Abstract: In the immunologic sense, clinical infection is a state
of failure of the immune system to combat the pathogenic weapon of
the bacteria invading the host. A motile gram negative vibroid
organism associated with marked mono and poly nuclear cell
responses was traced during the examination of a clinical material
from an infected common carp Cyprinus carpio. On primary plate
culture, growth was shown to be pure, dense population of an
Aeromonas-like colony morphotype. The pure isolate was found to
be; Aerobic, facultatively anaerobic, non-halophilic, grew at 0C, and
37C, oxidase positive utilizes glucose through fermentative pathway,
resist 0/129 and novobiocin, produces alanine and lysine
decarboxylases but non-producing ornithine dehydrolases. Tests for
the in vitro determinants of pathogenicity has shown to be; Betahaemolytic
onto blood agar, gelatinase, casienase and amylase
producer. Three in vivo determinants of pathogenicity were tested as,
the lethal dose fifty, the pathogenesis and pathogenicity. It was
evident that 0.1 milliliter of the causal bacterial cell suspension of a
density 1 x 107 CFU/ml injected intramuscularly into an average of
100gms fish toke five days incubation period, then at the day six
morbidity and mortality were initiated. LD50 was recorded at the day
12 post-infection. Use of an LD50 doses to study the pathogenicity,
reveals mononuclear and polynuclear cell responses, on examining
the stained direct films of the clinical materials from the
experimentally infected fish. Re-isolation tests confirm that the reisolant
is same. The course of the infection in natural case was shown
manifestation of; skin ulceration, haemorrhage and descaling. On
evisceration, the internal organs were shown; congestion in the
intestines, spleen and, air sacs. The induced infection showed a
milder form of these manifestations. The grading of the virulence of
this organism was virulent causing chronic course of infections as
indicated from the pathogenesis and pathogenicity studies. Thus the
infectious bacteria were consistent with Aeromonas hydrophila, and
the infection was chronic.
Abstract: More than 3000 plants of notable phyto-therapeutic
value grow in South Africa; these include Cissampelos capensis,
commonly known in Afrikaans as dawidjie or dawidjiewortel. C.
capensis is the most significant and popular medicinal plant used by
the Khoisan as well as other rural groups in the Western region of
South Africa. Its rhizomes are traditionally used to treat male fertility
problems. Yet, no studies have investigated the effects of this plant or
its extracts on human spermatozoa. Therefore, this study aimed at
investigating the effects of C. capensis rhizome extract (CRE)
fractions on ejaculated human spermatozoa in vitro. Spermatozoa
from a total of 77 semen samples were washed with human tubular
fluid medium supplemented with bovine serum albumin (HTF-BSA)
and incubated for 2 hours with 20 μg/ml progesterone (P4) followed
by incubation with different concentrations (0, 0.05, 0.5, 5, 50, 200
μg/ml) of fractionated CRE (F1=0% MeOH, F2=30% MeOH,
F3=60% MeOH and F4=100% MeOH) for 1.5 hours at 37°C. A
sample without addition of CRE fractions served as control. Samples
were analyzed for sperm motility, reactive oxygen species (ROS),
DNA-fragmentation, acrosome reaction and capacitation. Results
showed that F1 resulted in significantly higher values for ROS,
capacitation and hyper-activation compared to F2, F3, and F4 with
P4-stimulated samples generally having higher values. No significant
effect was found for the other parameters. In conclusion, alkaloids
present in F1 of CRE appear to have triggered sperm intrinsic ROS
production leading to sperm capacitation and acrosome reaction
induced by P4.
Abstract: For the music composer Myriam Marbe the musical
time and memory represent 2 (complementary) phenomena with
conclusive impact on the settlement of new musical ontologies.
Summarizing the most important achievements of the contemporary
techniques of composition, her vision on the microform presented in
The Concert for Daniel Kientzy, saxophone and orchestra transcends
the linear and unidirectional time in favour of a flexible, multivectorial
speech with spiral developments, where the sound substance
is auto(re)generated by analogy with the fundamental processes of
the memory. The conceptual model is of an archetypal essence, the
music composer being concerned with identifying the mechanisms of
the creation process, especially of those specific to the collective
creation (of oral tradition). Hence the spontaneity of expression,
improvisation tint, free rhythm, micro-interval intonation, coloristictimbral
universe dominated by multiphonics and unique sound
effects, hence the atmosphere of ritual, however purged by the
primary connotations and reprojected into a wonderful spectacular
space. The Concert is a work of artistic maturity and enforces respect,
among others, by the timbral diversity of the three species of
saxophone required by the music composer (baritone, sopranino and
alt), in Part III Daniel Kientzy shows the performance of playing two
saxophones concomitantly. The score of the music composer Myriam
Marbe contains a deeply spiritualized music, full or archetypal
symbols, a music whose drama suggests a real cinematographic
movement.
