Abstract: Several embryonic cellular mechanism including cell
cycle, growth and apoptosis are regulated by phosphatidylinositol-3-
kinase (PI3K)/Akt signaling pathway. The goal of present study is to
determine the effects of annatto (Bixa orellana)-derived δ-tocotrienol
(δ-TCT) on the regulations of PI3K/Akt genes in murine morula.
Twenty four 6-8 week old (23-25g) female balb/c mice were
randomly divided into four groups (G1-G4; n=6). Those groups were
subjected to the following treatments for 7 consecutive days: G1
(control) received tocopherol stripped corn oil, G2 was given 60
mg/kg/day of δ-TCT mixture (contains 90% delta & 10% gamma
isomers), G3 was given 60 mg/kg/day of pure δ-TCT (>98% purity)
and G4 received 60 mg/kg/day α-TOC. On Day 8, females were
superovulated with 5 IU Pregnant Mare’s Serum Gonadotropin
(PMSG) for 48 hours followed with 5 IU human Chorionic
Gonadotropin (hCG) before mated with males at the ratio of 1:1.
Females were sacrificed by cervical dislocation for embryo collection
48 hours post-coitum. About fifty morulas from each group were
used in the gene expression analyses using Affymetrix QuantiGene
Plex 2.0 Assay. Present data showed a significant increase (p
Abstract: The goal of this paper is to present the diagnostic
contribution that the screening instrument, Mini-Mental State
Examination-2: Expanded Version (MMSE-2:EV), brings in
detecting the cognitive impairment or in monitoring the progress of
degenerative disorders. The diagnostic signification is underlined by
the interpretation of the MMSE-2:EV scores, resulted from the test
application to patients with mild and major neurocognitive disorders.
The cases were selected from current practice, in order to cover vast
and significant neurocognitive pathology: mild cognitive impairment,
Alzheimer’s disease, vascular dementia, mixed dementia, Parkinson’s
disease, conversion of the mild cognitive impairment into
Alzheimer’s disease. The MMSE-2:EV version was used: it was
applied one month after the initial assessment, three months after the
first reevaluation and then every six months, alternating the blue and
red forms. Correlated with age and educational level, the raw scores
were converted in T scores and then, with the mean and the standard
deviation, the z scores were calculated. The differences of raw scores
between the evaluations were analyzed from the point of view of
statistic signification, in order to establish the progression in time of
the disease. The results indicated that the psycho-diagnostic approach
for the evaluation of the cognitive impairment with MMSE-2:EV is
safe and the application interval is optimal. In clinical settings with a
large flux of patients, the application of the MMSE-2:EV is a safe
and fast psychodiagnostic solution. The clinicians can draw objective
decisions and for the patients: it does not take too much time and
energy, it does not bother them and it doesn’t force them to travel
frequently.
Abstract: A robust sequential nonparametric method is proposed
for adaptation to background noise parameters for real-time. The
distribution of background noise was modelled like to Huber
contamination mixture. The method is designed to operate as an
adaptation-unit, which is included inside a detection subsystem of an
integrated multichannel monitoring system. The proposed method
guarantees the given size of a nonasymptotic confidence set for noise
parameters. Properties of the suggested method are rigorously
proved. The proposed algorithm has been successfully tested in real
conditions of a functioning C-OTDR monitoring system, which was
designed to monitor railways.
Abstract: The MEMS pressure sensor has been introduced and
presented in this paper. The types of pressure sensor and its theory of
operation are also included. The latest MEMS technology, the
fabrication processes of pressure sensor are explored and discussed.
Besides, various device applications of pressure sensor such as tire
pressure-monitoring system, diesel particulate filter and others are
explained. Due to further miniaturization of the device nowadays, the
pressure sensor with nanotechnology (NEMS) is also reviewed. The
NEMS pressure sensor is expected to have better performance as well
as lower in its cost. It has gained an excellent popularity in many
applications.
