Abstract: The progress of concentrations of particular heavy metals was assessed in chosen localities in region Moravia, the Czech Republic, from 2007 to 2009. Particular metals were observed in localities with various types and characterization of zone. Pb, Ni, As and Cd were emphasized as a result of their toxicity and potential adverse health effect to the exposed population. The progress of metal concentrations and their health effects in the most polluted localities were examined. According to the results, the air pollution limit values were not exceeded. Based on the health risk assessment, the probability of developing tumorous diseases is acceptable, except for the increased probability of cancer risk from long-term exposure to As.
Abstract: Sense-antisense gene pair (SAGP) is a pair of two oppositely transcribed genes sharing a common region on a chromosome. In the mammalian genomes, SAGPs can be organized in more complex sense-antisense gene architectures (CSAGA) in which at least one gene could share loci with two or more antisense partners. Many dozens of CSAGAs can be found in the human genome. However, CSAGAs have not been systematically identified and characterized in context of their role in human diseases including cancers. In this work we characterize the structural-functional properties of a cluster of 5 genes –TMEM97, IFT20, TNFAIP1, POLDIP2 and TMEM199, termed TNFAIP1 / POLDIP2 module. This cluster is organized as CSAGA in cytoband 17q11.2. Affymetrix U133A&B expression data of two large cohorts (410 atients, in total) of breast cancer patients and patient survival data were used. For the both studied cohorts, we demonstrate (i) strong and reproducible transcriptional co-regulatory patterns of genes of TNFAIP1/POLDIP2 module in breast cancer cell subtypes and (ii) significant associations of TNFAIP1/POLDIP2 CSAGA with amplification of the CSAGA region in breast cancer, (ii) cancer aggressiveness (e.g. genetic grades) and (iv) disease free patient-s survival. Moreover, gene pairs of this module demonstrate strong synergetic effect in the prognosis of time of breast cancer relapse. We suggest that TNFAIP1/ POLDIP2 cluster can be considered as a novel type of structural-functional gene modules in the human genome.
Abstract: Turbulence modeling of large-scale flow over a vegetated surface is complex. Such problems involve large scale computational domains, while the characteristics of flow near the surface are also involved. In modeling large scale flow, surface roughness including vegetation is generally taken into account by mean of roughness parameters in the modified law of the wall. However, the turbulence structure within the canopy region cannot be captured with this method, another method which applies source/sink terms to model plant drag can be used. These models have been developed and tested intensively but with a simple surface geometry. This paper aims to compare the use of roughness parameter, and additional source/sink terms in modeling the effect of plant drag on wind flow over a complex vegetated surface. The RNG k-ε turbulence model with the non-equilibrium wall function was tested with both cases. In addition, the k-ω turbulence model, which is claimed to be computationally stable, was also investigated with the source/sink terms. All numerical results were compared to the experimental results obtained at the study site Mason Bay, Stewart Island, New Zealand. In the near-surface region, it is found that the results obtained by using the source/sink term are more accurate than those using roughness parameters. The k-ω turbulence model with source/sink term is more appropriate as it is more accurate and more computationally stable than the RNG k-ε turbulence model. At higher region, there is no significant difference amongst the results obtained from all simulations.
Abstract: This paper examines the readability of the chairman’s narratives, as determined by the Flesch score, of a Malaysian public listed company’s corporate reports from 1962 to 2009. It partially supports earlier studies which demonstrated that corporate reports were difficult to read, and had shown very negligible decrease in difficulty over time. Net profit to sales and readability was significantly positively correlated but number of financial statements was significantly negatively correlated with readability.
Abstract: This paper is a simple and systematic approaches to the design and analysis a pulse width modulation (PWM) based sliding mode controller for buck DC-DC Converters. Various aspects of the design, including the practical problems and the proposed solutions, are detailed. However, these control strategies can't compensate for large load current and input voltage variations. In this paper, a new control strategy by compromising both schemes advantages and avoiding their drawbacks is proposed, analyzed and simulated.
