Abstract: The article represents the results of clinical researches
of composite herbal medicinal product based on essential oils of
Sedum plants growing in Kazakhstan in commercial reserves at the
territory of Kazakhstan. The results of comparative analysis are
represented in obstetric-gynecologic practice during combined
therapy for postnatal complications, inflammatory infiltrates in the
area of surgical wounds including wounds after caesarean section.
Abstract: The article represents the results of research of
antitumor activity of different structural types of plant flavonoids
extracted by authors from Polygonum L. plants in commercial
reserves at the territory of the Republic of Kazakhstan. For the first
time ever the results comparative research of antitumor activity of
plant flavonoids of different structural groups and their synthetic
derivatives have been represented. The results of determination of
toxicity of flavonoids in single parenteral infusion conditions have
been represented. Experimental substantiation of possible
mechanisms of antiproliferative and cytotoxic action of flavonoids
has been suggested. The perspectives of usage of plant flavonoids as
medications and creation of effective dosage forms of antitumor
medicines on their basis have been substantiated.
Abstract: An adaptive nonparametric method is proposed for
stable real-time detection of seismoacoustic sources in multichannel
C-OTDR systems with a significant number of channels. This
method guarantees given upper boundaries for probabilities of Type I
and Type II errors. Properties of the proposed method are rigorously
proved. The results of practical applications of the proposed method
in a real C-OTDR-system are presented in this report.
Abstract: Agro-industry is one of major industries that have
strong impacts on national economic incomes, growth, stability, and
sustainable development. Moreover, this industry also has strong
influences on social, cultural and political issues. Furthermore, this
industry, as producing primary and secondary products, is facing
challenges from such diverse factors such as demand inconsistency,
intense international competition, technological advancements and
new competitors. In order to maintain and to improve industry’s
competitiveness in both domestics and international markets, science
and technology are key factors. Besides hard sciences and
technologies, modern industrial engineering concepts such as Just in
Time (JIT) Total Quality Management (TQM), Quick Response
(QR), Supply Chain Management (SCM) and Lean can be very
effective to support to increase efficiency and effectiveness of these
agricultural products on world stage. Onion is one of Thailand’s
major export products which bring back national incomes. But, it is
also facing challenges in many ways. This paper focused its interests
in onion packing process and its related activities such as storage and
shipment from one of major packing plant and storage in Mae Wang
District, Chiang Mai, Thailand, by applying Toyota Production
System (TPS) or Lean concepts, to improve process capability
throughout the entire packing and distribution process which will be
profitable for the whole onion supply chain. And it will be beneficial
to other related agricultural products in Thailand and other ASEAN
countries.
Abstract: The potential neuroprotective effect of Phyllantus
nuriri against Fe2+ and sodium nitroprusside (SNP) induced oxidative
stress in mitochondria of rats brain was evaluated. Cellular viability
was assessed by MTT reduction, reactive oxygen species (ROS)
generation was measured using the probe 2,7-dichlorofluoresce
indiacetate (DCFH-DA). Glutathione content was measured using
dithionitrobenzoic acid (DTNB). Fe2+ (10μM) and SNP (5μM)
significantly decreased mitochondrial activity, assessed by MTT
reduction assay, in a dose-dependent manner, this occurred in parallel
with increased glutathione oxidation, ROS production and lipid
peroxidation end-products (thiobarbituric acid reactive substances,
TBARS). The co-incubation with methanolic extract of Phyllantus
nuriri (10-200 μg/ml) reduced the disruption of mitochondrial
activity, gluthathione oxidation, ROS production as well as the
increase in TBARS levels caused by both Fe2+ and SNP in a dose
dependent manner. HPLC analysis of the extract revealed the
presence of gallic acid (20.540.01), caffeic acid (7.930.02), rutin
(25.310.05), quercetin (31.280.03) and kaemferol (14.360.01).
This result suggests that these phytochemicals account for the
protective actions of P. niruri against Fe2+ and SNP -induced
oxidative stress. Our results show that P. nuriri consist important
bioactive molecules in the search for an improved therapy against the
deleterious effects of Fe2+, an intrinsic producer of reactive oxygen
species (ROS), that leads to neuronal oxidative stress and
neurodegeneration.
Abstract: PhilSHORE is a multi-site, multi-device and multicriteria
decision support tool designed to support the development of
tidal current energy in the Philippines. Its platform is based on
Geographic Information Systems (GIS) which allows for the
collection, storage, processing, analyses and display of geospatial
data. Combining GIS tools with open source web development
applications, PhilSHORE becomes a webGIS-based marine spatial
planning tool. To date, PhilSHORE displays output maps and graphs
of power and energy density, site suitability and site-device analysis.
