Abstract: The state of the art in instructional design for
computer-assisted learning has been strongly influenced by advances
in information technology, Internet and Web-based systems. The
emphasis of educational systems has shifted from training to
learning. The course delivered has also been changed from large
inflexible content to sequential small chunks of learning objects. The
concepts of learning objects together with the advanced technologies
of Web and communications support the reusability, interoperability,
and accessibility design criteria currently exploited by most learning
systems. These concepts enable just-in-time learning. We propose to
extend theses design criteria further to include the learnability
concept that will help adapting content to the needs of learners. The
learnability concept offers a better personalization leading to the
creation and delivery of course content more appropriate to
performance and interest of each learner. In this paper we present a
new framework of learning environments containing knowledge
discovery as a tool to automatically learn patterns of learning
behavior from learners' profiles and history.
Abstract: In this paper an average number of re-handlings
analysis is proposed to solve the problem of finding bays
configuration in small container terminal in Gliwice, Poland.
Rehandlings in this terminal can be performed only by reachstackers.
The goal of the heuristic is to plan the reachstacter moves in the
terminal, assuming that the target containers are reached and the
number of re-handings is minimized. The real situation requires also
to take into account the model of the problem environment
uncertainty caused by the fact that many containers are not delivered
to the terminal on time, or can not be sent on scheduled time. To
enable this, the heuristic uses some assumptions to simplify problem
analysis.
Abstract: Housebuilders in England have been the target of numerous government policies in recent years promoting increased productivity and affordability. As a result, the housebuilding industry is currently faced with objectives to improve the affordability and sustainability of new homes whilst also increasing production rates to 240,000 per year by 2016.Yet amidst a faltering economic climate, the UK Government is forging ahead with the 'Code for Sustainable Homes', which includes stringent sustainable standards for all new homes and sets ambitious targets for the housebuilding industry, the culmination of which is the production of zero carbon homes by 2016.Great uncertainty exists amongst housebuilders as to the costs, benefits and risks of building zero carbon homes. This paper examines the key barriers to zero carbon homes from housebuilders- perspective. A comprehensive opinion on the challenges to deliver zero carbon homes is gathered through a questionnaire survey issued to the major housing developers in England. The study found that a number of cultural, legislative, and financial barriers stand in the way of the widespread construction of zero carbon homes. The study concludes with several recommendations to both the Government and the housebuilding industry to address the barriers that hinder a successful delivery of zero carbon homes in England.
Abstract: pH-sensitive drug targeting using nanoparticles for
cancer chemotherapy have been spotlighted in recent decades. Graft
copolymer composed of poly (L-histidine) (PHS) and dextran
(DexPHS) was synthesized and pH-sensitive nanoparticles were
fabricated for pH-responsive drug delivery of doxorubicin (DOX).
Nanoparticles of DexPHS showed pH-sensitive changes in particle
sizes and drug release behavior, i.e. particle sizes and drug release rate
were increased at acidic pH, indicating that DexPHS nanoparticles
have pH-sensitive drug delivery potentials. Antitumor activity of
DOX-incorporated DexPHS nanoparticles were studied using CT26
colorectal carcinoma cells. Results indicated that fluorescence
intensity was higher at acidic pH than basic pH. These results
indicated that DexPHS nanoparticles have pH-responsive drug
targeting.
Abstract: Non-viral gene carriers composed of biodegradable
polymers or lipids have been considered as a safer alternative for gene
carriers over viral vectors. We have developed multi-functional
nano-micelles for both drug and gene delivery application.
Polyethyleneimine (PEI) was modified by grafting stearic acid (SA)
and formulated to polymeric micelles (PEI-SA) with positive surface
charge for gene and drug delivery. Our results showed that PEI-SA
micelles provided high siRNA binding efficiency. In addition, siRNA
delivered by PEI-SA carriers also demonstrated significantly high
cellular uptake even in the presence of serum proteins. The
post-transcriptional gene silencing efficiency was greatly improved by
the polyplex formulated by 10k PEI-SA/siRNA. The amphiphilic
structure of PEI-SA micelles provided advantages for multifunctional
tasks; where the hydrophilic shell modified with cationic charges can
electrostatically interact with DNA or siRNA, and the hydrophobic
core can serve as payloads for hydrophobic drugs, making it a
promising multifunctional vehicle for both genetic and chemotherapy
application.