Abstract: Live video streaming is one of the most widely used
service among end users, yet it is a big challenge for the network
operators in terms of quality. The only way to provide excellent
Quality of Experience (QoE) to the end users is continuous
monitoring of live video streaming. For this purpose, there are several
objective algorithms available that monitor the quality of the video in
a live stream. Subjective tests play a very important role in fine
tuning the results of objective algorithms. As human perception is
considered to be the most reliable source for assessing the quality of a
video stream subjective tests are conducted in order to develop more
reliable objective algorithms. Temporal impairments in a live video
stream can have a negative impact on the end users. In this paper we
have conducted subjective evaluation tests on a set of video
sequences containing temporal impairment known as frame freezing.
Frame Freezing is considered as a transmission error as well as a
hardware error which can result in loss of video frames on the
reception side of a transmission system. In our subjective tests, we
have performed tests on videos that contain a single freezing event
and also for videos that contain multiple freezing events. We have
recorded our subjective test results for all the videos in order to give a
comparison on the available No Reference (NR) objective
algorithms. Finally, we have shown the performance of no reference
algorithms used for objective evaluation of videos and suggested the
algorithm that works better. The outcome of this study shows the
importance of QoE and its effect on human perception. The results
for the subjective evaluation can serve the purpose for validating
objective algorithms.
Abstract: This study compares the intensity of game load among
player positions and between the 1st and the 2nd half of the games.
Two guards, three forwards, and three centers (female basketball
players) participated in this study. The heart rate (HR) and its
development were monitored during two competitive games.
Statistically insignificant differences in the intensity of game load
were recorded between guards, forwards, and centers below and
above 85% of the maximal heart rate (HRmax) and in the mean HR as
% of HRmax (87.81±3.79%, 87.02±4.37%, and 88.76±3.54%,
respectively). Moreover, when the 1st and the 2nd half of the games
were compared in the mean HR (87.89±4.18% vs. 88.14±3.63% of
HRmax), no statistical significance was recorded. This information can
be useful for coaching staff, to manage and to precisely plan the
training process.
Abstract: This paper presents an approach of on-line control of
the state of technosphere and environment objects based on the
integration of Data Warehouse, OLAP and Expert systems
technologies. It looks at the structure and content of data warehouse
that provides consolidation and storage of monitoring data. There is a
description of OLAP-models that provide a multidimensional
analysis of monitoring data and dynamic analysis of principal
parameters of controlled objects. The authors suggest some criteria of
emergency risk assessment using expert knowledge about danger
levels. It is demonstrated now some of the proposed solutions could
be adopted in territorial decision making support systems.
Operational control allows authorities to detect threat, prevent natural
and anthropogenic emergencies and ensure a comprehensive safety of
territory.
Abstract: Transparent nickel doped cobalt sulfide was fabricated
on a SnO2:F electrode and tested as an efficient electrocatalyst and as
an alternative to the expensive platinum counter electrode. In order to
investigate how this electrode could affect the electrical
characteristics of a dye-sensitized solar cell, we manufactured cells
with the same TiO2 photoanode sensitized with dye (N719) and
employing the same quasi-solid electrolyte, altering only the counter
electrode used. The cells were electrically and electrochemically
characterized and it was observed that the ones with the Ni doped
CoS2 outperformed the efficiency of the cells with the Pt counter
electrode (3.76% and 3.44% respectively). Particularly, the higher
efficiency of the cells with the Ni doped CoS2 counter electrode (CE)
is mainly because of the enhanced photocurrent density which is
attributed to the enhanced electrocatalytic ability of the CE and the
low charge transfer resistance at the CE/electrolyte interface.
Abstract: The purpose of the paper is to address the strategic
risk issues surrounding Hindi film distribution in Mumbai for a film
distributor, who acts as an entrepreneur when launching a product
(movie) in the market (film territory).The paper undertakes a
fundamental review of films and risk in the Hindi film industry and
applies Grounded Theory technique to understand the complex
phenomena of risk taking behavior of the film distributors (both
independent and studios) in Mumbai. Rich in-depth interviews with
distributors are coded to develop core categories through constant
comparison leading to conceptualization of the phenomena of
interest. This paper is a first-of-its-kind-attempt to understand risk
behavior of a distributor, which is akin to entrepreneurial risk
behavior under conditions of uncertainty.