It enables stakeholders and the public easy access to the results of
tidal current energy resource assessments and site suitability
analyses. Results of the initial development show that PhilSHORE is
a promising decision support tool for ORE project developments.
Abstract: Coal is an important non-renewable energy source of
and can be associated with radioactive elements. In Figueira city,
Paraná state, Brazil, it was recorded high uranium activity near the
coal mine that supplies a local thermoelectric power plant. In this
context, the radon activity (Rn-222, produced by the Ra-226 decay in
the U-238 natural series) was evaluated in groundwater, river water
and effluents produced from the acid mine drainage in the coal reject
dumps. The samples were collected in August 2013 and in February
2014 and analyzed at LABIDRO (Laboratory of Isotope and
Hydrochemistry), UNESP, Rio Claro city, Brazil, using an alpha
spectrometer (AlphaGuard) adjusted to evaluate the mean radon
activity concentration in five cycles of 10 minutes. No radon activity
concentration above 100 Bq.L-1, which was a previous critic value
established by the World Health Organization. The average radon
activity concentration in groundwater was higher than in surface
water and in effluent samples, possibly due to the accumulation of
uranium and radium in the aquifer layers that favors the radon
trapping. The lower value in the river waters can indicate dilution and
the intermediate value in the effluents may indicate radon absorption
in the coal particles of the reject dumps. The results also indicate that
the radon activities in the effluents increase with the sample
acidification, possibly due to the higher radium leaching and the
subsequent radon transport to the drainage flow. The water samples
of Laranjinha River and Ribeirão das Pedras stream, which,
respectively, supply Figueira city and receive the mining effluent,
exhibited higher pH values upstream the mine, reflecting the acid
mine drainage discharge. The radionuclides transport indicates the
importance of monitoring their activity concentration in natural
waters due to the risks that the radioactivity can represent to human
health.
Abstract: The Aptima® HIV-1 Quant Dx Assay is a fully
automated assay on the Panther system. It is based on Transcription-
Mediated Amplification and real time detection technologies. This
assay is intended for monitoring HIV-1 viral load in plasma
specimens and for the detection of HIV-1 in plasma and serum
specimens.
Nine-hundred and seventy nine specimens selected at random
from routine testing at St Thomas’ Hospital, London were
anonymised and used to compare the performance of the Aptima
HIV-1 Quant Dx assay and Roche COBAS® AmpliPrep/COBAS®
TaqMan® HIV-1 Test, v2.0. Two-hundred and thirty four specimens
gave quantitative HIV-1 viral load results in both assays. The
quantitative results reported by the Aptima Assay were comparable to
those reported by the Roche COBAS AmpliPrep/COBAS TaqMan
HIV-1 Test, v2.0 with a linear regression slope of 1.04 and an
intercept on -0.097.
The Aptima assay detected HIV-1 in more samples than the
COBAS assay. This was not due to lack of specificity of the Aptima
assay because this assay gave 99.83% specificity on testing plasma
specimens from 600 HIV-1 negative individuals. To understand the
reason for this higher detection rate a side-by-side comparison of low
level panels made from the HIV-1 3rd international standard
(NIBSC10/152) and clinical samples of various subtypes were tested
in both assays. The Aptima assay was more sensitive than the
COBAS assay.
The good sensitivity, specificity and agreement with other
commercial assays make the HIV-1 Quant Dx Assay appropriate for
both viral load monitoring and detection of HIV-1 infections.
Abstract: Chrome tannery wastewater causes serious environmental hazard due to its high pollution potential. As a result, rigorous treatment is necessary for abatement of pollution from this type of wastewater. There are many research studies on chrome tannery wastewater treatment in the field of physical, chemical, and biological methods. In general, biological treatment process is found ineffective for direct application because of adverse effects by toxic chromium, sulphide, chloride etc. However, biological methods were employed mainly for a few sub processes generating significant amount of organic matter and without chromium, chlorides etc. In this context the present paper reviews the characteristics feature and pollution potential of wastewater generated from chrome tannery units and treatment of the same. The different biological processes used earlier and their chronological development for treatment of the chrome tannery wastewater are thoroughly reviewed in this paper. In this regard, the scope of hybrid bioreactor - an advanced technology option has also been explored, as this kind of treatment is well suited for the wastewater having inhibitory substances.