Abstract: We aimed to investigate how can target and optimize
pulmonary delivery distribution by changing physicochemical
characteristics of instilled liquid.Therefore, we created a new liquids
group:
a. eligible for desired distribution within lung because of
assorted physicochemical characteristics
b. capable of being augmented with a broad range of
chemicals inertly
c. no interference on respiratory function
d. compatible with airway surface liquid
We developed forty types of new liquid,were composed of
Carboxymethylcellulose sodium,Glycerin and different types of
Polysorbates.Viscosity was measured using a Programmable
Rheometer and surface tension by KRUSS Tensiometer.We
subsequently examined the liquids and delivery protocols by simple
and branched glass capillary tube models of airways.Eventually,we
explored pulmonary distribution of liquids being augmented with
technetium-99m in mechanically ventilated rabbits.We used a single
head large field of view gamma camera.Kinematic viscosity between
0.265Stokes and 0.289Stokes,density between 1g/cm3 and 1.5g/cm3
and surface tension between 25dyn/cm and 35dyn/cm were the most
acceptable.
Abstract: In the past few decades, researchers have witnessed a
paradigm shift in Human Resource Management-from individual
performance to organizational outcomes with the role of Human
resource (HR) managers becoming increasingly significant to the
organization. In such a context, it is important to examine HR
practices from a strategic perspective on the sustained competitive
advantage (SCA) of the organizations. The present study explores
how Indian organisations look at their human resources strategically
when faced with competitive environment. Also, it explores strategic
initiatives being taken to manage human resources within the
organisations and how these initiatives promote SCA in terms of
enhancing the overall customer-centric delivery of goods and
services.
Abstract: Nowadays, where most of the leading economies are
service oriented and e-business is being widely used for their
management, supply chain management has become one of the most
studied and practiced fields. Quality has an important role on today-s
business processes, so it is important to understand the impact of IT
service quality on the performance of supply chains. This paper will
start by analyzing the Supply Chain Operations Reference (SCOR)
model and each of its five activities: Plan, Source, Make, Delivery,
and Return. This article proposes a framework for analyzing Effect of
IT Service Quality on Supply Chain Performance. Using the
proposed framework, hypotheses are framed for the direct effect of IT
service quality on Supply Chain Performance and its indirect effect
through effective Supply Chain Management. The framework will be
validated empirically based on the surveys of executives of various
organizations and statistical analyses of the data collected.
Abstract: Business rules are widely used within the services
sector. They provide consistency and allow relatively unskilled staff
to process complex transactions correctly. But there are many
examples where the rules themselves have an impact on the costs and
profits of an organisation. Financial services, transport and human
services are areas where the rules themselves can impact the bottom
line in a predictable way. If this is the case, how can we find that set
of rules that maximise profit, performance or customer service, or
any other key performance indicators? The manufacturing, energy
and process industries have embraced mathematical optimisation
techniques to improve efficiency, increase production and so on. This
paper explores several real world (but simplified) problems in the
services sector and shows how business rules can be optimised. It
also examines the similarities and differences between the service
and other sectors, and how optimisation techniques could be used to
deliver similar benefits.
Abstract: Estimation time and cost of work completion in a
project and follow up them during execution are contributors to
success or fail of a project, and is very important for project
management team. Delivering on time and within budgeted cost
needs to well managing and controlling the projects. To dealing with
complex task of controlling and modifying the baseline project
schedule during execution, earned value management systems have
been set up and widely used to measure and communicate the real
physical progress of a project. But it often fails to predict the total
duration of the project. In this paper data mining techniques is used
predicting the total project duration in term of Time Estimate At
Completion-EAC (t). For this purpose, we have used a project with
90 activities, it has updated day by day. Then, it is used regular
indexes in literature and applied Earned Duration Method to
calculate time estimate at completion and set these as input data for
prediction and specifying the major parameters among them using
Clem software. By using data mining, the effective parameters on
EAC and the relationship between them could be extracted and it is
very useful to manage a project with minimum delay risks. As we
state, this could be a simple, safe and applicable method in prediction
the completion time of a project during execution.
