Abstract: Batch production plants provide a wide range of
scheduling problems. In pharmaceutical industries a batch process
is usually described by a recipe, consisting of an ordering of tasks
to produce the desired product. In this research work we focused
on pharmaceutical production processes requiring the culture of
a microorganism population (i.e. bacteria, yeasts or antibiotics).
Several sources of uncertainty may influence the yield of the culture
processes, including (i) low performance and quality of the cultured
microorganism population or (ii) microbial contamination. For
these reasons, robustness is a valuable property for the considered
application context. In particular, a robust schedule will not collapse
immediately when a cell of microorganisms has to be thrown away
due to a microbial contamination. Indeed, a robust schedule should
change locally in small proportions and the overall performance
measure (i.e. makespan, lateness) should change a little if at all.
In this research work we formulated a constraint programming
optimization (COP) model for the robust planning of antibiotics
production. We developed a discrete-time model with a multi-criteria
objective, ordering the different criteria and performing a
lexicographic optimization. A feasible solution of the proposed
COP model is a schedule of a given set of tasks onto available
resources. The schedule has to satisfy tasks precedence constraints,
resource capacity constraints and time constraints. In particular
time constraints model tasks duedates and resource availability
time windows constraints. To improve the schedule robustness, we
modeled the concept of (a, b) super-solutions, where (a, b) are input
parameters of the COP model. An (a, b) super-solution is one in
which if a variables (i.e. the completion times of a culture tasks)
lose their values (i.e. cultures are contaminated), the solution can be
repaired by assigning these variables values with a new values (i.e.
the completion times of a backup culture tasks) and at most b other
variables (i.e. delaying the completion of at most b other tasks).
The efficiency and applicability of the proposed model is
demonstrated by solving instances taken from a real-life
pharmaceutical company. Computational results showed that
the determined super-solutions are near-optimal.
Abstract: Steel slag is a by-product of the steel industry and can
be used potentially as aggregate in the asphalt mixture. This study
evaluates the use of Steel Slag Aggregates (SSA) as a substitute for
natural aggregates in the production of hot mix asphalt (HMA) for
road construction. Based on intensive laboratory testing program, the
characteristic properties of SSA were assessed to determine its
suitability to be used in HMA. Four different percentages (0, 50, 75,
and 100%) of SSA were used, and the proposed mix designs for
HMA were conducted in accordance with Marshall mix design. The
experiment results revealed that the addition of SSA has a significant
improvement on the properties of HMA. An increase in density and
stability and a reduction in flow and air voids values were clearly
observed in specimens prepared with 100% SSA. It is concluded that
the steel slag can be considered reasonable alternative source of
aggregate for concrete asphalt mixture production.
Abstract: Determination of genetic variation is useful for plant
breeding and hence production of more efficient plant species under
different conditions, like drought stress. In this study a sample of 28
recombinant inbred lines (RILs) of wheat developed from the cross of
Norstar and Zagross varieties, together with their parents, were
evaluated for two years (2010-2012) under normal and water stress
conditions using split plot design with three replications. Main plots
included two irrigation treatments of 70 and 140 mm evaporation
from Class A pan and sub-plots consisted of 30 genotypes. The effect
of genotypes and interaction of genotypes with years and water
regimes were significant for all characters. Significant genotypic
effect implies the existence of genetic variation among the lines
under study. Heritability estimates were high for 1000 grain weight
(0.87). Biomass and grain yield showed the lowest heritability values
(0.42 and 0.50, respectively). Highest genotypic and phenotypic
coefficients of variation (GCV and PCV) belonged to harvest index.
Moderate genetic advance for most of the traits suggested the
feasibility of selection among the RILs under investigation. Some
RILs were higher yielding than either parent at both environments.
Abstract: The possibility of application the dietary fibers in
production of crackers was observed in this work, as well as their
influence on rheological and textural properties on the dough for
crackers and influence on sensory properties of obtained crackers.
Three different dietary fibers, oat, potato and pea fibers, replaced
10% of wheat flour. Long fermentation process and baking test
method were used for crackers production. The changes of dough for
crackers were observed by rheological methods of determination the
viscoelastic dough properties and by textural measurements. Sensory
quality of obtained crackers was described using quantity descriptive
method (QDA) by trained members of descriptive panel. Additional
analysis of crackers surface was performed by videometer. Based on
rheological determination, viscoelastic properties of dough for
crackers were reduced by application of dietary fibers. Manipulation
of dough with 10% of potato fiber was disabled, thus the recipe
modification included increase in water content at 35%. Dough
compliance to constant stress for samples with dietary fibers
decreased, due to more rigid and stiffer dough consistency compared
to control sample. Also, hardness of dough for these samples
increased and dough extensibility decreased. Sensory properties of
final products, crackers, were reduced compared to control sample.
