Abstract: In-vitro mouse co-culture of E14 embryonic stem cells
(ESCs) and OP9 stromal cells can recapitulate the earliest stages of
haematopoietic development, not accessible in human embryos,
supporting both haemogenic precursors and their primitive
haematopoietic progeny. 1α, 25-Dihydroxy-vitamin D3 (VD3) has
been demonstrated to be a powerful differentiation inducer for a wide
variety of neoplastic cells, and could enhance early differentiation of
ESCs into blood cells in E14/OP9 co-culture. This study aims to
ascertain whether VD3 is key in promoting differentiation and
suppressing proliferation, by separately investigating the effects of
VD3 on the proliferation phase of the E14 cell line and on stromal
OP9 cells.The results showed that VD3 inhibited the proliferation of
the cells in a dose-dependent manner, quantitatively by decreased cell
number, and qualitatively by alkaline-phosphatase staining that
revealed significant differences between VD3-treated and untreated
cells, characterised by decreased enzyme expression (colourless
cells). Propidium-iodide cell-cycle analyses showed no significant
percentage change in VD3-treated E14 and OP9 cells within their G
and S-phases, compared to the untreated controls, despite the
increased percentage of G-phase compared to the S-phase in a dosedependent
manner. These results with E14 and OP9 cells indicate that
adequate VD3 concentration enhances cellular differentiation and
inhibits proliferation. The results also suggest that if E14 and OP9
cells were co-cultured andVD3-treated, there would be furtherenhanced
differentiation of ESCs into blood cells.
Abstract: This paper presents a method for determining the
uniaxial tensile properties such as Young-s modulus, yield strength
and the flow behaviour of a material in a virtually non-destructive
manner. To achieve this, a new dumb-bell shaped miniature
specimen has been designed. This helps in avoiding the removal of
large size material samples from the in-service component for the
evaluation of current material properties. The proposed miniature
specimen has an advantage in finite element modelling with respect
to computational time and memory space. Test fixtures have been
developed to enable the tension tests on the miniature specimen in a
testing machine. The studies have been conducted in a chromium
(H11) steel and an aluminum alloy (AR66). The output from the
miniature test viz. load-elongation diagram is obtained and the finite
element simulation of the test is carried out using a 2D plane stress
analysis. The results are compared with the experimental results. It is
observed that the results from the finite element simulation
corroborate well with the miniature test results. The approach seems
to have potential to predict the mechanical properties of the
materials, which could be used in remaining life estimation of the
various in-service structures.
Abstract: This paper explores the knowledge and attitude of
women and men in decision making on pap smear screening. This
qualitative study recruited 52 respondents with 44 women and 8 men,
using the purposive sampling with snowballing technique through indepth
interviews. This study demonstrates several key findings:
Female respondents have better knowledge compared to male. Most
of the women perceived that pap smear screening is beneficial and
important, but to proceed with the test is still doubtful. Male
respondents were supportive in terms of sending their spouses to the
health facilities or give more freedom to their wives to choose and
making decision on their own health due to prominent reason that
women know best on their own health. It is expected that the results
from this study will provide useful guideline for healthcare providers
to prepare any action/intervention to provide an extensive education
to improve people-s knowledge and attitude towards pap smear.
Abstract: During recent years wind turbine technology has
undergone rapid developments. Growth in size and the optimization
of wind turbines has enabled wind energy to become increasingly
competitive with conventional energy sources. As a result today-s
wind turbines participate actively in the power production of several
countries around the world. These developments raise a number of
challenges to be dealt with now and in the future. The penetration of
wind energy in the grid raises questions about the compatibility of the
wind turbine power production with the grid. In particular, the
contribution to grid stability, power quality and behavior during fault
situations plays therefore as important a role as the reliability. In the
present work, we addressed two fault situations that have shown their
influence on the generator and the behavior of the wind over the
defects which are briefly discussed based on simulation results.
