Abstract: The physical methods for RNA secondary structure prediction are time consuming and expensive, thus methods for computational prediction will be a proper alternative. Various algorithms have been used for RNA structure prediction including dynamic programming and metaheuristic algorithms. Musician's behaviorinspired harmony search is a recently developed metaheuristic algorithm which has been successful in a wide variety of complex optimization problems. This paper proposes a harmony search algorithm (HSRNAFold) to find RNA secondary structure with minimum free energy and similar to the native structure. HSRNAFold is compared with dynamic programming benchmark mfold and metaheuristic algorithms (RnaPredict, SetPSO and HelixPSO). The results showed that HSRNAFold is comparable to mfold and better than metaheuristics in finding the minimum free energies and the number of correct base pairs.
Abstract: A major part of the flow field involves no complicated
turbulent behavior in many turbulent flows. In this research work, in
order to reduce required memory and CPU time, the flow field was
decomposed into several blocks, each block including its special
turbulence. A two dimensional backward facing step was considered
here. Four combinations of the Prandtl mixing length and standard k-
E models were implemented as well. Computer memory and CPU
time consumption in addition to numerical convergence and accuracy
of the obtained results were mainly investigated. Observations
showed that, a suitable combination of turbulence models in different
blocks led to the results with the same accuracy as the high order
turbulence model for all of the blocks, in addition to the reductions in
memory and CPU time consumption.
Abstract: In this paper, we consider nested sliding mode control of SISO nonlinear systems, perturbed by bounded matched and unmatched uncertainties. The systems are assumed to be in strict-feedback form. A step wise procedure is introduced to obtain the controller. In each step, a continuous sliding mode controller is designed as virtual control law. Then the next step sliding surface is defined by using this virtual controller. These sliding surfaces are selected as nonlinear static functions of the system states. Finally in the last step, smooth static state feedback control law is determined such that the output reaches the desired set-point while the system is forced arbitrary close to the intersection of sliding surfaces and the states remain bounded.
Abstract: Organochlorine pesticides (OCPs) are known to be
persistent and bioaccumulative toxicants that may cause reproductive
impairments in wildlife as well as human. The current study uses the
snail-eating turtle Malayemys macrocephala, a long-lived animal
commonly distribute in rice field habitat in central part of Thailand,
as a sentinel to monitor OCP contamination in environment. The
nest soil, complete clutch of eggs, and blood of the turtle were
collected from agricultural areas in the Chao Phraya River Basin,
Thailand during the nesting season of 2007-2008. The novel
methods for tissue extraction by an accelerated solvent extractor
(ASE, for egg) and liquid-liquid extraction (for blood) have been
developed. The nineteen OCP residues were analyzed by gas
chromatography with micro-electron captured detector (GC-μECD).
The validated methods have met requirements of the AOAC
standard. The results indicated that significant amounts of OCPs are
still contaminated in nest soil and eggs of the turtle even though the
OCPs had been banned in this area for many years. This suggested
the potential risk to health of wildlife as well as human in the area.
Abstract: In this paper we discuss a set of guidelines which
could be adapted when designing an audio user interface for the
visually impaired. It is based on an audio environment that is
focused on audio positioning. Unlike current applications which only
interpret Graphical User Interface (GUI) for the visually impaired,
this particular audio environment bypasses GUI to provide a direct
auditory output. It presents the capability of two dimensional (2D)
navigation on audio interfaces. This paper highlights the significance
of a 2D audio environment with spatial information in the context
of the visually impaired. A thorough usability study has been conducted
to prove the applicability of proposed design guidelines for
these auditory interfaces. While proving these guidelines, previously
unearthed design aspects have been revealed in this study.
Abstract: A pilot project was carried out in 2007 by the senior
students of Cyprus International University, aiming to minimize the
total cost of waste collection in Northern Cyprus. Many developed
and developing countries have cut their transportation costs – which
lies between 30-40% – down at a rate of 40% percent, by
implementing network models for their route assignments.
