Abstract: Heat-inducible gene expression vectors are useful for hyperthermia-induced cancer gene therapy, because the combination
of hyperthermia and gene therapy can considerably improve the therapeutic effects. In the present study, we developed an enhanced
heat-inducible transgene expression system in which a heat-shock
protein (HSP) promoter and tetracycline-responsive transactivator
were combined. When the transactivator plasmid containing the
tetracycline-responsive transactivator gene was co-transfected with
the reporter gene expression plasmid, a high level of heat-induced gene expression was observed compared with that using the HSP
promoter without the transactivator. In vitro evaluation of the
therapeutic effect using HeLa cells showed that heat-induced therapeutic gene expression caused cell death in a high percentage of
these cells, indicating that this strategy is promising for cancer gene therapy.
Abstract: In this paper, we present local image descriptor using
VQ-SIFT for more effective and efficient image retrieval. Instead of
SIFT's weighted orientation histograms, we apply vector quantization
(VQ) histogram as an alternate representation for SIFT features.
Experimental results show that SIFT features using VQ-based local
descriptors can achieve better image retrieval accuracy than the
conventional algorithm while the computational cost is significantly
reduced.
Abstract: This study examines the possibility to apply the theory of multidimensional accounting (momentum accounting) in a Brazilian Navy-s Services Provider Military Organization (Organização Militar Prestadora de Serviços - OMPS). In general, the core of the said theory is the fact that Accounting does not recognize the inertia of transactions occurring in an entity, and that occur repeatedly in some cases, regardless of the implementation of new actions by its managers. The study evaluates the possibility of greater use of information recorded in the financial statements of the unit of analysis, within the strategic decisions of the organization. As a research strategy, we adopted the case study. The results infer that it is possible to use the theory in the context of a multidimensional OMPS, promoting useful information for decision-making and thereby contributing to the strengthening of the necessary alignment of its administration with the current desires of the Brazilian society.
Abstract: Recent theorizations on the cognitive process of moral
judgment have focused on the role of intuitions and emotions, marking
a departure from previous emphasis on conscious, step-by-step
reasoning. My study investigated how being in a disgusted mood state
affects moral judgment.
Participants were induced to enter a disgusted mood state through
listening to disgusting sounds and reading disgusting descriptions.
Results shows that they, when compared to control who have not been
induced to feel disgust, are more likely to endorse actions that are
emotionally aversive but maximizes utilitarian return
The result is analyzed using the 'emotion-as-information' approach
to decision making. The result is consistent with the view that
emotions play an important role in determining moral judgment.
Abstract: High quality requirements analysis is one of the most
crucial activities to ensure the success of a software project, so that
requirements verification for software system becomes more and more
important in Requirements Engineering (RE) and it is one of the most
helpful strategies for improving the quality of software system.
Related works show that requirement elicitation and analysis can be
facilitated by ontological approaches and semantic web technologies.
In this paper, we proposed a hybrid method which aims to verify
requirements with structural and formal semantics to detect
interactions. The proposed method is twofold: one is for modeling
requirements with the semantic web language OWL, to construct a
semantic context; the other is a set of interaction detection rules which
are derived from scenario-based analysis and represented with
semantic web rule language (SWRL). SWRL based rules are working
with rule engines like Jess to reason in semantic context for
requirements thus to detect interactions. The benefits of the proposed
method lie in three aspects: the method (i) provides systematic steps
for modeling requirements with an ontological approach, (ii) offers
synergy of requirements elicitation and domain engineering for
knowledge sharing, and (3)the proposed rules can systematically assist
in requirements interaction detection.
Abstract: Work stress causes the organizational work-life
imbalance of employees. Because of this imbalance, workers perform
with lower effort to finish assignments and thus an organization will
experience reduced productivity. In order to investigate the problem
of an organizational work-life imbalance, this qualitative case study
focuses on an organizational work-life imbalance among Thai
software developers in a German-owned company in Chiang Mai,
Thailand. In terms of knowledge management, fishbone diagram is
useful analysis tool to investigate the root causes of an organizational
work-life imbalance systematically in focus-group discussions.
Furthermore, fishbone diagram shows the relationship between
causes and effects clearly. It was found that an organizational worklife
imbalance among Thai software developers is influenced by
management team, work environment, and information tools used in
the company over time.
Abstract: The effect of wheat flour extraction rates on flour
composition, farinographic characteristics and the quality of
sourdough naans was investigated. The results indicated that by
increasing the extraction rate, the amount of protein, fiber, fat and
ash increased, whereas moisture content decreased. Farinographic
characteristic like water absorption and dough development time
increased with an increase in flour extraction rate but the dough
stabilities and tolerance indices were reduced with an increase in
flour extraction rates. Titratable acidity for both sourdough and
sourdough naans also increased along with flour extraction rate. The
study showed that overall quality of sourdough naans were affected
by both flour extraction rate and starter culture used. Sensory
analysis of sourdough naans revealed that desirable extraction rate
for sourdough naan was 76%.
