Abstract: In vitro gastro-duodenal digestion model was used to investigate the changes of emulsions under digestion conditions. Oil in water emulsions stabilized by whey proteins (2%) and stabilized by whey proteins (2%) with addition of carboxymethyl cellulose (0.75%) as gelling agent of continuous phase were prepared at pH7. Both emulsions were destabilized under gastric conditions; however the protective role of carboxymethyl cellulose was indicated by recording delay of fat digestibility of this emulsion. In the presence of carboxymethyl cellulose whey proteins on the interfacial surface of droplets were more resistant to gastric degradation causing limited hydrolysis of fat due to the poor acceptability of lipids for the enzymes. Studies of emulsions using in vivo model supported results from in vitro studies. Lower content of triglycerides in blood serum and higher amount of fecal fat of rats were determined when rats were fed by diet containing emulsion made with whey proteins and carboxymethyl cellulose.
Abstract: Mutations of the telomeric copy of the survival motor neuron 1 (SMN1) gene cause spinal muscular atrophy. A deletion of the Eef1a2 gene leads to lower motor neuron degeneration in wasted mice. Indirect evidences have been shown that the eEF1A protein family may interact with SMN, and our previous study showed that abnormalities of neuromuscular junctions in wasted mice were similar to those of Smn mutant mice. To determine potential colocalization between SMN and tissue-specific translation elongation factor 1A2 (eEF1A2), an immunochemical analysis of HeLa cells transfected with the plasmid pcDNA3.1(+)C-hEEF1A2- myc and a new quantitative test of colocalization by intensity correlation analysis (ICA) was used to explore the association of SMN and eEF1A2. Here the results showed that eEF1A2 redistributed from the cytoplasm to the nucleus in response to serum and epidermal growth factor. In the cytoplasm, compelling evidence showed that staining for myc-tagged eEF1A2 varied in synchrony with that for SMN, consistent with the formation of a SMN-eEF1A2 complex in the cytoplasm of HeLa cells. These findings suggest that eEF1A2 may colocalize with SMN in the cytoplasm and may be a component of the SMN complex. However, the limitation of the ICA method is an inability to resolve colocalization in components of small organelles such as the nucleus.
Abstract: Promoting critical thinking (CT) in an educational
setting has been appraised in order to enhance learning and
intellectual skills. In this study, a pedagogical course in a vocational
teacher education program in Turkey was designed by integrating CT
skill-based strategies/activities into the course content and CT skills
were means leading to intended course objectives. The purpose of the
study was to evaluate the importance of the course objectives, the
attainment of the objectives, and the effectiveness of teachinglearning
strategies/activities from prospective teachers- points of
view. The results revealed that although the students mostly
considered the course objectives important, they did not feel
competent in the attainment of all objectives especially in those
related to the main topic of Learning and those requiring higher order
thinking skills. On the other hand, the students considered the course
activities effective for learning and for the development of thinking
skills, especially, in interpreting, comparing, questioning,
contrasting, and forming relationships.
Abstract: Relevant agricultural information disseminator
(extension agent) ratio of 1:3500 farm families which become a
menace to agricultural production capacity in developing countries
necessitate this study. Out of 4 zones in the state, 24 extension agents
in each zone, 4 extension agents using cell phones and 120 farmers
using cell phone and 120 other farmers not using cell phone were
purposively selected to give 240 farmers that participated in the
research. Data were collected using interview guide and analysized
using frequency, percentage and t-test.. Frequency of contact with
agricultural information centers revealed that cell phone user farmers
had greater means score of X 41.43 contact as against the low mean
X19.32 contact recorded by farmers receiving agricultural
information from extension agents not using cell phone and their
production was statistically significant at P < 0.05. Usage of cell
phone increase extension agent contact and increase farmers-
production capacity.
Abstract: In this paper we are interested in Moufang-Klingenberg
planesM(A) defined over a local alternative ring A of dual numbers.
We show that some collineations of M(A) preserve cross-ratio.
