Abstract: In this paper we study different similarity based approaches for the development of QSAR model devoted to the prediction of activity of antiobesity drugs. Classical similarity approaches are compared regarding to dissimilarity models based on the consideration of the calculation of Euclidean distances between the nonisomorphic fragments extracted in the matching process. Combining the classical similarity and dissimilarity approaches into a new similarity measure, the Approximate Similarity was also studied, and better results were obtained. The application of the proposed method to the development of quantitative structure-activity relationships (QSAR) has provided reliable tools for predicting of inhibitory activity of drugs. Acceptable results were obtained for the models presented here.
Abstract: In this paper we present a statistical analysis of Voice
over IP (VoIP) packet streams produced by the G.711 voice coder
with voice activity detection (VAD). During telephone conversation,
depending whether the interlocutor speaks (ON) or remains silent
(OFF), packets are produced or not by a voice coder. As index of
dispersion for both ON and OFF times distribution was greater than
one, we used hyperexponential distribution for approximation of
streams duration. For each stage of the hyperexponential distribution,
we tested goodness of our fits using graphical methods, we calculated
estimation errors, and performed Kolmogorov-Smirnov test.
Obtained results showed that the precise VoIP source model can be
based on the five-state Markov process.
Abstract: Cities denote instantaneously a challenge and an
opportunity for climate change policy. Cities are the place where
most energy services are needed because urbanization is closely
linked to high population densities and concentration of economic
activities and production (Urban energy demand). Consequently, it is
critical to explain about the role of cities within the world-s energy
systems and its correlation with the climate change issue. With more
than half of the world-s population already living in urban areas, and
that percentage expected to rise to 75 per cent by 2050, it is clear that
the path to sustainable development must pass through cities. Cities
expanding in size and population pose increased challenges to the
environment, of which energy is part as a natural resource, and to the
quality of life. Nowadays, most cities have already understood the
importance of sustainability, both at their local scale as in terms of
their contribution to sustainability at higher geographical scales. It
requires the perception of a city as a complex and dynamic
ecosystem, an open system, or cluster of systems, where the energy
as well as the other natural resources is transformed to satisfy the
needs of the different urban activities. In fact, buildings and
transportation generally represent most of cities direct energy
demand, i.e., between 60 per cent and 80 per cent of the overall
consumption. Buildings, both residential and services are usually
influenced by the local physical and social conditions. In terms of
transport, the energy demand is also strongly linked with the specific
characteristics of a city (urban mobility).The concept of a “smart
city" builds on statistics as seven key axes of a city-s success in
moving towards common platform (brain nerve)of sustainable urban
energy systems.
With the aforesaid knowledge, the authors have suggested a frame
work to role of cities, as energy actors for smart city management.
The authors have discusses the potential elements needed for energy
in smart cities and also identified potential energy actions and
relevant barriers. Furthermore, three levels of city smartness in cities
actions to overcome market /institutional failures with a local
approach are distinguished. The authors have made an attempt to
conceive and implement concepts of city smartness by adopting the
city or local government as nerve center through an integrated
planning approach. Finally, concluding with recommendations for
the organization of the Smart Sustainable Cities for positive changes
of urban India.
Abstract: There is a growing interest in the food industry and in preventive health care for the development and evaluation of natural antioxidants from medicinal plant materials. In the present work, extracts of three medicinal plants (Tilia argentea, Crataegi folium leaves and Polygonum bistorta roots) used in Turkish phytotheraphy were screened for their phenolic profiles and antioxidant properties. Crude extracts were obtained from different parts of plants, by solidliquid extraction with pure water, 70% acetone and 70% methanol aqueous solvents. The antioxidant activity of the extracts was determined by ABTS.+ radical cation scavenging activity. The Folin Ciocalteu procedure was used to assess the total phenolic concentrations of the extracts as gallic acid equivalents. A modified liquid chromatography-electro spray ionization-mass spectrometry (LC-ESI-MS) was used to obtain chromatographic profiles of the phenolic compounds in the medicinal plants. The predominant phenolic compounds detected in different extracts of the plants were catechin, protocatechuic and chlorogenic acids. The highest phenolic contents were obtained by using 70% acetone as aqueous solvent, whereas the lowest phenolic contents were obtained by water extraction due to Folin Ciocalteu results. The results indicate that acetone extracts of Tilia argentea had the highest antioxidant capacity as free ABTS radical scavengers. The lowest phenolic contents and antioxidant capacities were obtained from Polygonum bistorta root extracts.
