Abstract: Edge detection is usually the first step in medical
image processing. However, the difficulty increases when a
conventional kernel-based edge detector is applied to ultrasonic
images with a textural pattern and speckle noise. We designed an
adaptive diffusion filter to remove speckle noise while preserving the
initial edges detected by using a Sobel edge detector. We also propose
a genetic algorithm for edge selection to form complete boundaries of
the detected entities. We designed two fitness functions to evaluate
whether a criterion with a complex edge configuration can render a
better result than a simple criterion such as the strength of gradient.
The edges obtained by using a complex fitness function are thicker and
more fragmented than those obtained by using a simple fitness
function, suggesting that a complex edge selecting scheme is not
necessary for good edge detection in medical ultrasonic images;
instead, a proper noise-smoothing filter is the key.
Abstract: This paper explores the importance of privacy in a
contemporary online world. Crucial to the discussion is the idea of
the Lacanian postmodern fragmented self and the problem of how to
ensure that we have room to fully explore various aspects of our
personalities in an environment which is–or at least feels--safe and
free from observation by others. The paper begins with an
exploration of the idea of the self with particular regard to the ways
in which contemporary life and technology seems to have multiplied
the various faces or masks which we present in different contexts. A
brief history of privacy and surveillance follows. Finally, the paper
ends with an affirmation of the importance of private space as an
essential component of our spiritual and emotional well-being in
today-s wired world.
Abstract: Semantic query optimization consists in restricting the
search space in order to reduce the set of objects of interest for a
query. This paper presents an indexing method based on UB-trees
and a static analysis of the constraints associated to the views of the
database and to any constraint expressed on attributes. The result of
the static analysis is a partitioning of the object space into disjoint
blocks. Through Space Filling Curve (SFC) techniques, each
fragment (block) of the partition is assigned a unique identifier,
enabling the efficient indexing of fragments by UB-trees. The search
space corresponding to a range query is restricted to a subset of the
blocks of the partition. This approach has been developed in the
context of a KB-DBMS but it can be applied to any relational
system.
Abstract: Unlike the best effort service provided by the internet
today, next-generation wireless networks will support real-time
applications. This paper proposes an adaptive early packet discard
(AEPD) policy to improve the performance of the real time TCP
traffic over ATM networks and avoid the fragmentation problem.
Three main aspects are incorporated in the proposed policy. First,
providing quality-of-service (QoS) guaranteed for real-time
applications by implementing a priority scheduling. Second,
resolving the partially corrupted packets problem by differentiating
the buffered cells of one packet from another. Third, adapting a
threshold dynamically using Fuzzy logic based on the traffic
behavior to maintain a high throughput under a variety of load
conditions. The simulation is run for two priority classes of the input
traffic: real time and non-real time classes. Simulation results show
that the proposed AEPD policy improves throughput and fairness
over that using static threshold under the same traffic conditions.
Abstract: The gel-supported precipitation (GSP) process can be
used to make spherical particles (spherules) of nuclear fuel,
particularly for very high temperature reactors (VHTR) and even for
implementing the process called SPHEREPAC. In these different
cases, the main characteristics are the sphericity of the particles to be
manufactured and the control over their grain size. Nonetheless,
depending on the specifications defined for these spherical particles,
the GSP process has intrinsic limits, particularly when fabricating
very small particles. This paper describes the use of secondary
fragmentation (water, water/PVA and uranyl nitrate) on solid
surfaces under varying temperature and vibration conditions to assess
the relevance of using this new technique to manufacture very small
spherical particles by means of a modified GSP process. The
fragmentation mechanisms are monitored and analysed, before the
trends for its subsequent optimised application are described.
Abstract: The aim of this study was to examine the dynamics of functional composition of a non flooded Amazonian forest in response to drought stress in terms of diameter growth, recruitment and mortality. The survey was carried out in the continuous forest of the Biological dynamics of forest fragments project 90 km outside the city of Manaus, state of Amazonas Brazil. All stems >10 cm dbh where identified to species level and monitored in 18 one hectare permanent sample plots from 1981 to 2004.For statistical analysis all species where aggregated in three ecological guilds. Two distinct drought events occurred in 1983 and 1997. Results showed that more early successional species performed better than later successional ones. Response was significant for both events but for the 1997 event this was more pronounced possibly because of the fact that the event was in the middle of the dry rather than the wet period as was the 1983 one.