Abstract: In this study, the contact problem of a layered composite which consists of two materials with different elastic constants and heights resting on two rigid flat supports with sharp edges is considered. The effect of gravity is neglected. While friction between the layers is taken into account, it is assumed that there is no friction between the supports and the layered composite so that only compressive tractions can be transmitted across the interface. The layered composite is subjected to a uniform clamping pressure over a finite portion of its top surface. The problem is reduced to a singular integral equation in which the contact pressure is the unknown function. The singular integral equation is evaluated numerically and the results for various dimensionless quantities are presented in graphical forms.
Abstract: In this paper, all-optical signal processors that perform
both microwave mixing and bandpass filtering in a radio-over-fiber
(RoF) link are presented. The key device is a Mach-Zehnder
modulator (MZM) which performs all-optical microwave mixing. An
up-converted microwave signal is obtained and other unwanted
frequency components are suppressed at the end of the fiber span.
Abstract: Ethanol has been known for a long time, being
perhaps the oldest product obtained through traditional biotechnology
fermentation. Agriculture waste as substrate in fermentation is vastly
discussed as alternative to replace edible food and utilization of
organic material. Pineapple peel, highly potential source as substrate
is a by-product of the pineapple processing industry. Bio-ethanol
from pineapple (Ananas comosus) peel extract was carried out by
controlling fermentation without any treatment. Saccharomyces
ellipsoides was used as inoculum in this fermentation process as it is
naturally found at the pineapple skin. In this study, the capability of
Response Surface Methodology (RSM) for optimization of ethanol
production from pineapple peel extract using Saccharomyces
ellipsoideus in batch fermentation process was investigated. Effect of
five test variables in a defined range of inoculum concentration 6-
14% (v/v), pH (4.0-6.0), sugar concentration (14-22°Brix),
temperature (24-32°C) and time of incubation (30-54 hrs) on the
ethanol production were evaluated. Data obtained from experiment
were analyzed with RSM of MINITAB Software (Version 15)
whereby optimum ethanol concentration of 8.637% (v/v) was
determined. The optimum condition of 14% (v/v) inoculum
concentration, pH 6, 22°Brix, 26°C and 30hours of incubation. The
significant regression equation or model at the 5% level with
correlation value of 99.96% was also obtained.
Abstract: The paper proposes the novel design of a 3T XOR gate combining complementary CMOS with pass transistor logic. The design has been compared with earlier proposed 4T and 6T XOR gates and a significant improvement in silicon area and power-delay product has been obtained. An eight transistor full adder has been designed using the proposed three-transistor XOR gate and its performance has been investigated using 0.15um and 0.35um technologies. Compared to the earlier designed 10 transistor full adder, the proposed adder shows a significant improvement in silicon area and power delay product. The whole simulation has been carried out using HSPICE.
Abstract: The paper describes the evaluation of quality of
control for cases of controlled non-minimal phase plants. Control
circuits containing non-minimal phase plants have different
properties, they manifest reversed reaction at the beginning of unit
step response. For these types of plants are developed special
criterion of quality of control, which considers the difference and can
be helpful for synthesis of optimal controller tuning. All results are
clearly presented using Matlab/Simulink models.
Abstract: Positron emission particle tracking (PEPT) is a
technique in which a single radioactive tracer particle can be
accurately tracked as it moves. A limitation of PET is that in order to
reconstruct a tomographic image it is necessary to acquire a large
volume of data (millions of events), so it is difficult to study rapidly
changing systems. By considering this fact, PEPT is a very fast
process compared with PET.
In PEPT detecting both photons defines a line and the annihilation
is assumed to have occurred somewhere along this line. The location
of the tracer can be determined to within a few mm from coincident
detection of a small number of pairs of back-to-back gamma rays and
using triangulation. This can be achieved many times per second and
the track of a moving particle can be reliably followed. This
technique was invented at the University of Birmingham [1].
The attempt in PEPT is not to form an image of the tracer particle
but simply to determine its location with time. If this tracer is
followed for a long enough period within a closed, circulating system
it explores all possible types of motion.
The application of PEPT to industrial process systems carried out
at the University of Birmingham is categorized in two subjects: the
behaviour of granular materials and viscous fluids. Granular
materials are processed in industry for example in the manufacture of
pharmaceuticals, ceramics, food, polymers and PEPT has been used
in a number of ways to study the behaviour of these systems [2].
