Abstract: The Roma (Gypsies) is a transnational minority with a
high degree of consanguineous marriages. Similar to other
genetically isolated founder populations, the Roma harbor a number
of unique or rare genetic disorders. This paper discusses about a rare
form of Charcot-Marie-Tooth disease – type 4G (CMT4G), also
called Hereditary Motor and Sensory Neuropathy type Russe, an
autosomal recessive disease caused by mutation private to Roma
characterized by abnormally increased density of non-myelinated
axons. CMT4G was originally found in Bulgarian Roma and in 2009
two putative causative mutations in the HK1 gene were identified.
Since then, several cases were reported in Roma families mainly
from Bulgaria and Spain. Here we present a Slovak Roma family in
which CMT4G was diagnosed on the basis of clinical examination
and genetic testing. This case is a further proof of the role of the HK1
gene in pathogenesis of the disease. It confirms that mutation in the
HK1 gene is a common cause of autosomal recessive CMT disease in
Roma and should be considered as a common part of a diagnostic
procedure.
Abstract: Monoamine oxidase A gene (MAOA) is suggested to
be a candidate gene implicated in many neuropsychiatric disorders,
including autism spectrum disorder (ASD). This meta-analytic review
evaluates the relationship between ASD and MAOA markers such as
30 bp variable number tandem repeats in the promoter region
(uVNTR) and single nucleotide polymorphisms (SNPs) by using
findings from recently published studies. It seems that in Caucasian
males, the risk of developing ASD increase with the presence of 4-
repeat allele in the promoter region of MAOA gene whereas no
differences were found between autistic patients and controls in
Egyptian, West Bengal and Korean population. Some studies point to
the importance of specific haplotype groups of SNPs and interaction
of MAOA with others genes (e. g. FOXP2 or SRY). The results of
existing studies are insufficient and further research is needed.
Abstract: Environmental impacts of six 3D printers using
various materials were compared to determine if material choice
drove sustainability, or if other factors such as machine type, machine
size, or machine utilization dominate. Cradle-to-grave life-cycle
assessments were performed, comparing a commercial-scale FDM
machine printing in ABS plastic, a desktop FDM machine printing in
ABS, a desktop FDM machine printing in PET and PLA plastics, a
polyjet machine printing in its proprietary polymer, an SLA machine
printing in its polymer, and an inkjet machine hacked to print in salt
and dextrose. All scenarios were scored using ReCiPe Endpoint H
methodology to combine multiple impact categories, comparing
environmental impacts per part made for several scenarios per
machine. Results showed that most printers’ ecological impacts were
dominated by electricity use, not materials, and the changes in
electricity use due to different plastics was not significant compared
to variation from one machine to another. Variation in machine idle
time determined impacts per part most strongly. However, material
impacts were quite important for the inkjet printer hacked to print in
salt: In its optimal scenario, it had up to 1/38th the impacts coreper
part as the worst-performing machine in the same scenario. If salt
parts were infused with epoxy to make them more physically robust,
then much of this advantage disappeared, and material impacts
actually dominated or equaled electricity use. Future studies should
also measure DMLS and SLS processes / materials.
Abstract: One of the major difficulties introduced with wind
power penetration is the inherent uncertainty in production originating
from uncertain wind conditions. This uncertainty impacts many
different aspects of power system operation, especially the balancing
power requirements. For this reason, in power system development
planing, it is necessary to evaluate the potential uncertainty in future
wind power generation. For this purpose, simulation models are
required, reproducing the performance of wind power forecasts.
This paper presents a wind power forecast error simulation models
which are based on the stochastic process simulation. Proposed
models capture the most important statistical parameters recognized
in wind power forecast error time series. Furthermore, two distinct
models are presented based on data availability. First model uses
wind speed measurements on potential or existing wind power plant
locations, while the seconds model uses statistical distribution of wind
speeds.
Abstract: Measurements and quantitative analysis of kinematic
parameters of human hand movements have an important role in
different areas such as hand function rehabilitation, modeling of
multi-digits robotic hands, and the development of machine-man
interfaces. In this paper the assessment and evaluation of the reachto-
grasp movement by using computerized and robot-assisted method
is described. Experiment involved the measurements of hand
positions of seven healthy subjects during grasping three objects of
different shapes and sizes. Results showed that three dominant phases
of reach-to-grasp movements could be clearly identified.