Abstract:
Innovation is becoming more and more important in
modern society. There are a lot of researches on different kinds of
innovation but marketing innovation is one kind of innovation that
has not been studied frequently before. Marketing innovation is
defined as a new way in which companies can market themselves to
potential or existing customers.
The study shows some key elements for marketing innovation that
are worth paying attention to when implementing marketing
innovation projects. Examples of such key elements are: paying
attention to the neglected market, suitable market segmentatio
reliable market information, public relationship, increased customer
value, combination of market factors, explore different marketing
channels and the use of technology in combination with what? Beside
the key elements for marketing innovation, we also present some
risks that may occur, such as cost, market uncertainty, information
leakage, imitation and overdependence on experience.
By proposing a set of indicators to measure marketing innovation,
the article offers solutions for marketing innovation implementation
so that any organization can achieve optimal results.
Abstract: This study is aimed to investigate feasibility of the
aerobic biological process to treat oily wastewater from palm oil food
industry. Effect of aeration and sludge concentrations are studied.
Raw sludge and raw wastewater was mixed and acclimatized for five
days in a stirred tank reactor. The aeration rate (no aeration, low;
1.5L/min and high rate; 2L/min) and sludge concentration (3675,
7350, and 11025mg/L of VSS) were varied. Responses of process
were pH, COD, oil and grease, VSS, and PHB content. It was found
that the treatment can remove 85.1 to 97.1 % of COD and remove
12.9 to 54.8% of oil & grease. The PHB yield was found to be within
0.15% to 2.4% as PHB/VSS ratio and 0.01% to 0.12% as PHB/COD
removed. The higher aeration results a high COD removal and oil &
grease removal, while experiment without aeration gives better PHB
yield. Higher sludge concentrations (11025mg/L VSS) give higher
removal of oil & grease while moderate sludge concentration
(7350mg/L VSS) give better result in COD removal. Higher PHB
yield is obtained in low sludge concentration (3675mg/L).
Abstract: The paper compares different channel models used for
modeling Broadband Power-Line Communication (BPLC) system.
The models compared are Zimmermann and Dostert, Philipps,
Anatory et al and Anatory et al generalized Transmission Line (TL)
model. The validity of each model was compared in time domain
with ATP-EMTP software which uses transmission line approach. It
is found that for a power-line network with minimum number of
branches all the models give similar signal/pulse time responses
compared with ATP-EMTP software; however, Zimmermann and
Dostert model indicates the same amplitude but different time delay.
It is observed that when the numbers of branches are increased only
generalized TL theory approach results are comparable with ATPEMTP
results. Also the Multi-Carrier Spread Spectrum (MC-SS)
system was applied to check the implication of such behavior on the
modulation schemes. It is observed that using Philipps on the
underground cable can predict the performance up to 25dB better
than other channel models which can misread the actual performance
of the system. Also modified Zimmermann and Dostert under
multipath can predict a better performance of about 5dB better than
the actual predicted by Generalized TL theory. It is therefore
suggested for a realistic BPLC system design and analyses the model
based on generalized TL theory be used.
Abstract: Even it has been recognized that Shape Memory
Alloys (SMA) have a significant potential for deployment actuators,
the number of applications of SMA-based actuators to the present
day is still quite small, due to the need of deep understanding of the
thermo-mechanical behavior of SMA, causing an important need for
a mathematical model able to describe all thermo-mechanical
properties of SMA by relatively simple final set of constitutive
equations. SMAs offer attractive potentials such as: reversible strains
of several percent, generation of high recovery stresses and high
power / weight ratios. The paper tries to provide an overview of the
shape memory functions and a presentation of the designed and
developed temperature control system used for a gripper actuated by
two pairs of differential SMA active springs. An experimental setup
was established, using electrical energy for actuator-s springs heating
process. As for holding the temperature of the SMA springs at certain
level for a long time was developed a control system in order to
avoid the active elements overheating.