Abstract: The article deals with the tool in Matlab GUI form
that is designed to analyse a mechatronic system sensitivity and
tolerance. In the analysed mechatronic system, a torque is transferred
from the drive to the load through a coupling containing flexible
elements. Different methods of control system design are used. The
classic form of the feedback control is proposed using Naslin method,
modulus optimum criterion and inverse dynamics method. The
cascade form of the control is proposed based on combination of
modulus optimum criterion and symmetric optimum criterion. The
sensitivity is analysed on the basis of absolute and relative sensitivity
of system function to the change of chosen parameter value of the
mechatronic system, as well as the control subsystem. The tolerance
is analysed in the form of determining the range of allowed relative
changes of selected system parameters in the field of system stability.
The tool allows to analyse an influence of torsion stiffness, torsion
damping, inertia moments of the motor and the load and controller(s)
parameters. The sensitivity and tolerance are monitored in terms of
the impact of parameter change on the response in the form of system
step response and system frequency-response logarithmic
characteristics. The Symbolic Math Toolbox for expression of the
final shape of analysed system functions was used. The sensitivity
and tolerance are graphically represented as 2D graph of sensitivity
or tolerance of the system function and 3D/2D static/interactive graph
of step/frequency response.
Abstract: The objective of the article was to identify the impacts of gamification on customers' behaviour. The most important applications of games in marketing and mechanisms of gamification are presented in the article. A detailed analysis of the influence of gamification on customers using two brands, Foursquare and Nike, was also presented. Research studies using auditory survey methods were carried out among 176 young respondents, who are potential targets of gamification. The studies confirmed a huge participation of young people in customer loyalty programs with relatively low participation in other gamificationbased marketing activities. The research findings clearly indicate that gamification mechanisms are the most attractive.
Abstract: Moving into a new era of healthcare, new tools and
devices are developed to extend and improve health services, such as
remote patient monitoring and risk prevention. In this concept,
Internet of Things (IoT) and Cloud Computing present great
advantages by providing remote and efficient services, as well as
cooperation between patients, clinicians, researchers and other health
professionals. This paper focuses on patients suffering from bipolar
disorder, a brain disorder that belongs to a group of conditions
called affective disorders, which is characterized by great mood
swings. We exploit the advantages of Semantic Web and Cloud
Technologies to develop a patient monitoring system to support
clinicians. Based on intelligently filtering of evidence-knowledge and
individual-specific information we aim to provide treatment
notifications and recommended function tests at appropriate times or
concluding into alerts for serious mood changes and patient’s nonresponse
to treatment. We propose an architecture as the back-end
part of a cloud platform for IoT, intertwining intelligence devices
with patients’ daily routine and clinicians’ support.
Abstract: This paper presents the design and fabrication of an
optical window for an optical modulator toward image sensing
applications. An optical window consists of micrometer-order SiO2
capillaries (porous solid) that can modulate transmission light
intensity by moving the liquid in and out of porous solid. A high
optical transmittance of the optical window can be achieved due to
refractive index matching when the liquid is penetrated into the
porous solid. Otherwise, its light transmittance is lower because of
light reflection and scattering by air holes and capillary walls. Silicon
capillaries fabricated by deep reactive ion etching (DRIE) process are
completely oxidized to form the SiO2 capillaries. Therefore, high
aspect ratio SiO2 capillaries can be achieved based on silicon
capillaries formed by DRIE technique. Large compressive stress of
the oxide causes bending of the capillary structure, which is reduced
by optimizing the design of device structure. The large stress of the
optical window can be released via thin supporting beams. A 7.2 mm
x 9.6 mm optical window area toward a fully integrated with the
image sensor format is successfully fabricated and its optical
transmittance is evaluated with and without inserting liquids (ethanol
and matching oil). The achieved modulation range is approximately
20% to 35% with and without liquid penetration in visible region
(wavelength range from 450 nm to 650 nm).
Abstract: The quality and condition of perishable products
delivered to the market and their subsequent selling prices are
directly affected by the care taken during harvesting and handling.
Mechanical injury, in fact, occurs at all stages, from pre-harvest
operations through post-harvest handling, packing and transport to
the market. The main implications of this damage are the reduction of
the product’s quality and economical losses related to the shelf life
diminution. For most perishable products, the shelf life is relatively
short and it is typically dictated by microbial growth related to the
application of dynamic and static loads during transportation. This
paper presents the correlation between vibration levels and
microbiological growth on strawberries and woodland strawberries
and detects the presence of volatile organic compounds (VOC) in
order to develop an intelligent logistic unit capable of monitoring
VOCs using a specific sensor system. Fresh fruits were exposed to
vibrations by means of a vibrating table in a temperature-controlled
environment. Microbiological analyses were conducted on samples,
taken at different positions along the column of the crates. The values
obtained were compared with control samples not exposed to
vibrations and the results show that different positions along the
column influence the development of bacteria, yeasts and filamentous
fungi.