PEPT allows the possibility of tracking a single particle within the
bed [3]. Also PEPT has been used for studying systems such as: fluid
flow, viscous fluids in mixers [4], using a neutrally-buoyant tracer
particle [5].
Abstract: Social, culture and artistic status of a society in
various historical eras is affected by numerous, and sometimes
imposed, factors that better understanding requires analysis of such
conditions. Throughout history Iran has been involved with
determining and significant events that examining each of these
events can improve the understanding of social conditions of this
country in the intended time. Mongolian conquest of Iran is one of
most significant events in the history of Iran with consequences that
never left Iranian societies. During this tragic invasion and
subsequent devastating wars, which led to establishment of Ilkhanate
dynasty, numerous cultural and artistic changes occurred both in
Mongolian conquerors and Iranian society. This study examines these
changes with a glimpse towards art and architecture as important part
of cultural aspects and social communication.
Abstract: In a bi-fuel diesel engine, the carburetor plays a vital
role in switching from fuel gas to petrol mode operation and viceversa.
The carburetor is the most important part of the fuel system of
a diesel engine. All diesel engines carry variable venturi mixer
carburetors. The basic operation of the carburetor mainly depends on
the restriction barrel called the venturi. When air flows through the
venturi, its speed increases and its pressure decreases. The main
challenge focuses on designing a mixing device which mixes the
supplied gas is the incoming air at an optimum ratio. In order to
surmount the identified problems, the way fuel gas and air flow in
the mixer have to be analyzed. In this case, the Computational Fluid
Dynamics or CFD approach is applied in design of the prototype
mixer. The present work is aimed at further understanding of the air
and fuel flow structure by performing CFD studies using a software
code. In this study for mixing air and gas in the condition that has
been mentioned in continuance, some mixers have been designed.
Then using of computational fluid dynamics, the optimum mixer has
been selected. The results indicated that mixer with 12 holes can
produce a homogenous mixture than those of 8-holes and 6-holes
mixer. Also the result showed that if inlet convergency was smoother
than outlet divergency, the mixture get more homogenous, the reason
of that is in increasing turbulence in outlet divergency.
Abstract: Vapour recompression system has been used to
enhance reduction in energy consumption and improvement in
energy effectiveness of distillation columns. However, the effects of
certain parameters have not been taken into consideration. One of
such parameters is the column heat loss which has either been
assumed to be a certain percent of reboiler heat transfer or negligible.
The purpose of this study was to evaluate the heat loss from an
ethanol-water vapour recompression distillation column with
pressure increase across the compressor (VRCAS) and compare the
results obtained and its effect on some parameters in similar system
(VRCCS) where the column heat loss has been assumed or neglected.
Results show that the heat loss evaluated was higher when compared
with that obtained for the column VRCCS. The results also showed
that increase in heat loss could have significant effect on the total
energy consumption, reboiler heat transfer, the number of trays and
energy effectiveness of the column.
Abstract: Most paddy rice fields in East Asia are small parcels,
and the weather conditions during the growing season are usually
cloudy. FORMOSAT-2 multi-spectral images have an 8-meter
resolution and one-day recurrence, ideal for mapping paddy rice fields
in East Asia. To map rice fields, this study first determined the
transplanting and the most active tillering stages of paddy rice and
then used multi-temporal images to distinguish different growing
characteristics between paddy rice and other ground covers. The
unsupervised ISODATA (iterative self-organizing data analysis
techniques) and supervised maximum likelihood were both used to
discriminate paddy rice fields, with training areas automatically
derived from ten-year cultivation parcels in Taiwan. Besides original
bands in multi-spectral images, we also generated normalized
difference vegetation index and experimented with object-based
pre-classification and post-classification. This paper discusses results
of different image classification methods in an attempt to find a
precise and automatic solution to mapping paddy rice in Taiwan.
Abstract: The production of activated carbon from low or zero cost of agricultural by-products or wastes has received great attention from academics and practitioners due to its economic and environmental benefits. In the production of bamboo furniture, a significant amount of bamboo waste is inevitably generated. Therefore, this research aimed to prepare activated carbons from bamboo furniture waste by chemical (KOH) activation and determine their properties and adsorption capacities for water treatment. The influence of carbonization time on the properties and adsorption capacities of activated carbons was also investigated. The finding showed that the bamboo-derived activated carbons had microporous characteristics. They exhibited high tendency for the reduction of impurities present in effluent water. Their adsorption capacities were comparable to the adsorption capacity of a commercial activated carbon regarding to the reduction in COD, TDS and turbidity of the effluent water.