Abstract: Meta-reasoning is essential for multi-agent communication. In this paper we propose a framework of multi-agent communication in which agents employ meta-reasoning to reason with agent and ontology locations in order to communicate semantic information with other agents on the semantic web and also reason with multiple distributed ontologies. We shall argue that multi-agent communication of Semantic Web information cannot be realized without the need to reason with agent and ontology locations. This is because for an agent to be able to communicate with another agent, it must know where and how to send a message to that agent. Similarly, for an agent to be able to reason with an external semantic web ontology, it must know where and how to access to that ontology. The agent framework and its communication mechanism are formulated entirely in meta-logic.
Abstract: Lignocellulosic materials are considered the most
abundant renewable resource available for the Bioethanol
Production. Water Hyacinth is one of potential raw material of the
world-s worst aquatic plant as a feedstock to produce Bioethanol.
The purposed this research is obtain reduced of matter for
biodegradation lignin in Biological pretreatment with White Rot
Fungi eg. Phanerochaete Chrysosporium using Solid state
Fermentation methods. Phanerochaete Chrysosporium is known to
have the best ability to degraded lignin, but simultaneously it can also
degraded cellulose and hemicelulose. During 8 weeks incubation,
water hyacinth occurred loss of weight reached 34,67%, while loss
of lignin reached 67,21%, loss of cellulose reached 11,01% and loss
of hemicellulose reached 36,56%. The kinetic of losses lignin using
regression linear plot, the results is obtained constant rate (k) of
reduction lignin is -0.1053 and the equation of reduction of lignin
is y = wo - 0, 1.53 x
Abstract: In recent years, copulas have become very popular in
financial research and actuarial science as they are more flexible in
modelling the co-movements and relationships of risk factors as compared
to the conventional linear correlation coefficient by Pearson.
However, a precise estimation of the copula parameters is vital in
order to correctly capture the (possibly nonlinear) dependence structure
and joint tail events. In this study, we employ two optimization
heuristics, namely Differential Evolution and Threshold Accepting to
tackle the parameter estimation of multivariate t distribution models
in the EML approach. Since the evolutionary optimizer does not rely
on gradient search, the EML approach can be applied to estimation of
more complicated copula models such as high-dimensional copulas.
Our experimental study shows that the proposed method provides
more robust and more accurate estimates as compared to the IFM
approach.
Abstract: Fertilization plays an important role in crop growth and soil improvement. This study was conducted to determine the best fertilization system for wheat production. Experiments were arranged in a complete block design with three replications in two years. Main plots consisted of six methods of fertilization including (N1): farmyard manure; (N2): compost; (N3): chemical fertilizers; (N4): farmyard manure + compost; (N5): farmyard manure + compost + chemical fertilizers and (N6): control were arranged in sub plots. The addition of compost or farm yard manure significantly increased the soil microbial biomass carbon in comparison to the chemical fertilizer. The dehydrogenase, phosphatase and urease activities in the N3 treatment were significantly lower than in the farm yard manure and compost treatments.
Abstract: This experiment was conducted in attempt of
improving hydrodynamic efficiency of the propulsion mechanism by
installing a spring to the wing so that the opening angle of the wing in
one stroke can be changed automatically, compared to the existing
method of fixed maximum opening angle in Weis-Fogh type ship
propulsion mechanism. Average thrust coefficient was almost fixed
with all velocity ratio with the prototype, but with the spring type,
thrust coefficient increased sharply as velocity ratio increased.
Average propulsive efficiency was larger with bigger opening angle in
the prototype, but in the spring type, the one with smaller spring
coefficient had larger value. In the range over 1.0 in velocity ratio
where big thrust can be generated, spring type had more than twice of
propulsive efficiency increase compared to the prototype.
Abstract: This study experimentally and numerically investigates
motor cooling performance. The motor consists of a centrifugal fan,
two axial fans, a shaft, a stator, a rotor and a heat exchanger with 637
cooling tubes. The pressure rise-flow rate (P-Q) performance curves of
the cooling fans at 1800 rpm are tested using a test apparatus
complying with the Chinese National Standard (CNS) 2726.
