Abstract: In molecular biology, microarray technology is widely and successfully utilized to efficiently measure gene activity. If working with less studied organisms, methods to design custom-made microarray probes are available. One design criterion is to select probes with minimal melting temperature variances thus ensuring similar hybridization properties. If the microarray application focuses on the investigation of metabolic pathways, it is not necessary to cover the whole genome. It is more efficient to cover each metabolic pathway with a limited number of genes. Firstly, an approach is presented which minimizes the overall melting temperature variance of selected probes for all genes of interest. Secondly, the approach is extended to include the additional constraints of covering all pathways with a limited number of genes while minimizing the overall variance. The new optimization problem is solved by a bottom-up programming approach which reduces the complexity to make it computationally feasible. The new method is exemplary applied for the selection of microarray probes in order to cover all fungal secondary metabolite gene clusters for Aspergillus terreus.
Abstract: The study examines the determinants of corporate cash holding of non-financial quoted firms in Nigeria using a sample of fifty four non-financial quoted firms listed on the Nigeria Stock Exchange for the period 1995-2009. Data were sourced from the Annual reports of the sampled firms and analyzed using Generalized Method of Moments(GMM). The study finds evidence supportive of a target adjustment model and that firms can not instantaneously adjust towards the target cash level owing to the fact that adjustment cost being costly,. Also, the result shows significant negative relationship between cash holdings and firm size, net working capital, return on asset and bank relationship and positive relationship with growth opportunities, leverage, inventories, account receivables and financial distress. Furthermore, there is no significant relationship between cash holdings and cash flow. In Nigerian setting, most of the variables that are relevant for explaining cash holdings in the Developed countries are found by this study to be relevant also in Nigeria.
Abstract: The limit load carrying capacity of functionally
graded materials (FGM) circular plates subjected to an arbitrary
rotationally symmetric loading has been computed. It is provided that
the plate material behaves rigid perfectly plastic and obeys either the
Square or the Tresca yield criterion. To this end the upper and lower
bound principles of limit analysis are employed to determine the
exact value for the limiting load. The correctness of the result are
verified and finally limiting loads for two examples namely; through
radius and through thickness FGM circular plates with simply
supported edges are calculated, respectively and moreover, the values
of critical loading factor are determined.
Abstract: The scientific achievements coming from molecular
biology depend greatly on the capability of computational
applications to analyze the laboratorial results. A comprehensive
analysis of an experiment requires typically the simultaneous study
of the obtained dataset with data that is available in several distinct
public databases. Nevertheless, developing a centralized access to
these distributed databases rises up a set of challenges such as: what
is the best integration strategy, how to solve nomenclature clashes,
how to solve database overlapping data and how to deal with huge
datasets. In this paper we present GeNS, a system that uses a simple and yet innovative approach to address several biological data integration issues. Compared with existing systems, the main
advantages of GeNS are related to its maintenance simplicity and to its coverage and scalability, in terms of number of supported
databases and data types. To support our claims we present the current use of GeNS in two concrete applications. GeNS currently contains more than 140 million of biological relations and it can be
publicly downloaded or remotely access through SOAP web services.
Abstract: A talking head system (THS) is presented to animate
the face of a speaking 3D avatar in such a way that it realistically
pronounces the given Korean text. The proposed system consists of
SAPI compliant text-to-speech (TTS) engine and MPEG-4 compliant
face animation generator. The input to the THS is a unicode text that is
to be spoken with synchronized lip shape. The TTS engine generates a
phoneme sequence with their duration and audio data. The TTS
applies the coarticulation rules to the phoneme sequence and sends a
mouth animation sequence to the face modeler. The proposed THS can
make more natural lip sync and facial expression by using the face
animation generator than those using the conventional visemes only.
The experimental results show that our system has great potential for
the implementation of talking head for Korean text.
Abstract: Permanent magnet synchronous machines are known
as a good candidate for hybrid electric vehicles due to their unique
merits. However they have two major drawbacks i.e. high cost and
small speed range. In this paper an optimal design of a permanent
magnet machine is presented. A reduction of permanent magnet
material for a constant torque and an extension in speed and torque
ranges are chosen as the optimization aims. For this purpose the
analytical model of the permanent magnet synchronous machine is
derived and the appropriate design algorithm is devised. The genetic
algorithm is then employed to optimize some machine specifications.
Finally the finite element method is used to validate the designed
machine.
Abstract: The objective of present work is to stimulate the
machining of material by electrical discharge machining (EDM) to
give effect of input parameters like discharge current (Ip), pulse on
time (Ton), pulse off time (Toff) which can bring about changes in the
output parameter, i.e. material removal rate. Experimental data was
gathered from die sinking EDM process using copper electrode and
Medium Carbon Steel (AISI 1040) as work-piece. The rules of
membership function (MF) and the degree of closeness to the
optimum value of the MMR are within the upper and lower range of
the process parameters. It was found that proposed fuzzy model is in
close agreement with the experimental results. By Intelligent, model
based design and control of EDM process parameters in this study
will help to enable dramatically decreased product and process
development cycle times.