Abstract: As the fossil fuels kept on depleting, intense research in developing hydrogen (H2) as the alternative fuel has been done to cater our tremendous demand for fuel. The potential of H2 as the ultimate clean fuel differs with the fossil fuel that releases significant amounts of carbon dioxide (CO2) into the surrounding and leads to the global warming. The experimental work was carried out to study the production of H2 from palm kernel shell steam gasification at different variables such as heating rate, steam to biomass ratio and adsorbent to biomass ratio. Maximum H2 composition which is 61% (volume basis) was obtained at heating rate of 100oCmin-1, steam/biomass of 2:1 ratio, and adsorbent/biomass of 1:1 ratio. The commercial adsorbent had been modified by utilizing the alcoholwater mixture. Characteristics of both adsorbents were investigated and it is concluded that flowability and floodability of modified CaO is significantly improved.
Abstract: A study was carried out to determine the effect of water quality on flotation performance. The experimental test work comprised of batch flotation tests using Denver lab cell for a period of 10 minutes. Nine different test runs were carried out in triplicates to ensure reproducibility using different water types from different thickener overflows, return and sewage effluent water (process water) and portable water. The water sources differed in pH, total dissolved solids, total suspended solids and conductivity. Process water was found to reduce the concentrate recovery and mass pull, while portable water increased the concentrate recovery and mass pull. Portable water reduced the concentrate grade while process water increased the concentrate grade. It is proposed that a combination of process water and portable water supply be used in flotation circuits to balance the different effects that the different water types have on the flotation efficiency.
Abstract: Structural representation and technology mapping of
a Boolean function is an important problem in the design of nonregenerative
digital logic circuits (also called combinational logic
circuits). Library aware function manipulation offers a solution to
this problem. Compact multi-level representation of binary networks,
based on simple circuit structures, such as AND-Inverter Graphs
(AIG) [1] [5], NAND Graphs, OR-Inverter Graphs (OIG), AND-OR
Graphs (AOG), AND-OR-Inverter Graphs (AOIG), AND-XORInverter
Graphs, Reduced Boolean Circuits [8] does exist in
literature. In this work, we discuss a novel and efficient graph
realization for combinational logic circuits, represented using a
NAND-NOR-Inverter Graph (NNIG), which is composed of only
two-input NAND (NAND2), NOR (NOR2) and inverter (INV) cells.
The networks are constructed on the basis of irredundant disjunctive
and conjunctive normal forms, after factoring, comprising terms with
minimum support. Construction of a NNIG for a non-regenerative
function in normal form would be straightforward, whereas for the
complementary phase, it would be developed by considering a virtual
instance of the function. However, the choice of best NNIG for a
given function would be based upon literal count, cell count and
DAG node count of the implementation at the technology
independent stage. In case of a tie, the final decision would be made
after extracting the physical design parameters.
We have considered AIG representation for reduced disjunctive
normal form and the best of OIG/AOG/AOIG for the minimized
conjunctive normal forms. This is necessitated due to the nature of
certain functions, such as Achilles- heel functions. NNIGs are found
to exhibit 3.97% lesser node count compared to AIGs and
OIG/AOG/AOIGs; consume 23.74% and 10.79% lesser library cells
than AIGs and OIG/AOG/AOIGs for the various samples considered.
We compare the power efficiency and delay improvement achieved
by optimal NNIGs over minimal AIGs and OIG/AOG/AOIGs for
various case studies. In comparison with functionally equivalent,
irredundant and compact AIGs, NNIGs report mean savings in power
and delay of 43.71% and 25.85% respectively, after technology
mapping with a 0.35 micron TSMC CMOS process. For a
comparison with OIG/AOG/AOIGs, NNIGs demonstrate average
savings in power and delay by 47.51% and 24.83%. With respect to
device count needed for implementation with static CMOS logic
style, NNIGs utilize 37.85% and 33.95% lesser transistors than their
AIG and OIG/AOG/AOIG counterparts.
Abstract: Transpedicular screw fixation in spinal fractures,
degenerative changes, or deformities is a well-established procedure.
However, important rate of fixation failure due to screw bending,
loosening, or pullout are still reported particularly in weak bone stock
in osteoporosis. To overcome the problem, mechanism of failure has
to be fully investigated in vitro. Post-mortem human subjects are less
accessible and animal cadavers comprise limitations due to different
geometry and mechanical properties. Therefore, the development of a
synthetic model mimicking the realistic human vertebra is highly
demanded. A bone surrogate, composed of Polyurethane (PU) foam
analogous to cancellous bone porous structure, was tested for 3
different densities in this study. The mechanical properties were
investigated under uniaxial compression test by minimizing the end
artifacts on specimens. The results indicated that PU foam of 0.32
g.cm-3 density has comparable mechanical properties to human
cancellous bone in terms of young-s modulus and yield strength.