Abstract: In this study, the effect of nanofluids on the pool film
boiling was experimentally investigated at saturated condition under
atmospheric pressure. For this purpose, four different water-based
nanofluids (Al2O3, SiO2, TiO2 and CuO) with 0.1% particle volume
fraction were prepared. To investigate the boiling heat transfer, a
cylindrical rod with high temperature was used. The rod heated up to
high temperatures was immersed into nanofluids. The center
temperature of rod during the cooling process was recorded by using
a K-type thermocouple. The quenching curves showed that the pool
boiling heat transfer was strongly dependent on the nanoparticle
materials. During the repetitive quenching tests, the cooling time
decreased and thus, the film boiling vanished. Consequently, the
primary reason of this was the change of the surface characteristics
due to the nanoparticles deposition on the rod-s surface.
Abstract: Groundwater has become the most dependable source
of fresh water for agriculture, domestic and industrial uses in the past
few decades. This wide use of groundwater if left uncontrolled and
unseen will lead to overexploitation causing sea water intrusion in the
coastal areas and illegal water marketing. Several Policies and Acts
have been enacted to regulate and manage the use of this valuable
resource. In spite of this the over extraction of groundwater beyond
the recharging capacity of aquifers and depletion in the quality of
groundwater is continuing. The current study aims at reviewing the
Acts and Policies existing in the State of Tamil Nadu and in the
National level regarding groundwater regulation and management.
Further an analysis is made on the rights associated with the usage of
groundwater resources and the gaps in these policies have been
analyzed. Some suggestions are made to reform the existing
groundwater policies for better management and regulation of the
resource.
Abstract: In this paper, a new formulation for acoustics coupled with linear elasticity is presented. The primary objective of the work is to develop a three dimensional hp adaptive finite element method code destinated for modeling of acoustics of human head. The code will have numerous applications e.g. in designing hearing protection devices for individuals working in high noise environments. The presented work is in the preliminary stage. The variational formulation has been implemented and tested on a sequence of meshes with concentric multi-layer spheres, with material data representing the tissue (the brain), skull and the air. Thus, an efficient solver for coupled elasticity/acoustics problems has been developed, and tested on high contrast material data representing the human head.
Abstract: There have been different approaches to compute the
analytic instantaneous frequency with a variety of background reasoning
and applicability in practice, as well as restrictions. This paper presents an adaptive Fourier decomposition and (α-counting) based
instantaneous frequency computation approach. The adaptive Fourier
decomposition is a recently proposed new signal decomposition
approach. The instantaneous frequency can be computed through the so called mono-components decomposed by it. Due to the fast energy
convergency, the highest frequency of the signal will be discarded by the adaptive Fourier decomposition, which represents the noise of
the signal in most of the situation. A new instantaneous frequency
definition for a large class of so-called simple waves is also proposed
in this paper. Simple wave contains a wide range of signals for which
the concept instantaneous frequency has a perfect physical sense.
The α-counting instantaneous frequency can be used to compute the highest frequency for a signal. Combination of these two approaches one can obtain the IFs of the whole signal. An experiment is demonstrated the computation procedure with promising results.
Abstract: This paper describes an optimal approach for feature
subset selection to classify the leaves based on Genetic Algorithm
(GA) and Kernel Based Principle Component Analysis (KPCA). Due
to high complexity in the selection of the optimal features, the
classification has become a critical task to analyse the leaf image
data. Initially the shape, texture and colour features are extracted
from the leaf images. These extracted features are optimized through
the separate functioning of GA and KPCA. This approach performs
an intersection operation over the subsets obtained from the
optimization process. Finally, the most common matching subset is
forwarded to train the Support Vector Machine (SVM). Our
experimental results successfully prove that the application of GA
and KPCA for feature subset selection using SVM as a classifier is
computationally effective and improves the accuracy of the classifier.
Abstract: The thermal, epithermal and fast fluxes were
calculated for three irradiation channels at Egypt Second Research
Reactor (ETRR-2) using CITVAP code. The validity of the
calculations was verified by experimental measurements. There are
some deviations between measurements and calculations. This is due
to approximations in the calculation models used, homogenization of
regions, condensation of energy groups and uncertainty in nuclear
data used. Neutron flux data for the three irradiation channels are
now available. This would enable predicting the irradiation
conditions needed for future radioisotope production.