Abstract: This paper reviews the major contributions to the Motion Planning (MP) field throughout a 35-year period, from classic approaches to heuristic algorithms. Due to the NP-Hardness of the MP problem, heuristic methods have outperformed the classic approaches and have gained wide popularity. After surveying around 1400 papers in the field, the amount of existing works for each method is identified and classified. Especially, the history and applications of numerous heuristic methods in MP is investigated. The paper concludes with comparative tables and graphs demonstrating the frequency of each MP method's application, and so can be used as a guideline for MP researchers.
Abstract: Hair is a non homogenous complex material which
can be associated with a polymer. It is made up 95% of Keratin.
Hair has a great social significance for human beings. In the High
Middle Ages, for example, long hairs have been reserved for kings
and nobles.
Most common interest in hair is focused on hair growth, hair types
and hair care, but hair is also an important biomaterial which can
vary depending on ethnic origin or on age, hair colour for example
can be a sign of ethnic ancestry or age (dark hair for Asiatic, blond
hair for Caucasian and white hair for old people in general).
In this context, different approaches have been conducted to
determine the differences in mechanical properties and characterize
the fracture topography at the surface of hair depending on its type
and its age.
A tensile testing machine was especially designed to achieve
tensile tests on hair. This device is composed of a microdisplacement
system and a force sensor whose peak load is limited to
3N. The curves and the values extracted from each experiment, allow
us to compare the evolution of the mechanical properties from one
hair to another.
Observations with a Scanning Electron Microscope (SEM) and
with an interferometer were made on different hairs. Thus, it is
possible to access the cuticle state and the fracture topography for
each category.
Abstract: An induced graphoidal cover of a graph G is a collection ψ of (not necessarily open) paths in G such that every path in ψ has at least two vertices, every vertex of G is an internal vertex of at most one path in ψ, every edge of G is in exactly one path in ψ and every member of ψ is an induced cycle or an induced path. The minimum cardinality of an induced graphoidal cover of G is called the induced graphoidal covering number of G and is denoted by ηi(G) or ηi. Here we find induced graphoidal cover for some classes of graphs.
Abstract: In this paper, the effects of radiation, chemical
reaction and double dispersion on mixed convection heat and mass
transfer along a semi vertical plate are considered. The plate is
embedded in a Newtonian fluid saturated non - Darcy (Forchheimer
flow model) porous medium. The Forchheimer extension and first
order chemical reaction are considered in the flow equations. The
governing sets of partial differential equations are nondimensionalized
and reduced to a set of ordinary differential
equations which are then solved numerically by Fourth order Runge–
Kutta method. Numerical results for the detail of the velocity,
temperature, and concentration profiles as well as heat transfer rates
(Nusselt number) and mass transfer rates (Sherwood number) against
various parameters are presented in graphs. The obtained results are
checked against previously published work for special cases of the
problem and are found to be in good agreement.
Abstract: Location selection is one of the most important
decision making process which requires to consider several criteria
based on the mission and the strategy. This study-s object is to
provide a decision support model in order to help the bank selecting
the most appropriate location for a bank-s branch considering a case
study in Turkey. The object of the bank is to select the most
appropriate city for opening a branch among six alternatives in the
South-Eastern of Turkey. The model in this study was consisted of
five main criteria which are Demographic, Socio-Economic, Sectoral
Employment, Banking and Trade Potential and twenty one subcriteria
which represent the bank-s mission and strategy. Because of
the multi-criteria structure of the problem and the fuzziness in the
comparisons of the criteria, fuzzy AHP is used and for the ranking of
the alternatives, TOPSIS method is used.