Abstract: It is difficult to study the effect of various variables on
cycle fitting through actual experiment. To overcome such difficulty,
the forward dynamics of a musculoskeletal model was applied to cycle
fitting in this study. The measured EMG data weres compared with the
muscle activities of the musculoskeletal model through forward
dynamics. EMG data were measured from five cyclists who do not
have musculoskeletal diseases during three minutes pedaling with a
constant load (150 W) and cadence (90 RPM). The muscles used for
the analysis were the Vastus Lateralis (VL), Tibialis Anterior (TA),
Bicep Femoris (BF), and Gastrocnemius Medial (GM). Person’s
correlation coefficients of the muscle activity patterns, the peak timing
of the maximum muscle activities, and the total muscle activities were
calculated and compared. BIKE3D model of AnyBody (Anybodytech,
Denmark) was used for the musculoskeletal model simulation. The
comparisons of the actual experiments with the simulation results
showed significant correlations in the muscle activity patterns (VL:
0.789, TA: 0.503, BF: 0.468, GM: 0.670). The peak timings of the
maximum muscle activities were distributed at particular phases. The
total muscle activities were compared with the normalized muscle
activities, and the comparison showed about 10% difference in the VL
(+10%), TA (+9.7%), and BF (+10%), excluding the GM (+29.4%).
Thus, it can be concluded that muscle activities of model &
experiment showed similar results. The results of this study indicated
that it was possible to apply the simulation of further improved
musculoskeletal model to cycle fitting.
Abstract: Alkylated silicon nanocrystals (C11-SiNCs) were
prepared successfully by galvanostatic etching of p-Si(100) wafers
followed by a thermal hydrosilation reaction of 1-undecene in
refluxing toluene in order to extract C11-SiNCs from porous silicon.
Erbium trichloride was added to alkylated SiNCs using a simple
mixing chemical route. To the best of our knowledge, this is the first
investigation on mixing SiNCs with erbium ions (III) by this
chemical method. The chemical characterization of C11-SiNCs and
their mixtures with Er3+(Er/C11-SiNCs) were carried out using X-ray
photoemission spectroscopy (XPS). The optical properties of C11-
SiNCs and their mixtures with Er3+ were investigated using Raman
spectroscopy and photoluminescence (PL). The erbium mixed
alkylated SiNCs shows an orange PL emission peak at around 595
nm that originates from radiative recombination of Si. Er/C11-SiNCs
mixture also exhibits a weak PL emission peak at 1536 nm that
originates from the intra-4f transition in erbium ions (Er3+). The PL
peak of Si in Er/C11-SiNCs mixture is increased in the intensity up to
three times as compared to pure C11-SiNCs. The collected data
suggest that this chemical mixing route leads instead to a transfer of
energy from erbium ions to alkylated SiNCs.
Abstract: Modular structural systems are constructed using a
method that they are assembled with prefabricated unit modular
frames on-site. This provides a benefit that can significantly reduce
building construction time. The structural design is usually carried out
under the assumption that their load-carrying mechanism is similar to
that of traditional steel moment-resisting systems. However, both
systems are different in terms of beam-column connection details
which may strongly influence the lateral structural behavior. Specially,
the presence of access holes in a beam-column joint of a unit modular
frame could cause undesirable failure during strong earthquakes.
Therefore, this study carried out finite element analyses (FEMs) of
unit modular frames to investigate the cyclic behavior of beam-column
joints with the access holes. Analysis results show that the unit
modular frames present stable cyclic response with large deformation
capacities and their joints are classified into semi-rigid connections
even if there are access holes.
Abstract: The Simulation based VLSI Implementation of
FELICS (Fast Efficient Lossless Image Compression System)
Algorithm is proposed to provide the lossless image compression and
is implemented in simulation oriented VLSI (Very Large Scale
Integrated). To analysis the performance of Lossless image
compression and to reduce the image without losing image quality
and then implemented in VLSI based FELICS algorithm. In FELICS
algorithm, which consists of simplified adjusted binary code for
Image compression and these compression image is converted in
pixel and then implemented in VLSI domain. This parameter is used
to achieve high processing speed and minimize the area and power.
The simplified adjusted binary code reduces the number of arithmetic
operation and achieved high processing speed. The color difference
preprocessing is also proposed to improve coding efficiency with
simple arithmetic operation. Although VLSI based FELICS
Algorithm provides effective solution for hardware architecture
design for regular pipelining data flow parallelism with four stages.
With two level parallelisms, consecutive pixels can be classified into
even and odd samples and the individual hardware engine is
dedicated for each one. This method can be further enhanced by
multilevel parallelisms.
