Abstract: Most of the drugs used for pharmaceutical purposes
are poorly water-soluble drugs. About 40% of all newly discovered
drugs are lipophilic and the numbers of lipophilic drugs seem to
increase more and more. Drug delivery systems such as
nanoparticles, micelles or liposomes are applied to improve their
solubility and thus their bioavailability. Besides various techniques of
solubilization, oil-in-water emulsions are often used to incorporate
lipophilic drugs into the oil phase. To stabilize emulsions surface
active substances (surfactants) are generally used. An alternative
method to avoid the application of surfactants was of great interest.
One possibility is to develop O/W-emulsion without any addition of
surface active agents or the so called “surfactant-free emulsion or
SFE”. The aim of this study was to develop and characterize SFE as a
drug carrier by varying the production conditions. Lidocaine base
was used as a model drug. The injection method was developed.
Effects of ultrasound as well as of temperature on the properties of
the emulsion were studied. Particle sizes and release were
determined. The long-term stability up to 30 days was performed.
The results showed that the surfactant-free O/W emulsions with
pharmaceutical oil as drug carrier can be produced.
Abstract: In this paper, we investigate a blind channel estimation method for Multi-carrier CDMA systems that use a subspace decomposition technique. This technique exploits the orthogonality property between the noise subspace and the received user codes to obtain channel of each user. In the past we used Singular Value Decomposition (SVD) technique but SVD have most computational complexity so in this paper use a new algorithm called URV Decomposition, which serve as an intermediary between the QR decomposition and SVD, replaced in SVD technique to track the noise space of the received data. Because of the URV decomposition has almost the same estimation performance as the SVD, but has less computational complexity.
Abstract: Extraction of Fe(III) from aqueous solution using Trin-
butyl Phosphate (TBP) as carrier needs a highly acidic medium
(>6N) as it favours formation of chelating complex FeCl3.TBP.
Similarly, stripping of Iron(III) from loaded organic solvents requires
neutral pH or alkaline medium to dissociate the same complex. It is
observed that TBP co-extracts acids along with metal, which causes
reversal of driving force of extraction and iron(III) is re-extracted
back from the strip phase into the feed phase during Liquid Emulsion
Membrane (LEM) pertraction. Therefore, rate of extraction of
different mineral acids (HCl, HNO3, H2SO4) using TBP with and
without presence of metal Fe(III) was examined. It is revealed that in
presence of metal acid extraction is enhanced. Determination of mass
transfer coefficient of both acid and metal extraction was performed
by using Bulk Liquid Membrane (BLM). The average mass transfer
coefficient was obtained by fitting the derived model equation with
experimentally obtained data. The mass transfer coefficient of the
mineral acid extraction is in the order of kHNO3 = 3.3x10-6m/s > kHCl =
6.05x10-7m/s > kH2SO4 = 1.85x10-7m/s. The distribution equilibria of
the above mentioned acids between aqueous feed solution and a
solution of tri-n-butyl-phosphate (TBP) in organic solvents have been
investigated. The stoichiometry of acid extraction reveals the
formation of TBP.2HCl, HNO3.2TBP, and TBP.H2SO4 complexes.
Moreover, extraction of Iron(III) by TBP in HCl aqueous solution
forms complex FeCl3.TBP.2HCl while in HNO3 medium forms
complex 3FeCl3.TBP.2HNO3
Abstract: A Laboratory-scale packed bed reactor with microbial
cellulose as the biofilm carrier was used to investigate the
denitrification of high-strength nitrate wastewater with specific
emphasis on the effect the nitrogen loading rate and hydraulic
retention time. Ethanol was added as a carbon source for
denitrification. As a result of this investigation, it was found that up
to 500 mg/l feed nitrate concentration the present system is able to
produce an effluent with nitrate content below 10 ppm at 3 h
hydraulic retention time. The highest observed denitrification rate
was 4.57 kg NO3-N/ (m3 .d) at a nitrate load of 5.64 kg NO3-
N/(m3 .d), and removal efficiencies higher than 90% were obtained
for loads up to 4.2 kg NO3-N/(m3 .d). A mass relation between COD
consumed and NO3-N removed around 2.82 was observed. This
continuous-flow bioreactor proved an efficient denitrification system
with a relatively low retention time.