Abstract: Superabsorbent polymers received much attention and
are used in many fields because of their superior characters to
traditional absorbents, e.g., sponge and cotton. So, it is very
important but challenging to prepare highly and fast-swelling
superabsorbents. A reliable, efficient and low-cost technique for
removing heavy metal ions from wastewater is the adsorption using
bio-adsorbents obtained from biological materials, such as
polysaccharides-based hydrogels superabsorbents. In this study, novel multi-functional superabsorbent composites
type semi-interpenetrating polymer networks (Semi-IPNs) were
prepared via graft polymerization of acrylamide onto chitosan
backbone in presence of gelatin, CTS-g-PAAm/Ge, using potassium
persulfate and N,N’-methylene bisacrylamide as initiator and
crosslinker, respectively. These hydrogels were also partially
hydrolyzed to achieve superabsorbents with ampholytic properties
and uppermost swelling capacity. The formation of the grafted
network was evidenced by Fourier Transform Infrared Spectroscopy
(ATR-FTIR) and Thermogravimetric Analysis (TGA). The porous
structures were observed by Scanning Electron Microscope (SEM).
From TGA analysis, it was concluded that the incorporation of the Ge
in the CTS-g-PAAm network has marginally affected its thermal
stability. The effect of gelatin content on the swelling capacities of
these superabsorbent composites was examined in various media
(distilled water, saline and pH-solutions). The water absorbency was
enhanced by adding Ge in the network, where the optimum value was
reached at 2 wt. % of Ge. Their hydrolysis has not only greatly
optimized their absorption capacity but also improved the swelling
kinetic.These materials have also showed reswelling ability. We
believe that these super-absorbing materials would be very effective
for the adsorption of harmful metal ions from wastewater.
Abstract: Aurèsregion is one of the arid and semi-arid areas that
have suffered climate crises and overexploitation of natural resources
they have led to significant land degradation. The use of remote sensing data allowed us to analyze the land and
its spatiotemporal changes in the Aurès between 1987 and 2013, for
this work, we adopted a method of analysis based on the exploitation
of the images satellite Landsat TM 1987 and Landsat OLI 2013, from
the supervised classification likelihood coupled with field surveys of
the mission of May and September of 2013. Using ENVI EX software by the superposition of the ground cover
maps from 1987 and 2013, one can extract a spatial map change of
different land cover units. The results show that between 1987 and
2013 vegetation has suffered negative changes are the significant
degradation of forests and steppe rangelands, and sandy soils and
bare land recorded a considerable increase. The spatial change map land cover units between 1987 and 2013
allows us to understand the extensive or regressive orientation of
vegetation and soil, this map shows that dense forests give his place
to clear forests and steppe vegetation develops from a degraded forest
vegetation and bare, sandy soils earn big steppe surfaces that explain
its remarkable extension.
The analysis of remote sensing data highlights the profound
changes in our environment over time and quantitative monitoring of
the risk of desertification.
Abstract: This paper presents a state-of-the-art survey of the
operations research models developed for internal audit planning.
Two alternative approaches have been followed in the literature for
audit planning: (1) identifying the optimal audit frequency; and (2)
determining the optimal audit resource allocation. The first approach
identifies the elapsed time between two successive audits, which can
be presented as the optimal number of audits in a given planning
horizon, or the optimal number of transactions after which an audit
should be performed. It also includes the optimal audit schedule. The
second approach determines the optimal allocation of audit frequency
among all auditable units in the firm. In our review, we discuss both
the deterministic and probabilistic models developed for audit
planning. In addition, game theory models are reviewed to find the
optimal auditing strategy based on the interactions between the
auditors and the clients.
Abstract: This paper describes a novel sensor device, a pressure
pulse wave meter, which uses a bidirectional condenser microphone.
The microphone work as a microphone as well as a sensor with high
gain over a wide frequency range; they are also highly reliable and
economic. Currently aging is becoming a serious social issue in Japan causing
increased medical expenses in the country. Hence, it is important for
elderly citizens to check health condition at home, and to care the
health conditions through daily monitoring. Given this circumstances,
we developed a novel pressure pulse wave meter based on a
bidirectional condenser microphone: this device is used as a measuring
instrument of health conditions.
