Abstract: The literature reports a large number of approaches for
measuring the similarity between protein sequences. Most of these
approaches estimate this similarity using alignment-based techniques
that do not necessarily yield biologically plausible results, for two
reasons.
First, for the case of non-alignable (i.e., not yet definitively aligned
and biologically approved) sequences such as multi-domain, circular
permutation and tandem repeat protein sequences, alignment-based
approaches do not succeed in producing biologically plausible results.
This is due to the nature of the alignment, which is based on the
matching of subsequences in equivalent positions, while non-alignable
proteins often have similar and conserved domains in non-equivalent
positions.
Second, the alignment-based approaches lead to similarity measures
that depend heavily on the parameters set by the user for the alignment
(e.g., gap penalties and substitution matrices). For easily alignable
protein sequences, it's possible to supply a suitable combination of
input parameters that allows such an approach to yield biologically
plausible results. However, for difficult-to-align protein sequences,
supplying different combinations of input parameters yields different
results. Such variable results create ambiguities and complicate the
similarity measurement task.
To overcome these drawbacks, this paper describes a novel and
effective approach for measuring the similarity between protein
sequences, called SAF for Substitution and Alignment Free. Without
resorting either to the alignment of protein sequences or to substitution
relations between amino acids, SAF is able to efficiently detect the
significant subsequences that best represent the intrinsic properties of
protein sequences, those underlying the chronological dependencies of
structural features and biochemical activities of protein sequences.
Moreover, by using a new efficient subsequence matching scheme,
SAF more efficiently handles protein sequences that contain similar
structural features with significant meaning in chronologically
non-equivalent positions. To show the effectiveness of SAF, extensive
experiments were performed on protein datasets from different
databases, and the results were compared with those obtained by
several mainstream algorithms.
Abstract: E-travel is travel agency-s companies employing internet and website as e-commerce context. This study presents numerous initial key factors of electronic travel model based on small travel agencies perspectives. Browsing previous studies related to website travel activities are conducted. Five small travel agencies in Indonesia has been deeply interviewed in case studies. The finding of this research is identifying numerous characteristics and dimension factors and travel website operations including ownermanager roles, business experiences, characteristically business, and technological aspects. This study is the preliminary research related to travel website adoption in Indonesia. The further study would be conducted in questionnaires of the quantitative research in Indonesia contexts as a developing country.
Abstract: We study in this paper the effect of the scene
changing on image sequences coding system using Embedded
Zerotree Wavelet (EZW). The scene changing considered here is the
full motion which may occurs. A special image sequence is generated
where the scene changing occurs randomly. Two scenarios are
considered: In the first scenario, the system must provide the
reconstruction quality as best as possible by the management of the
bit rate (BR) while the scene changing occurs. In the second scenario,
the system must keep the bit rate as constant as possible by the
management of the reconstruction quality. The first scenario may be
motivated by the availability of a large band pass transmission
channel where an increase of the bit rate may be possible to keep the
reconstruction quality up to a given threshold. The second scenario
may be concerned by the narrow band pass transmission channel
where an increase of the bit rate is not possible. In this last case,
applications for which the reconstruction quality is not a constraint
may be considered. The simulations are performed with five scales
wavelet decomposition using the 9/7-tap filter bank biorthogonal
wavelet. The entropy coding is performed using a specific defined
binary code book and EZW algorithm. Experimental results are
presented and compared to LEAD H263 EVAL. It is shown that if
the reconstruction quality is the constraint, the system increases the
bit rate to obtain the required quality. In the case where the bit rate
must be constant, the system is unable to provide the required quality
if the scene change occurs; however, the system is able to improve
the quality while the scene changing disappears.
Abstract: MATCH project [1] entitle the development of an
automatic diagnosis system that aims to support treatment of colon
cancer diseases by discovering mutations that occurs to tumour
suppressor genes (TSGs) and contributes to the development of
cancerous tumours. The constitution of the system is based on a)
colon cancer clinical data and b) biological information that will be
derived by data mining techniques from genomic and proteomic
sources The core mining module will consist of the popular, well
tested hybrid feature extraction methods, and new combined
algorithms, designed especially for the project. Elements of rough
sets, evolutionary computing, cluster analysis, self-organization maps
and association rules will be used to discover the annotations
between genes, and their influence on tumours [2]-[11].