Abstract: Passing the entrance exam to a university is a major
step in one's life. University entrance exam commonly known as
Kankor is the nationwide entrance exam in Afghanistan. This
examination is prerequisite for all public and private higher education
institutions at undergraduate level. It is usually taken by students who
are graduated from high schools. In this paper, we reflect the major
educational school graduates issues and propose ICT-based test
preparation environment, known as ‘Online Kankor Exam Prep
System’ to give students the tools to help them pass the university
entrance exam on the first try. The system is based on Intelligent
Tutoring System (ITS), which introduced an essential package of
educational technology for learners that features: (I) exam-focused
questions and content; (ii) self-assessment environment; and (iii) test
preparation strategies in order to help students to acquire the necessary
skills in their carrier and keep them up-to-date with instruction.
Abstract: This paper identifies limitations of existing two e-
Governance services viz. railway ticket booking and passport service
in India. The comparison has been made as to how in the past these
two citizen services were operating manually and how these services
are taken online via e-Governance. Different e-Governance projects,
investment aspects, and role of corporate are discussed. For Indian
Railway online ticketing a comparison has been made between state
run booking website and popular private firm run booking websites.
For passport service, observations through personal visit to passport
center is described. Suggestions are made to improve these services
further to improve citizen service experiences.
Abstract: In this paper, extract of papaya leaves are used as a
natural dye and combined by variations of solvent concentration
applied on DSSC (Dye-Sensitized Solar Cell). Indonesian geographic
located on the equator line occasions the magnitude of the potential
to develop organic solar cells made from extracts of chlorophyll as a
substitute for inorganic materials or synthetic dye on DSSC material.
Dye serves as absorbing photons which are then converted into
electrical energy. A conductive coated glass layer called TCO
(Transparent Conductive Oxide) is used as a substrate of electrode.
TiO2 nanoparticles as binding dye molecules, redox couple iodide/
tri-iodide as the electrolyte and carbon as the counter electrode in the
DSSC are used. TiO2 nanoparticles, organic dyes, electrolytes, and
counter electrode are arranged and combined with the layered
structure of the photo-catalyst absorption layer. Dye absorption
measurements using a spectrophotometer at 400-800 nm light
spectrum produces a total amount of chlorophyll 80.076 mg/l. The
test cell at 7 watt LED light with 5000 lux luminescence was
obtained Voc and Isc of 235.5 mV and 14 μA, respectively.
Abstract: This paper describes a novel application of Fiber
Braggs Grating (FBG) sensors in the assessment of human postural
stability and balance on an unstable platform. In this work, FBG
sensor Stability Analyzing Device (FBGSAD) is developed for
measurement of plantar strain to assess the postural stability of
subjects on unstable platforms during different stances in eyes open
and eyes closed conditions on a rocker board. The studies are
validated by comparing the Centre of Gravity (CG) variations
measured on the lumbar vertebra of subjects using a commercial
accelerometer. The results obtained from the developed FBGSAD
depict qualitative similarities with the data recorded by commercial
accelerometer. The advantage of the FBGSAD is that it measures
simultaneously plantar strain distribution and postural stability of the
subject along with its inherent benefits like non-requirement of
energizing voltage to the sensor, electromagnetic immunity and
simple design which suits its applicability in biomechanical
applications. The developed FBGSAD can serve as a tool/yardstick to
mitigate space motion sickness, identify individuals who are
susceptible to falls and to qualify subjects for balance and stability,
which are important factors in the selection of certain unique
professionals such as aircraft pilots, astronauts, cosmonauts etc.
Abstract: We have developed a new computer program in
Fortran 90, in order to obtain numerical solutions of a system
of Relativistic Magnetohydrodynamics partial differential equations
with predetermined gravitation (GRMHD), capable of simulating
the formation of relativistic jets from the accretion disk of matter
up to his ejection. Initially we carried out a study on numerical
methods of unidimensional Finite Volume, namely Lax-Friedrichs,
Lax-Wendroff, Nessyahu-Tadmor method and Godunov methods
dependent on Riemann problems, applied to equations Euler in
order to verify their main features and make comparisons among
those methods. It was then implemented the method of Finite
Volume Centered of Nessyahu-Tadmor, a numerical schemes that
has a formulation free and without dimensional separation of
Riemann problem solvers, even in two or more spatial dimensions,
at this point, already applied in equations GRMHD. Finally, the
Nessyahu-Tadmor method was possible to obtain stable numerical
solutions - without spurious oscillations or excessive dissipation -
from the magnetized accretion disk process in rotation with respect
to a central black hole (BH) Schwarzschild and immersed in a
magnetosphere, for the ejection of matter in the form of jet over a
distance of fourteen times the radius of the BH, a record in terms
of astrophysical simulation of this kind. Also in our simulations,
we managed to get substructures jets. A great advantage obtained
was that, with the our code, we got simulate GRMHD equations in
a simple personal computer.
