Abstract: Transcription factors are a group of proteins that
helps for interpreting the genetic information in DNA.
Protein-protein interactions play a major role in the execution
of key biological functions of a cell. These interactions are
represented in the form of a graph with nodes and edges.
Studies have showed that some nodes have high degree of
connectivity and such nodes, known as hub nodes, are the
inevitable parts of the network. In the present paper a method
is proposed to identify hub transcription factor proteins using
sequence information. On a complete data set of transcription
factor proteins available from the APID database, the
proposed method showed an accuracy of 77%, sensitivity of
79% and specificity of 76%.
Abstract: Cenozoic basalts found in Jiangsu province of eastern
China include tholeiites and alkali basalts. The present paper analyzed
the major, trace elements, rare earth elements of these Cenozoic
basalts and combined with Sr-Nd isotopic compositions proposed by
Chen et al. (1990)[1] in the literatures to discuss the petrogenesis of
these basalts and the geochemical characteristics of the source mantle.
Based on major, trace elements and fractional crystallization model
established by Brooks and Nielsen (1982)[2] we suggest that the
basaltic magma has experienced olivine + clinopyroxene fractionation
during its evolution. The chemical compositions of basaltic rocks from
Jiangsu province indicate that these basalts may belong to the same
magmatic system. Spidergrams reveal that Cenozoic basalts from
Jiangsu province have geochemical characteristics similar to those of
ocean island basalts(OIB). The slight positive Nb and Ti anomalies
found in basaltic rocks of this study suggest the presence of Ti-bearing
minerals in the mantle source and these Ti-bearing minerals had
contributed to basaltic magma during partial melting, indicating a
metasomatic event might have occurred before the partial melting.
Based on the Sr vs. Nd isotopic ratio plots, we suggest that Jiangsu
basalts may be derived from partial melting of mantle source which
may represent two-end members mixing of DMM and EM-I. Some
Jiangsu basaltic magma may be derived from partial melting of EM-I
heated by the upwelling asthenospheric mantle or asthenospheric
diapirism.
Abstract: The three-time-scale plant model of a wind power
generator, including a wind turbine, a flexible vertical shaft, a Variable
Inertia Flywheel (VIF) module, an Active Magnetic Bearing (AMB)
unit and the applied wind sequence, is constructed. In order to make
the wind power generator be still able to operate as the spindle speed
exceeds its rated speed, the VIF is equipped so that the spindle speed
can be appropriately slowed down once any stronger wind field is
exerted. To prevent any potential damage due to collision by shaft
against conventional bearings, the AMB unit is proposed to regulate
the shaft position deviation. By singular perturbation order-reduction
technique, a lower-order plant model can be established for the
synthesis of feedback controller. Two major system parameter
uncertainties, an additive uncertainty and a multiplicative uncertainty,
are constituted by the wind turbine and the VIF respectively.
Frequency Shaping Sliding Mode Control (FSSMC) loop is proposed
to account for these uncertainties and suppress the unmodeled
higher-order plant dynamics. At last, the efficacy of the FSSMC is
verified by intensive computer and experimental simulations for
regulation on position deviation of the shaft and counter-balance of
unpredictable wind disturbance.
Abstract: Twist drills are geometrical complex tools and thus various researchers have adopted different mathematical and experimental approaches for their simulation. The present paper acknowledges the increasing use of modern CAD systems and using the API (Application Programming Interface) of a CAD system, drilling simulations are carried out. The developed DRILL3D software routine, creates parametrically controlled tool geometries and using different cutting conditions, achieves the generation of solid models for all the relevant data involved (drilling tool, cut workpiece, undeformed chip). The final data derived, consist a platform for further direct simulations regarding the determination of cutting forces, tool wear, drilling optimizations etc.
Abstract: Microcirculation is essential for the proper supply of
oxygen and nutritive substances to the biological tissue and the
removal of waste products of metabolism. The determination of
blood flow in the capillaries is therefore of great interest to clinicians.