Abstract: In the last decade, carbohydrates have attracted great
attention as renewable resources for the chemical industry.
Carbohydrates are abundantly found in nature in the form of
monomers, oligomers and polymers, or as components of
biopolymers and other naturally occurring substances. As natural
products, they play important roles in conferring certain physical,
chemical, and biological properties to their carrier molecules.The
synthesis of this particular carbohydrate glycomonomer is part of our
work to obtain biodegradable polymers. Our current paper describes
the synthesis and characterization of a novel carbohydrate
glycomonomer starting from D-glucose, in several synthesis steps,
that involve the protection/deprotection of the D-glucose ring via
acetylation, tritylation, then selective deprotection of the aromaticaliphatic
protective group, in order to obtain 1,2,3,4-tetra-O-acetyl-
6-O-allyl-β-D-glucopyranose. The glycomonomer was then obtained
by the allylation in drastic conditions of 1,2,3,4-tetra-O-acetyl-6-Oallyl-
β-D-glucopyranose with allylic alcohol in the presence of
stannic chloride, in methylene chloride, at room temperature. The
proposed structure of the glycomonomer, 2,3,4-tri-O-acetyl-1,6-di-
O-allyl-β-D-glucopyranose, was confirmed by FTIR, NMR and
HPLC-MS spectrometry. This glycomonomer will be further
submitted to copolymerization with certain acrylic or methacrylic
monomers in order to obtain competitive plastic materials for
applications in the biomedical field.
Abstract: The goal of steganography is to avoid drawing
suspicion to the transmission of a hidden message. If suspicion is
raised, steganography may fail. The success of steganography
depends on the secrecy of the action. If steganography is detected,
the system will fail but data security depends on the robustness of the
applied algorithm. In this paper, we propose a novel plausible
deniability scheme in steganography by using a diversionary message
and encrypt it with a DES-based algorithm. Then, we compress the
secret message and encrypt it by the receiver-s public key along with
the stego key and embed both messages in a carrier using an
embedding algorithm. It will be demonstrated how this method can
support plausible deniability and is robust against steganalysis.
Abstract: Land with low pH soil spread widely in Indonesia
can be used for soybean (Glycine max) cultivation, however the
production is low. The use of acid tolerant soybean and acidaluminium
tolerant nitrogen-fixing bacteria formula was an
alternative way to increase soybean productivity on acid soils.
Bradyrhizobium japonicum is one of the nitrogen fixing bacteria
which can symbiose with soybean plants through root nodule
formation. Most of the nitrogen source required by soybean plants
can be provided by this symbiosis. This research was conducted to
study the influence of acid-aluminium tolerant B. japonicum strain
BJ 11 formula using peat as carrier on growth of Tanggamus and
Anjasmoro cultivar soybean planted on acid soil fields (pH 5.0-
5.5). The results showed that the inoculant was able to increase the
growth and production of soybean which were grown on fields acid
soil at Sukadana (Lampung) and Tanah Laut (South Kalimantan),
Indonesia.
Abstract: Linear stability analysis of wake-shear layers in twophase
shallow flows is performed in the present paper. Twodimensional
shallow water equations are used in the analysis. It is
assumed that the fluid contains uniformly distributed solid particles.
No dynamic interaction between the carrier fluid and particles is
expected in the initial moment. The stability calculations are
performed for different values of the particle loading parameter and
two other parameters which characterize the velocity ratio and the
velocity deficit. The results show that the particle loading parameter
has a stabilizing effect on the flow while the increase in the velocity
ratio or in the velocity deficit destabilizes the flow.
Abstract: In this paper, we propose a side-peak cancellation
scheme for code acquisition of composite binary offset carrier
(CBOC) signals. We first model the family of CBOC signals in a
generic form, and then, propose a side-peak cancellation scheme
by combining correlation functions between the divided sub-carrier
and received signals. From numerical results, it is shown that the
proposed scheme removes the side-peak completely, and moreover,
the resulting correlation function demonstrates the better power ratio
performance than the CBOC autocorrelation.
Abstract: Carriers scattering in the inversion channel of n-
MOSFET dominates the drain current. This paper presents an effective
electron mobility model for the pocket implanted nano scale
n-MOSFET. The model is developed by using two linear pocket
profiles at the source and drain edges. The channel is divided into
three regions at source, drain and central part of the channel region.
