model was
compared with the Finite element simulation (FE simulation) using a
different bending factor (Bf =bending radius/ diameter of the tube),
wall thickness (Wf = diameter of the tube/ wall thickness), and
material properties (strain hardening exponent). Finite element model
of rotary draw bending has been performed in PAM-TUBE program
(version: 2012). Results from the advanced model resemble the FE
simulation and the experimental test.
Abstract: The effect of the inclusion of thyme and rosemary
essential oils into chitosan films, as well as the microbiological and
physical properties when storing chitosan film with and without the
mentioned inclusion was studied. The film forming solution was
prepared by dissolving chitosan (2%, w/v), polysorbate 80 (4% w/w
CH) and glycerol (16% w/w CH) in aqueous lactic acid solutions
(control). The thyme (TEO) and rosemary (REO) essential oils (EOs)
were included 1:1 w/w (EOs:CH) on their combination 50/50
(TEO:REO). The films were stored at temperatures of 5, 20, 33°C
and a relative humidity of 75% during four weeks. The films with
essential oil inclusion did not show an antimicrobial activity against
strains. This behavior could be explained because the chitosan only
inhibits the growth of microorganisms in direct contact with the
active sites. However, the inhibition capacity of TEO was higher than
the REO and a synergic effect between TEO:REO was found for S.
enteritidis strains in the chitosan solution.
Some physical properties were modified by the inclusion of
essential oils. The addition of essential oils does not affect the
mechanical properties (tensile strength, elongation at break, puncture
deformation), the water solubility, the swelling index nor the DSC
behavior. However, the essential oil inclusion can significantly
decrease the thickness, the moisture content, and the L* value of
films whereas the b* value increased due to molecular interactions
between the polymeric matrix, the loosing of the structure, and the
chemical modifications. On the other hand, the temperature and time
of storage changed some physical properties on the chitosan films.
This could have occurred because of chemical changes, such as
swelling in the presence of high humidity air and the reacetylation of
amino groups. In the majority of cases, properties such as moisture
content, tensile strength, elongation at break, puncture deformation,
a*, b*, chrome, 7E increased whereas water resistance, swelling
index, L*, and hue angle decreased.
Abstract: Chemical Reaction Optimization (CRO) is an
optimization metaheuristic inspired by the nature of chemical
reactions as a natural process of transforming the substances from
unstable to stable states. Starting with some unstable molecules with
excessive energy, a sequence of interactions takes the set to a state of
minimum energy. Researchers reported successful application of the
algorithm in solving some engineering problems, like the quadratic
assignment problem, with superior performance when compared with
other optimization algorithms. We adapted this optimization
algorithm to the Printed Circuit Board Drilling Problem (PCBDP)
towards reducing the drilling time and hence improving the PCB
manufacturing throughput. Although the PCBDP can be viewed as
instance of the popular Traveling Salesman Problem (TSP), it has
some characteristics that would require special attention to the
transactions that explore the solution landscape. Experimental test
results using the standard CROToolBox are not promising for
practically sized problems, while it could find optimal solutions for
artificial problems and small benchmarks as a proof of concept.
Abstract: This paper presents analysis and design of a wideband
Wilkinson power divider for wireless applications. The design is
accomplished by transforming the lengths and impedances of the
quarter wavelength sections of the conventional Wilkinson power
divider into U-shaped sections. The designed power divider is
simulated by using ADS Agilent technologies and CST microwave
studio software. It is shown that the proposed power divider has
simple topology and good performances in terms of insertion loss,
port matching and isolation at all operating frequencies (1.8 GHz,
2.45 GHz and 3.55 GHz).
Abstract: Recently, increasing the quality of experience (QoE) is
an important issue. Since performance degradation at cell edge
extremely reduces the QoE, several techniques are defined at
LTE/LTE-A standard to remove inter-cell interference (ICI). However,
the conventional techniques have disadvantage because there is a
trade-off between resource allocation and reliable communication.
The proposed scheme reduces the ICI more efficiently by using
channel state information (CSI) smartly. It is shown that the proposed
scheme can reduce the ICI with fewer resources.
Abstract: Environmental impacts of six 3D printers using
various materials were compared to determine if material choice
drove sustainability, or if other factors such as machine type, machine
size, or machine utilization dominate. Cradle-to-grave life-cycle
assessments were performed, comparing a commercial-scale FDM
machine printing in ABS plastic, a desktop FDM machine printing in
ABS, a desktop FDM machine printing in PET and PLA plastics, a
polyjet machine printing in its proprietary polymer, an SLA machine
printing in its polymer, and an inkjet machine hacked to print in salt
and dextrose. All scenarios were scored using ReCiPe Endpoint H
methodology to combine multiple impact categories, comparing
environmental impacts per part made for several scenarios per
machine. Results showed that most printers’ ecological impacts were
dominated by electricity use, not materials, and the changes in
electricity use due to different plastics was not significant compared
to variation from one machine to another. Variation in machine idle
time determined impacts per part most strongly. However, material
impacts were quite important for the inkjet printer hacked to print in
salt: In its optimal scenario, it had up to 1/38th the impacts coreper
part as the worst-performing machine in the same scenario. If salt
parts were infused with epoxy to make them more physically robust,
then much of this advantage disappeared, and material impacts
actually dominated or equaled electricity use. Future studies should
also measure DMLS and SLS processes / materials.
Abstract: Strong anion exchange resins with QN+OH-, have the
potential to be developed and employed as heterogeneous catalyst for
transesterification, as they are chemically stable to leaching of the
functional group. Nine different SIERs (SIER1-9) with QN+OH-were
prepared by suspension polymerization of vinylbenzyl chloridedivinylbenzene
(VBC-DVB) copolymers in the presence of n-heptane
(pore-forming agent). The amine group was successfully grafted into
the polymeric resin beads through functionalization with
trimethylamine. These SIERs are then used as a catalyst for the
transesterification of triacetin with methanol. A set of differential
equations that represents the Langmuir-Hinshelwood-Hougen-
Watson (LHHW) and Eley-Rideal (ER) models for the
transesterification reaction were developed. These kinetic models of
LHHW and ER were fitted to the experimental data. Overall, the
synthesized ion exchange resin-catalyzed reaction were welldescribed
by the Eley-Rideal model compared to LHHW models,
with sum of square error (SSE) of 0.742 and 0.996, respectively.
Abstract: e-Service has moved from the usual manual and
traditional way of rendering services to electronic service provision
for the public and there are several reasons for implementing these
services, Airline ticketing have gone from its manual traditional way
to an intelligent web-driven service of purchasing. Many companies
have seen their profits doubled through the use of online services in
their operation and a typical example is Hewlett Packard (HP) which
is rapidly transforming their after sales business into a profit
generating e-service business unit.
This paper will examine the various challenges confronting e-
Service adoption and implementation in Nigeria and also analyse
lessons learnt from e-Service adoption and implementation in Asia to
see how it could be useful in Nigeria which is a lower middle income
country. From the analysis of the online survey data, it has been
identified that the public in Nigeria are much aware of e-Services but
successful adoption and implementation have been the problems
faced.