Abstract: Oxidative stress makes up common incidents in
eukaryotic metabolism. The presence of diverse components
disturbing the equilibrium during oxygen metabolism increases
oxidative damage unspecifically in living cells. Body´s own
ubiquinone (Q10) seems to be a promising drug in defending the
heightened appearance of reactive oxygen species (ROS). Though, its
lipophilic properties require a new strategy in drug formulation to
overcome their low bioavailability. Consequently, the manufacture of
heterogeneous nanodispersions is in focus for medical applications.
The composition of conventional nanodispersions is made up of a
drug-consisting core and a surfactive agent, also named as surfactant.
Long-termed encapsulation of the surfactive components into tissues
might be the consequence of the use during medical therapeutics. The
potential of provoking side-effects is given by their nonbiodegradable
properties. Further improvements during fabrication
process use the incorporation of biodegradable components such as
modified γ-polyglutamic acid which decreases the potential of
prospective side-effects.
Abstract: This paper presents the control performance of a high-precision positioning device using the hybrid actuator composed of a piezoelectric (PZT) actuator and a voice-coil motor (VCM). The combined piezo-VCM actuator features two main characteristics: a large operation range due to long stroke of the VCM, and high precision and heavy load positioning ability due to PZT impact force. A one-degree-of-freedom (DOF) experimental setup was configured to examine the fundamental characteristics, and the control performance was effectively demonstrated by using a switching controller. In rough positioning state, an integral variable structure controller (IVSC) was used for the VCM to conduct long range of operation; in precision positioning state, an impact force controller (IFC) for the PZT actuator coupled with presliding states of the sliding table was used to obtain high-precision position control and achieve both forward and backward actuations. The experimental results showed that the sliding table having a mass of 881g and with a preload of 10 N was successfully positioned within the positioning accuracy of 10 nm in both forward and backward position controls.
Abstract: This study has investigated the antidiabetic and
antioxidant potential of Pseudovaria macrophylla bark extract on
streptozotocin–nicotinamide induced type 2 diabetic rats. LCMSQTOF
and NMR experiments were done to determine the chemical
composition in the methanolic bark extract. For in vivo experiments,
the STZ (60 mg/kg/b.w, 15 min after 120 mg/kg/1 nicotinamide, i.p.)
induced diabetic rats were treated with methanolic extract of
Pseuduvaria macrophylla (200 and 400 mg/kg·bw) and
glibenclamide (2.5 mg/kg) as positive control respectively.
Biochemical parameters were assayed in the blood samples of all
groups of rats. The pro-inflammatory cytokines, antioxidant status
and plasma transforming growth factor βeta-1 (TGF-β1) were
evaluated. The histological study of the pancreas was examined and
its expression level of insulin was observed by
immunohistochemistry. In addition, the expression of glucose
transporters (GLUT 1, 2 and 4) were assessed in pancreas tissue by
western blot analysis. The outcomes of the study displayed that the
bark methanol extract of Pseuduvaria macrophylla has potentially
normalized the elevated blood glucose levels and improved serum
insulin and C-peptide levels with significant increase in the
antioxidant enzyme, reduced glutathione (GSH) and decrease in the
level of lipid peroxidation (LPO). Additionally, the extract has
markedly decreased the levels of serum pro-inflammatory cytokines
and transforming growth factor beta-1 (TGF-β1). Histopathology
analysis demonstrated that Pseuduvaria macrophylla has the
potential to protect the pancreas of diabetic rats against peroxidation
damage by downregulating oxidative stress and elevated
hyperglycaemia. Furthermore, the expression of insulin protein,
GLUT-1, GLUT-2 and GLUT-4 in pancreatic cells was enhanced.
The findings of this study support the anti-diabetic claims of
Pseudovaria macrophylla bark.
Abstract: Background: Tissue Doppler Echocardiography
(TDE) assesses diastolic function more accurately than routine pulse
Doppler echo. Assessment of the effects of dynamic and static
exercises on the heart by using TDE can provides new information
about the athlete-s heart syndrome. Methods: This study was
conducted on 20 elite wrestlers, 14 endurance runners at national
level and 21 non-athletes as the control group. Participants underwent
two-dimensional echocardiography, standard Doppler and TDE.