Abstract: Atherosclerosis was identified as a chronic inflammatory process resulting from interactions between plasma lipoproteins, cellular components (monocyte, macrophages, T lymphocytes, endothelial cells and smooth muscle cells) and the extracellular matrix of the arterial wall. Several types of genes were known to express during formation of atherosclerosis. This study is carried out to identify unknown differentially expressed gene (DEG) in atherogenesis. Rabbit’s aorta tissues were stained by H&E for histomorphology. GeneFishing™ PCR analysis was performed from total RNA extracted from the aorta tissues. The DNA fragment from DEG was cloned, sequenced and validated by Real-time PCR. Histomorphology showed intimal thickening in the aorta. DEG detected from ACP-41 was identified as cathepsin B gene and showed upregulation at week-8 and week-12 of atherogenesis. Therefore, ACP-based GeneFishing™ PCR facilitated identification of cathepsin B gene which was differentially expressed during development of atherosclerosis.
Abstract: The paper shows how the CASMAS modeling language,
and its associated pervasive computing architecture, can be
used to facilitate continuity of care by providing members of patientcentered
communities of care with a support to cooperation and
knowledge sharing through the usage of electronic documents and
digital devices. We consider a scenario of clearly fragmented care to
show how proper mechanisms can be defined to facilitate a better
integration of practices and information across heterogeneous care
networks. The scenario is declined in terms of architectural components
and cooperation-oriented mechanisms that make the support
reactive to the evolution of the context where these communities
operate.
Abstract: The paper shows some ability to manage two-phase
flows arising from the use of unsteady effects. In one case, we
consider the condition of fragmentation of the interface between the
two components leads to the intensification of mixing. The problem
is solved when the temporal and linear scale are small for the
appearance of the developed mixing layer. Showing that exist such
conditions for unsteady flow velocity at the surface of the channel,
which will lead to the creation and fragmentation of vortices at Re
numbers of order unity. Also showing that the Re is not a criterion of
similarity for this type of flows, but we can introduce a criterion that
depends on both the Re, and the frequency splitting of the vortices. It
turned out that feature of this situation is that streamlines behave
stable, and if we analyze the behavior of the interface between the
components it satisfies all the properties of unstable flows. The other
problem we consider the behavior of solid impurities in the extensive
system of channels. Simulated unsteady periodic flow modeled
breaths. Consider the behavior of the particles along the trajectories.
It is shown that, depending on the mass and diameter of the particles,
they can be collected in a caustic on the channel walls, stop in a
certain place or fly back. Of interest is the distribution of particle
velocity in frequency. It turned out that by choosing a behavior of the
velocity field of the carrier gas can affect the trajectory of individual
particles including force them to fly back.
Abstract: The purposes of this study are 1) to study the frequent
English writing errors of students registering the course: Reading and
Writing English for Academic Purposes II, and 2) to find out the
results of writing error correction by using coded indirect corrective
feedback and writing error treatments. Samples include 28 2nd year
English Major students, Faculty of Education, Suan Sunandha
Rajabhat University. Tool for experimental study includes the lesson
plan of the course; Reading and Writing English for Academic
Purposes II, and tool for data collection includes 4 writing tests of
short texts. The research findings disclose that frequent English
writing errors found in this course comprise 7 types of grammatical
errors, namely Fragment sentence, Subject-verb agreement, Wrong
form of verb tense, Singular or plural noun endings, Run-ons
sentence, Wrong form of verb pattern and Lack of parallel structure.
Moreover, it is found that the results of writing error correction by
using coded indirect corrective feedback and error treatment reveal
the overall reduction of the frequent English writing errors and the
increase of students’ achievement in the writing of short texts with
the significance at .05.