Abstract: Despite the advances made in various new
technologies, application of these technologies for agriculture still
remains a formidable task, as it involves integration of diverse
domains for monitoring the different process involved in agricultural
management. Advances in ambient intelligence technology represents
one of the most powerful technology for increasing the yield of
agricultural crops and to mitigate the impact of water scarcity,
climatic change and methods for managing pests, weeds and diseases.
This paper proposes a GPS-assisted, machine to machine solutions
that combine information collected by multiple sensors for the
automated management of paddy crops. To maintain the economic
viability of paddy cultivation, the various techniques used in
agriculture are discussed and a novel system which uses ambient
intelligence technique is proposed in this paper. The ambient
intelligence based agricultural system gives a great scope.
Abstract: Present work deals with the possible use of fertigation
in agriculture and its impact on the availability of mineral nitrogen
(Nmin) in topsoil and subsoil horizons. The aim of the present study is
to demonstrate the effect of the organic matter presence in fertigation
on microbial transformation and availability of mineral nitrogen
forms. The main investigation reason is the potential use of pretreated
waste water, as a source of organic carbon (Corg) and residual
nutrients (Nmin) for fertigation. Laboratory experiment has been
conducted to demonstrate the effect of the arable land fertilization
method on the Nmin availability in different depths of the soil with
the usage of model experimental containers filled with soil from
topsoil and podsoil horizons that were taken from the precise area.
Tufted hairgrass (Deschampsia caespitosa) has been chosen as a
model plant. The water source protection zone Brezova nad Svitavou
has been a research area where significant underground reservoirs of
drinking water of the highest quality are located. From the second
half of the last century local sources of drinking water show
nitrogenous compounds increase that get here almost only from
arable lands. Therefore, an attention of the following text focuses on
the fate of mineral nitrogen in the complex plant-soil. Research
results show that the fertigation application with Corg in a
combination with mineral fertilizer can reduce the amount of Nmin
leached from topsoil horizon of agricultural soils. In addition, some
plants biomass production reduces may occur.
Abstract: This paper is focused on the reference current
calculation in the compensation mode of the active DC traction
substations. The so-called p-q theory of the instantaneous reactive
power is used as theoretical foundation. The compensation goal of
total compensation is taken into consideration for the operation under
both sinusoidal and nonsinusoidal voltage conditions, through the
two objectives of unity power factor and perfect harmonic
cancelation. Four blocks of reference current generation implement
the conceived algorithms and they are included in a specific Simulink
library, which is useful in a DSP dSPACE-based platform working
under Matlab/Simulink. The simulation results validate the
correctness of the implementation and fulfillment of the
compensation tasks.
Abstract: In light of the technological development and its
introduction into the field of education, an online course was
designed in parallel to the 'conventional' course for teaching the
''Qualitative Research Methods''. This course aimed to characterize
learning-teaching processes in a 'Qualitative Research Methods'
course studied in two different frameworks. Moreover, its objective
was to explore the difference between the culture of a physical
learning environment and that of online learning. The research
monitored four learner groups, a total of 72 students, for two years,
two groups from the two course frameworks each year. The courses
were obligatory for M.Ed. students at an academic college of
education and were given by one female-lecturer. The research was
conducted in the qualitative method as a case study in order to attain
insights about occurrences in the actual contexts and sites in which
they transpire. The research tools were open-ended questionnaire and
reflections in the form of vignettes (meaningful short pictures) to all
students as well as an interview with the lecturer. The tools facilitated
not only triangulation but also collecting data consisting of voices
and pictures of teaching and learning. The most prominent findings
are: differences between the two courses in the change features of the
learning environment culture for the acquisition of contents and
qualitative research tools. They were manifested by teaching
methods, illustration aids, lecturer's profile and students' profile.