Results: Wrestlers had the highest left ventricular mass index, enddiastolic
inter-ventricular septum thickness and left ventricular
Posterior wall thickness. Runners had the highest Left ventricular
end-diastolic volume, LV ejection fraction, stroke volume and
cardiac output. In TDE, the early diastolic velocity of mitral annulus
to the late diastolic velocity ratio in athletic groups was greater than
the controls with no significant difference. Conclusion: In spite of
cardiac morphological changes in athletes, TDE shows that cardiac
diastolic function won-t be adversely affected.
Abstract: An adaptive neural network controller for
autonomous underwater vehicles (AUVs) is presented in this paper.
The AUV model is highly nonlinear because of many factors, such as
hydrodynamic drag, damping, and lift forces, Coriolis and centripetal
forces, gravity and buoyancy forces, as well as forces from thruster.
In this regards, a nonlinear neural network is used to approximate the
nonlinear uncertainties of AUV dynamics, thus overcoming some
limitations of conventional controllers and ensure good performance.
The uniform ultimate boundedness of AUV tracking errors and the
stability of the proposed control system are guaranteed based on
Lyapunov theory. Numerical simulation studies for motion control of
an AUV are performed to demonstrate the effectiveness of the
proposed controller.
Abstract: Optimizing equipment selection in heavy earthwork
operations is a critical key in the success of any construction project.
The objective of this research incentive was geared towards
developing a computer model to assist contractors and construction
managers in estimating the cost of heavy earthwork operations.
Economical operation analysis was conducted for an equipment fleet
taking into consideration the owning and operating costs involved in
earthwork operations. The model is being developed in a Microsoft
environment and is capable of being integrated with other estimating
and optimization models. In this study, Caterpillar® Performance
Handbook [5] was the main resource used to obtain specifications of
selected equipment. The implementation of the model shall give
optimum selection of equipment fleet not only based on cost
effectiveness but also in terms of versatility. To validate the model, a
case study of an actual dam construction project was selected to
quantify its degree of accuracy.
Abstract: IEEE 802.11e is the enhanced version of the IEEE
802.11 MAC dedicated to provide Quality of Service of wireless
network. It supports QoS by the service differentiation and
prioritization mechanism. Data traffic receives different priority
based on QoS requirements. Fundamentally, applications are divided
into four Access Categories (AC). Each AC has its own buffer queue
and behaves as an independent backoff entity. Every frame with a
specific priority of data traffic is assigned to one of these access
categories. IEEE 802.11e EDCA (Enhanced Distributed Channel
Access) is designed to enhance the IEEE 802.11 DCF (Distributed
Coordination Function) mechanisms by providing a distributed
access method that can support service differentiation among
different classes of traffic. Performance of IEEE 802.11e MAC layer
with different ACs is evaluated to understand the actual benefits
deriving from the MAC enhancements.
Abstract: Most often the contaminants are not taken seriously into consideration, and this behavior comes out directly from the lack of monitoring and professional reporting about pollution in the printing facilities in Serbia. The goal of planned and systematic ozone measurements in ambient air of the screen printing facilities in Novi Sad is to examine of its impact on the employees health, and to track trends in concentration. In this study, ozone concentrations were determined by using discontinuous and continuous method during the automatic and manual screen printing process. Obtained results indicates that the average concentrations of ozone measured during the automatic process were almost 3 to 28 times higher for discontinuous and 10 times higher for continuous method (1.028 ppm) compared to the values prescribed by OSHA. In the manual process, average concentrations of ozone were within prescribed values for discontinuous and almost 3 times higher for continuous method (0.299 ppm).
Abstract: In this paper, we consider a multi user multiple input
multiple output (MU-MIMO) based cooperative reporting system for
cognitive radio network. In the reporting network, the secondary
users forward the primary user data to the common fusion center
(FC). The FC is equipped with linear equalizers and an energy
detector to make the decision about the spectrum. The primary user
data are considered to be a digital video broadcasting - terrestrial
(DVB-T) signal. The sensing channel and the reporting channel are
assumed to be an additive white Gaussian noise and an independent
identically distributed Raleigh fading respectively. We analyzed the
detection probability of MU-MIMO system with linear equalizers and
arrived at the closed form expression for average detection
probability. Also the system performance is investigated under
various MIMO scenarios through Monte Carlo simulations.