A comparison has been carried out using the developed non-invasive,
non-contact and whole field laser speckle contrast imaging (LSCI)
based technique and as well as a commercially available laser
Doppler blood flowmeter (LDF) to evaluate blood flow at the finger
tip and elbow and is presented here. The LSCI technique gives more
quantitative information on the velocity of blood when compared to
the perfusion values obtained using the LDF. Measurement of blood
flow in capillaries can be of great interest to clinicians in the
diagnosis of vascular diseases of the upper extremities.
Abstract: In this work we adopt a combination of Laplace
transform and the decomposition method to find numerical solutions
of a system of multi-pantograph equations. The procedure leads to a
rapid convergence of the series to the exact solution after computing a
few terms. The effectiveness of the method is demonstrated in some
examples by obtaining the exact solution and in others by computing
the absolute error which decreases as the number of terms of the series
increases.
Abstract: This study examines the impact of working capital
management on firms- performance and market value of the firms in
Nigeria. A sample of fifty four non-financial quoted firms in Nigeria
listed on the Nigeria Stock Exchange was used for this study. Data
were collected from annual reports of the sampled firms for the
period 1995-2009. This result shows there is a significant negative
relationship between cash conversion cycle and market valuation
and firm-s performance. It also shows that debt ratio is positively
related to market valuation and negatively related firm-s
performance. The findings confirm that there is a significant
relationship between Market valuation, profitability and working
capital component in line with previous studies. This mean that
Nigeria firms should ensure adequate management of working
capital especially cash conversion cycle components of account
receivables, account payables and inventories, as efficiency working
capital management is expected to contribute positively to the firms-
market value.
Abstract: Communication is becoming a significant tool to engage stakeholders since half of the century ago. In the recent years, there has been rapid growth of new technology developments. In tandem with such developments, there has been growing emphasis in communication strategies and management especially in determining the level of influence and management strategies among the said stakeholders on particular field. This paper presents a research conceptual framework focusing on stakeholder theories, communication and management strategies to be implied on the engagement of stakeholders of new technology developments of fertilizer industry in Malaysia. Framework espoused in this paper will provide insights into the various stakeholder theories and engagement strategies from different principal necessary for a successful introduction of new technology development in the above stated industry. The proposed framework has theoretical significance in filling the gap of the body of knowledge in the implementation of communication strategies in Malaysian fertilizer industry.
Abstract: Knowledge is attributed to human whose problemsolving
behavior is subjective and complex. In today-s knowledge
economy, the need to manage knowledge produced by a community
of actors cannot be overemphasized. This is due to the fact that
actors possess some level of tacit knowledge which is generally
difficult to articulate. Problem-solving requires searching and sharing
of knowledge among a group of actors in a particular context.
Knowledge expressed within the context of a problem resolution
must be capitalized for future reuse. In this paper, an approach that
permits dynamic capitalization of relevant and reliable actors-
knowledge in solving decision problem following Economic
Intelligence process is proposed. Knowledge annotation method and
temporal attributes are used for handling the complexity in the
communication among actors and in contextualizing expressed
knowledge. A prototype is built to demonstrate the functionalities of
a collaborative Knowledge Management system based on this
approach. It is tested with sample cases and the result showed that
dynamic capitalization leads to knowledge validation hence
increasing reliability of captured knowledge for reuse. The system
can be adapted to various domains.
Abstract: Saudi Arabia in recent years has seen drastic increase
in traffic related crashes. With population of over 29 million, Saudi
Arabia is considered as a fast growing and emerging economy. The
rapid population increase and economic growth has resulted in rapid
expansion of transportation infrastructure, which has led to increase
in road crashes. Saudi Ministry of Interior reported more than 7,000
people killed and 68,000 injured in 2011 ranking Saudi Arabia to be
one of the worst worldwide in traffic safety. The traffic safety issues
in the country also result in distress to road users and cause and
economic loss exceeding 3.7 billion Euros annually. Keeping this in
view, the researchers in Saudi Arabia are investigating ways to
improve traffic safety conditions in the country. This paper presents a
multilevel approach to collect traffic safety related data required to do
traffic safety studies in the region. Two highway corridors including
King Fahd Highway 39 kilometre and Gulf Cooperation Council
Highway 42 kilometre long connecting the cities of Dammam and
Khobar were selected as a study area. Traffic data collected included
traffic counts, crash data, travel time data, and speed data. The
collected data was analysed using geographic information system to
evaluate any correlation. Further research is needed to investigate the
effectiveness of traffic safety related data when collected in a
concerted effort.