Accordingly, a network model was implemented at Göçmenköy
district, to optimize and standardize waste collection works. The
work environment of the employees were also redesigned to provide
maximum ergonomy and to increase productivity, efficiency and
safety. Following the collection of the required data including waste
densities, lengths of roads and population, a model was constructed
to allocate the optimal route assignment for the waste collection
trucks at Göçmenköy district.
Abstract: Energy consumption is one of the indices in
determining the levels of development of a nation. Therefore,
availability of energy supply to all sectors of life in any country is
crucial for its development. These exists shortage of all kinds of
energy, particularly electricity which is badly needed for economic
development. Electricity from the sun which is quite abundant in
most of the developing countries is used in rural areas to meet basic
electricity needs of a rural community. Today-s electricity supply in
Myanmar is generated by fuel generators and hydroelectric power
plants. However, far-flung areas which are away from National Grids
cannot enjoy the electricity generated by these sources. Since
Myanmar is a land of plentiful sunshine, especially in central and
southern regions of the country, the first form of energy- solar energy
could hopefully become the final solution to its energy supply
problem. The direct conversion of solar energy into electricity using
photovoltaic system has been receiving intensive installation not only
in developed countries but also in developing countries. It is mainly
intended to present solar energy potential and application in
Myanmar. It is also wanted to get the benefits of using solar energy
for people in remote areas which are not yet connected to the national
grids because of the high price of fossil fuel.
Abstract: In this paper a novel high output impedance, low input impedance, wide bandwidth, very simple current mirror with input and output voltage requirements less than that of a simple current mirror is presented. These features are achieved with very simple structure avoiding extra large node impedances to ensure high bandwidth operation. The circuit's principle of operation is discussed and compared to simple and low voltage cascode (LVC) current mirrors. Such outstanding features of this current mirror as high output impedance ~384K, low input impedance~6.4, wide bandwidth~178MHz, low input voltage ~ 362mV, low output voltage ~ 38mV and low current transfer error ~4% (all at 50μA) makes it an outstanding choice for high performance applications. Simulation results in BSIM 0.35μm CMOS technology with HSPICE are given in comparison with simple, and LVC current mirrors to verify and validate the performance of the proposed current mirror.
Abstract: The fractal-shaped orifices are assumed to have a
significant effect on the pressure drop downstream pipe flow due to
their edge self-similarity shape which enhances the mixing
properties. Here, we investigate the pressure drop after these fractals
using a digital micro-manometer at different stations downstream a
turbulent flow pipe then a direct comparison has been made with the
pressure drop measured from regular orifices with the same flow
area. Our results showed that the fractal-shaped orifices have a
significant effect on the pressure drop downstream the flow. Also
the pressure drop measured across the fractal-shaped orifices is
noticed to be lower that that from ordinary orifices of the same flow
areas. This result could be important in designing piping systems
from point of view of losses consideration with the same flow
control area. This is promising to use the fractal-shaped orifices as
flowmeters as they can sense the pressure drop across them
accurately with minimum losses than the regular ones.
Abstract: The proper design of RF pulses in magnetic resonance imaging (MRI) has a direct impact on the quality of acquired images, and is needed for many applications. Several techniques have been proposed to obtain the RF pulse envelope given the desired slice profile. Unfortunately, these techniques do not take into account the limitations of practical implementation such as limited amplitude resolution. Moreover, implementing constraints for special RF pulses on most techniques is not possible. In this work, we propose to develop an approach for designing optimal RF pulses under theoretically any constraints. The new technique will pose the RF pulse design problem as a combinatorial optimization problem and uses efficient techniques from this area such as genetic algorithms (GA) to solve this problem. In particular, an objective function will be proposed as the norm of the difference between the desired profile and the one obtained from solving the Bloch equations for the current RF pulse design values. The proposed approach will be verified using analytical solution based RF simulations and compared to previous methods such as Shinnar-Le Roux (SLR) method, and analysis, selected, and tested the options and parameters that control the Genetic Algorithm (GA) can significantly affect its performance to get the best improved results and compared to previous works in this field. The results show a significant improvement over conventional design techniques, select the best options and parameters for GA to get most improvement over the previous works, and suggest the practicality of using of the new technique for most important applications as slice selection for large flip angles, in the area of unconventional spatial encoding, and another clinical use.