Abstract: Several studies have shown the association between
ambient particulate matter (PM) and adverse health effects and
climate change, thus highlighting the need to limit the anthropogenic
sources of PM. PM Exposure is commonly monitored as mass
concentration of PM10 (particle aerodynamic diameter < 10μm) or
PM2.5 (particle aerodynamic diameter < 2.5μm), although increasing
toxicity with decreasing aerodynamic diameter has been reported due
to increased surface area and enhanced chemical reactivity with other
species. Additionally, the light scattering properties of PM increases
with decreasing size. Hence, it is important to study the chemical
characterization of finer fraction of the particulate matter and to
identify their sources so that they can be controlled appropriately to a
large extent at the sources before reaching to the receptors.
Abstract: Creep stresses and strain rates have been obtained
for a thin rotating disc having variable density with inclusion by
using Seth-s transition theory. The density of the disc is assumed to
vary radially, i.e. ( ) 0 ¤ü ¤ü r/b m - = ; ¤ü 0 and m being real positive
constants. It has been observed that a disc, whose density increases
radially, rotates at higher angular speed, thus decreasing the
possibility of a fracture at the bore, whereas for a disc whose
density decreases radially, the possibility of a fracture at the bore
increases.
Abstract: The hypercube Qn is one of the most well-known
and popular interconnection networks and the k-ary n-cube Qk
n is
an enlarged family from Qn that keeps many pleasing properties
from hypercubes. In this article, we study the panpositionable
hamiltonicity of Qk
n for k ≥ 3 and n ≥ 2. Let x, y of V (Qk
n)
be two arbitrary vertices and C be a hamiltonian cycle of Qk
n.
We use dC(x, y) to denote the distance between x and y on the
hamiltonian cycle C. Define l as an integer satisfying d(x, y) ≤ l ≤ 1
2 |V (Qk
n)|. We prove the followings:
• When k = 3 and n ≥ 2, there exists a hamiltonian cycle C
of Qk
n such that dC(x, y) = l.
• When k ≥ 5 is odd and n ≥ 2, we request that l /∈ S
where S is a set of specific integers. Then there exists a
hamiltonian cycle C of Qk
n such that dC(x, y) = l.
• When k ≥ 4 is even and n ≥ 2, we request l-d(x, y) to be
even. Then there exists a hamiltonian cycle C of Qk
n such
that dC(x, y) = l.
The result is optimal since the restrictions on l is due to the
structure of Qk
n by definition.
Abstract: In this study we investigate silica nanoparticle (SiO2- NP) effects on the structure and phase properties of supported lipid monolayers and bilayers, coupling surface pressure measurements, fluorescence microscopy and atomic force microscopy. SiO2-NPs typically in size range of 10nm to 100 nm in diameter are tested. Our results suggest first that lipid molecules organization depends to their nature. Secondly, lipid molecules in the vinicity of big aggregates nanoparticles organize in liquid condensed phase whereas small aggregates are localized in both fluid liquid-expanded (LE) and liquid-condenced (LC). We demonstrated also by atomic force microscopy that by measuring friction forces it is possible to get information as if nanoparticle aggregates are recovered or not by lipid monolayers and bilayers.
Abstract: A zero-field ferromagnetic Ising model is utilized to
simulate the propagation of infection in a population that assumes a
square lattice structure. The rate of infection increases with
temperature. The disease spreads faster among individuals with low J
values. Such effect, however, diminishes at higher temperatures.
Abstract: The group mutual exclusion (GME) problem is a
variant of the mutual exclusion problem. In the present paper a
token-based group mutual exclusion algorithm, capable of handling
transient faults, is proposed. The algorithm uses the concept of
dynamic request sets. A time out mechanism is used to detect the
token loss; also, a distributed scheme is used to regenerate the token.
The worst case message complexity of the algorithm is n+1. The
maximum concurrency and forum switch complexity of the
algorithm are n and min (n, m) respectively, where n is the number of
processes and m is the number of groups. The algorithm also satisfies
another desirable property called smooth admission. The scheme can
also be adapted to handle the extended group mutual exclusion
problem.
Abstract: This paper describes how the correct endian mode of
the TMS320C6713 DSK board can be identified. It also explains how
the TMS320C6713 DSK board can be used in the little endian and in
the big endian modes for assembly language programming in
particular and for signal processing in general. Similarly, it discusses
how crucially important it is for a user of the TMS320C6713 DSK
board to identify the mode of operation and then use it correctly
during the development stages of the assembly language
programming; otherwise, it will cause unnecessary confusion and
erroneous results as far as storing data into the memory and loading
data from the memory is concerned. Furthermore, it highlights and
strongly recommends to the users of the TMS320C6713 DSK board
to be aware of the availability and importance of various display
options in the Code Composer Studio (CCS) for correctly
interpreting and displaying the desired data in the memory. The
information presented in this paper will be of great importance and
interest to those practitioners and developers who wants to use the
TMS320C6713 DSK board for assembly language programming as
well as input-output signal processing manipulations. Finally,
examples that clearly illustrate the concept are presented.