Abstract: Several models of vulnerability assessment have been proposed. The selection of one of these models depends on the objectives of the study. The classical methodologies for seismic vulnerability analysis, as a part of seismic risk analysis, have been formulated with statistical criteria based on a rapid observation. The information relating to the buildings performance is statistically elaborated. In this paper, we use the European Macroseismic Scale EMS-98 to define the relationship between damage and macroseismic intensity to assess the seismic vulnerability. Applying to Algiers area, the first step is to identify building typologies and to assign vulnerability classes. In the second step, damages are investigated according to EMS-98.
Abstract: Modern managements of water distribution system
(WDS) need water quality models that are able to accurately predict
the dynamics of water quality variations within the distribution system
environment. Before water quality models can be applied to solve
system problems, they should be calibrated. Although former
researchers use GA solver to calibrate relative parameters, it is
difficult to apply on the large-scale or medium-scale real system for
long computational time. In this paper a new method is designed
which combines both macro and detailed model to optimize the water
quality parameters. This new combinational algorithm uses radial
basis function (RBF) metamodeling as a surrogate to be optimized for
the purpose of decreasing the times of time-consuming water quality
simulation and can realize rapidly the calibration of pipe wall reaction
coefficients of chlorine model of large-scaled WDS. After two cases
study this method is testified to be more efficient and promising, and
deserve to generalize in the future.
Abstract: The paper proposes a new concept in developing
collaborative design system. The concept framework involves
applying simulation of supply chain management to collaborative
design called – 'SCM–Based Design Tool'. The system is developed
particularly to support design activities and to integrate all facilities
together. The system is aimed to increase design productivity and
creativity. Therefore, designers and customers can collaborate by the
system since conceptual design. JAG: Jewelry Art Generator based
on artificial intelligence techniques is integrated into the system.
Moreover, the proposed system can support users as decision tool
and data propagation. The system covers since raw material supply
until product delivery. Data management and sharing information are
visually supported to designers and customers via user interface. The
system is developed on Web–assisted product development
environment. The prototype system is presented for Thai jewelry
industry as a system prototype demonstration, but applicable for
other industry.
Abstract: In this competitive age, one of the key tools of most successful organizations is knowledge management. Today some organizations measure their current knowledge and use it as an indicator for rating the organization on their reports. Noting that the universities and colleges of medical science have a great role in public health of societies, their access to newest scientific research and the establishment of organizational knowledge management systems is very important. In order to explore the Application of Knowledge Management Factors, a national study was undertaken. The main purpose of this study was to find the rate of the application of knowledge management factors and some ways to establish more application of knowledge management system in Esfahan University-s Medical College (EUMC). Esfahan is the second largest city after Tehran, the capital city of Iran, and the EUMC is the biggest medical college in Esfahan. To rate the application of knowledge management, this study uses a quantitative research methodology based on Probst, Raub and Romhardt model of knowledge management. A group of 267 faculty members and staff of the EUMC were asked via questionnaire. Finding showed that the rate of the application of knowledge management factors in EUMC have been lower than average. As a result, an interview with ten faculty members conducted to find the guidelines to establish more applications of knowledge management system in EUMC.
Abstract: In this paper, we discuss the paradigm shift in bank
capital from the “gone concern" to the “going concern" mindset. We
then propose a methodology for pricing a product of this shift called
Contingent Capital Notes (“CoCos"). The Merton Model can
determine a price for credit risk by using the firm-s equity value as a
call option on those assets. Our pricing methodology for CoCos also
uses the credit spread implied by the Merton Model in a subsequent
derivative form created by John Hull et al . Here, a market implied
asset volatility is calculated by using observed market CDS spreads.