Application of dietary fibers affected mostly hardness, structure and
crispness of the crackers. Observed crackers were low marked for
flavor and taste, due to influence of fibers specific aroma. The sample
with 10% of potato fibers and increased water content was the most
adaptable to applied stresses and to production process. Also this
sample was close to control sample without dietary fibers by
evaluation of sensory properties and by results of videometer method.
Abstract: Main objective of this paper is to establish a link
between inertial forces of the bearings used in construction of wind
power plant and its behavior. Using bearings with lower inertial
forces has the immediate effect of decreasing inertia rotor system,
with significant results in increased energy efficiency, due to
decreased friction forces between rollers and raceways. The F.E.M.
analysis shows the appearance of uniform contact stress at the ends of
the rollers, demonstrated the necessity of production of low mass
bearings. Favorable results are expected in the economic field, by
reducing material consumption and by increasing the durability of
bearings. Using low mass bearings with hollow rollers instead of
solid rollers has an impact on working temperature, on vibrations and
noise which decrease. Implementation of types of hollow rollers of
cylindrical tubular type, instead of expensive rollers with logarithmic
profile, will bring significant inertial forces decrease with large
benefits in behavior of wind power plant.
Abstract: Effects of nicotine on pre-partum body weight and
preimplantation embryonic development has been reported
previously. Present study was conducted to determine the effects of
annatto (Bixa orellana)-derived delta-tocotrienol (TCT) (with
presence of 10% gamma-TCT isomer) on the nicotine-induced
reduction in body weight and 8-cell embryonic growth in mice.
Twenty-four 6-8 weeks old (23-25g) female balb/c mice were
randomly divided into four groups (G1-G4; n=6). Those groups were
subjected to the following treatments for 7 consecutive days: G1
(control) were gavaged with 0.1 ml tocopherol stripped corn oil. G2
was subcutaneously (s.c.) injected with 3 mg/kg/day of nicotine. G3
received concurrent treatment of nicotine (3 mg/kg/day) and 60
mg/kg/day of δ-TCT mixture (contains 90% delta & 10% gamma
isomers) and G4 was given 60 mg/kg/day of δ-TCT mixture alone.
Body weights were recorded daily during the treatment. On Day 8,
females were superovulated with 5 IU Pregnant Mare’s Serum
Gonadotropin (PMSG) for 48 hours followed with 5 IU human
Chorionic Gonadotropin (hCG) before mated with males at the ratio
of 1:1. Females were sacrificed by cervical dislocation for embryo
collection 48 hours post-coitum. Collected embryos were cultured in
vitro. Results showed that throughout Day 1 to Day 7, the body
weight of nicotine treated group (G2) was significantly lower
(p
Abstract: Industries produce millions of cubic meters of effluent
every year and the wastewater produced may be released into the
surrounding water bodies, treated on-site or at municipal treatment
plants. The determination of organic matter in the wastewater
generated is very important to avoid any negative effect on the
aquatic ecosystem. The scope of the present work is to assess the
physicochemical composition of the wastewater produced from one
of the brewery industry in South Africa. This is to estimate the
environmental impact of its discharge into the receiving water bodies
or the municipal treatment plant. The parameters monitored for the
quantitative analysis of brewery wastewater include biological
oxygen demand (BOD5), chemical oxygen demand (COD), total
suspended solids, volatile suspended solids, ammonia, total oxidized
nitrogen, nitrate, nitrite, phosphorus and alkalinity content. In
average, the COD concentration of the brewery effluent was 5340.97
mg/l with average pH values of 4.0 to 6.7. The BOD5 and the solids
content of the wastewater from the brewery industry were high. This
means that the effluent is very rich in organic content and its
discharge into the water bodies or the municipal treatment plant could
cause environmental pollution or damage the treatment plant. In
addition, there were variations in the wastewater composition
throughout the monitoring period. This might be as a result of
different activities that take place during the production process, as
well as the effects of peak period of beer production on the water
usage.