Abstract: The current trend of increasing quality and demands
of the final product is affected by time analysis of the entire
manufacturing process. The primary requirement of manufacturing is
to produce as many products as soon as possible, at the lowest
possible cost, but of course with the highest quality. Such
requirements may be satisfied only if all the elements entering and
affecting the production cycle are in a fully functional condition.
These elements consist of sensory equipment and intelligent control
elements that are essential for building intelligent manufacturing
systems. The intelligent manufacturing paradigm includes a new
approach to production system structure design. Intelligent behaviors
are based on the monitoring of important parameters of system and
its environment. The flexible reaction to changes. The realization and
utilization of this design paradigm as an "intelligent manufacturing
system" enables the flexible system reaction to production
requirement as soon as environmental changes too. Results of these
flexible reactions are a smaller layout space, be decreasing of
production and investment costs and be increasing of productivity.
Intelligent manufacturing system itself should be a system that can
flexibly respond to changes in entering and exiting the process in
interaction with the surroundings.
Abstract: This study was aimed for investigating of
manufacturing high aluminum content Mg alloys using a horizontal
twin roll caster. Recently, weight saving has been key issues for lighter
transport equipments as well as electronic component parts. As
alternative materials to aluminum alloys, developing magnesium alloy
with higher strength has been expected. Normally high Aluminum
content Mg alloy has poor ductility and is difficult to be rolled because
of its high strength. However, twin roll casting process is suitable for
manufacturing wrought Mg alloys because materials can be cast
directly from molten metal. In this study, manufacturing of high
aluminum content magnesium alloy sheet using the roll casting
process has been carried out. Effects of manufacturing parameter, such
as roll velocity, pouring temperature and roll gap, on casting was
investigated. A microscopic observation of the crystals of cross section
of as cast strip as well as rolled strip was conducted.
Abstract: The aim of this paper is to present current and future
procedures in castings procurement. Differences in procurement are
highlighted. The supplier selection criteria used in practice is
compared to literature findings. Different trends related to supply
chains are presented and it is described how they are reflected in
reality to castings procurement. To fulfil the aim, interviews were
conducted in nine companies using castings. It was found that largest
casting users have the most subcontractor foundries and it is more
typical that they have multiple suppliers for the same parts. Currently
only two companies out of nine purchase castings outside Europe,
but the others are also progressing in the same direction. The main
reason is the need to lower purchasing costs. Another trend is that all
companies want to buy cast components or sub-assemblies instead of
raw castings from foundries. It was found that price is a main
supplier selection criterion. All companies use competitive bidding in
supplier selection.
Abstract: This paper explores the scalability issues associated
with solving the Named Entity Recognition (NER) problem using
Support Vector Machines (SVM) and high-dimensional features. The
performance results of a set of experiments conducted using binary
and multi-class SVM with increasing training data sizes are
examined. The NER domain chosen for these experiments is the
biomedical publications domain, especially selected due to its
importance and inherent challenges. A simple machine learning
approach is used that eliminates prior language knowledge such as
part-of-speech or noun phrase tagging thereby allowing for its
applicability across languages. No domain-specific knowledge is
included. The accuracy measures achieved are comparable to those
obtained using more complex approaches, which constitutes a
motivation to investigate ways to improve the scalability of multiclass
SVM in order to make the solution more practical and useable.
Improving training time of multi-class SVM would make support
vector machines a more viable and practical machine learning
solution for real-world problems with large datasets. An initial
prototype results in great improvement of the training time at the
expense of memory requirements.
Abstract: Dynamic location referencing method is an important technology to shield map differences. These method references objects of the road network by utilizing condensed selection of its real-world geographic properties stored in a digital map database, which overcomes the defections existing in pre-coded location referencing methods. The high attributes completeness requirements and complicated reference point selection algorithm are the main problems of recent researches. Therefore, a dynamic location referencing algorithm combining intersection points selected at the extremities compulsively and road link points selected according to link partition principle was proposed. An experimental system based on this theory was implemented. The tests using Beijing digital map database showed satisfied results and thus verified the feasibility and practicability of this method.