Compared with the experimental measurements, the numerical
analysis results show that the P-Q performance curves of the axial fan
and centrifugal fan can be estimated within about 2% and 6%,
respectively. By using the simplified model, setting up the heat
exchanger and stator as porous media, the flow field in the motor is
calculated. By using the results of the flow field near the rotor and
stator, and subjecting the heat generation rate as a boundary condition,
the temperature distributions of the stator and rotor are also calculated.
The simulation results show that the calculated temperature of the
stator winding near the axial fans is lower by about 5% than the
measured value, and the calculated temperature of the stator core
located at the center of the stator is about 1% higher than the measured
value. Besides, discussion is made to improve the motor cooling
performance.
Abstract: In this paper, we present a robust and secure
algorithm for watermarking, the watermark is first transformed into
the frequency domain using the discrete wavelet transform (DWT).
Then the entire DWT coefficient except the LL (Band) discarded,
these coefficients are permuted and encrypted by specific mixing.
The encrypted coefficients are inserted into the most significant
spectral components of the stego-image using a chaotic system. This
technique makes our watermark non-vulnerable to the attack (like
compression, and geometric distortion) of an active intruder, or due
to noise in the transmission link.
Abstract: In this study the mixed mode fracture mechanics
parameters were investigated for high tensile steel butt welded joint
based on modified Arcan test and finite element analysis was used to
evaluate the effect of crack length on fracture criterion. The nondimensional
stress intensity factors, strain energy release rates and Jintegral
energy on crack tip were obtained for various in-plane
loading combinations on Arcan specimen starting from pure mode-I
to pure mode-II loading conditions. The specimen and apparatus were
modeled by finite element method and analyzed under various
loading angles (between 0 to 90 degrees with 15 degree interval) to
simulate the pure mode-I, II and mixed mode fracture. Since the
analytical results are independent from elasticity modules for
isotropic materials, therefore the results in elastic fields can be used
for Arcan specimens. The main objective of this study was to
evaluate the geometric calibration factors for modified Arcan test
specimen in order to obtain fracture toughness under mixed mode
loading conditions.
Abstract: New Growth Theory helps us make sense of the
ongoing shift from a resource-based economy to a knowledge-based
economy. It underscores the point that the economic processes which
create and diffuse new knowledge are critical to shaping the growth
of nations, communities and individual firms. In all too many
contributions to New (Endogenous) Growth Theory – though not in
all – central reference is made to 'a stock of knowledge', a 'stock of
ideas', etc., this variable featuring centre-stage in the analysis. Yet it
is immediately apparent that this is far from being a crystal clear
concept. The difficulty and uncertainty of being able to capture the
value associated with knowledge is a real problem. The intent of this
paper is introducing new thinking and theorizing about the
knowledge and its measurability in new growth theory. Moreover the
study aims to synthesize various strain of the literature with a
practical bearing on knowledge concept. By contribution of
institution framework which is found within NGT, we can indirectly
measure the knowledge concept. Institutions matter because they
shape the environment for production and employment of new
knowledge
Abstract: The paper deals with the most important changes that have occurred in business because of social media and its impact on organisations and leadership in recent years. It seeks to synthesize existing research, theories and concepts, in order to understand "social destinations", and to provide a bridge from past research to future success. Becoming a "social destination" is a strategic and tactical leadership and management issue and the paper will present the importance of destination leadership in choosing the way towards a social destination and some organisational models. It also presents some social media tools that can be used in transforming a destination into a social one. Adapting organisations to the twentyfirst century means adopting social media as a way of life and a way of business.
Abstract: This paper discusses the design characteristics management accounting systems should have to be useful for strategic planning and control and provides brief introductions to strategic variance analysis, profit-linked performance measurement models and balanced scorecard. It shows two multi-period, multiproduct models are specified, can be related to Porter's strategy framework and cost and revenue drivers, and can be used to support strategic planning, control and cost management.