Abstract: Frequent patterns are patterns such as sets of features or items that appear in data frequently. Finding such frequent patterns has become an important data mining task because it reveals associations, correlations, and many other interesting relationships hidden in a dataset. Most of the proposed frequent pattern mining algorithms have been implemented with imperative programming languages such as C, Cµ, Java. The imperative paradigm is significantly inefficient when itemset is large and the frequent pattern is long. We suggest a high-level declarative style of programming using a functional language. Our supposition is that the problem of frequent pattern discovery can be efficiently and concisely implemented via a functional paradigm since pattern matching is a fundamental feature supported by most functional languages. Our frequent pattern mining implementation using the Haskell language confirms our hypothesis about conciseness of the program. The performance studies on speed and memory usage support our intuition on efficiency of functional language.
Abstract: New nondestructive technique, namely an inverse technique based on vibration tests, to characterize nonlinear mechanical properties of adhesive layers in sandwich composites is developed. An adhesive layer is described as a viscoelastic isotropic material with storage and loss moduli which are both frequency dependent values in wide frequency range. An optimization based on the planning of experiments and response surface technique to minimize the error functional is applied to decrease considerably the computational expenses. The developed identification technique has been tested on aluminum panels and successfully applied to characterize viscoelastic material properties of 3M damping polymer ISD-112 used as a core material in sandwich panels.
Abstract: An experiment was conducted to determine the effect
of the rearing system on growth performance, carcass yield,
hematological parameters, and feather pecking damage of Thai
indigenous chickens. Three hundred and sixty 1-d-old chicks were
randomly assigned to 2 treatments: indoor treatment and outdoor
access treatment. In the indoor treatment, the chickens were housed
in floor pens (5 birds/m2). In the outdoor access treatment, the
chickens were housed in a similar indoor house; in addition, they also
had an outdoor grass paddock (1 bird/m2). All birds were provided
with same diet and were raised for 16 wk of age. The results showed
that growth performance and carcass yield were not different among
treatment (P>0.05). Outdoor access had no effect on hematological
parameters (P>0.05). However, the feather pecking damage of the
chickens in the outdoor access treatment was lower than that of the
chickens in the indoor treatment (P
Abstract: The paper presents the results of research on trends in shaping of multifamily buildings in Poland on the example of Wrocław, after Polish accession to the European Union. The study is conducted within the research project: “Trends in creating of multifamily housing development since 2004, on the Wrocław study case" supported by Polish Ministry of Science and Higher Education and will be completed in November 2011. The research involves multifamily buildings completed in the last decade, in term of fundamental urbanization factors such as: building-s coefficient area, useable area, green area (biologically active surface), intensity of building development, amount of dwellings, dwelling area, amount of parking places, numbers of floors, etc. The analysis of these indicators was conducted based on the date obtained in the study of approximately one hundred new housing units, completed in Wroclaw. The analysis attempts to formulate the main trends in creating of housing policy in Poland during the last 10 years in reference to local urban policy.
Abstract: We analyze the effectivity of different pseudo noise (PN) and orthogonal sequences for encrypting speech signals in terms of perceptual intelligence. Speech signal can be viewed as sequence of correlated samples and each sample as sequence of bits. The residual intelligibility of the speech signal can be reduced by removing the correlation among the speech samples. PN sequences have random like properties that help in reducing the correlation among speech samples. The mean square aperiodic auto-correlation (MSAAC) and the mean square aperiodic cross-correlation (MSACC) measures are used to test the randomness of the PN sequences. Results of the investigation show the effectivity of large Kasami sequences for this purpose among many PN sequences.
Abstract: Explosion occurs due to sudden release of energy.
Common examples of explosion include chemical, atomic, heat, and
pressure tank (due to ignition) explosions. Petroleum, gas, and
petrochemical industries operations are threatened by natural risks
and processes. Fires and explosions are the greatest process risks
which cause financial damages.
This study aims at designing a single-floor structure for the control
room of a petroleum refinery to be resistant against gas explosion
loads, and the information related to the structure specifications have
been provided regarding the fact that the structure is made on the
ground's surface. In this research, the lateral stiffness of single pile is
calculated by SPPLN.FOR computer program, and its value for
13624 KN/m single pile has been assessed. The analysis used due to
the loading conditions, is dynamic nonlinear analysis with direct
integration method.