Abstract: The phytotoxicity of heavy metals can be expressed
on roots and visible part of plants and is characterized by molecular
and metabolic answers at various levels of organization of the whole
plant. The present study was undertaken on two varieties of broad
bean Vicia faba (Sidi Aïch and Super Aguadulce). The device was
mounted on a substrate prepared by mixing sand, soil and compost,
the substrate was artificially contaminated with three doses of lead
nitrate [Pb(NO3)2] 0, 500 and 1000 ppm. Our objective is to follow
the behavior of plant opposite the stress by evaluating the
physiological parameters. The results reveal a reduction in the
parameters of the productivity (chlorophyll and proteins production)
with an increase in the osmoregulators (soluble sugars and
proline).These results show that the production of broad bean is
strongly modified by the disturbance of its internal physiology under
lead exposure.
Abstract: The recent interest in alternative and renewable
energy systems results in increased installed capacity ratio of such
systems in total energy production of the world. Specifically, Wind
Energy Conversion Systems (WECS) draw significant attention
among possible alternative energy options, recently. On the contrary
of the positive points of penetrating WECS in all over the world in
terms of environment protection, energy independence of the
countries, etc., there are significant problems to be solved for the grid
connection of large scale WECS. The reactive power regulation,
voltage variation suppression, etc. can be presented as major issues to
be considered in this regard. Thus, this paper evaluates the
application of a Static VAr Compensator (SVC) unit for the reactive
power regulation and operation continuity of WECS during a fault
condition. The system is modeled employing the IEEE 13 node test
system. Thus, it is possible to evaluate the system performance with
an overall grid simulation model close to real grid systems. The
overall simulation model is developed in
MATLAB/Simulink/SimPowerSystems® environments and the
obtained results effectively match the target of the provided study.
Abstract: Different designs of attenuator systems have been
studied in this research; new analysis have been done on existed
designs considering fibers effect on air flow; it was comprehended
that, at fibers presence, there is an air flow which agglomerates fibers
as a negative effect. So some new representations have been designed
and CFD analysis has been done on them. Afterwards, one of these
representations selected as the most optimum and effective design
which is brought in this paper.
Abstract: Tannase (tannin acyl hydrolase, E.C.3.1.1.20) is an
important hydrolysable enzyme with innumerable applications and
industrial potential. In the present study, a kinetic model has been
developed for the batch fermentation used for the production of
tannase by A.flavus MTCC 3783. Maximum tannase activity of
143.30 U/ml was obtained at 96 hours under optimum operating
conditions at 35oC, an initial pH of 5.5 and with an inducer tannic
acid concentration of 3% (w/v) for a fermentation period of 120
hours. The biomass concentration reaches a maximum of 6.62 g/l at
96 hours and further there was no increase in biomass concentration
till the end of the fermentation. Various unstructured kinetic models
were analyzed to simulate the experimental values of microbial
growth, tannase activity and substrate concentration. The Logistic
model for microbial growth , Luedeking - Piret model for production
of tannase and Substrate utilization kinetic model for utilization of
substrate were capable of predicting the fermentation profile with
high coefficient of determination (R2) values of 0.980, 0.942 and
0.983 respectively. The results indicated that the unstructured models
were able to describe the fermentation kinetics more effectively.
Abstract: Life cycle assessment is a technique to assess the
environmental aspects and potential impacts associated with a
product, process, or service, by compiling an inventory of relevant
energy and material inputs and environmental releases; evaluating the
potential environmental impacts associated with identified inputs and
releases; and interpreting the results to help you make a more
informed decision. In this paper, the life cycle assessment of
aluminum and beech wood as two commonly used materials in Egypt
for window frames are heading, highlighting their benefits and
weaknesses. Window frames of the two materials have been assessed
on the basis of their production, energy consumption and
environmental impacts. It has been found that the climate change of
the windows made of aluminum and beech wood window, for a
reference window (1.2m×1.2m), are 81.7 mPt and -52.5 mPt impacts
respectively. Among the most important results are: fossil fuel
consumption, potential contributions to the green building effect and
quantities of solid waste tend to be minor for wood products
compared to aluminum products; incineration of wood products can
cause higher impacts of acidification and eutrophication than
aluminum, whereas thermal energy can be recovered.
Abstract: In this paper comprehensive studies have been carried
out for the design optimization of a waste heat recovery system for
effectively utilizing the domestic air conditioner heat energy for
producing hot water. Numerical studies have been carried for the
geometry optimization of a waste heat recovery system for domestic
air conditioners. Numerical computations have been carried out using
a validated 2d pressure based, unsteady, 2nd-order implicit, SST k-ω
turbulence model. In the numerical study, a fully implicit finite
volume scheme of the compressible, Reynolds-Averaged, Navier-
Stokes equations is employed. At identical inflow and boundary
conditions various geometries were tried and effort has been taken for
proposing the best design criteria. Several combinations of pipe line
shapes viz., straight and spiral with different number of coils for the
radiator have been attempted and accordingly the design criteria has
been proposed for the waste heat recovery system design. We have
concluded that, within the given envelope, the geometry optimization
is a meaningful objective for getting better performance of waste heat
recovery system for air conditioners.