Abstract: The excellent suitability of the externally excited synchronous
machine (EESM) in automotive traction drive applications
is justified by its high efficiency over the whole operation range and
the high availability of materials. Usually, maximum efficiency is
obtained by modelling each single loss and minimizing the sum of all
losses. As a result, the quality of the optimization highly depends on
the precision of the model. Moreover, it requires accurate knowledge
of the saturation dependent machine inductances. Therefore, the
present contribution proposes a method to minimize the overall losses
of a salient pole EESM and its inverter in steady state operation based
on measurement data only. Since this method does not require any
manufacturer data, it is well suited for an automated measurement
data evaluation and inverter parametrization. The field oriented control
(FOC) of an EESM provides three current components resp. three
degrees of freedom (DOF). An analytic minimization of the copper
losses in the stator and the rotor (assuming constant inductances) is
performed and serves as a first approximation of how to choose the
optimal current reference values. After a numeric offline minimization
of the overall losses based on measurement data the results are
compared to a control strategy that satisfies cos (ϕ) = 1.
Abstract: The process of laser absorption in the skin during
laser irradiation was a critical point in medical application
treatments. Delivery the correct amount of laser light is a critical
element in photodynamic therapy (PDT). More amounts of laser
light able to affect tissues in the skin and small amount not able to
enhance PDT procedure in skin. The knowledge of the skin tone
laser dependent distribution of 635 nm radiation and its penetration
depth in skin is a very important precondition for the investigation of
advantage laser induced effect in (PDT) in epidermis diseases
(psoriasis). The aim of this work was to estimate an optimum effect
of diode laser (635 nm) on the treatment of epidermis diseases in
different color skin. Furthermore, it is to improve safety of laser in
PDT in epidermis diseases treatment. Advanced system analytical
program (ASAP) which is a new approach in investigating the PDT,
dependent on optical properties of different skin color was used in
present work. A two layered Realistic Skin Model (RSM); stratum
corneum and epidermal with red laser (635 nm, 10 mW) were used
for irradiative transfer to study fluence and absorbance in different
penetration for various human skin colors. Several skin tones very
fair, fair, light, medium and dark are used to irradiative transfer. This
investigation involved the principles of laser tissue interaction when
the skin optically injected by a red laser diode. The results
demonstrated that the power characteristic of a laser diode (635 nm)
can affect the treatment of epidermal disease in various color skins.
Power absorption of the various human skins were recorded and
analyzed in order to find the influence of the melanin in PDT
treatment in epidermal disease. A two layered RSM show that the
change in penetration depth in epidermal layer of the color skin has a
larger effect on the distribution of absorbed laser in the skin; this is
due to the variation of the melanin concentration for each color.
Abstract: EPA (Ethernet for Plant Automation) resolves the nondeterministic problem of standard Ethernet and accomplishes real-time communication by means of micro-segment topology and deterministic scheduling mechanism. This paper studies the real-time performance of EPA periodic data transmission from theoretical and experimental perspective. By analyzing information transmission characteristics and EPA deterministic scheduling mechanism, 5 indicators including delivery time, time synchronization accuracy, data-sending time offset accuracy, utilization percentage of configured timeslice and non-RTE bandwidth that can be used to specify the real-time performance of EPA periodic data transmission are presented and investigated. On this basis, the test principles and test methods of the indicators are respectively studied and some formulas for real-time performance of EPA system are derived. Furthermore, an experiment platform is developed to test the indicators of EPA periodic data transmission in a micro-segment. According to the analysis and the experiment, the methods to improve the real-time performance of EPA periodic data transmission including optimizing network structure, studying self-adaptive adjustment method of timeslice and providing data-sending time offset accuracy for configuration are proposed.
Abstract: The importance of hints in an intelligent tutoring system is well understood. The problems however related to their delivering are quite a few. In this paper we propose delivering of hints to be based on considering their usefulness. By this we mean that a hint is regarded as useful to a student if the student has succeeded to solve a problem after the hint was suggested to her/him. Methods from the theory of partial orderings are further applied facilitating an automated process of offering individualized advises on how to proceed in order to solve a particular problem.