Abstract: The paper presents an innovative networked radar
system for detection of obstacles in a railway level crossing scenario.
This Monitoring System (MS) is able to detect moving or still
obstacles within the railway level crossing area automatically,
avoiding the need of human presence for surveillance. The MS is also
connected to the National Railway Information and Signaling System
to communicate in real-time the level crossing status. The
architecture is compliant with the highest Safety Integrity Level
(SIL4) of the CENELEC standard. The number of radar sensors used
is configurable at set-up time and depends on how large the level
crossing area can be. At least two sensors are expected and up four
can be used for larger areas. The whole processing chain that
elaborates the output sensor signals, as well as the communication
interface, is fully-digital, was designed in VHDL code and
implemented onto a Xilinx Virtex 6.
Abstract: This article discusses event monitoring options for
heterogeneous event sources as they are given in nowadays
heterogeneous distributed information systems. It follows the central
assumption, that a fully generic event monitoring solution cannot
provide complete support for event monitoring; instead, event source
specific semantics such as certain event types or support for certain
event monitoring techniques have to be taken into account.
Following from this, the core result of the work presented here is
the extension of a configurable event monitoring (Web) service for a
variety of event sources. A service approach allows us to trade
genericity for the exploitation of source specific characteristics. It
thus delivers results for the areas of SOA, Web services, CEP and
EDA.
Abstract: This paper presents development results of the method
of seismoacoustic activity monitoring based on usage vibrosensitive
properties of optical fibers. Analysis of Rayleigh backscattering
radiation parameters changes, which take place due to microscopic
seismoacoustic impacts on the optical fiber, allows to determine
seismoacoustic emission sources positions and to identify their types.
Results of using this approach are successful for complex monitoring
of railways.
Abstract: In the past researchers have questioned the
effectiveness of ethics training in higher education. Also, there are
observations that support the view that ethical behaviour (range of
actions)/ethical decision making models used in the past make use of
vignettes to explain ethical behaviour. The understanding remains in
the perspective that these vignettes play a limited role in determining
individual intentions and not actions. Some authors have also agreed
that there are possibilities of differences in one’s intentions and
actions. This paper makes an attempt to fill those gaps by evaluating
real actions rather than intentions. In a way this study suggests the
use of an experiential methodology to explore Berlo’s model of
communication as an action along with orchestration of various
principles. To this endeavor, an attempt was made to use
conversational analysis in the pursuance of evaluating ethical
decision making behaviour among students and middle level
managers. The process was repeated six times with the set of an
average of 15 participants. Similarities have been observed in the
behaviour of students and middle level managers that calls for
understanding that both the groups of individuals have no cognizance
of their actual actions. The deliberations derived out of conversation
were taken a step forward for meta-ethical evaluations to portray a
clear picture of ethical behaviour among participants. This study
provides insights for understanding demonstrated unconscious human
behaviour which may fortuitously be termed both ethical and
unethical.
Abstract: This paper introduces an original method for
guaranteed estimation of the accuracy for an ensemble of Lipschitz
classifiers. The solution was obtained as a finite closed set of
alternative hypotheses, which contains an object of classification with
probability of not less than the specified value. Thus, the
classification is represented by a set of hypothetical classes. In this
case, the smaller the cardinality of the discrete set of hypothetical
classes is, the higher is the classification accuracy. Experiments have
shown that if cardinality of the classifiers ensemble is increased then
the cardinality of this set of hypothetical classes is reduced. The
problem of the guaranteed estimation of the accuracy for an ensemble
of Lipschitz classifiers is relevant in multichannel classification of
target events in C-OTDR monitoring systems. Results of suggested
approach practical usage to accuracy control in C-OTDR monitoring
systems are present.
Abstract: Corrosion of concrete sewer pipes induced by sulfuric
acid is an acknowledged problem and a ticking time-bomb to sewer
operators. Whilst the chemical reaction of the corrosion process is
well-understood, the indirect roles of other parameters in the
corrosion process which are found in sewer environment are not
highly reflected on. This paper reports on a field studies undertaken
in Austria and United Kingdom, where the parameters of
temperature, pH, H2S and CO2 were monitored over a period of time.
The study establishes that (i) effluent temperature and pH have
similar daily pattern and peak times, when examined in minutes
scale; (ii) H2S and CO2 have an identical hourly pattern; (iii) H2S
instant or shifted relation to effluent temperature is governed by the
root mean square value of CO2.