Abstract: Transcription factor p53 has a powerful tumor
suppressing function that is associated with many cancers. However,
p53 of the molecular weight was higher make the limitation across to
skin or cell membrane. Thymidine dinucleotide (pTT), an
oligonucleotide, can activate the p53 transcription factor. pTT is a
hydrophilic and negative charge oligonucleotide, which delivery in to
cell membrane need an appropriate carrier. The aim of this study was
to improve the bioavailability of the nucleotide fragment, thymidine
dinucleotide (pTT), using elasic liposome carriers to deliver the drug
into the skin. The study demonstrate that dioleoylphosphocholine
(DOPC) incorporated with sodium cholate at molar ratio 1:1 can
archived the particle size about 220 nm. This elastic liposome could
penetration through skin from stratum corneum to whole epidermis by
confocal laser scanning microscopy (CLSM). Moreover, we observed
the the slight increase in generation of p53 by western blot.
Abstract: In this paper, we have focused on study of swelling kinetics and salt-sensitivity behavior of a superabsorbing hydrogel based on carboxymethylcellulose (CMC) and acrylic acid and 2- Buthyl methacrylate. The swelling kinetics of the hydrogels with various particle sizes was preliminary investigated as well. The swelling of the hydrogel showed a second order kinetics of swelling in water. In addition, swelling measurements of the synthesized hydrogels in various chloride salt solutions was measured. Results indicated that a swelling-loss with an increase in the ionic strength of the salt solutions.
Abstract: Recently, various services such as television and the
Internet have come to be received through various terminals.
However, we could gain greater convenience by receiving these
services through cellular phone terminals when we go out and then
continuing to receive the same services through a large screen digital
television after we have come home. However, it is necessary to go
through the same authentication processing again when using TVs
after we have come home. In this study, we have developed an
authentication method that enables users to switch terminals in
environments in which the user receives service from a server through
a terminal. Specifically, the method simplifies the authentication of
the server side when switching from one terminal to another terminal
by using previously authenticated information.
Abstract: The competitive learning is an adaptive process in
which the neurons in a neural network gradually become sensitive to
different input pattern clusters. The basic idea behind the Kohonen-s
Self-Organizing Feature Maps (SOFM) is competitive learning.
SOFM can generate mappings from high-dimensional signal spaces
to lower dimensional topological structures. The main features of this
kind of mappings are topology preserving, feature mappings and
probability distribution approximation of input patterns. To overcome
some limitations of SOFM, e.g., a fixed number of neural units and a
topology of fixed dimensionality, Growing Self-Organizing Neural
Network (GSONN) can be used. GSONN can change its topological
structure during learning. It grows by learning and shrinks by
forgetting. To speed up the training and convergence, a new variant
of GSONN, twin growing cell structures (TGCS) is presented here.
This paper first gives an introduction to competitive learning, SOFM
and its variants. Then, we discuss some GSONN with fixed
dimensionality, which include growing cell structures, its variants
and the author-s model: TGCS. It is ended with some testing results
comparison and conclusions.
Abstract: Image enhancement is the most important challenging preprocessing for almost all applications of Image Processing. By now, various methods such as Median filter, α-trimmed mean filter, etc. have been suggested. It was proved that the α-trimmed mean filter is the modification of median and mean filters. On the other hand, ε-filters have shown excellent performance in suppressing noise. In spite of their simplicity, they achieve good results. However, conventional ε-filter is based on moving average. In this paper, we suggested a new ε-filter which utilizes α-trimmed mean. We argue that this new method gives better outcomes compared to previous ones and the experimental results confirmed this claim.
Abstract: Several trillion cigarettes produced worldwide annually lead to many thousands of kilograms of toxic waste. Cigarette butts (CBs) accumulate in the environment due to the poor biodegradability of the cellulose acetate filters. This paper presents some of the results from a continuing study on recycling CBs into fired clay bricks. Physico-mechanical properties of fired clay bricks manufactured with different percentages of CBs are reported and discussed. The results show that the density of fired bricks was reduced by up to 30 %, depending on the percentage of CBs incorporated into the raw materials. Similarly, the compressive strength of bricks tested decreased according to the percentage of CBs included in the mix. The thermal conductivity performance of bricks was improved by 51 and 58 % for 5 and 10 % CBs content respectively. Leaching tests were carried out to investigate the levels of possible leachates of heavy metals from the manufactured clay-CB bricks. The results revealed trace amounts of heavy metals.
Abstract: Cognitive models allow predicting some aspects of utility
and usability of human machine interfaces (HMI), and simulating
the interaction with these interfaces. The action of predicting is based
on a task analysis, which investigates what a user is required to do
in terms of actions and cognitive processes to achieve a task. Task
analysis facilitates the understanding of the system-s functionalities.
Cognitive models are part of the analytical approaches, that do not
associate the users during the development process of the interface.