Abstract: In recent years various types of electric vehicles
has gained again increasing attention as an environmentally
benign technology in transport. Especially for urban areas with
high local pollution this Zero-emission technology (at the point
of use) is considered to provide proper solutions. Yet, the bad
economics and the limited driving ranges are still major barriers
for a broader market penetration of battery electric vehicles
(BEV) and of fuel cell vehicles (FCV). The major result of our
analyses is that the most important precondition for a further
dissemination of BEV in urban areas are emission-free zones.
This is an instrument which allows the promotion of BEV
without providing excessive subsidies. In addition, it is
important to note that the full benefits of EV can only be
harvested if the electricity used is produced from renewable
energy sources. That is to say, it has to be ensured that the use of
BEV in urban areas is clearly linked to a green electricity
purchase model. And moreover, the introduction of a CO2-
emission-based tax system would support this requirement.
Abstract: Thermo-chemical treatment (TCT) such as pyrolysis
is getting recognized as a valid route for (i) materials and valuable
products and petrochemicals recovery; (ii) waste recycling; and (iii)
elemental characterization. Pyrolysis is also receiving renewed
attention for its operational, economical and environmental
advantages. In this study, samples of polyethylene terephthalate
(PET) and polystyrene (PS) were pyrolysed in a microthermobalance
reactor (using a thermogravimetric-TGA setup). Both
polymers were prepared and conditioned prior to experimentation.
The main objective was to determine the kinetic parameters of the
depolymerization reactions that occur within the thermal degradation
process. Overall kinetic rate constants (ko) and activation energies
(Eo) were determined using the general kinetics theory (GKT)
method previously used by a number of authors. Fitted correlations
were found and validated using the GKT, errors were within ± 5%.
This study represents a fundamental step to pave the way towards the
development of scaling relationship for the investigation of larger
scale reactors relevant to industry.
Abstract: The phase diagrams and compositions of coexisting
phases have been determined for aqueous two-phase systems
containing poly(propylene glycol) with average molecular weight of
425 and sodium citrate at various pH of 3.93, 4.44, 4.6, 4.97, 5.1,
8.22. The effect of pH on the salting-out effect of poly (propylene
glycol) by sodium citrate has been studied. It was found that, an
increasing in pH caused the expansion of two-phase region.
Increasing pH also increases the concentration of PPG in the PPGrich
phase, while the salt-rich phase will be somewhat mole diluted.
Abstract: Spectrum is a scarce commodity, and considering the spectrum scarcity faced by the wireless-based service providers led to high congestion levels. Technical inefficiencies from pooled, since all networks share a common pool of channels, exhausting the available channels will force networks to block the services. Researchers found that cognitive radio (CR) technology may resolve the spectrum scarcity. A CR is a self-configuring entity in a wireless networking that senses its environment, tracks changes, and frequently exchanges information with their networks. However, CRN facing challenges and condition become worst while tracks changes i.e. reallocation of another under-utilized channels while primary network user arrives. In this paper, channels or resource reallocation technique based on DNA-inspired computing algorithm for CRN has been proposed.
Abstract: In this paper, we present a new method for
incorporating global shift invariance in support vector machines.
Unlike other approaches which incorporate a feature extraction stage,
we first scale the image and then classify it by using the modified
support vector machines classifier. Shift invariance is achieved by
replacing dot products between patterns used by the SVM classifier
with the maximum cross-correlation value between them. Unlike the
normal approach, in which the patterns are treated as vectors, in our
approach the patterns are treated as matrices (or images). Crosscorrelation
is computed by using computationally efficient
techniques such as the fast Fourier transform. The method has been
tested on the ORL face database. The tests indicate that this method
can improve the recognition rate of an SVM classifier.
Abstract: Network-Centric Air Defense Missile Systems
(NCADMS) represents the superior development of the air defense
missile systems and has been regarded as one of the major research
issues in military domain at present. Due to lack of knowledge and
experience on NCADMS, modeling and simulation becomes an effective
approach to perform operational analysis, compared with
those equation based ones. However, the complex dynamic interactions
among entities and flexible architectures of NCADMS put forward
new requirements and challenges to the simulation framework
and models. ABS (Agent-Based Simulations) explicitly addresses
modeling behaviors of heterogeneous individuals. Agents have capability
to sense and understand things, make decisions, and act on the
environment. They can also cooperate with others dynamically to
perform the tasks assigned to them. ABS proves an effective approach
to explore the new operational characteristics emerging in
NCADMS. In this paper, based on the analysis of network-centric
architecture and new cooperative engagement strategies for
NCADMS, an agent-based simulation framework by expanding the
simulation framework in the so-called System Effectiveness Analysis
Simulation (SEAS) was designed. The simulation framework specifies
components, relationships and interactions between them, the
structure and behavior rules of an agent in NCADMS. Based on scenario
simulations, information and decision superiority and operational
advantages in NCADMS were analyzed; meanwhile some
suggestions were provided for its future development.
