Scholarly

A Novel Nucleus-Based Classifier for Discrimination of Osteoclasts and Mesenchymal Precursor Cells in Mouse Bone Marrow Cultures

Year: 2012 Volume: 6 Issue: 7 286 - 291 Pages

Abstract: Bone remodeling occurs by the balanced action of bone resorbing osteoclasts (OC) and bone-building osteoblasts. Increased bone resorption by excessive OC activity contributes to malignant and non-malignant diseases including osteoporosis. To study OC differentiation and function, OC formed in in vitro cultures are currently counted manually, a tedious procedure which is prone to inter-observer differences. Aiming for an automated OC-quantification system, classification of OC and precursor cells was done on fluorescence microscope images based on the distinct appearance of fluorescent nuclei. Following ellipse fitting to nuclei, a combination of eight features enabled clustering of OC and precursor cell nuclei. After evaluating different machine-learning techniques, LOGREG achieved 74% correctly classified OC and precursor cell nuclei, outperforming human experts (best expert: 55%). In combination with the automated detection of total cell areas, this system allows to measure various cell parameters and most importantly to quantify proteins involved in osteoclastogenesis.

Infrared Lamp Array Simulation Technology Used during Satellite Thermal Testing

Year: 2010 Volume: 4 Issue: 9 770 - 772 Pages

Abstract: A satellite is being integrated and tested by BISEE (Beijing Institute of Spacecraft Environment Engineering). This paper describes the infrared lamp array simulation technology used for satellite thermal balance and thermal vacuum test. These tests were performed in KM6 space environmental simulator in Beijing, China. New software and hardware developed by BISEE, along with enhanced heat flux uniformity, provided for well accomplished thermal balance and thermal vacuum tests. The flux uniformity of lamp array was satisfied with test requirement. Monitored background radiometer offered reliable heat flux measurements with remarkable repeatability. Simulation software supplied accurate thermal flux distribution predictions.

Preparation a Study on the Use of the Resident Registration Number and Alternatives for RRN

Year: 2012 Volume: 6 Issue: 11 2738 - 2741 Pages

Abstract: The resident registration number was adopted for the purposes of enhanced services for resident convenience and effective performance of governmental administrative affairs. However, it has been used for identification purposes customarily and irrationally in line with the development and spread of the Internet. In response to the growing concern about the leakage of collected RRNs and possible abuses of stolen RRNs, e.g. identity theft, for crimes, the Korean Communications Commission began to take legal/regulatory actions in 2011 to minimize the online collection and use of resident registration numbers. As the use of the RRN was limited after the revision of the Act on Promotion of Information and Communications Network Utilization and Information Protection, etc., online business providers were required to have alternatives to the RRN for the purpose of identifying the user's identity and age, in compliance with the law, and settling disputes with customers. This paper presents means of verifying the personal identity by taking advantage of the commonly used infrastructure and simply replacing personal information entered and stored, without requiring users to enter their RRNs.

A Software for Calculation of Optimum Conditions for Cotton Bobbin Drying in a Hot-Air Bobbin Dryer

Year: 2011 Volume: 5 Issue: 6 942 - 946 Pages

Abstract: In this study, a software has been developed to predict the optimum conditions for drying of cotton based yarn bobbins in a hot air dryer. For this purpose, firstly, a suitable drying model has been specified using experimental drying behavior for different values of drying parameters. Drying parameters in the experiments were drying temperature, drying pressure, and volumetric flow rate of drying air. After obtaining a suitable drying model, additional curve fittings have been performed to obtain equations for drying time and energy consumption taking into account the effects of drying parameters. Then, a software has been developed using Visual Basic programming language to predict the optimum drying conditions for drying time and energy consumption.

Factors Influencing B2c eCommerce Diffusion

Year: 2012 Volume: 6 Issue: 5 727 - 735 Pages

Abstract: Despite the fact that B2c eCommerce has become important in numerous economies, its adoption varies from country to country. This paper aims to identify the factors affecting (enabling or inhibiting) B2c eCommerce and to determine their quantitative impact on the diffusion of online sales across countries. A dynamic panel model analyzing the relationship between 13 factors (Macroeconomic, Demographic, Socio-Cultural, Infrastructural and Offer related) stemming from a complete literature analysis and the B2c eCommerce value in 45 countries over 9 years has been developed. Having a positive correlation coefficient, GDP, mobile penetration, Internet user penetration and credit card penetration resulted as enabling drivers of the B2c eCommerce value across countries, whereas, having a negative correlation coefficient,equal distribution of income and the development of traditional retailing network act as inhibiting factors.

Towards Synthesis of Atropodiastereomeric Indolostilbenes Hybrids: A New Class of Oligostilbenoids

Year: 2013 Volume: 7 Issue: 12 884 - 892 Pages

Abstract: The conceptually construction of axially chiral indolostilbenesi.eN-(2-{(E)-2-[2'-(1-Acetyl-1H-indol-2-yl)-3'chloro-4,4',6,6'-tetramethoxy[1,1'-biphenyl]-2yl]ethenyl}phenyl)acetamide and N-(2-{(E)-2-[2'-(1-Acetyl-1H-indol-2-yl)-3'-chloro-2,4',6,6'-tetramethoxy[1,1'-biphenyl]-4-yl]ethenyl}phenyl) acetamide are described in this paper. These structure, were obtained by the tactical combination of palladium-catalyzed coupling which produced 10-acetamido-3,5-dimethoxystilbene, follow by FeCl3-induced oxidative cyclization/dimerisation. All structures were unambiguously confirmed by 1D (1H, 13C) and 2D NMR experiment, (COSY, HMQC, HMBC) and mass spectrometry.