Abstract: TiO2 supported nano-ZnO catalyst was prepared by
deposition-precipitation and tested for the trans-esterification
reaction of soybean oil to biodiesel. The TiO2 support stabilized the
nano-ZnO in a dispersed form with limited crystallite size compared
to the unsupported ZnO. The final ZnO dispersion and crystallite size
and the material transfer resistance in the catalyst significantly
influenced the supported nano-ZnO catalyst performance.
Abstract: Traffic density, an indicator of traffic
conditions, is one of the most critical characteristics to
Intelligent Transport Systems (ITS). This paper investigates
recursive traffic density estimation using the information
provided from inductive loop detectors. On the basis of the
phenomenological relationship between speed and density, the
existing studies incorporate a state space model and update the
density estimate using vehicular speed observations via the
extended Kalman filter, where an approximation is made
because of the linearization of the nonlinear observation
equation. In practice, this may lead to substantial estimation
errors. This paper incorporates a suitable transformation to
deal with the nonlinear observation equation so that the
approximation is avoided when using Kalman filter to
estimate the traffic density. A numerical study is conducted. It
is shown that the developed method outperforms the existing
methods for traffic density estimation.
Abstract: Text categorization techniques are widely used to many Information Retrieval (IR) applications. In this paper, we proposed a simple but efficient method that can automatically find the relationship between any pair of terms and documents, also an indexing matrix is established for text categorization. We call this method Indexing Matrix Categorization Machine (IMCM). Several experiments are conducted to show the efficiency and robust of our algorithm.
Abstract: Tourism is a phenomenon respected by the human communities since a long time ago. It has been evoloving continually based on a variety of social and economic needs and with respect to increasingly development of communication and considerable increase of tourist-s number and resulted exchange income has attained much out come such as employment for the communities. or the purpose of tourism development in this zone suitable times and locations need to be specified in the zone for the tourist-s attendance. One of the most important needs of the tourists is the knowledge of climate conditions and suitable times for sightseeing. In this survey, the climate trend condition has been identified for attending the tourists in Isfahan province using the modified tourism climate index (TCI) as well as SPSS, GIS, excel, surfer softwares. This index evoluates systematically the climate conditions for tourism affairs and activities using the monthly maximum mean parameters of daily temperature, daily mean temperature, minimum relative humidity, daily mean relative humidity, precipitation (mm), total sunny hours, wind speed and dust. The results obtaind using kendal-s correlation test show that the months January, February, March, April, May, June, July, August, September, October, November and December are significant and have an increasing trend that indicates the best condition for attending the tourists. S, P, T mean , T max and dust are estimated from 1976-2005 and do kendal-s correlation test again to see which parameter has been effective. Based on the test, we also observed on the effective parameters that the rate of dust in February, March, April, May, June, July, August, October and November is decreasing and precipitation in September and January is increasing and also the radiation rate in May and August is increasing that indicate a better condition of convenience. Maximum temperature in June is also decreasing. Isfahan province has two spring and fall peaks and the best places for tourism are in the north and western areas.
Abstract: This paper presented a proposed design for
transcutaneous inductive powering links. The design used to transfer
power and data to the implanted devices such as implanted
Microsystems to stimulate and monitoring the nerves and muscles.
The system operated with low band frequency 13.56 MHZ according
to industrial- scientific – medical (ISM) band to avoid the tissue
heating. For external part, the modulation index is 13 % and the
modulation rate 7.3% with data rate 1 Mbit/s assuming Tbit=1us. The
system has been designed using 0.35-μm fabricated CMOS
technology. The mathematical model is given and the design is
simulated using OrCAD P Spice 16.2 software tool and for real-time
simulation the electronic workbench MULISIM 11 has been used.
The novel circular plane (pancake) coils was simulated using
ANSOFT- HFss software.