Abstract: A lower consumption of thermal energy will
contribute not only to a reduction in the running costs, but also in the
reduction of pollutant emissions that contribute to the greenhouse
effect. Cogeneration or CHP (Combined Heat and Power) is the
system that produces power and usable heat simultaneously by
decreasing the pollutant emissions and increasing the efficiency.
Combined production of mechanical or electrical and thermal energy
using a simple energy source, such as oil, coal, natural or liquefied
gas, biomass or the sun; affords remarkable energy savings and
frequently makes it possible to operate with greater efficiency when
compared to a system producing heat and power separately. This
study aims to bring out the contributions of cogeneration systems to
the environment and sustainability by saving the energy and reducing
the emissions. In this way we made a comprehensive investigation in
the literature by focusing on the environmental aspects of the
cogeneration systems. In the light of these studies we reached that,
cogeneration systems must be consider in sustainability and their
benefits on protecting the ecology must be investigated.
Abstract: Chalcopyrite (CuFeS2) is the most common primary
mineral used for the commercial production of copper. The low
dissolution efficiency of chalcopyrite in sulfate media has prevented
an efficient industrial leaching of this mineral in sulfate media. Ferric
ions, bacteria, oxygen and other oxidants have been used as oxidizing
agents in the leaching of chalcopyrite in sulfate and chloride media
under atmospheric or pressure leaching conditions. Two leaching
methods were studied to evaluate chalcopyrite (CuFeS2) dissolution
in acid media. First, the conventional oxidative acid leaching method
was carried out using sulfuric acid (H2SO4) and potassium
dichromate (K2Cr2O7) as oxidant at atmospheric pressure. Second,
microwave-assisted acid leaching was performed using the
microwave accelerated reaction system (MARS) for same reaction
media. Parameters affecting the copper extraction such as leaching
time, leaching temperature, concentration of H2SO4 and
concentration of K2Cr2O7 were investigated. The results of
conventional acid leaching experiments were compared to the
microwave leaching method. It was found that the copper extraction
obtained under high temperature and high concentrations of oxidant
with microwave leaching is higher than those obtained
conventionally. 81% copper extraction was obtained by the
conventional oxidative acid leaching method in 180 min, with the
concentration of 0.3 mol/L K2Cr2O7 in 0.5M H2SO4 at 50 ºC, while
93.5% copper extraction was obtained in 60 min with microwave
leaching method under same conditions.
Abstract: Application of biochar to arable soils represents a new
approach to restore soil health and quality. Many studies reported the
positive effect of biochar application on soil fertility and
development of soil microbial community. Moreover biochar may
affect the soil water retention, but this effect has not been sufficiently
described yet. Therefore this study deals with the influence of
biochar application on: microbial activities in soil, availability of
mineral nitrogen in soil for microorganisms, mineral nitrogen
retention and plant production. To demonstrate the effect of biochar
addition on the above parameters, the pot experiment was realized.
As a model crop, Lactuca sativa L. was used and cultivated from
December 10th 2014 till March 22th 2015 in climate chamber in
thoroughly homogenized arable soil with and without addition of
biochar. Five variants of experiment (V1 – V5) with different regime
of irrigation were prepared. Variants V1 – V2 were fertilized by
mineral nitrogen, V3 – V4 by biochar and V5 was a control. The
significant differences were found only in plant production and
mineral nitrogen retention. The highest content of mineral nitrogen
in soil was detected in V1 and V2, about 250 % in comparison with
the other variants. The positive effect of biochar application on soil
fertility, mineral nitrogen availability was not found. On the other
hand results of plant production indicate the possible positive effect
of biochar application on soil water retention.
Abstract: ANDASA is a knowledge management platform for
the capitalization of knowledge and cultural assets for the artistic and
cultural sectors. It was built based on the priorities expressed by the
participating artists. Through mapping artistic activities and
specificities, it enables to highlight various aspects of the artistic
research and production. Such instrument will contribute to create
networks and partnerships, as it enables to evidentiate who does
what, in what field, using which methodology. The platform is
accessible to network participants and to the general public.
Abstract: Crops diversity and maintaining and enhancing the
fertility of agricultural lands are basic principles of organic farming.