The methods used to process the data have to address their high
complexity, potential inconsistency and problems of dealing with the
missing values. They must integrate all the useful information
necessary to solve the expert's question. For this purpose, the system
has to learn from data, or be able to interactively specify by a domain
specialist, the part of the knowledge structure it needs to answer a
given query. The program should also take into account the
importance/rank of the particular parts of data it analyses, and adjusts
the used algorithms accordingly.
Abstract: In this paper, we introduce GODYS-PC software
package for modeling, simulating and analyzing dynamic systems.
To illustrate the use of GODYS-PC we present a few examples
which concern modeling and simulating of engineering systems. In
order to compare GODYS-PC with widely used in academia and
industry Simulink®, the same examples are provided both in
GODYS-PC and Simulink®.
Abstract: The major part of light weight timber constructions
consists of insulation. Mineral wool is the most commonly used
insulation due to its cost efficiency and easy handling. The fiber
orientation and porosity of this insulation material enables flowthrough.
The air flow resistance is low. If leakage occurs in the
insulated bay section, the convective flow may cause energy losses
and infiltration of the exterior wall with moisture and particles. In
particular the infiltrated moisture may lead to thermal bridges and
growth of health endangering mould and mildew. In order to prevent
this problem, different numerical calculation models have been
developed. All models developed so far have a potential for
completion. The implementation of the flow-through properties of
mineral wool insulation may help to improve the existing models.
Assuming that the real pressure difference between interior and
exterior surface is larger than the prescribed pressure difference in the
standard test procedure for mineral wool ISO 9053 / EN 29053,
measurements were performed using the measurement setup for
research on convective moisture transfer “MSRCMT".
These measurements show, that structural inhomogeneities of
mineral wool effect the permeability only at higher pressure
differences, as applied in MSRCMT. Additional microscopic
investigations show, that the location of a leak within the
construction has a crucial influence on the air flow-through and the
infiltration rate. The results clearly indicate that the empirical values
for the acoustic resistance of mineral wool should not be used for the
calculation of convective transfer mechanisms.
Abstract: Literature reveals that many investors rely on technical trading rules when making investment decisions. If stock markets are efficient, one cannot achieve superior results by using these trading rules. However, if market inefficiencies are present, profitable opportunities may arise. The aim of this study is to investigate the effectiveness of technical trading rules in 34 emerging stock markets. The performance of the rules is evaluated by utilizing White-s Reality Check and the Superior Predictive Ability test of Hansen, along with an adjustment for transaction costs. These tests are able to evaluate whether the best model performs better than a buy-and-hold benchmark. Further, they provide an answer to data snooping problems, which is essential to obtain unbiased outcomes. Based on our results we conclude that technical trading rules are not able to outperform a naïve buy-and-hold benchmark on a consistent basis. However, we do find significant trading rule profits in 4 of the 34 investigated markets. We also present evidence that technical analysis is more profitable in crisis situations. Nevertheless, this result is relatively weak.
Abstract: This paper reports the tensile fracture location
characterizations of dissimilar friction stir welds between 5754
aluminium alloy and C11000 copper. The welds were produced using
three shoulder diameter tools; namely, 15, 18 and 25 mm by varying
the process parameters. The rotational speeds considered were 600,
950 and 1200 rpm while the feed rates employed were 50, 150 and
300 mm/min to represent the low, medium and high settings
respectively. The tensile fracture locations were evaluated using the
optical microscope to identify the fracture locations and were
characterized. It was observed that 70% of the tensile samples failed
in the Thermo Mechanically Affected Zone (TMAZ) of copper at the
weld joints. Further evaluation of the fracture surfaces of the pulled
tensile samples revealed that welds with low Ultimate Tensile
Strength either have defects or intermetallics present at their joint
interfaces.
Abstract: One of the major, difficult tasks in automated video
surveillance is the segmentation of relevant objects in the scene.