This article presents a study about the evaluation of a human
machine interaction with a contextual assistant-s interface using ACTR
and GOMS cognitive models. The present work shows how these
techniques may be applied in the evaluation of HMI, design and
research by emphasizing firstly the task analysis and secondly the
time execution of the task. In order to validate and support our
results, an experimental study of user performance is conducted at
the DOMUS laboratory, during the interaction with the contextual
assistant-s interface. The results of our models show that the GOMS
and ACT-R models give good and excellent predictions respectively
of users performance at the task level, as well as the object level.
Therefore, the simulated results are very close to the results obtained
in the experimental study.
Abstract: This study investigates the electrical performance of a
planar solid oxide fuel cell unit with cross-flow configuration when the fuel utilization gets higher and the fuel inlet flow are non-uniform.
A software package in this study solves two-dimensional,
simultaneous, partial differential equations of mass, energy, and
electro-chemistry, without considering stack direction variation. The
results show that the fuel utilization increases with a decrease in the molar flow rate, and the average current density decreases when the
molar flow rate drops. In addition, non-uniform Pattern A will induce more severe happening of non-reaction area in the corner of the fuel
exit and the air inlet. This non-reaction area deteriorates the average
current density and then deteriorates the electrical performance to –7%.
Abstract: A challenging problem in radar signal processing is to
achieve reliable target detection in the presence of interferences. In
this paper, we propose a novel algorithm for automatic censoring of
radar interfering targets in log-normal clutter. The proposed
algorithm, termed the forward automatic censored cell averaging
detector (F-ACCAD), consists of two steps: removing the corrupted
reference cells (censoring) and the actual detection. Both steps are
performed dynamically by using a suitable set of ranked cells to
estimate the unknown background level and set the adaptive
thresholds accordingly. The F-ACCAD algorithm does not require
any prior information about the clutter parameters nor does it require
the number of interfering targets. The effectiveness of the F-ACCAD
algorithm is assessed by computing, using Monte Carlo simulations,
the probability of censoring and the probability of detection in
different background environments.
Abstract: The aim of the study was to evaluate the effect of
texturizers on the rheological properties of the apple mass and
desserts made from various raw materials. The apple varieties -
‘Antonovka’, ‘Baltais Dzidrais’, and ‘Zarja Alatau’ harvested in
Latvia, were used for the experiment. The apples were processed in a
blender unpeeled for obtaining a homogenous mass. The apple mass
was analyzed fresh and after storage at –18ºC. Both fresh and thawed
apple mass samples with added gelatin, xantan gum, and sodium
carboxymethylcellulose were whisked obtaining dessert. Pectin, pH
and soluble dry matter of the product were determined. Apparent
viscosity was measured using a rotational viscometer DV–III Ultra.
Pectin content in frozen apple mass decreased significantly (p
Abstract: Querying a data source and routing data towards sink
becomes a serious challenge in static wireless sensor networks if sink
and/or data source are mobile. Many a times the event to be observed
either moves or spreads across wide area making maintenance of
continuous path between source and sink a challenge. Also, sink can
move while query is being issued or data is on its way towards sink.
In this paper, we extend our already proposed Grid Based Data
Dissemination (GBDD) scheme which is a virtual grid based
topology management scheme restricting impact of movement of
sink(s) and event(s) to some specific cells of a grid. This obviates the
need for frequent path modifications and hence maintains continuous
flow of data while minimizing the network energy consumptions.
Simulation experiments show significant improvements in network
energy savings and average packet delay for a packet to reach at sink.
Abstract: Object-oriented programming is a wonderful way to
make programming of huge real life tasks much easier than by using
procedural languages. In order to teach those ideas to students, it
is important to find a good task that shows the advantages of OOprogramming
very naturally. This paper gives an example, the game
Battleship, which seems to work excellent for teaching the OO ideas
(using Java, [1], [2], [3], [4]).
A three-step task is presented for how to teach OO-programming
using just one example suitable to convey many of the OO ideas.
Observations are given at the end and conclusions about how the
whole teaching course worked out.
Abstract: Cell phone forensics to acquire and analyze data in the
cellular phone is nowadays being used in a national investigation
organization and a private company. In order to collect cellular phone
flash memory data, we have two methods. Firstly, it is a logical
method which acquires files and directories from the file system of the
cell phone flash memory. Secondly, we can get all data from bit-by-bit
copy of entire physical memory using a low level access method. In
this paper, we describe a forensic tool to acquire cell phone flash
memory data using a logical level approach. By our tool, we can get
EFS file system and peek memory data with an arbitrary region from
Korea CDMA cell phone.
Abstract: A new conserving approach in the context of Immersed Boundary Method (IBM) is presented to simulate one dimensional, incompressible flow in a moving boundary problem. The method employs control volume scheme to simulate the flow field. The concept of ghost node is used at the boundaries to conserve the mass and momentum equations. The Present method implements the conservation laws in all cells including boundary control volumes. Application of the method is studied in a test case with moving boundary. Comparison between the results of this new method and a sharp interface (Image Point Method) IBM algorithm shows a well distinguished improvement in both pressure and velocity fields of the present method. Fluctuations in pressure field are fully resolved in this proposed method. This approach expands the IBM capability to simulate flow field for variety of problems by implementing conservation laws in a fully Cartesian grid compared to other conserving methods.
