Phase Behavior and Structure Properties of Supported Lipid Monolayers and Bilayers in Interaction with Silica Nanoparticles
In this study we investigate silica nanoparticle (SiO2- NP) effects on the structure and phase properties of supported lipid monolayers and bilayers, coupling surface pressure measurements, fluorescence microscopy and atomic force microscopy. SiO2-NPs typically in size range of 10nm to 100 nm in diameter are tested. Our results suggest first that lipid molecules organization depends to their nature. Secondly, lipid molecules in the vinicity of big aggregates nanoparticles organize in liquid condensed phase whereas small aggregates are localized in both fluid liquid-expanded (LE) and liquid-condenced (LC). We demonstrated also by atomic force microscopy that by measuring friction forces it is possible to get information as if nanoparticle aggregates are recovered or not by lipid monolayers and bilayers.
[1] Nel, A., et al., Toxic Potential of Materials at the Nanolevel. Science,
2006. 311(5761): p. 622-627.
[2] Leroueil, P.R., et al., Wide Varieties of Cationic Nanoparticles Induce
Defects in Supported Lipid Bilayers. Nano Letters, 2008. 8(2): p. 420-
424.
[3] Jose Ruben, M., et al., The bactericidal effect of silver nanoparticles.
Nanotechnology, 2005. 16(10): p. 2346.
[4] Roiter, Y., et al., Interaction of Nanoparticles with Lipid Membrane.
Nano Letters, 2008. 8(3): p. 941-944.
[5] Li, Y., X. Chen, and N. Gu, Computational Investigation of Interaction
between Nanoparticles and Membranes: Hydrophobic/Hydrophilic
Effect. The Journal of Physical Chemistry B, 2008. 112(51): p. 16647-
16653.
[6] Arvizo, R.R., et al., Effect of Nanoparticle Surface Charge at the
Plasma Membrane and Beyond. Nano Letters, 2010. 10(7): p. 2543-
2548.
[7] Limbach, L.K., et al., Oxide Nanoparticle Uptake in Human Lung
Fibroblasts: Effects of Particle Size, Agglomeration, and Diffusion at
Low Concentrations. Environmental Science & Technology, 2005.
39(23): p. 9370-9376.
[8] Pujalté, I., et al., Cytotoxicity and oxidative stress induced by different
metallic nanoparticles on human kidney cells. Particle and Fibre
Toxicology, 2011. 8(1): p. 1-16.
[9] Coccini, T., et al., Apoptosis induction and histological changes in rat
kidney following Cd-doped silica nanoparticle exposure: evidence of
persisting effects. Toxicology Mechanisms and Methods, 2013: p. 1-27.
[10] Yong, K.-T., et al., Nanotoxicity assessment of quantum dots: from
cellular to primate studies. Chemical Society Reviews, 2013. 42(3): p.
1236-1250.
[11] Sonnino, S. and A. Prinetti, Membrane Domains and the Lipid Raft
Concept. Current Medicinal Chemistry, 2013. 20(1): p. 4-21.
[12] Li, M., et al., AFM Studies of Solid-Supported Lipid Bilayers Formed at
a Au(111) Electrode Surface Using Vesicle Fusion and a Combination
of Langmuir−Blodgett and Langmuir−Schaefer Techniques. Langmuir,
2008. 24(18): p. 10313-10323.
[13] Giocondi, M.-C., et al., Remodeling of Ordered Membrane Domains by
GPI-Anchored Intestinal Alkaline Phosphatase. Langmuir, 2007.
23(18): p. 9358-9364.
[14] Richter, R.P., R. Bérat, and A.R. Brisson, Formation of Solid-Supported
Lipid Bilayers: An Integrated View. Langmuir, 2006. 22(8): p. 3497-
3505.
[15] Faye, N.R., et al., Oxidation of Langmuir–Blodgett films of
monounsaturated lipids studied by atomic force microscopy.
International Journal of Nanotechnology, 2013. 10(5): p. 390-403.