Abstract: In this paper, the construction of a detailed spine
model is presented using the LifeMOD Biomechanics Modeler. The
detailed spine model is obtained by refining spine segments in
cervical, thoracic and lumbar regions into individual vertebra
segments, using bushing elements representing the intervertebral
discs, and building various ligamentous soft tissues between
vertebrae. In the sagittal plane of the spine, constant force will be
applied from the posterior to anterior during simulation to determine
dynamic characteristics of the spine. The force magnitude is
gradually increased in subsequent simulations. Based on these
recorded dynamic properties, graphs of displacement-force
relationships will be established in terms of polynomial functions by
using the least-squares method and imported into a haptic integrated
graphic environment. A thoracolumbar spine model with complex
geometry of vertebrae, which is digitized from a resin spine
prototype, will be utilized in this environment. By using the haptic
technique, surgeons can touch as well as apply forces to the spine
model through haptic devices to observe the locomotion of the spine
which is computed from the displacement-force relationship graphs.
This current study provides a preliminary picture of our ongoing
work towards building and simulating bio-fidelity scoliotic spine
models in a haptic integrated graphic environment whose dynamic
properties are obtained from LifeMOD. These models can be helpful
for surgeons to examine kinematic behaviors of scoliotic spines and
to propose possible surgical plans before spine correction operations.
Abstract: With the development of ubiquitous computing,
current user interaction approaches with keyboard, mouse and pen
are not sufficient. Due to the limitation of these devices the useable
command set is also limited. Direct use of hands as an input device is
an attractive method for providing natural Human Computer
Interaction which has evolved from text-based interfaces through 2D
graphical-based interfaces, multimedia-supported interfaces, to fully
fledged multi-participant Virtual Environment (VE) systems.
Imagine the human-computer interaction of the future: A 3Dapplication
where you can move and rotate objects simply by moving
and rotating your hand - all without touching any input device. In this
paper a review of vision based hand gesture recognition is presented.
The existing approaches are categorized into 3D model based
approaches and appearance based approaches, highlighting their
advantages and shortcomings and identifying the open issues.
Abstract: The study of proteomics reached unexpected levels of
interest, as a direct consequence of its discovered influence over some
complex biological phenomena, such as problematic diseases like
cancer. This paper presents the latest authors- achievements regarding
the analysis of the networks of proteins (interactome networks), by
computing more efficiently the betweenness centrality measure. The
paper introduces the concept of betweenness centrality, and then
describes how betweenness computation can help the interactome net-
work analysis. Current sequential implementations for the between-
ness computation do not perform satisfactory in terms of execution
times. The paper-s main contribution is centered towards introducing
a speedup technique for the betweenness computation, based on
modified shortest path algorithms for sparse graphs. Three optimized
generic algorithms for betweenness computation are described and
implemented, and their performance tested against real biological
data, which is part of the IntAct dataset.
Abstract: The Petri net tool INA is a well known tool by the
Petri net community. However, it lacks a graphical environment to
cerate and analyse INA models. Building a modelling tool for the
design and analysis from scratch (for INA tool for example) is
generally a prohibitive task. Meta-Modelling approach is useful to
deal with such problems since it allows the modelling of the
formalisms themselves. In this paper, we propose an approach based
on the combined use of Meta-modelling and Graph Grammars to
automatically generate a visual modelling tool for INA for analysis
purposes. In our approach, the UML Class diagram formalism is
used to define a meta-model of INA models. The meta-modelling
tool ATOM3 is used to generate a visual modelling tool according to
the proposed INA meta-model. We have also proposed a graph
grammar to automatically generate INA description of the
graphically specified Petri net models. This allows the user to avoid
the errors when this description is done manually. Then the INA tool
is used to perform the simulation and the analysis of the resulted INA
description. Our environment is illustrated through an example.