Current implementations often yield inconsistent results on average
from frame to frame when trying to differentiate partly occluding
objects. This paper presents an efficient block-based segmentation
algorithm which is capable of separating partly occluding objects and
detecting shadows. It has been proven to perform in real time with a
maximum duration of 47.48 ms per frame (for 8x8 blocks on a
720x576 image) with a true positive rate of 89.2%. The flexible
structure of the algorithm enables adaptations and improvements with
little effort. Most of the parameters correspond to relative differences
between quantities extracted from the image and should therefore not
depend on scene and lighting conditions. Thus presenting a
performance oriented segmentation algorithm which is applicable in
all critical real time scenarios.
Abstract: The harmonic Arnoldi method can be used to find interior eigenpairs of large matrices. However, it has been shown that this method may converge erratically and even may fail to do so. In this paper, we present a new method for computing interior eigenpairs of large nonsymmetric matrices, which is called weighted harmonic Arnoldi method. The implementation of the method has been tested by numerical examples, the results show that the method converges fast and works with high accuracy.
Abstract: A basic conceptual study of TCSC device on Simulink is a teaching aid and helps in understanding the rudiments of the topic. This paper thus stems out from basics of TCSC device and analyzes the impedance characteristics and associated single & multi resonance conditions. The Impedance characteristics curve is drawn for different values of inductance in MATLAB using M-files. The study is also helpful in estimating the appropriate inductance and capacitance values which have influence on multi resonance point in TCSC device. The capacitor voltage, line current, thyristor current and capacitor current waveforms are discussed briefly as simulation results. Simulink model of TCSC device is given and corresponding waveforms are analyzed. The subsidiary topics e.g. power oscillation damping, SSR mitigation and transient stability is also brought out.
Abstract: In this work, the physical based device model of
AlGaN/GaN high electron mobility transistors (HEMTs) has been
established and the corresponding device operation behavior has
been investigated also by using Sentaurus TCAD from Synopsys.
Advanced AlGaN/GaN hetero-structures with GaN cap layer and AlN
spacer have been considered and the GaN cap layer and AlN spacer
are found taking important roles on the gate leakage blocking and
off-state breakdown voltage enhancement.
Abstract: As part of national epidemiological survey on bovine
viral diarrhea virus (BVDV), a total of 274 dejecta samples were
collected from 14 cattle farms in 8 areas of Xinjiang Uygur
Autonomous Region in northwestern China. Total RNA was extracted
from each sample, and 5--untranslated region (UTR) of BVDV
genome was amplified by using two-step reverse
transcriptase-polymerase chain reaction (RT-PCR). The PCR products
were subsequently sequenced to study the genetic variations of BVDV
in these areas. Among the 274 samples, 33 samples were found
virus-positive. According to sequence analysis of the PCR products,
the 33 samples could be arranged into 16 groups. All the sequences,
however, were highly conserved with BVDV Osloss strains. The virus
possessed theses sequences belonged to BVDV-1b subtype by
phylogenetic analysis. Based on these data, we established a typing
tree for BVDV in these areas. Our results suggested that BVDV-1b
was a predominant subgenotype in northwestern China and no
correlation between the genetic and geographical distances could be
observed above the farm level.
Abstract: The paper provides an in-depth tutorial of mathematical
construction of maximal length sequences (m-sequences) via primitive
polynomials and how to map the same when implemented in
shift registers. It is equally important to check whether a polynomial
is primitive or not so as to get proper m-sequences. A fast method to
identify primitive polynomials over binary fields is proposed where
the complexity is considerably less in comparison with the standard
procedures for the same purpose.
Abstract: Palestinian cities face the challenges of land scarcity,
high population growth rates, rapid urbanization, uneven
development and territorial fragmentation. Due to geopolitical
constrains and the absence of an effective Palestinian planning
institution, urban development in Palestinian cities has not followed
any discernable planning scheme. This has led to a number of
internal contradictions in the structure of cities, and adversely
affected land use, the provision of urban services, and the quality of
the living environment.