With a wider range of crops in agroecosystem can improve the ability
to control weeds, pests and diseases, and the performance of crops
rotation and food safety. In this sense, the main objective of the
research was to study the productivity and chemical composition of
some alternative crops and their adaptability to soil and climatic
conditions of the agricultural area in Southern Romania and to
cultivation in the organic farming system. The alternative crops were:
lentil (7 genotypes); five species of grain legumes (5 genotypes); four
species of oil crops (5 genotypes). The seed production was, on
average: 1343 kg/ha of lentil; 2500 kg/ha of field beans; 2400 kg/ha
of chick peas and blackeyed peas; more than 2000 kg/ha of atzuki
beans, over 1250 kg/ha of fenugreek; 2200 kg/ha of safflower; 570
kg/ha of oil pumpkin; 2150 kg/ha of oil flax; 1518 kg/ha of camelina.
Regarding chemical composition, lentil seeds contained: 22.18%
proteins, 3.03% lipids, 33.29% glucides, 4.00% minerals, and 259.97
kcal energy values. For field beans: 21.50% proteins, 4.40% lipids,
63.90% glucides, 5.85% minerals, 395.36 kcal energetic value. For
chick peas: 21.23% proteins, 4.55% lipids, 53.00% glucides, 3.67%
minerals, 348.22 kcal energetic value. For blackeyed peas: 23.30%
proteins, 2.10% lipids, 68.10% glucides, 3.93% minerals, 350.14 kcal
energetic value. For adzuki beans: 21.90% proteins, 2.60% lipids,
69.30% glucides, 4.10% minerals, 402.48 kcal energetic value. For
fenugreek: 21.30% proteins, 4.65% lipids, 63.83% glucides, 5.69%
minerals, 396.54 kcal energetic value. For safflower: 12.60%
proteins, 28.37% lipids, 46.41% glucides, 3.60% minerals, 505.78
kcal energetic value. For camelina: 20.29% proteins, 31.68% lipids,
36.28% glucides, 4.29% minerals, 526.63 kcal energetic value. For
oil pumpkin: 29.50% proteins, 36.92% lipids, 18.50% glucides,
5.41% minerals, 540.15 kcal energetic value. For oil flax: 22.56%
proteins, 34.10% lipids, 27.73% glucides, 5.25% minerals, 558.45
kcal energetic value.
Abstract: The purpose of the present study is to find the efficacy
of high school student self-assessment of written production. It aimed
to explore the following two research questions: 1) How is topic
development of their written production improved after student
self-assessment and teacher feedback? 2) Does the consistency
between student self-assessment and teacher assessment develop after
student self-assessment and teacher feedback? The data came from the
written production of 82 Japanese high school students aged from 16
to 18 years old, an American English teacher and one Japanese English
teacher. Students were asked to write English compositions, about 150
words, for thirty minutes without using dictionaries. It was conducted
twice at intervals of two months. Students were supposed to assess
their own compositions by themselves. Teachers also assessed
students’ compositions using the same assessment sheet. The results
showed that both teachers and students assessed the second
compositions higher than the first compositions. However, there was
not the development of the consistency in coherence.
Abstract: Biodiesel production from vegetable oil will produce
glycerol as by-product about 10% of the biodiesel production. The
amount of glycerol that was produced needed alternative way to
handling immediately so as to not become the waste that polluted
environment. One of the solutions was to process glycerol to
polyglycidyl nitrate (PGN). PGN is synthesized from glycerol by
three-step reactions i.e. nitration of glycerol, cyclization of 13-
dinitroglycerine and polymerization of glycosyl nitrate. Optimum
condition of nitration of glycerol with nitric acid has not been known.
Thermodynamic feasibility should be done before run experiments in
the laboratory. The aim of this study was to determine the parameters
those affect nitration of glycerol and nitric acid and chose the
operation condition. Many parameters were simulated to verify its
possibility to experiment under conditions which would get the
highest conversion of 1, 3-dinitroglycerine and which was the ideal
condition to get it. The parameters that need to be studied to obtain
the highest conversion of 1, 3-dinitroglycerine were mol ratio of
nitric acid/glycerol, reaction temperature, mol ratio of
glycerol/dichloromethane and pressure. The highest conversion was
obtained in the range of mol ratio of nitric acid /glycerol between 2/1
– 5/1, reaction temperature of 5-25oC and pressure of 1 atm. The
parameters that need to be studied further to obtain the highest
conversion of 1.3 DNG are mol ratio of nitric acid/glycerol and
reaction temperature.