Abstract: The effects of irrigation with dairy factory wastewater
on soil properties were investigated at two sites that had received
irrigation for > 60 years. Two adjoining paired sites that had never
received DFE were also sampled as well as another seven fields from
a wider area around the factory. In comparison with paired sites that
had not received effluent, long-term wastewater irrigation resulted in
an increase in pH, EC, extractable P, exchangeable Na and K and
ESP. These changes were related to the use of phosphoric acid,
NaOH and KOH as cleaning agents in the factory. Soil organic C
content was unaffected by DFE irrigation but the size (microbial
biomass C and N) and activity (basal respiration) of the soil
microbial community were increased. These increases were
attributed to regular inputs of soluble C (e.g. lactose) present as milk
residues in the wastewater. Principal component analysis (PCA) of
the soils data from all 11sites confirmed that the main effects of DFE
irrigation were an increase in exchangeable Na, extractable P and
microbial biomass C, an accumulation of soluble salts and a liming
effect. PCA analysis of soil bacterial community structure, using
PCR-DGGE of 16S rDNA fragments, generally separated individual
sites from one another but did not group them according to irrigation
history. Thus, whilst the size and activity of the soil microbial
community were increased, the structure and diversity of the
bacterial community remained unaffected.
Abstract: In this paper we study different similarity based approaches for the development of QSAR model devoted to the prediction of activity of antiobesity drugs. Classical similarity approaches are compared regarding to dissimilarity models based on the consideration of the calculation of Euclidean distances between the nonisomorphic fragments extracted in the matching process. Combining the classical similarity and dissimilarity approaches into a new similarity measure, the Approximate Similarity was also studied, and better results were obtained. The application of the proposed method to the development of quantitative structure-activity relationships (QSAR) has provided reliable tools for predicting of inhibitory activity of drugs. Acceptable results were obtained for the models presented here.
Abstract: Alpfa-fetoprotein and its fragments may be an important vehicle for targeted delivery of radionuclides to the tumor. We investigated the effect of conditions on the labeling of biologically active synthetic peptide based on the (F-afp) with technetium-99m. The influence of the nature of the buffer solution, pH, concentration of reductant, concentration of the peptide and the reaction temperature on the yield of labeling was examined. As a result, the following optimal conditions for labeling of (F-afp) are found: pH 8.5 (phosphate and bicarbonate buffers) and pH from 1.7 to 7.0 (citrate buffer). The reaction proceeds with sufficient yield at room temperature for 30 min at the concentration of SnCl2 and (Fafp) (F-afp) is to be less than 10 mkg/ml and 25 mkg/ml, respectively. Investigations of the test drug accumulation in the tumor cells of human breast cancer were carried out. Results can be assumed that the in vivo study of the (F-afp) in experimental tumor lesions will show concentrations sufficient for imaging these lesions by SPECT.
Abstract: Bean common mosaic necrosis virus (BCMNV) is a
potyvirus with a worldwide distribution. This virus causes serious
economic losses in Iran in many leguminoses. During 20008,
samples were collected from soybeans fields in Tehran Province.
Four isolates (S1, S2 and S3) were inoculated on 15 species of
Cucurbitaceae, Chenopodiaceae, Solanacae and Leguminosae.
Chenopodium quinoa and C. amaranticolor.
Did not developed any symptoms.all isolates caused mosaic
symptoms on Phaseolus vulgaris cv. Red Kidney and P. vulgaris cv.
Bountiful. The molecular weights of coat protein using SDS-PAGE
and western blotting were estimated at 33 kDa. Reverse transcription
polymerase chain reaction (RT-PCR) was performed using one
primer pairs designed by L. XU et al. An approximately 920 bp
fragment was amplified with a specific primer.
Abstract: This paper presents a novel algorithm for path planning of mobile robots in known 3D environments using Binary Integer Programming (BIP). In this approach the problem of path planning is formulated as a BIP with variables taken from 3D Delaunay Triangulation of the Free Configuration Space and solved to obtain an optimal channel made of connected tetrahedrons. The 3D channel is then partitioned into convex fragments which are used to build safe and short paths within from Start to Goal. The algorithm is simple, complete, does not suffer from local minima, and is applicable to different workspaces with convex and concave polyhedral obstacles. The noticeable feature of this algorithm is that it is simply extendable to n-D Configuration spaces.