This implied asset volatility is then used to estimate the probability of
triggering a predetermined “contingency event" given the distanceto-
trigger (DTT). The paper then investigates the effect of varying
DTTs and recovery assumptions on the CoCo yield. We conclude
with an investment rationale.
Abstract: In this cyber age, the job market has been rapidly transforming and being digitalized. Submitting a paper-based curriculum vitae (CV) nowadays does not grant a job seeker a high employability rate. This paper calls for attention on the creation of mobile Curriculum Vitae or m-CV (http://mcurriculumvitae. blogspot.com), a sample of an individual CV developed using weblog, which can enhance the job hunter especially fresh graduate-s higher marketability rate. This study is designed to identify the perceptions held by Malaysian university students regarding m-CV grounded on a modified Technology Acceptance Model (TAM). It measures the strength and the direction of relationships among three major variables – Perceived Ease of Use (PEOU), Perceived Usefulness (PU) and Behavioral Intention (BI) to use. The finding shows that university students generally accepted adopting m-CV since they perceived m-CV to be more useful rather than easy to use. Additionally, this study has confirmed TAM to be a useful theoretical model in helping to understand and explain the behavioral intention to use Web 2.0 application-weblog publishing their CV. The result of the study has underlined another significant positive value of using weblog to create personal CV. Further research of m-CV has been highlighted in this paper.
Abstract: Injection molding is a very complicated process to
monitor and control. With its high complexity and many process
parameters, the optimization of these systems is a very challenging
problem. To meet the requirements and costs demanded by the
market, there has been an intense development and research with the
aim to maintain the process under control. This paper outlines the
latest advances in necessary algorithms for plastic injection process
and monitoring, and also a flexible data acquisition system that
allows rapid implementation of complex algorithms to assess their
correct performance and can be integrated in the quality control
process. This is the main topic of this paper. Finally, to demonstrate
the performance achieved by this combination, a real case of use is
presented.
Abstract: The Mobile Ad-hoc Network (MANET) is a collection of self-configuring and rapidly deployed mobile nodes (routers) without any central infrastructure. Routing is one of the potential issues. Many routing protocols are reported but it is difficult to decide which one is best in all scenarios. In this paper on demand routing protocols DSR and DYMO based on IEEE 802.11 DCF MAC protocol are examined and characteristic summary of these routing protocols is presented. Their performance is analyzed and compared on performance measuring metrics throughput, dropped packets due to non availability of routes, duplicate RREQ generated for route discovery and normalized routing load by varying CBR data traffic load using QualNet 5.0.2 network simulator.
Abstract: The hydrogen peroxide treatment was able to
remediate chlorophenols, polycyclic aromatic hydrocarbons, diesel
and transformer oil contaminated soil. Chemical treatment of
contaminants adsorbed in peat resulted in lower contaminants-
removal and required higher addition of chemicals than the treatment
of contaminants in sand. The hydrogen peroxide treatment was found
to be feasible for soil remediation at natural soil pH. Contaminants in
soil could degrade with the addition of hydrogen peroxide only
indicating the ability of transition metals ions and minerals of these
metals presented in soil to catalyse the reaction of hydrogen peroxide
decomposition.
Abstract: The concurrent era is characterised by strengthened interactions among financial markets and increased capital mobility globally. In this frames we examine the effects the international financial integration process has on the European bond markets. We perform a comparative study of the interactions of the European and international bond markets and exploit Cointegration analysis results on the elimination of stochastic trends and the decomposition of the underlying long run equilibria and short run causal relations. Our investigation provides evidence on the relation between the European integration process and that of globalisation, viewed through the bond markets- sector. Additionally the structural formulation applied, offers significant implications of the findings. All in all our analysis offers a number of answers on crucial queries towards the European bond markets integration process.