Simultaneous HPAM/SDS Injection in Heterogeneous/Layered Models

Year: 2013 Volume: 7 Issue: 6 310 - 313 Pages

Abstract: Although lots of experiments have been done in enhanced oil recovery, the number of experiments which consider the effects of local and global heterogeneity on efficiency of enhanced oil recovery based on the polymer-surfactant flooding is low and rarely done. In this research, we have done numerous experiments of water flooding and polymer-surfactant flooding on a five spot glass micromodel in different conditions such as different positions of layers. In these experiments, five different micromodels with three different pore structures are designed. Three models with different layer orientation, one homogenous model and one heterogeneous model are designed. In order to import the effect of heterogeneity of porous media, three types of pore structures are distributed accidentally and with equal ratio throughout heterogeneous micromodel network according to random normal distribution. The results show that maximum EOR recovery factor will happen in a situation where the layers are orthogonal to the path of mainstream and the minimum EOR recovery factor will happen in a situation where the model is heterogeneous. This experiments show that in polymer-surfactant flooding, with increase of angles of layers the EOR recovery factor will increase and this recovery factor is strongly affected by local heterogeneity around the injection zone.

Urban Floods and Importance of Them in Cities Security Planning (Case Study: Dominant Watershed on Zavvareh City)

Year: 2008 Volume: 2 Issue: 7 703 - 707 Pages

Abstract: Development of cities and villages, agricultural farms and industrial regions in abutment and/or in the course of streams and rivers or in prone flood lands has been caused more notations in hydrology problems and city planning topics. In order to protection of cities against of flood damages, embankment construction is a desired and scientific method. The cities that located in arid zones may damage by floods periodically. Zavvareh city in Ardestan township(Isfahan province) with 7704 people located in Ardestan plain that has been damaged by floods that have flowed from dominant mountainous watersheds in past years with regard to return period. In this study, according to flowed floods toward Zavvareh city, was attempt to plan suitable hydraulic structures such as canals, bridges and collectors in order to collection, conduction and depletion of city surface runoff.

3D CAD Models and its Feature Similarity

Year: 2009 Volume: 3 Issue: 2 241 - 245 Pages

Abstract: Knowing the geometrical object pose of products in manufacturing line before robot manipulation is required and less time consuming for overall shape measurement. In order to perform it, the information of shape representation and matching of objects is become required. Objects are compared with its descriptor that conceptually subtracted from each other to form scalar metric. When the metric value is smaller, the object is considered closed to each other. Rotating the object from static pose in some direction introduce the change of value in scalar metric value of boundary information after feature extraction of related object. In this paper, a proposal method for indexing technique for retrieval of 3D geometrical models based on similarity between boundaries shapes in order to measure 3D CAD object pose using object shape feature matching for Computer Aided Testing (CAT) system in production line is proposed. In experimental results shows the effectiveness of proposed method.

Experimental Design and Performance Analysis in Plasma Arc Surface Hardening

Year: 2011 Volume: 5 Issue: 8 648 - 654 Pages

Abstract: In this paper, the experimental design of using the Taguchi method is employed to optimize the processing parameters in the plasma arc surface hardening process. The processing parameters evaluated are arc current, scanning velocity and carbon content of steel. In addition, other significant effects such as the relation between processing parameters are also investigated. An orthogonal array, signal-to-noise (S/N) ratio and analysis of variance (ANOVA) are employed to investigate the effects of these processing parameters. Through this study, not only the hardened depth increased and surface roughness improved, but also the parameters that significantly affect the hardening performance are identified. Experimental results are provided to verify the effectiveness of this approach.

Consideration of Criteria of Vibration Comfort of People in Diagnosis and Design of Buildings

Year: 2011 Volume: 5 Issue: 11 516 - 522 Pages

Abstract: The increasing influence of traffic on building objects and people residing in them should be taken into account in diagnosis and design. Users of buildings expect that vibrations occurring in their environment, will not only lead to damage to the building or its accelerated wear, but neither would affect the required comfort in rooms designed to accommodate people. This article describes the methods and principles useful in designing and building diagnostics located near transportation routes, with particular emphasis on the impact of traffic vibration on people in buildings. It also describes the procedures used in obtaining information about the parameters of vibrations in different cases of diagnostics and design. A universal algorithm of procedure in diagnostics and design of buildings taking into account assurance of human vibration comfort of people residing in the these buildings was presented.