Abstract: To distinguish small retinal hemorrhages in early
diabetic retinopathy from dust artifacts, we analyzed hue, lightness,
and saturation (HLS) color spaces. The fundus of 5 patients with
diabetic retinopathy was photographed. For the initial experiment, we
placed 4 different colored papers on the ceiling of a darkroom. Using
each color, 10 fragments of house dust particles on a magnifier were
photographed. The colored papers were removed, and 3 different
colored light bulbs were suspended from the ceiling. Ten fragments of
house dust particles on the camera-s object lens were photographed.
We then constructed an experimental device that can photograph
artificial eyes. Five fragments of house dust particles under the ocher
fundus of the artificial eye were photographed. On analyzing HLS
color space of the dust artifact, lightness and saturation were found to
be highly sensitive. However, hue was not highly sensitive.
Abstract: The aim of this work was to detect genetic variability among the set of 40 castor genotypes using 8 RAPD markers. Amplification of genomic DNA of 40 genotypes, using RAPD analysis, yielded in 66 fragments, with an average of 8.25 polymorphic fragments per primer. Number of amplified fragments ranged from 3 to 13, with the size of amplicons ranging from 100 to 1200 bp. Values of the polymorphic information content (PIC) value ranged from 0.556 to 0.895 with an average of 0.784 and diversity index (DI) value ranged from 0.621 to 0.896 with an average of 0.798. The dendrogram based on hierarchical cluster analysis using UPGMA algorithm was prepared and analyzed genotypes were grouped into two main clusters and only two genotypes could not be distinguished. Knowledge on the genetic diversity of castor can be used for future breeding programs for increased oil production for industrial uses.
Abstract: Gamboge disorder (GD) or fruit damage by the yellow sap is a major problem in mangosteen. Mangosteen plants varied in the level of GD, from very low or non GD to low, moderate and high GD. However it was difficult to differentiate between GD and non GD plants because evaluation of the disorder is strongly influenced by environment. In this study we investigated the usefulness of primer designed from bioinformatics related to cell wall strength, termed as MCWS, to predict GD. Plant materials used were 28 mangosteen plants selected based on percentage of GD categorized as high, moderate, low and very low or non GD. The result showed that the specific DNA fragments were absent in the high GD accessions. The MCWS marker suggests as a novel polymorphic marker for GD in mangosteen as well as a marker for detect variability in mangosteen as apomictic plant.
Abstract: Transcription factor p53 has a powerful tumor
suppressing function that is associated with many cancers. However,
p53 of the molecular weight was higher make the limitation across to
skin or cell membrane. Thymidine dinucleotide (pTT), an
oligonucleotide, can activate the p53 transcription factor. pTT is a
hydrophilic and negative charge oligonucleotide, which delivery in to
cell membrane need an appropriate carrier. The aim of this study was
to improve the bioavailability of the nucleotide fragment, thymidine
dinucleotide (pTT), using elasic liposome carriers to deliver the drug
into the skin. The study demonstrate that dioleoylphosphocholine
(DOPC) incorporated with sodium cholate at molar ratio 1:1 can
archived the particle size about 220 nm. This elastic liposome could
penetration through skin from stratum corneum to whole epidermis by
confocal laser scanning microscopy (CLSM). Moreover, we observed
the the slight increase in generation of p53 by western blot.
Abstract: Matrix metalloproteinase-3 (MMP3) is key member
of the MMP family, and is known to be present in coronary
atherosclerotic. Several studies have demonstrated that MMP-3
5A/6A polymorphism modify each transcriptional activity in allele
specific manner. We hypothesized that this polymorphism may play
a role as risk factor for development of coronary stenosis. The aim of
our study was to estimate MMP-3 (5A/6A) gene polymorphism on
interindividual variability in risk for coronary stenosis in an Iranian
population.DNA was extracted from white blood cells and genotypes
were obtained from coronary stenosis cases (n=95) and controls
(n=100) by PCR (polymerase chain reaction) and restriction
fragment length polymorphism techniques. Significant differences
between cases and controls were observed for MMP3 genotype
frequencies (X2=199.305, p< 0.001); the 6A allele was less
frequently seen in the control group, compared to the disease group
(85.79 vs. 78%, 6A/6A+5A/6A vs. 5A/5A, P≤0.001). These data
imply the involvement of -1612 5A/6A polymorphism in coronary
stenosis, and suggest that probably the 6A/6A MMP-3 genotype is a
genetic susceptibility factor for coronary stenosis.