[16] Morandat, S., et al., Atomic force microscopy of model lipid membranes.
Analytical and Bioanalytical Chemistry, 2013. 405(5): p. 1445-1461.
[17] El Kirat, K., S. Morandat, and Y.F. Dufrêne, Nanoscale analysis of
supported lipid bilayers using atomic force microscopy. Biochimica et
Biophysica Acta (BBA) - Biomembranes, 2010. 1798(4): p. 750-765.
[18] Mingeot-Leclercq, M.-P., et al., Atomic force microscopy of supported
lipid bilayers. Nat. Protocols, 2008. 3(10): p. 1654-1659.
[19] Bouhacina, T., et al., Oscillation of the cantilever in atomic force
microscopy: Probing the sample response at the microsecond scale.
Journal of Applied Physics, 1997. 82(8): p. 3652-3660.
[20] Gauthier, S., et al., Study of Grafted Silane Molecules on Silica Surface
with an Atomic Force Microscope. Langmuir, 1996. 12(21): p. 5126-
5137.
[21] Bouhacina, T., B. Desbat, and J.P. Aimé, FTIR spectroscopy and
nanotribological comparative studies: influence of the adsorbed water
layers on the tribological behaviour. Tribology Letters, 2000. 9(1-2): p.
111-117.
[22] Kopp-Marsaudon, S., et al., Quantitative Measurement of the
Mechanical Contribution to Tapping-Mode Atomic Force Microscopy
Images of Soft Materials. Langmuir, 2000. 16(22): p. 8432-8437.
[23] Parthasarathy, R., C.-h. Yu, and J.T. Groves, Curvature-Modulated
Phase Separation in Lipid Bilayer Membranes. Langmuir, 2006. 22(11):
p. 5095-5099.
[24] Holopainen, J.M., et al., Interfacial Interactions of Ceramide with
Dimyristoylphosphatidylcholine: Impact of the N-Acyl Chain.
Biophysical Journal, 2001. 80(2): p. 765-775.
[25] Grauby-Heywang, C. and J.-M. Turlet, Behavior of GM3 ganglioside in
lipid monolayers mimicking rafts or fluid phase in membranes.
Chemistry and Physics of Lipids, 2006. 139(1): p. 68-76.
[26] Azouzi, S., K. El Kirat, and S. Morandat, The Potent Antimalarial Drug
Cyclosporin A Preferentially Destabilizes Sphingomyelin-Rich
Membranes. Langmuir, 2009. 26(3): p. 1960-1965.
[27] 27. Vaknin, D., M.S. Kelley, and B.M. Ocko, Sphingomyelin at
the air--water interface. The Journal of Chemical Physics, 2001.
115(16): p. 7697-7704.
[28] Matti, V., et al., Characterization of Mixed Monolayers of
Phosphatidylcholine and a Dicationic Gemini Surfactant SS-1 with a
Langmuir Balance: Effects Of DNA. Biophysical Journal, 2001. 81(4):
p. 2135-2143.
[29] Hong, S., et al., Interaction of Polycationic Polymers with Supported
Lipid Bilayers and Cells: Nanoscale Hole Formation and Enhanced Membrane Permeability. Bioconjugate Chemistry, 2006. 17(3): p. 728-
734.
[30] Mecke, A., et al., Lipid Bilayer Disruption by Polycationic Polymers:
The Roles of Size and Chemical Functional Group. Langmuir, 2005.
21(23): p. 10348-10354.
[31] Reimhult, E., F. Höök, and B. Kasemo, Intact Vesicle Adsorption and
Supported Biomembrane Formation from Vesicles in Solution: Influence
of Surface Chemistry, Vesicle Size, Temperature, and Osmotic
Pressure†. Langmuir, 2002. 19(5): p. 1681-1691.
[1] Nel, A., et al., Toxic Potential of Materials at the Nanolevel. Science,
2006. 311(5761): p. 622-627.