The total number of inversion layer charges is found for these three
regions by numerical integration from source to drain ends and the
number of depletion layer charges is found by using the effective
doping concentration including pocket doping effects. These two
charges are then used to find the effective normal electric field,
which is used to find the effective mobility model incorporating the
three scattering mechanisms, such as, Coulomb, phonon and surface
roughness scatterings as well as the ballistic phenomena for the
pocket implanted nano-scale n-MOSFET. The simulation results show
that the derived mobility model produces the same results as found
in the literatures.
Abstract: The InAlGaN alloy has only recently began receiving
serious attention into its growth and application. High quality InGaN
films have led to the development of light emitting diodes (LEDs) and
blue laser diodes (LDs). The quaternary InAlGaN however, represents
a more versatile material since the bandgap and lattice constant can be
independently varied. We report an ultraviolet (UV) quaternary
InAlGaN multi-quantum wells (MQWs) LD study by using the
simulation program of Integrated System Engineering (ISE TCAD).
Advanced physical models of semiconductor properties were used in
order to obtain an optimized structure. The device performance which
is affected by piezoelectric and thermal effects was studied via
drift-diffusion model for carrier transport, optical gain and loss. The
optical performance of the UV LD with different numbers of quantum
wells was numerically investigated. The main peak of the emission
wavelength for double quantum wells (DQWs) was shifted from 358
to 355.8 nm when the forward current was increased. Preliminary
simulated results indicated that better output performance and lower
threshold current could be obtained when the quantum number is four,
with output power of 130 mW and threshold current of 140 mA.
Abstract: power-line networks are promise infrastructure for
broadband services provision to end users. However, the network
performance is affected by stochastic channel changing which is due
to load impedances, number of branches and branched line lengths. It
has been proposed that multi-carrier modulations techniques such as
orthogonal frequency division multiplexing (OFDM), Multi-Carrier
Spread Spectrum (MC-SS), wavelet OFDM can be used in such
environment. This paper investigates the performance of different
indoor topologies of power-line networks that uses MC-SS
modulation scheme.It is observed that when a branch is added in the
link between sending and receiving end of an indoor channel an
average of 2.5dB power loss is found. In additional, when the branch
is added at a node an average of 1dB power loss is found.
Additionally when the terminal impedances of the branch change
from line characteristic impedance to impedance either higher or
lower values the channel performances were tremendously improved.
For example changing terminal load from characteristic impedance
(85 .) to 5 . the signal to noise ratio (SNR) required to attain the
same performances were decreased from 37dB to 24dB respectively.
Also, changing the terminal load from channel characteristic
impedance (85 .) to very higher impedance (1600 .) the SNR
required to maintain the same performances were decreased from
37dB to 23dB. The result concludes that MC-SS performs better
compared with OFDM techniques in all aspects and especially when
the channel is terminated in either higher or lower impedances.
Abstract: We present a novel construction of 16-QAM codewords of length n = 2k . The number of constructed codewords is 162×[4k-1×k-k+1] . When these constructed codewords are utilized as a code in OFDM systems, their peak-to-mean envelope power ratios (PMEPR) are bounded above by 3.6 . The principle of our scheme is illustrated with a four subcarrier example.
Abstract: This paper presents two different sequential switching hybrid-modulation strategies and implemented for cascaded multilevel inverters. Hybrid modulation strategies represent the combinations of Fundamental-frequency pulse width modulation (FFPWM) and Multilevel sinusoidal-modulation (MSPWM) strategies, and are designed for performance of the well-known Alternative Phase opposition disposition (APOD), Phase shifted carrier (PSC). The main characteristics of these modulations are the reduction of switching losses with good harmonic performance, balanced power loss dissipation among the devices with in a cell, and among the series-connected cells. The feasibility of these modulations is verified through spectral analysis, power loss analysis and simulation.
Abstract: Separation of propylene-propane mixture using
immobilized liquid membrane was investigated. The effect of transmembrane
pressure and carrier concentration on membrane
separation performance was studied. It was observed that for 30:70
(vol. %) propylene-propane mixture, at pressure of 120kPa and
carrier concentration of 20wt. %, a separation factor of 474 was
obtained.