Abstract: This paper is concerned with the numerical minimization
of energy functionals in BV (
) (the space of bounded variation
functions) involving total variation for gray-scale 1-dimensional inpainting
problem. Applications are shown by finite element method
and discontinuous Galerkin method for total variation minimization.
We include the numerical examples which show the different recovery
image by these two methods.
Abstract: This paper introduces application of multi degree of freedom fuzzy(MDOFF) controller in permanent magnet (PM)drive system. The drive system model is developed for FO control. Simulation of the system is carried out to predict the performance at NL and under load,. The results indicate that application of MDOFF controller is effective for sensorless PM drive system.
Abstract: Fuzzy logic system (FLS) is used in this study to
predict the tractive performance in terms of traction force, and
motion resistance for an intelligent air cushion track vehicle while it
operates in the swamp peat. The system is effective to control the
intelligent air –cushion system with measuring the vehicle traction
force (TF), motion resistance (MR), cushion clearance height (CH)
and cushion pressure (CP). Ultrasonic displacement sensor, pull-in
solenoid electromagnetic switch, pressure control sensor, micro
controller, and battery pH sensor are incorporated with the Fuzzy
logic system to investigate experimentally the TF, MR, CH, and CP.
In this study, a comparison for tractive performance of an intelligent
air cushion track vehicle has been performed with the results obtained
from the predicted values of FLS and experimental actual values. The
mean relative error of actual and predicted values from the FLS
model on traction force, and total motion resistance are found as 5.58
%, and 6.78 % respectively. For all parameters, the relative error of
predicted values are found to be less than the acceptable limits. The
goodness of fit of the prediction values from the FLS model on TF,
and MR are found as 0.90, and 0.98 respectively.
Abstract: The elimination of ranitidine (a pharmaceutical
compound) has been carried out in the presence of UV-C radiation.
After some preliminary experiments, it has been experienced the no
influence of the gas nature (air or oxygen) bubbled in photolytic
experiments. From simple photolysis experiments the quantum yield
of this compound has been determined. Two photolytic
approximation has been used, the linear source emission in parallel
planes and the point source emission in spherical planes. The
quantum yield obtained was in the proximity of 0.05 mol Einstein-1
regardless of the method used. Addition of free radical promoters
(hydrogen peroxide) increases the ranitidine removal rate while the
use of photocatalysts (TiO2) negatively affects the process.
Abstract: A frequency grouping approach for multi-channel
instantaneous blind source separation (I-BSS) of convolutive
mixtures is proposed for a lower net residual inter-symbol
interference (ISI) and inter-channel interference (ICI) than the
conventional short-time Fourier transform (STFT) approach. Starting
in the time domain, STFTs are taken with overlapping windows to
convert the convolutive mixing problem into frequency domain
instantaneous mixing. Mixture samples at the same frequency but
from different STFT windows are grouped together forming unique
frequency groups.
The individual frequency group vectors are input to the I-BSS
algorithm of choice, from which the output samples are dispersed
back to their respective STFT windows. After applying the inverse
STFT, the resulting time domain signals are used to construct the
complete source estimates via the weighted overlap-add method
(WOLA). The proposed algorithm is tested for source deconvolution
given two mixtures, and simulated along with the STFT approach to
illustrate its superiority for fairly motionless sources.
Abstract: Since large power transformers are the most
expensive and strategically important components of any power
generator and transmission system, their reliability is crucially
important for the energy system operation. Also, Circuit breakers are
very important elements in the power transmission line so monitoring
the events gives a knowledgebase to determine time to the next
maintenance. This paper deals with the introduction of the
comparative method of the state estimation of transformers and
Circuit breakers using continuous monitoring of voltage, current.
This paper gives details a new method based on wavelet to apparatus
insulation monitoring. In this paper to insulation monitoring of
transformer, a new method based on wavelet transformation and
neutral point analysis is proposed. Using the EMTP tools, fault in
transformer winding and the detailed transformer winding model
were simulated. The current of neutral point of winding was analyzed
by wavelet transformation. It is shown that the neutral current of the
transformer winding has useful information about fault in insulation
of the transformer.
Abstract: Fuzzy linear programming is an application of fuzzy set theory in linear decision making problems and most of these problems are related to linear programming with fuzzy variables. A convenient method for solving these problems is based on using of auxiliary problem. In this paper a new method for solving fuzzy variable linear programming problems directly using linear ranking functions is proposed. This method uses simplex tableau which is used for solving linear programming problems in crisp environment before.