[2] Leroueil, P.R., et al., Wide Varieties of Cationic Nanoparticles Induce
Defects in Supported Lipid Bilayers. Nano Letters, 2008. 8(2): p. 420-
424.
[3] Jose Ruben, M., et al., The bactericidal effect of silver nanoparticles.
Nanotechnology, 2005. 16(10): p. 2346.
[4] Roiter, Y., et al., Interaction of Nanoparticles with Lipid Membrane.
Nano Letters, 2008. 8(3): p. 941-944.
[5] Li, Y., X. Chen, and N. Gu, Computational Investigation of Interaction
between Nanoparticles and Membranes: Hydrophobic/Hydrophilic
Effect. The Journal of Physical Chemistry B, 2008. 112(51): p. 16647-
16653.
[6] Arvizo, R.R., et al., Effect of Nanoparticle Surface Charge at the
Plasma Membrane and Beyond. Nano Letters, 2010. 10(7): p. 2543-
2548.
[7] Limbach, L.K., et al., Oxide Nanoparticle Uptake in Human Lung
Fibroblasts: Effects of Particle Size, Agglomeration, and Diffusion at
Low Concentrations. Environmental Science & Technology, 2005.
39(23): p. 9370-9376.
[8] Pujalté, I., et al., Cytotoxicity and oxidative stress induced by different
metallic nanoparticles on human kidney cells. Particle and Fibre
Toxicology, 2011. 8(1): p. 1-16.
[9] Coccini, T., et al., Apoptosis induction and histological changes in rat
kidney following Cd-doped silica nanoparticle exposure: evidence of
persisting effects. Toxicology Mechanisms and Methods, 2013: p. 1-27.
[10] Yong, K.-T., et al., Nanotoxicity assessment of quantum dots: from
cellular to primate studies. Chemical Society Reviews, 2013. 42(3): p.
1236-1250.
[11] Sonnino, S. and A. Prinetti, Membrane Domains and the Lipid Raft
Concept. Current Medicinal Chemistry, 2013. 20(1): p. 4-21.
[12] Li, M., et al., AFM Studies of Solid-Supported Lipid Bilayers Formed at
a Au(111) Electrode Surface Using Vesicle Fusion and a Combination
of Langmuir−Blodgett and Langmuir−Schaefer Techniques. Langmuir,
2008. 24(18): p. 10313-10323.
[13] Giocondi, M.-C., et al., Remodeling of Ordered Membrane Domains by
GPI-Anchored Intestinal Alkaline Phosphatase. Langmuir, 2007.
23(18): p. 9358-9364.
[14] Richter, R.P., R. Bérat, and A.R. Brisson, Formation of Solid-Supported
Lipid Bilayers: An Integrated View. Langmuir, 2006. 22(8): p. 3497-
3505.
[15] Faye, N.R., et al., Oxidation of Langmuir–Blodgett films of
monounsaturated lipids studied by atomic force microscopy.
International Journal of Nanotechnology, 2013. 10(5): p. 390-403.
[16] Morandat, S., et al., Atomic force microscopy of model lipid membranes.
Analytical and Bioanalytical Chemistry, 2013. 405(5): p. 1445-1461.
[17] El Kirat, K., S. Morandat, and Y.F. Dufrêne, Nanoscale analysis of
supported lipid bilayers using atomic force microscopy. Biochimica et
Biophysica Acta (BBA) - Biomembranes, 2010. 1798(4): p. 750-765.
[18] Mingeot-Leclercq, M.-P., et al., Atomic force microscopy of supported
lipid bilayers. Nat. Protocols, 2008. 3(10): p. 1654-1659.
[19] Bouhacina, T., et al., Oscillation of the cantilever in atomic force
microscopy: Probing the sample response at the microsecond scale.
Journal of Applied Physics, 1997. 82(8): p. 3652-3660.
[20] Gauthier, S., et al., Study of Grafted Silane Molecules on Silica Surface
with an Atomic Force Microscope. Langmuir, 1996. 12(21): p. 5126-
5137.