Abstract: Poly-β-hydroxybutyrate (PHB) is one of the most
famous biopolymers that has various applications in production of
biodegradable carriers. The most important strategy for enhancing
efficiency in production process and reducing the price of PHB, is the
accurate expression of kinetic model of products formation and
parameters that are effective on it, such as Dry Cell Weight (DCW)
and substrate consumption. Considering the high capabilities of
artificial neural networks in modeling and simulation of non-linear
systems such as biological and chemical industries that mainly are
multivariable systems, kinetic modeling of microbial production of
PHB that is a complex and non-linear biological process, the three
layers perceptron neural network model was used in this study.
Artificial neural network educates itself and finds the hidden laws
behind the data with mapping based on experimental data, of dry cell
weight, substrate concentration as input and PHB concentration as
output. For training the network, a series of experimental data for
PHB production from Hydrogenophaga Pseudoflava by glucose
carbon source was used. After training the network, two other
experimental data sets that have not intervened in the network
education, including dry cell concentration and substrate
concentration were applied as inputs to the network, and PHB
concentration was predicted by the network. Comparison of predicted
data by network and experimental data, indicated a high precision
predicted for both fructose and whey carbon sources. Also in present
study for better understanding of the ability of neural network in
modeling of biological processes, microbial production kinetic of
PHB by Leudeking-Piret experimental equation was modeled. The
Observed result indicated an accurate prediction of PHB
concentration by artificial neural network higher than Leudeking-
Piret model.
Abstract: Here we report on the utilization of Laser-Induced
Breakdown Spectroscopy (LIBS) for determination of Quantum Dots
(QDs) in liquid solution. The process of optimization of experimental
conditions from choosing the carrier medium to application of colloid
QDs is described. The main goal was to get the best possible signal to
noise ratio.
The results obtained from the measurements confirmed the capability
of LIBS technique for qualitative and afterwards quantitative
determination of QDs in liquid solution.
Abstract: The paper shows some ability to manage two-phase
flows arising from the use of unsteady effects. In one case, we
consider the condition of fragmentation of the interface between the
two components leads to the intensification of mixing. The problem
is solved when the temporal and linear scale are small for the
appearance of the developed mixing layer. Showing that exist such
conditions for unsteady flow velocity at the surface of the channel,
which will lead to the creation and fragmentation of vortices at Re
numbers of order unity. Also showing that the Re is not a criterion of
similarity for this type of flows, but we can introduce a criterion that
depends on both the Re, and the frequency splitting of the vortices. It
turned out that feature of this situation is that streamlines behave
stable, and if we analyze the behavior of the interface between the
components it satisfies all the properties of unstable flows. The other
problem we consider the behavior of solid impurities in the extensive
system of channels. Simulated unsteady periodic flow modeled
breaths. Consider the behavior of the particles along the trajectories.
It is shown that, depending on the mass and diameter of the particles,
they can be collected in a caustic on the channel walls, stop in a
certain place or fly back. Of interest is the distribution of particle
velocity in frequency. It turned out that by choosing a behavior of the
velocity field of the carrier gas can affect the trajectory of individual
particles including force them to fly back.
Abstract: This work offers a study of new simple compact model
of dual-drain Magnetic Field Effect Transistor (MAGFET) including
geometrical effects and biasing dependency. An explanation of the
sensitivity is investigated, involving carrier deflection as the dominant
operating principle. Finally, model verification with simulation results
is introduced to ensure that acceptable error of 2% is achieved.
Abstract: Hydrogen is considered to be the most promising
candidate as a future energy carrier. One of the most used
technologies for the electrolytic hydrogen production is alkaline
water electrolysis. However, due to the high energy requirements, the
cost of hydrogen produced in such a way is high. In continuous
search to improve this process using advanced electrocatalytic
materials for the hydrogen evolution reaction (HER), Ni type Raney
and macro-porous Ni-Co electrodes were prepared on AISI 304
stainless steel substrates by electrodeposition. The developed
electrodes were characterized by SEM and confocal laser scanning
microscopy. HER on these electrodes was evaluated in 30 wt.% KOH
solution by means of hydrogen discharge curves and galvanostatic
tests. Results show that the developed electrodes present a most
efficient behaviour for HER when comparing with the smooth Ni
cathode. It has been reported a reduction in the energy consumption
of the electrolysis cell of about 25% by using the developed coatings
as cathodes.