Abstract: The Yasuj city stream named the Beshar supply
water for different usages such as aquaculture farms , drinking,
agricultural and industrial usages. Fish processing plants
,Agricultural farms, waste water of industrial zones and hospitals
waste water which they are generate by human activity produce a
considerable volume of effluent and when they are released in to the
stream they can effect on the water quality and down stream aquatic
systems. This study was conducted to evaluate the effects of outflow
effluent from different human activity and point and non point
pollution sources on the water quality and health of the Beshar
river next to Yasuj. Yasuj is the biggest and most important city in
the Kohkiloye and Boyerahmad province . The Beshar River is one
of the most important aquatic ecosystems in the upstream of the
Karun watershed in south of Iran which is affected by point and non
point pollutant sources . This study was done in order to evaluate the
effects of human activities on the water quality and health of the
Beshar river. This river is approximately 190 km in length and
situated at the geographical positions of 51° 20' to 51° 48' E and 30°
18' to 30° 52' N it is one of the most important aquatic ecosystems of
Kohkiloye and Boyerahmad province in south-west Iran. In this
research project, five study stations were selected to examine water
pollution in the Beshar River systems. Human activity is now one of
the most important factors affecting on hydrology and water quality
of the Beshar river. Humans use large amounts of resources to sustain
various standards of living, although measures of sustainability are
highly variable depending on how sustainability is defined. The
Beshar river ecosystems are particularly sensitive and vulnerable to
human activities. The water samples were analyzed, then some
important water quality parameters such as pH, dissolve oxygen
(DO), Biochemical Oxygen Demand (BOD5), Chemical Oxygen
Demand (COD), Total Suspended Solids (TDS),Turbidity,
Temperature, Nitrates (NO3) and Phosphates (PO4) were estimated
at the two stations. The results show a downward trend in the water
quality at the down stream of the city. The amounts of
BOD5,COD,TSS,T,Turbidity, NO3 and PO4 in the down stream
stations were considerably more than the station 1. By contrast the
amounts of DO in the down stream stations were less than to the
station 1. However when effluent discharge consequence of human
activities are released into the Beshar river near the city, the quality
of river are decreases and the environmental problems of the river
during the next years are predicted to rise.
Abstract: A typical definition of the Computer Aided Diagnosis
(CAD), found in literature, can be: A diagnosis made by a radiologist
using the output of a computerized scheme for automated image
analysis as a diagnostic aid. Often it is possible to find the expression
Computer Aided Detection (CAD or CADe): this definition
emphasizes the intent of CAD to support rather than substitute the
human observer in the analysis of radiographic images. In this article
we will illustrate the application of CAD systems and the aim of
these definitions.
Commercially available CAD systems use computerized
algorithms for identifying suspicious regions of interest. In this paper
are described the general CAD systems as an expert system
constituted of the following components: segmentation / detection,
feature extraction, and classification / decision making.
As example, in this work is shown the realization of a Computer-
Aided Detection system that is able to assist the radiologist in
identifying types of mammary tumor lesions. Furthermore this
prototype of station uses a GRID configuration to work on a large
distributed database of digitized mammographic images.
Abstract: Web usage mining is an interesting application of data
mining which provides insight into customer behaviour on the Internet. An important technique to discover user access and navigation trails is based on sequential patterns mining. One of the
key challenges for web access patterns mining is tackling the problem
of mining richly structured patterns. This paper proposes a novel
model called Web Access Patterns Graph (WAP-Graph) to represent all of the access patterns from web mining graphically. WAP-Graph
also motivates the search for new structural relation patterns, i.e. Concurrent Access Patterns (CAP), to identify and predict more
complex web page requests. Corresponding CAP mining and modelling methods are proposed and shown to be effective in the
search for and representation of concurrency between access patterns
on the web. From experiments conducted on large-scale synthetic
sequence data as well as real web access data, it is demonstrated that
CAP mining provides a powerful method for structural knowledge discovery, which can be visualised through the CAP-Graph model.
Abstract: Pummelo is known to be the largest of all citrus fruits, with expected ratio of 2:1 (w/v) of producing juice, is an attractive opportunity for Malaysia to expand pummelo-s influence and marketability over the international market of juices. The purpose of this study is to identify and quantify the phenolic compounds in two Malaysian varieties of pummelo fruit juice: Ledang (PO55) and Tambun (PO52). Identifications of polyphenols composition were done using High Performance Liquid Chromatography Diode Array Detection (HPLC-DAD). The phenolic compounds that were found in both varieties were hydroxycinnamic acids and flavonones. This study proved that Tambun variety has the highest antioxidant and phenolic compounds in comparison to Ledang variety. However, considerations have to be made to suit consumer-s taste bud and the amount of enzyme needed to clarify the juice for its marketability.