Abstract: This study suggests the estimation method of stress
distribution for the beam structures based on TLS (Terrestrial Laser
Scanning). The main components of method are the creation of the
lattices of raw data from TLS to satisfy the suitable condition and
application of CSSI (Cubic Smoothing Spline Interpolation) for
estimating stress distribution. Estimation of stress distribution for the
structural member or the whole structure is one of the important
factors for safety evaluation of the structure. Existing sensors which
include ESG (Electric strain gauge) and LVDT (Linear Variable
Differential Transformer) can be categorized as contact type sensor
which should be installed on the structural members and also there are
various limitations such as the need of separate space where the
network cables are installed and the difficulty of access for sensor
installation in real buildings. To overcome these problems inherent in
the contact type sensors, TLS system of LiDAR (light detection and
ranging), which can measure the displacement of a target in a long
range without the influence of surrounding environment and also get
the whole shape of the structure, has been applied to the field of
structural health monitoring. The important characteristic of TLS
measuring is a formation of point clouds which has many points
including the local coordinate. Point clouds are not linear distribution
but dispersed shape. Thus, to analyze point clouds, the interpolation is
needed vitally. Through formation of averaged lattices and CSSI for
the raw data, the method which can estimate the displacement of
simple beam was developed. Also, the developed method can be
extended to calculate the strain and finally applicable to estimate a
stress distribution of a structural member. To verify the validity of the
method, the loading test on a simple beam was conducted and TLS
measured it. Through a comparison of the estimated stress and
reference stress, the validity of the method is confirmed.
Abstract: The paper provides a comprehensive analysis of the
sustainable development in the Belgrade Metropolitan Region - BMA
(level NUTS 2) preliminary evaluating the three chosen components:
1) economic growth and developmental changes; 2) competitiveness;
and 3) territorial concentration and industrial specialization. First, we
identified the main results of development changes and economic
growth by applying Shift-share analysis on the metropolitan level.
Second, the empirical evaluation of competitiveness in the BMA is
based on the analysis of absolute and relative values of eight
indicators by Spider method. Paper shows that the consideration of
the national share, industrial mix and metropolitan/regional share in
total Shift share of the BMA, as well as economic/functional
specialization of the BMA indicate very strong process of
deindustrialization. Allocative component of the BMA economic
growth has positive value, reflecting the above-average sector
productivity compared to the national average. Third, the important
positive role of metropolitan/regional component in decomposition of
the BMA economic growth is highlighted as one of the key results.
Finally, comparative analysis of the industrial territorial
concentration in the BMA in relation to Serbia is based on location
quotient (LQ) or Balassa index as a valid measure. The results
indicate absolute and relative differences in decrease of industry
territorial concentration as well as inefficiency of utilizing territorial
capital in the BMA. Results are important for the increase of regional
competitiveness and territorial distribution in this area as well as for
improvement of sustainable metropolitan and sector policies,
planning and governance on this level.
Abstract: Waste Load Allocation (WLA) strategies usually
intend to find economic policies for water resource management.
Water quality trading (WQT) is an approach that uses discharge
permit market to reduce total environmental protection costs. This
primarily requires assigning discharge limits known as total
maximum daily loads (TMDLs). These are determined by monitoring
organizations with respect to the receiving water quality and
remediation capabilities. The purpose of this study is to compare two
approaches of TMDL assignment for WQT policy in small catchment
area of Haraz River, in north of Iran. At first, TMDLs are assigned
uniformly for the whole point sources to keep the concentrations of
BOD and dissolved oxygen (DO) at the standard level at checkpoint
(terminus point). This was simply simulated and controlled by
Qual2kw software. In the second scenario, TMDLs are assigned
using multi objective particle swarm optimization (MOPSO) method
in which the environmental violation at river basin and total treatment
costs are minimized simultaneously. In both scenarios, the equity
index and the WLA based on trading discharge permits (TDP) are
calculated. The comparative results showed that using economically
optimized TMDLs (2nd scenario) has slightly more cost savings rather
than uniform TMDL approach (1st scenario). The former annually
costs about 1 M$ while the latter is 1.15 M$. WQT can decrease
these annual costs to 0.9 and 1.1 M$, respectively. In other word,
these approaches may save 35 and 45% economically in comparison
with command and control policy. It means that using multi objective
decision support systems (DSS) may find more economical WLA,
however its outcome is not necessarily significant in comparison with
uniform TMDLs. This may be due to the similar impact factors of
dischargers in small catchments. Conversely, using uniform TMDLs
for WQT brings more equity that makes stakeholders not feel that
much envious of difference between TMDL and WQT allocation. In
addition, for this case, determination of TMDLs uniformly would be
much easier for monitoring. Consequently, uniform TMDL for TDP
market is recommended as a sustainable approach. However,
economical TMDLs can be used for larger watersheds.