Abstract: The emergence of networked information and communication has transformed the accessibility and delivery of scholarly information and fundamentally impacted on the processes of research and scholarly communication. The purpose of this study is to investigate disciplinary differences in the use of networked information for research and scholarly communication at Sultan Qaboos University, Oman. This study has produced quantitative data about how and why academics within different disciplines utilize networked information that is made available either internally through the university library, or externally through networked services accessed by the Internet. The results indicate some significant differences between the attitudes and practice of academics in the science disciplines when compared to those from the social sciences and humanities. While respondents from science disciplines show overall longer and more frequent use of networked information, respondents from humanities and social sciences indicated more positive attitudes and a greater degree of satisfaction toward library networked services.
Abstract: Genetic Zone Routing Protocol (GZRP) is a new
hybrid routing protocol for MANETs which is an extension of ZRP
by using Genetic Algorithm (GA). GZRP uses GA on IERP and BRP
parts of ZRP to provide a limited set of alternative routes to the
destination in order to load balance the network and robustness
during node/link failure during the route discovery process. GZRP is
studied for its performance compared to ZRP in many folds like
scalability for packet delivery and proved with improved results. This
paper presents the results of the effect of load balancing on GZRP.
The results show that GZRP outperforms ZRP while balancing the
load.
Abstract: As the development of digital technology is increasing,
Digital cinema is getting more spread.
However, content copy and attack against the digital cinema becomes
a serious problem. To solve the above security problem, we propose
“Additional Watermarking" for digital cinema delivery system. With
this proposed “Additional watermarking" method, we protect content
copyrights at encoder and user side information at decoder. It realizes
the traceability of the watermark embedded at encoder.
The watermark is embedded into the random-selected frames using
Hash function. Using it, the embedding position is distributed by Hash
Function so that third parties do not break off the watermarking
algorithm.
Finally, our experimental results show that proposed method is much
better than the convenient watermarking techniques in terms of
robustness, image quality and its simple but unbreakable algorithm.
Abstract: From an economic standpoint the current and future
road traffic situation in urban areas is a cost factor. Traffic jams and
congestion prolong journey times and tie up resources in trucks and
personnel. Many discussions about imposing charges or tolls for
cities in Europe in order to reduce traffic congestion are currently in
progress. Both of these effects lead – directly or indirectly - to
additional costs for the urban distribution systems in retail
companies. One approach towards improving the efficiency of retail
distribution systems, and thus towards avoiding negative
environmental factors in urban areas, is horizontal collaboration for
deliveries to retail outlets – Urban Retail Logistics. This paper
presents a classification system to help reveal where cooperation
between retail companies is possible and makes sense for deliveries
to retail outlets in urban areas.
Abstract: Cellular networks provide voice and data services to the users with mobility. To deliver services to the mobile users, the cellular network is capable of tracking the locations of the users, and allowing user movement during the conversations. These capabilities are achieved by the location management. Location management in mobile communication systems is concerned with those network functions necessary to allow the users to be reached wherever they are in the network coverage area. In a cellular network, a service coverage area is divided into smaller areas of hexagonal shape, referred to as cells. The cellular concept was introduced to reuse the radio frequency. Continued expansion of cellular networks, coupled with an increasingly restricted mobile spectrum, has established the reduction of communication overhead as a highly important issue. Much of this traffic is used in determining the precise location of individual users when relaying calls, with the field of location management aiming to reduce this overhead through prediction of user location. This paper describes and compares various location management schemes in the cellular networks.
Abstract: Obsessive-Compulsive Disorder (OCD) is a common
and disabling condition. Therapist-delivered treatments that use
exposure and response prevention have been found to be very
effective in treating OCD, although they are costly and associated
with high rates of attrition. Effective treatments that can be made
widely available without the need for therapist contact are urgently
needed. This case study represents the first published investigation of
a self-administered cognitive treatment for OCD in a 50-year old
female with a 20 year history of OCD. The treatment evaluation
occurred over 27 weeks, including 12 weeks of self-administration of
the Danger Ideation Reduction Therapy (DIRT) program. Decreases
of between 23% to 33% on measures from pre-treatment to follow-up
were observed. Bearing in mind the methodological limitations
associated with a case study, we conclude that the results reported
here are encouraging and indicate that further research effort
evaluating the effectiveness of self-administered DIRT is warranted.