Abstract: This paper investigates the application of large scale (LS-PV) two-axis tracking photovoltaic power plant in Al-Jagbob, Libya. A 50MW PV-grid connected (two-axis tracking) power plant design in Al-Jagbob, Libya has been carried out presently. A hetero-junction with intrinsic thin layer (HIT) type PV module has been selected and modeled. A Microsoft Excel-VBA program has been constructed to compute slope radiation, dew-point, sky temperature, and then cell temperature, maximum power output and module efficiency for this system, for tracking system. The results for energy production show that the total energy output is 128.5 GWh/year. The average module efficiency is 16.6%. The electricity generation capacity factor (CF) and solar capacity factor (SCF) were found to be 29.3% and 70.4% respectively. A 50MW two axis tracking power plant with a total energy output of 128.5 GWh/year would reduce CO2 pollution by 85,581 tonnes of each year. The payback time for the proposed LS-PV photovoltaic power plant was found to be 4 years.
Abstract: Antimosy-doped tin oxide (ATO) particles were
prepared via chemical coprecipitation and reverse emulsion. The size
and size distribution of ATO particles were obviously decreased via
reverse microemulsion method. At the relatively high yield the ATO
particles were nearly spherical in shape, meanwhile the crystalline
structure and excellent conductivity were reserved, which could satisfy
the requirement as composite fillers, such as dielectric filler of
polyimide film.
Abstract: Mechanical interaction between endothelial cells (ECs) and the extracellular matrix (or collagen gel) is known to influence the sprouting response of endothelial cells during angiogenesis. This influence is believed to impact on the capability of endothelial cells to sense soluble chemical cues. Quantitative analysis of endothelial-cell-mediated displacement of the collagen gel provides a means to explore this mechanical interaction. Existing analysis in this context is generally limited to 2D settings. In this paper, we investigate the mechanical interaction between endothelial cells and the extracellular matrix in terms of the endothelial-cellmediated displacement of the collagen gel in both 2D and 3D. Digital image correlation and Digital volume correlation are applied on confocal reflectance image stacks to analyze cell-mediated displacement of the gel. The skeleton of the sprout is extracted from phase contrast images and superimposed on the displacement field to further investigate the link between the development of the sprout and the displacement of the gel.
Abstract: Topical photodynamic therapy (PDT) with
5-aminolevulinic acid (ALA) is an alternative therapy for treating
superficial cancer, especially for skin or oral cancer. ALA, a precursor
of the photosensitizer protoporphyrin IX (PpIX), is present as
zwitterions and hydrophilic property which make the low permeability
through the cell membrane. Collagen is a traditional carrier; its
molecular composed various amino acids which bear positive charge
and negative charge. In order to utilize the ion-pairs with ALA and
collagen, the study employed various pH values adjusting the net
charge. The aim of this study was to compare a series collagen form,
including solution, gel and sponge to investigate the topical delivery
behavior of ALA. The in vivo confocal laser scanning microscopy
(CLSM) study demonstrated that PpIX generation ability was different
pattern after apply for 6 h. Gel type could generate high PpIX, and
archived more deep of skin depth.
Abstract: In the present simulation work, an attempt is made to study the switching dynamics of an optically controlled 4HSiC thyristor power semiconductor device with the use of GaAs optically triggered power transistor. The half-cell thyristor has the forward breakdown of 200 V and reverse breakdown of more than 1000 V. The optically controlled thyristor has a rise time of 0.14 μs and fall time of 0.065 μs. The turn-on and turn-off delays are 0.1 μs and 0.06 μs, respectively. In addition, this optically controlled thyristor is used as a control switch for the DC-DC Boost converter. The pn-diode used for the converter has the forward drop of 2.8 V and reverse breakdown of around 400 V.
Abstract: Human activity is a major concern in a wide variety of
applications, such as video surveillance, human computer interface
and face image database management. Detecting and recognizing
faces is a crucial step in these applications. Furthermore, major
advancements and initiatives in security applications in the past years
have propelled face recognition technology into the spotlight. The
performance of existing face recognition systems declines significantly
if the resolution of the face image falls below a certain level.
This is especially critical in surveillance imagery where often, due to
many reasons, only low-resolution video of faces is available. If these
low-resolution images are passed to a face recognition system, the
performance is usually unacceptable. Hence, resolution plays a key
role in face recognition systems. In this paper we introduce a new
low resolution face recognition system based on mixture of expert
neural networks. In order to produce the low resolution input images
we down-sampled the 48 × 48 ORL images to 12 × 12 ones using
the nearest neighbor interpolation method and after that applying
the bicubic interpolation method yields enhanced images which is
given to the Principal Component Analysis feature extractor system.
Comparison with some of the most related methods indicates that
the proposed novel model yields excellent recognition rate in low
resolution face recognition that is the recognition rate of 100% for
the training set and 96.5% for the test set.