Therefore, the obtained information can be considered as primary
step for developing a realistic cancellous bone of human vertebral
body. Further evaluations are also recommended for other density
groups.
Abstract: In this paper, we have proposed a novel FinFET with
extended body under the poly gate, which is called EB-FinFET, and
its characteristic is demonstrated by using three-dimensional (3-D)
numerical simulation. We have analyzed and compared it with
conventional FinFET. The extended body height dependence on the
drain induced barrier lowering (DIBL) and subthreshold swing (S.S)
have been also investigated. According to the 3-D numerical
simulation, the proposed structure has a firm structure, an acceptable
short channel effect (SCE), a reduced series resistance, an increased
on state drain current (I
on) and a large normalized I
DS. Furthermore,
the structure can also improve corner effect and reduce self-heating
effect due to the extended body. Our results show that the EBFinFET
is excellent for nanoscale device.
Abstract: The background estimation approach using a small
window median filter is presented on the bases of analyzing IR point
target, noise and clutter model. After simplifying the two-dimensional
filter, a simple method of adopting one-dimensional median filter is
illustrated to make estimations of background according to the
characteristics of IR scanning system. The adaptive threshold is used
to segment canceled image in the background. Experimental results
show that the algorithm achieved good performance and satisfy the
requirement of big size image-s real-time processing.
Abstract: Hydrogen is considered to be the most promising
candidate as a future energy carrier. One of the most used
technologies for the electrolytic hydrogen production is alkaline
water electrolysis. However, due to the high energy requirements, the
cost of hydrogen produced in such a way is high. In continuous
search to improve this process using advanced electrocatalytic
materials for the hydrogen evolution reaction (HER), Ni type Raney
and macro-porous Ni-Co electrodes were prepared on AISI 304
stainless steel substrates by electrodeposition. The developed
electrodes were characterized by SEM and confocal laser scanning
microscopy. HER on these electrodes was evaluated in 30 wt.% KOH
solution by means of hydrogen discharge curves and galvanostatic
tests. Results show that the developed electrodes present a most
efficient behaviour for HER when comparing with the smooth Ni
cathode. It has been reported a reduction in the energy consumption
of the electrolysis cell of about 25% by using the developed coatings
as cathodes.
Abstract: This paper presents an equivalent circuit model based on piecewise linear parallel branches (PLPB) to study solar cell modules which are partially shaded. The PLPB model can easily be used in circuit simulation software such as the ElectroMagnetic Transients Program (EMTP). This PLPB model allows the user to simulate several different configurations of solar cells, the influence of partial shadowing on a single or multiple cells, the influence of the number of solar cells protected by a bypass diode and the effect of the cell connection configuration on partial shadowing.
Abstract: The inhibition effect of brazilin to human bladder
tumor cell line T24 in vitro and in vivo was studied. The results of the
in vitro experiments showed that brazilin has strong inhibition activity
on the target cells. The inhibition ratio of 100 μg/mL brazilin and 100
μg/mL mitomycin to the target cells was 90.90 % and 63.24 %
respectively, which showed that brazilin has higher inhibition activity
than mitomycin under the same concentration. Brazilin could induce
cell apoptosis in T24 cells. Significant antitumor activity of brazilin
was also showed in the animals experiments. The life extention rate of
200 mg/mL, 300 mg/kg, and 400 mg/kg brazilin intraperitoneally
injected into Balb/c-nu-nu nude mice that with human bladder cancer
were 51.50 %, 56.90 %, and 58.42 %（P
Abstract: This study describes a micro device integrated with
multi-chamber for polymerase chain reaction (PCR) with different
annealing temperatures. The device consists of the reaction
polydimethylsiloxane (PDMS) chip, a cover glass chip, and is
equipped with cartridge heaters, fans, and thermocouples for
temperature control. In this prototype, commercial software is utilized
to determine the geometric and operational parameters those are
responsible for creating the denaturation, annealing, and extension
temperatures within the chip. Two cartridge heaters are placed at two
sides of the chip and maintained at two different temperatures to
achieve a thermal gradient on the chip during the annealing step. The
temperatures on the chip surface are measured via an infrared imager.
Some thermocouples inserted into the reaction chambers are used to
obtain the transient temperature profiles of the reaction chambers
during several thermal cycles. The experimental temperatures
compared to the simulated results show a similar trend. This work
should be interesting to persons involved in the high-temperature
based reactions and genomics or cell analysis.
