Abstract: In-core memory requirement is a bottleneck in solving
large three dimensional Navier-Stokes finite element problem
formulations using sparse direct solvers. Out-of-core solution
strategy is a viable alternative to reduce the in-core memory
requirements while solving large scale problems. This study
evaluates the performance of various out-of-core sequential solvers
based on multifrontal or supernodal techniques in the context of
finite element formulations for three dimensional problems on a
Windows platform. Here three different solvers, HSL_MA78,
MUMPS and PARDISO are compared. The performance of these
solvers is evaluated on a 64-bit machine with 16GB RAM for finite
element formulation of flow through a rectangular channel. It is
observed that using out-of-core PARDISO solver, relatively large
problems can be solved. The implementation of Newton and
modified Newton's iteration is also discussed.
Abstract: In this paper, Fabless Prototyping Methodology is
introduced for the design and analysis of MEMS devices.
Conventionally Finite Element Analysis (FEA) is performed before
system level simulation. In our proposed methodology, system level
simulation is performed earlier than FEA as it is computationally less
extensive and low cost. System level simulations are based on
equivalent behavioral models of MEMS device. Electrostatic
actuation based MEMS Microgripper is chosen as case study to
implement this methodology. This paper addresses the behavioral
model development and simulation of actuator part of an
electrostatically actuated Microgripper. Simulation results show that
the actuator part of Microgripper works efficiently for a voltage range
of 0-45V with the corresponding jaw displacement of 0-4.5425μm.
With some minor changes in design, this range can be enhanced to
15μm at 85V.
Abstract: MMR vaccine failure had been reported globally and
here we report that it occurs now in India. Samples were collected from clinically suspected mumps cases were subjected for anti
mumps antibodies, virus isolation, RT-PCR, sequencing and
phylogenetic tree analysis. 56 samples collected from men and women belonging to various age groups. 30 had been vaccinated and
the status of 26 patients was unknown. 28 out of 30 samples were
found to be symptomatic and positive for Mumps IgM, indicating
active mumps infection in 93.4% of the vaccinated population. A
phylogenetic tree comparison of the clinical isolate is shown to be genotype C which is distinct from vaccine strain. Our study clearly sending warning signs that MMR vaccine is a failure and it needs to be revamped for the human use by increasing its efficacy and efficiency.