Abstract: In previous study, technique to estimate a self-location by using a lunar image is proposed.We consider the improvement of the conventional method in consideration of FPGA implementationin this paper. Specifically, we introduce Artificial Bee Colony algorithm for reduction of search time.In addition, we use fixed point arithmetic to enable high-speed operation on FPGA.
Abstract: In this article, we have elaborated a study over the
nature of financial intermediation in Islamic banks by comparison to
those of conventional ones. We have found a striking difference
between two kinds of intermediation. We tried, from another side, to
study the relationship between the capital level and deficiency risk
relying on econometric model, and we have obtained a positive and
significant relation between the capital and the deficiency risk for the
conventional banks. This means that when the capital of these banks
increases, the deficiency risk increases as well. In return, since the
Islamic banks are constrained to respect the Sharia Committee as well
as customers’ demands that may, in certain contracts, choose to
invest their capitals in projects they are interested in. These
constraints have as effects to reduce the deficiency risk even when
the capital increases.
Abstract: The most important component affecting the
efficiency of photovoltaic power systems are solar panels. In other
words, efficiency of these systems are significantly affected due to
the being low efficiency of solar panel. Thus, solar panels should be
operated under maximum power point conditions through a power
converter. In this study, design of boost converter has been carried
out with maximum power point tracking (MPPT) algorithm which is
incremental conductance (Inc-Cond). By using this algorithm,
importance of power converter in MPPT hardware design, impacts of
MPPT operation have been shown. It is worth noting that initial
operation point is the main criteria for determining the MPPT
performance. In addition, it is shown that if value of load resistance is
lower than critical value, failure operation is realized. For these
analyzes, direct duty control is used for simplifying the control.
Abstract: Nowadays, the successful implementation of ICTs is
vital for almost any kind of organization. Good governance and ICT
management are essential for delivering value, managing
technological risks, managing resources and performance
measurement. In addition, outsourcing is a strategic IT service
solution which complements IT services provided internally in
organizations. This paper proposes the measurement tools of a new
holistic maturity model based on standards ISO/IEC 20000 and
ISO/IEC 38500, and the frameworks and best practices of ITIL and
COBIT, with a specific focus on IT outsourcing. These measurement
tools allow independent validation and practical application in the
field of higher education, using a questionnaire, metrics tables, and
continuous improvement plan tables as part of the measurement
process. Guidelines and standards are proposed in the model for
facilitating adaptation to universities and achieving excellence in the
outsourcing of IT services.
Abstract: This paper presents optimization of makespan for ‘n’
jobs and ‘m’ machines flexible job shop scheduling problem with
sequence dependent setup time using genetic algorithm (GA)
approach. A restart scheme has also been applied to prevent the
premature convergence. Two case studies are taken into
consideration. Results are obtained by considering crossover
probability (pc = 0.85) and mutation probability (pm = 0.15). Five
simulation runs for each case study are taken and minimum value
among them is taken as optimal makespan. Results indicate that
optimal makespan can be achieved with more than one sequence of
jobs in a production order.
Abstract: Since large part of electricity is generated by using
fossil based resources, energy is an important agenda for countries. In
this context, renewable energy sources are alternative to conventional
sources due to the depletion of fossil resources, increasing awareness
of climate change and global warming concerns. Solar, wind and
hydropower energy are the main renewable energy sources. Among
of them, since installed capacity of wind power has increased
approximately eight times between 2008 - November of 2014, wind
energy is a promising source for Turkey. Furthermore, signing of
Kyoto Protocol can be accepted as a milestone for Turkey's energy
policy. Turkish Government has announced Vision 2023 (energy
targets by 2023) in 2010-2014 Strategic Plan prepared by Ministry of
Energy and Natural Resources (MENR). Energy targets in this plan
can be summarized as follows: Share of renewable energy sources in
electricity generation is 30% of total electricity generation by 2023.
Installed capacity of wind energy will be 20 GW by 2023. Other
renewable energy sources such as solar, hydropower and geothermal
are encouraged with new incentive mechanisms. Dependence on
foreign energy is reduced for sustainability and energy security. On
the other hand, since Turkey is surrounded by three coastal areas,
wind energy potential is convenient for wind power application. As
of November of 2014, total installed capacity of wind power plants is
3.51 GW and a lot of wind power plants are under construction with
capacity 1.16 GW. Turkish government also encourages the locally
manufactured equipments. In this context, one of the projects funded
by private sector, universities and TUBİTAK names as MILRES is
an important project aimed to promote the use wind energy in
electricity generation. Within this project, wind turbine with 500 kW
power has been produced and will be installed at the beginning of the
2015. After that, by using the experience obtained from the first
phase of the project, a wind turbine with 2.5 MW power will be
manufactured in an industrial scale.