Abstract: Increasing use of cell phone as a medium of human interaction is playing a vital role in solving riddles of crime as well. A young girl went missing from her home late in the evening in the month of August, 2008 when her enraged relatives and villagers physically assaulted and chased her fiancée who often frequented her home. Two years later, her mother lodged a complaint against the relatives and the villagers alleging that after abduction her daughter was either sold or killed as she had failed to trace her. On investigation, a rusted cell phone with partial visible IMEI number, clothes, bangles, human skeleton etc. recovered from abandoned well in the month of May, 2011 were examined in the lab. All hopes pinned on identity of cell phone, for only linking evidence to fix the scene of occurrence supported by call detail record (CDR) and to dispel doubts about mode of sudden disappearance or death as DNA technology did not help in establishing identity of the deceased. The conventional scientific methods were used without success and international mobile equipment identification number of the cell phone could be generated by using statistical analysis followed by online verification.
Abstract: Environmental micro-organisms include a large number of taxa and some species that are generally considered nonpathogenic, but can represent a risk in certain conditions, especially for elderly people and immunocompromised individuals. Chemotaxonomic identification techniques are powerful tools for environmental micro-organisms, and cellular fatty acid methyl esters (FAME) content is a powerful fingerprinting identification technique. A system based on an unsupervised artificial neural network (ANN) was set up using the fatty acid profiles of standard bacterial strains, obtained by gas-chromatography, used as learning data. We analysed 45 certified strains belonging to Acinetobacter, Aeromonas, Alcaligenes, Aquaspirillum, Arthrobacter, Bacillus, Brevundimonas, Enterobacter, Flavobacterium, Micrococcus, Pseudomonas, Serratia, Shewanella and Vibrio genera. A set of 79 bacteria isolated from a drinking water line (AMGA, the major water supply system in Genoa) were used as an example for identification compared to standard MIDI method. The resulting ANN output map was found to be a very powerful tool to identify these fresh isolates.
Abstract: Porcelain specimens were fired at 6C/min to 1250C (dwell time 0.5-3h) and cooled at 6C/min to room temperature. Additionally, three different slower firing/cooling cycles were tried. Sintering profile and effects on MOR, crystalline phase content and morphology were investigated using dilatometry, 4-point bending strength, XRD and FEG-SEM respectively. Industrial-sized specimens prepared using the promising cycle were tested basing on the ANSI standards. Increasing dwell time from 1h to 3h at peak temperature of 1250C resulted in neither a significant effect on the quartz and mullite content nor MOR. Reducing the firing/cooling rate to below 6C/min, for peak temperature of 1250C (dwell time of 1h) does not result in improvement of strength of porcelain. The industrial sized specimen exhibited flashover voltages of 20.3kV (dry) and 9.3kV (wet) respectively, transverse strength of 12.5kN and bulk density of 2.27g/cm3, which are satisfactory. There was however dye penetration during porosity test. KeywordsDwell time, Microstructure, Porcelain, Strength.
Abstract: The source voltage of high-power fuel cell shows strong load dependence at comparatively low voltage levels. In order to provide the voltage of 750V on the DC-link for feeding electrical energy into the mains via a three phase inverter a step-up converter with a large step-up ratio is required. The output voltage of this DC/DC-converter must be stabile during variations of the load current and the voltage of the fuel cell. This paper presents the methods and results of the calculation of the efficiency and the expense for the realization for the circuits of the DC/DC-converter that meet these requirements.
Abstract: This study evaluates the performance of horizontal
subsurface flow constructed wetland (HSSF-CW) for the removal of
chlorinated resin and fatty acids (RFAs) from pulp and paper mill
wastewater. The dimensions of the treatment system were 3.5 m x 1.5
m x 0.28 m with surface area of 5.25 m2, filled with fine sand and
gravel. The cell was planted with an ornamental plant species Canna
indica. The removal efficiency of chlorinated RFAs was in the range
of 92-96% at the hydraulic retention time (HRT) of 5.9 days. Plant
biomass and soil (sand and gravel) were analyzed for chlorinated
RFAs content. No chlorinated RFAs were detected in plant biomass
but detected in soil samples. Mass balance studies of chlorinated
RFAs in HSSF-CW were also carried out.