Performance Analysis of MIMO Based Multi-User Cooperation Diversity Over Various Fading Channels

Year: 2010 Volume: 4 Issue: 2 224 - 229 Pages

Abstract: In this paper, hybrid FDMA-TDMA access technique in a cooperative distributive fashion introducing and implementing a modified protocol introduced in [1] is analyzed termed as Power and Cooperation Diversity Gain Protocol (PCDGP). A wireless network consists of two users terminal , two relays and a destination terminal equipped with two antennas. The relays are operating in amplify-and-forward (AF) mode with a fixed gain. Two operating modes: cooperation-gain mode and powergain mode are exploited from source terminals to relays, as it is working in a best channel selection scheme. Vertical BLAST (Bell Laboratories Layered Space Time) or V-BLAST with minimum mean square error (MMSE) nulling is used at the relays to perfectly detect the joint signals from multiple source terminals. The performance is analyzed using binary phase shift keying (BPSK) modulation scheme and investigated over independent and identical (i.i.d) Rayleigh, Ricean-K and Nakagami-m fading environments. Subsequently, simulation results show that the proposed scheme can provide better signal quality of uplink users in a cooperative communication system using hybrid FDMATDMA technique.

The Impact of Germination and In Vitro Digestion on the Formation of Angiotensin Converting Enzyme (ACE) Inhibitory Peptides from Lentil Proteins Compared to Whey Proteins

Year: 2009 Volume: 3 Issue: 1 1 - 11 Pages

Abstract: Biologically active peptides are of particular interest in food science and human nutrition because they have been shown to play several physiological roles. In vitro gastrointestinal digestion of lentil and whey proteins in this study produced high angiotensin-I converting enzyme inhibitory activity with 75.5±1.9 and 91.4±2.3% inhibition, respectively. High ACE inhibitory activity was observed in lentil after 5 days of germination (84.3±1.2%). Fractionation by reverse phase chromatography gave inhibitory activities as high as 86.3±2.0 for lentil, 94.8±1.8% for whey and 93.7±1.7% at 5th day of germination. Further purification by HPLC resulted in several inhibitory peptides with IC50 values ranging from 0.064 to 0.164 mg/ml. These results demonstrate that lentil proteins are a good source of peptides with ACE inhibitory activity that can be released by germination or gastrointestinal digestion. Despite the lower bioactivity in comparison with whey proteins, incorporation of lentil proteins in functional food formulations and natural drugs look promising.

Project Selection by Using a Fuzzy TOPSIS Technique

Year: 2008 Volume: 2 Issue: 4 375 - 380 Pages

Abstract: Selection of a project among a set of possible alternatives is a difficult task that the decision maker (DM) has to face. In this paper, by using a fuzzy TOPSIS technique we propose a new method for a project selection problem. After reviewing four common methods of comparing investment alternatives (net present value, rate of return, benefit cost analysis and payback period) we use them as criteria in a TOPSIS technique. First we calculate the weight of each criterion by a pairwise comparison and then we utilize the improved TOPSIS assessment for the project selection.

Closed form Delay Model for on-Chip VLSIRLCG Interconnects for Ramp Input for Different Damping Conditions

Year: 2011 Volume: 5 Issue: 3 225 - 231 Pages

Abstract: Fast delay estimation methods, as opposed to simulation techniques, are needed for incremental performance driven layout synthesis. On-chip inductive effects are becoming predominant in deep submicron interconnects due to increasing clock speed and circuit complexity. Inductance causes noise in signal waveforms, which can adversely affect the performance of the circuit and signal integrity. Several approaches have been put forward which consider the inductance for on-chip interconnect modelling. But for even much higher frequency, of the order of few GHz, the shunt dielectric lossy component has become comparable to that of other electrical parameters for high speed VLSI design. In order to cope up with this effect, on-chip interconnect has to be modelled as distributed RLCG line. Elmore delay based methods, although efficient, cannot accurately estimate the delay for RLCG interconnect line. In this paper, an accurate analytical delay model has been derived, based on first and second moments of RLCG interconnection lines. The proposed model considers both the effect of inductance and conductance matrices. We have performed the simulation in 0.18μm technology node and an error of as low as less as 5% has been achieved with the proposed model when compared to SPICE. The importance of the conductance matrices in interconnect modelling has also been discussed and it is shown that if G is neglected for interconnect line modelling, then it will result an delay error of as high as 6% when compared to SPICE.

Characterization of Microroughness Parameters in Cu and Cu2O Nanoparticles Embedded in Carbon Film

Year: 2011 Volume: 5 Issue: 4 243 - 246 Pages

Abstract: The morphological parameter of a thin film surface can be characterized by power spectral density (PSD) functions which provides a better description to the topography than the RMS roughness and imparts several useful information of the surface including fractal and superstructure contributions. Through the present study Nanoparticle copper/carbon composite films were prepared by co-deposition of RF-Sputtering and RF-PECVD method from acetylene gas and copper target. Surface morphology of thin films is characterized by using atomic force microscopy (AFM). The Carbon content of our films was obtained by Rutherford Back Scattering (RBS) and it varied from .4% to 78%. The power values of power spectral density (PSD) for the AFM data were determined by the fast Fourier transform (FFT) algorithms. We investigate the effect of carbon on the roughness of thin films surface. Using such information, roughness contributions of the surface have been successfully extracted.

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