Abstract: Mycotoxin (aflatoxins) contamination of peanuts is a
great concern for human health. A total of 72 samples of unripe,
roasted, and salty peanuts were collected randomly from Pothohar
plateau of Pakistan for the assessment of aflatoxin. Samples were
dried, ground and extracted by acetonitrile (84%). The filtered
extracts were cleaned up by MycoSep-226 and analyzed by high
performance liquid chromatography with flourescence detector.
Quantification limit of Aflatoxin was 1 μg/kg and 70% Recovery was
observed in spiked samples in the range 1–10 μg/kg. The screening
of mycotoxins indicated that aflatoxins were present in most of the
samples being detected in 82%, in concentrations from 14.25 μg/kg
to 98.80 μg/kg. Optimal conditions for mycotoxin production and
fungal growth are frequently found in the crop fields as well as in
store houses. Human exposure of such toxin can be controlled by
pointed out such awareness and implemented the regulations.
Abstract: The use of new technologies such internet (e-mail, chat
rooms) and cell phones has steeply increased in recent years.
Especially among children and young people, use of technological
tools and equipments is widespread. Although many teachers and
administrators now recognize the problem of school bullying, few are
aware that students are being harassed through electronic
communication. Referred to as electronic bullying, cyber bullying, or
online social cruelty, this phenomenon includes bullying through email,
instant messaging, in a chat room, on a website, or through
digital messages or images sent to a cell phone. Cyber bullying is
defined as causing deliberate/intentional harm to others using internet
or other digital technologies. It has a quantitative research design nd
uses relational survey as its method. The participants consisted of
300 secondary school students in the city of Konya, Turkey. 195
(64.8%) participants were female and 105 (35.2%) were male. 39
(13%) students were at grade 1, 187 (62.1%) were at grade 2 and 74
(24.6%) were at grade 3. The “Cyber Bullying Question List"
developed by Ar─▒cak (2009) was given to students. Following
questions about demographics, a functional definition of cyber
bullying was provided. In order to specify students- human values,
“Human Values Scale (HVS)" developed by Dilmaç (2007) for
secondary school students was administered. The scale consists of 42
items in six dimensions. Data analysis was conducted by the primary
investigator of the study using SPSS 14.00 statistical analysis
software. Descriptive statistics were calculated for the analysis of
students- cyber bullying behaviour and simple regression analysis was
conducted in order to test whether each value in the scale could
explain cyber bullying behaviour.
Abstract: In this work, the primary compressive strength
components of human femur trabecular bone are qualitatively
assessed using image processing and wavelet analysis. The Primary
Compressive (PC) component in planar radiographic femur trabecular
images (N=50) is delineated by semi-automatic image processing
procedure. Auto threshold binarization algorithm is employed to
recognize the presence of mineralization in the digitized images. The
qualitative parameters such as apparent mineralization and total area
associated with the PC region are derived for normal and abnormal
images.The two-dimensional discrete wavelet transforms are utilized
to obtain appropriate features that quantify texture changes in medical
images .The normal and abnormal samples of the human femur are
comprehensively analyzed using Harr wavelet.The six statistical
parameters such as mean, median, mode, standard deviation, mean
absolute deviation and median absolute deviation are derived at level
4 decomposition for both approximation and horizontal wavelet
coefficients. The correlation coefficient of various wavelet derived
parameters with normal and abnormal for both approximated and
horizontal coefficients are estimated. It is seen that in almost all cases
the abnormal show higher degree of correlation than normals. Further
the parameters derived from approximation coefficient show more
correlation than those derived from the horizontal coefficients. The
parameters mean and median computed at the output of level 4 Harr
wavelet channel was found to be a useful predictor to delineate the
normal and the abnormal groups.