This paper explores these challenges, and the potential that exists
for introducing a more sustainable urban development pattern in
Palestinian cities. It assesses alternative development approaches
with a particular focus on sustainable development, promoting ecodevelopment
imperatives, limiting random urbanization, and meeting
present and future challenges, including fulfilling the needs of the
people and conserving the scarce land and limited natural resources.
This paper concludes by offering conceptual proposals and guidelines
for promoting sustainable physical development in Palestinian cities.
Abstract: The usage of internet is rapidly increasing and the usage of mobile agent technology in internet environment has a great demand. The security issue one of main obstacles that restrict the mobile agent technology to spread. This paper proposes Secure-Image Mechanism (SIM) as a new mechanism to protect mobile agents against malicious hosts. . SIM aims to protect mobile agent by using the symmetric encryption and hash function in cryptography science. This mechanism can prevent the eavesdropping and alteration attacks. It assists the mobile agents to continue their journey normally incase attacks occurred.
Abstract: Bonding has become a routine procedure in several
dental specialties – from prosthodontics to conservative dentistry and
even orthodontics. In many of these fields it is important to be able to
investigate the bonded interfaces to assess their quality. All currently
employed investigative methods are invasive, meaning that samples
are destroyed in the testing procedure and cannot be used again. We
have investigated the interface between human enamel and bonded
ceramic brackets non-invasively, introducing a combination of new
investigative methods – optical coherence tomography (OCT),
fluorescence OCT and confocal microscopy (CM). Brackets were
conventionally bonded on conditioned buccal surfaces of teeth. The
bonding was assessed using these methods. Three dimensional
reconstructions of the detected material defects were developed using
manual and semi-automatic segmentation. The results clearly prove
that OCT, fluorescence OCT and CM are useful in orthodontic
bonding investigations.
Abstract: Power loss reduction is one of the main targets in power industry and so in this paper, the problem of finding the optimal configuration of a radial distribution system for loss reduction is considered. Optimal reconfiguration involves the selection of the best set of branches to be opened ,one each from each loop, for reducing resistive line losses , and reliving overloads on feeders by shifting the load to adjacent feeders. However ,since there are many candidate switching combinations in the system ,the feeder reconfiguration is a complicated problem. In this paper a new approach is proposed based on a simple optimum loss calculation by determining optimal trees of the given network. From graph theory a distribution network can be represented with a graph that consists a set of nodes and branches. In fact this problem can be viewed as a problem of determining an optimal tree of the graph which simultaneously ensure radial structure of each candidate topology .In this method the refined genetic algorithm is also set up and some improvements of algorithm are made on chromosome coding. In this paper an implementation of the algorithm presented by [7] is applied by modifying in load flow program and a comparison of this method with the proposed method is employed. In [7] an algorithm is proposed that the choice of the switches to be opened is based on simple heuristic rules. This algorithm reduce the number of load flow runs and also reduce the switching combinations to a fewer number and gives the optimum solution. To demonstrate the validity of these methods computer simulations with PSAT and MATLAB programs are carried out on 33-bus test system. The results show that the performance of the proposed method is better than [7] method and also other methods.
Abstract: In this paper, an improved edge detection algorithm
based on fuzzy combination of mathematical morphology and
wavelet transform is proposed. The combined method is proposed to
overcome the limitation of wavelet based edge detection and
mathematical morphology based edge detection in noisy images.
Experimental results show superiority of the proposed method, as
compared to the traditional Prewitt, wavelet based and morphology
based edge detection methods. The proposed method is an effective
edge detection method for noisy image and keeps clear and
continuous edges.
Abstract: The potential, opportunities and drawbacks of biogas
technology use in Turkey are evaluated in this paper. Turkey is
dependent on foreign sources of energy. Therefore, use of biogas
technology would provide a safe way of waste disposal and recovery
of renewable energy, particularly from a sustainable domestic source,
which is less unlikely to be influenced by international price or
political fluctuations. Use of biogas technology would especially
meet the cooking, heating and electricity demand in rural areas and
protect the environment, additionally creating new job opportunities
and improving social-economical conditions.