[21] Bouhacina, T., B. Desbat, and J.P. Aimé, FTIR spectroscopy and
nanotribological comparative studies: influence of the adsorbed water
layers on the tribological behaviour. Tribology Letters, 2000. 9(1-2): p.
111-117.
[22] Kopp-Marsaudon, S., et al., Quantitative Measurement of the
Mechanical Contribution to Tapping-Mode Atomic Force Microscopy
Images of Soft Materials. Langmuir, 2000. 16(22): p. 8432-8437.
[23] Parthasarathy, R., C.-h. Yu, and J.T. Groves, Curvature-Modulated
Phase Separation in Lipid Bilayer Membranes. Langmuir, 2006. 22(11):
p. 5095-5099.
[24] Holopainen, J.M., et al., Interfacial Interactions of Ceramide with
Dimyristoylphosphatidylcholine: Impact of the N-Acyl Chain.
Biophysical Journal, 2001. 80(2): p. 765-775.
[25] Grauby-Heywang, C. and J.-M. Turlet, Behavior of GM3 ganglioside in
lipid monolayers mimicking rafts or fluid phase in membranes.
Chemistry and Physics of Lipids, 2006. 139(1): p. 68-76.
[26] Azouzi, S., K. El Kirat, and S. Morandat, The Potent Antimalarial Drug
Cyclosporin A Preferentially Destabilizes Sphingomyelin-Rich
Membranes. Langmuir, 2009. 26(3): p. 1960-1965.
[27] 27. Vaknin, D., M.S. Kelley, and B.M. Ocko, Sphingomyelin at
the air--water interface. The Journal of Chemical Physics, 2001.
115(16): p. 7697-7704.
[28] Matti, V., et al., Characterization of Mixed Monolayers of
Phosphatidylcholine and a Dicationic Gemini Surfactant SS-1 with a
Langmuir Balance: Effects Of DNA. Biophysical Journal, 2001. 81(4):
p. 2135-2143.
[29] Hong, S., et al., Interaction of Polycationic Polymers with Supported
Lipid Bilayers and Cells: Nanoscale Hole Formation and Enhanced Membrane Permeability. Bioconjugate Chemistry, 2006. 17(3): p. 728-
734.
[30] Mecke, A., et al., Lipid Bilayer Disruption by Polycationic Polymers:
The Roles of Size and Chemical Functional Group. Langmuir, 2005.
21(23): p. 10348-10354.
[31] Reimhult, E., F. Höök, and B. Kasemo, Intact Vesicle Adsorption and
Supported Biomembrane Formation from Vesicles in Solution: Influence
of Surface Chemistry, Vesicle Size, Temperature, and Osmotic
Pressure†. Langmuir, 2002. 19(5): p. 1681-1691.
@article{"International Journal of Biological, Life and Agricultural Sciences:51662", author = "Ndeye Rokhaya Faye and Ibtissem Gammoudi and Fabien Moroté and Christine Grauby-Heywang and TouriaCohen-Bouhacina", title = "Phase Behavior and Structure Properties of Supported Lipid Monolayers and Bilayers in Interaction with Silica Nanoparticles", abstract = "In this study we investigate silica nanoparticle (SiO2- NP) effects on the structure and phase properties of supported lipid monolayers and bilayers, coupling surface pressure measurements, fluorescence microscopy and atomic force microscopy. SiO2-NPs typically in size range of 10nm to 100 nm in diameter are tested. Our results suggest first that lipid molecules organization depends to their nature. Secondly, lipid molecules in the vinicity of big aggregates nanoparticles organize in liquid condensed phase whereas small aggregates are localized in both fluid liquid-expanded (LE) and liquid-condenced (LC). We demonstrated also by atomic force microscopy that by measuring friction forces it is possible to get information as if nanoparticle aggregates are recovered or not by lipid monolayers and bilayers.
", keywords = "Atomic force microscopy, fluorescence microscopy, Langmuir films, silica nanoparticles, supported membrane models.", volume = "7", number = "6", pages = "368-8", }