Abstract: There have been many variations of technologies that helped educators in teaching & learning. From the past research it is evident that Information Technology significantly increases student participation and interactivity in the classrooms. This research started with a aim to find whether adoption of Wi-Fi environment by Malaysian Higher Educational Institutions (HEI) can benefit students and staff equally. The study was carried out in HEI-s of Klang Valley, Malaysia and the data is gathered through paper based surveys. A sample size of 237 units were randomly selected from 5 higher educational institutions in the Klang Valley using the Stratified Random sampling method and from the analysis of the data, it was found that the implementation of wireless technologies in HEIs have created lot of opportunities and also challenges.
Abstract: This paper presents an overview of the Ocean wave kinetic energy harvesting system. Energy harvesting is a concept by which energy is captured, stored, and utilized using various sources by employing interfaces, storage devices, and other units. Ocean wave energy harvesting in which the kinetic and potential energy contained in the natural oscillations of Ocean waves are converted into electric power. The kinetic energy harvesting system could be used for a number of areas. The main applications that we have discussed in this paper are to how generate the energy from Ocean wave energy (kinetic energy) to electric energy that is to eliminate the requirement for continual battery replacement.
Abstract: GSM has undoubtedly become the most widespread
cellular technology and has established itself as one of the most
promising technology in wireless communication. The next
generation of mobile telephones had also become more powerful and
innovative in a way that new services related to the user-s location
will arise. Other than the 911 requirements for emergency location
initiated by the Federal Communication Commission (FCC) of the
United States, GSM positioning can be highly integrated in cellular
communication technology for commercial use. However, GSM
positioning is facing many challenges. Issues like accuracy,
availability, reliability and suitable cost render the development and
implementation of GSM positioning a challenging task. In this paper,
we investigate the optimal mobile position tracking means. We
employ an innovative scheme by integrating the Kalman filter in the
localization process especially that it has great tracking
characteristics. When tracking in two dimensions, Kalman filter is
very powerful due to its reliable performance as it supports
estimation of past, present, and future states, even when performing
in unknown environments. We show that enhanced position tracking
results is achieved when implementing the Kalman filter for GSM
tracking.
Abstract: This paper is focused on issues of process modeling
and two model based control strategies of a fed-batch sugar
crystallization process applying the concept of artificial neural
networks (ANNs). The control objective is to force the operation into
following optimal supersaturation trajectory. It is achieved by
manipulating the feed flow rate of sugar liquor/syrup, considered as
the control input. The control task is rather challenging due to the
strong nonlinearity of the process dynamics and variations in the
crystallization kinetics. Two control alternatives are considered –
model predictive control (MPC) and feedback linearizing control
(FLC). Adequate ANN process models are first built as part of the
controller structures. MPC algorithm outperforms the FLC approach
with respect to satisfactory reference tracking and smooth control
action. However, the MPC is computationally much more involved
since it requires an online numerical optimization, while for the FLC
an analytical control solution was determined.
Abstract: Anti-allergic effects of royal jelly were evaluated in a human-like mouse model of atopic dermatitis. NC/Nga mice were cutaneously applied with royal jelly for 6 weeks. Royal jelly-treated mice exhibited lower levels of serum total immunoglobulin E in comparison with controls. We found that the treatment decreased (11% to the control) expression of mRNA for aquaporin-3, which is involved in the modulation of epidermal hydration. Microarray analysis revealed more than 10-fold changes in the expression of several genes, such as transglutaminase 2, repetin, and keratins. In normal human epidermal keratinocytes, royal jelly extract suppressed interleukin-8 elevation induced by TNF-α and interferon-γ, suggesting direct anti-inflammatory activity in keratinocytes. Collectively, topical application of royal jelly may be useful for amelioration of lesions and inflammation in atopic dermatitis.