Abstract: The objective of the present study was to examine the
dose-response relationships between antioxidant parameters and liver
contaminant levels of Kazakhstan light crude oil (KLCO) in albino
rats. The animals were repeatedly exposed, by intraperitoneal
injection, to low dosages (0.5–1.5 ml/kg) of KLCO. Rats exposed to
these doses levels did not show any apparent symptoms of
intoxication. Serum aminotransferases increased significantly
(p
Abstract: Polyurethanes (PURs) are very versatile polymeric
materials with a wide range of physical and chemical properties.
PURs have desirable properties such as high abrasion resistance, tear
strength, shock absorption, flexibility and elasticity. Although they
have relatively poor thermal stability, this can be improved by using
treated clay. Polyurethane/clay nanocomposites have been
synthesized from renewable sources. A polyol for the production of
polyurethane by reaction with an isocyanate was obtained by the
synthesis of palm oil-based oleic acid with glycerol. Dodecylbenzene
sulfonic acid (DBSA) was used as catalyst and emulsifier. The
unmodified clay (kunipia-F) was treated with cetyltrimethyl
ammonium bromide (CTAB-mont) and octadodecylamine (ODAmont).
The d-spacing in CTAB-mont and ODA-mont were 1.571 nm
and 1.798 nm respectively and larger than that of the pure-mont
(1.142 nm). The organoclay was completely intercalated in the
polyurethane, as confirmed by a wide angle x-ray diffraction
(WAXD) pattern.
The results showed that adding clay demonstrated better thermal
stability in comparison with the virgin polyurethane. Onset
degradation of pure PU is at 200oC, and is lower than that of the
CTAB-mont PU and ODA-mont PU which takes place at about
318oC and 330oC, respectively. The mechanical properties (including
the dynamic mechanical properties) of pure polyurethane (PU) and
PU/clay nanocomposites, were measured. The modified organoclay
had a remarkably beneficial effect on the strength and elongation at
break of the nanocomposites, which both increased with increasing
clay content with the increase of the tensile strength of more than
214% and 267% by the addition of only 5 wt% of the
montmorillonite CTAB-mont PU and ODA-mont PU, respectively.
Abstract: Ionic liquids are well known as green solvents, reaction media and catalysis. Here, three different sulfonic acid functional ionic liquids prepared in the laboratory are used as catalysts in alkylation of p-cresol with tert-butyl alcohol. The kinetics on each of the catalysts was compared and a kinetic model was developed based on the product distribution over these catalysts. The kinetic parameters were estimated using Marquadt's algorithm to minimize the error function. The Arrhenius plots show a curvature which is best interpreted by the extended Arrhenius equation.
Abstract: Genetic algorithms (GAs) have been widely used for
global optimization problems. The GA performance depends highly
on the choice of the search space for each parameter to be optimized.
Often, this choice is a problem-based experience. The search space
being a set of potential solutions may contain the global optimum
and/or other local optimums. A bad choice of this search space
results in poor solutions. In this paper, our approach consists in
extending the search space boundaries during the GA optimization,
only when it is required. This leads to more diversification of GA
population by new solutions that were not available with fixed search
space boundaries. So, these dynamic search spaces can improve the
GA optimization performances. The proposed approach is applied to
power system stabilizer optimization for multimachine power system
(16-generator and 68-bus). The obtained results are evaluated and
compared with those obtained by ordinary GAs. Eigenvalue analysis
and nonlinear system simulation results show the effectiveness of the
proposed approach to damp out the electromechanical oscillation and
enhance the global system stability.
Abstract: From the beginning of creation, human being has ever
fought against the ecosystem by changes has made in environment.
The most environmental changes on the nature have been done after
starting the concentrated life in the same region. Dams are one of the
most important buildings in water resources and transferring. These
buildings have been made from old times without access to
hydrological, hydraulically, hydro mechanical information. Dams
have positive and negative effects on environment. Constructing a
dam relatively causes equal ecological consequences. According to
different criteria, environmental effects of dams can lead short term
and long term damages. These effects may influence on the situation
and treatment of meteorology, biology, culture, ancient works, etc
and severely causes to change and complicate it. So considering
importance of positive effects of dam construction, it is necessary to
minimize negative environmental effects of dams to achieve a stable
development. In this article the considered effects and their solutions
in influencing on assessment of destructive environmental effects of
dams construction have been surveyed and presented.