Abstract: The comprehensive CFD models have been used to
represent and study the heterogeneous combustion of biomass. In the
present work, the operation of a global flue gas circuit in the sugarcane
bagasse combustion, from wind boxes below primary air grate
supply, passing by bagasse insertion in swirl burners and boiler
furnace, to boiler bank outlet is simulated. It uses five different
meshes representing each part of this system located in sequence:
wind boxes and grate, boiler furnace, swirl burners, superheaters and
boiler bank. The model considers turbulence using standard k-ε,
combustion using EDM, radiation heat transfer using DTM with 16
ray directions and bagasse particle tracking represented by Schiller-
Naumann model. The results showed good agreement with expected
behavior found in literature and equipment design. The more detailed
results view in separated parts of flue gas system allows observing
some flow behaviors that cannot be represented by usual
simplifications like bagasse supply under homogeneous axial and
rotational vectors and others that can be represented using new
considerations like the representation of 26 thousand grate orifices by
144 rectangular inlets.
Abstract: In order to use bitumen in hot mix asphalt, it must
have specific characteristics. There are some methods to reach these
properties. Using polymer modifiers are one of the methods to
modify the bitumen properties. In this paper the effect of Styrene-
Butadiene-Rubber that is one of the bitumen polymer modifiers on
rheology properties of bitumen is studied. In this regard, the
rheological properties of base bitumen and the modified bitumen with
3, 4, and 5 percent of Styrene-Butadiene-Rubber (SBR) were
analysed. The results show that bitumen modified with 5 percent of
SBR has the best performance than the other samples.
Abstract: The concept of national security in Iran is a
permanently effective factor in acceptance or rejection of many
international obligations. These obligations had been defined
according to the type of legislation of Iran in many aspects.
Therefore, there are several treaties at international level which
requires Iran’s security to come in contact with obligations in these
treaties in a way that an obstacle to join to them and their passage in
parliament. This issue is a typical category which every country pays
attention to be accepted in treaties or to include their national
security in that treaties and also they can see the related treaties from
this perspective, but this issue that 'what is the concept of Iran’s
national security', and 'To what extent it is changed in recent years,
especially after Islamic Revolution' are important issues that can be
criticized. Thus, this study is trying to assess singed treaties from the
perspective of Iran’s national security according of the true meaning
of treaty and to investigate how the international treaties may be in
conflict with Iran’s national security.
Abstract: This paper is aimed at proposing a rhombus shaped
wearable fractal antenna for wireless communication systems. The
geometrical descriptors of the antenna have been obtained using
bacterial foraging optimization (BFO) for wide band operation. The
method of moment based IE3D software has been used to simulate
the antenna and observed that miniaturization of 13.08% has been
achieved without degrading the resonating properties of the proposed
antenna. An analysis with different substrates has also been done in
order to evaluate the effectiveness of electrical permittivity on the
presented structure. The proposed antenna has low profile, light
weight and has successfully demonstrated wideband and multiband
characteristics for wearable electronic applications.
Abstract: The grain quality of chickpea in Iran is low and
instable, which may be attributed to the evolution of cultivars with a
narrow genetic base making them vulnerable to biotic stresses. Four
chickpea varieties from diverse geographic origins were chosen and
arranged in a randomized complete block design. Mesorhizobium sp.
cicer strain SW7 was added to all the chickpea seeds. Chickpea seeds
were planted on October 9, 2013. Each genotype was sown 5 m in
length, with 35 cm inter-row spacing, in 3 rows. Weeds were
removed manually in all plots. Results showed that Analysis of
variance on the studied traits showed significant differences among
genotypes for N, P, K and Fe contents of chickpea, but there is not a
significant difference among Ca, Zn and Mg continents of chickpea.
The experimental coefficient of variation (CV) varied from 7.3 to
15.8. In general, the CV value lower than 20% is considered to be
good, indicating the accuracy of conducted experiments. The highest
grain N was observed in Hashem and Jam cultivars. The highest grain
P was observed in Jam cultivar. Phosphorus content (mg/100g)
ranged from 142.3 to 302.3 with a mean value of 221.3. The negative
correlation (-0.126) was observed between the N and P of chickpea
cultivars. The highest K and Fe contents were observed in Jam
cultivar.
Abstract: Kidney cancer is the most lethal urological cancer
accounting for 3% of adult malignancies. VHL, a tumor-suppressor
gene, is best known to be associated with renal cell carcinoma
(RCC). The VHL functions as negative regulator of hypoxia inducible
factors. Recent sequencing efforts have identified several novel
frequent mutations of histone modifying and chromatin remodeling
genes in ccRCC (clear cell RCC) including PBRM1 and SETD2. The
PBRM1 gene encodes the BAF180 protein, which involved in
transcriptional activation and repression of selected genes. SETD2
encodes a histone methyltransferase, which may play a role in
suppressing tumor development. In this study, RNAs of 30 paired
tumor and normal samples that were grouped according to the types
of kidney cancer and clinical characteristics of patients, including
gender and average age were examined by RT-PCR, SSCP and
sequencing techniques. VHL, PBRM1 and SETD2 expressions were
relatively down-regulated. However, statistically no significance was
found (Wilcoxon signed rank test, p>0.05). Interestingly, no mutation
was observed on the contrary of previous studies. Understanding the
molecular mechanisms involved in the pathogenesis of RCC has
aided the development of molecular-targeted drugs for kidney cancer.
Further analysis is required to identify the responsible genes rather
than VHL, PBRM1 and SETD2 in kidney cancer.
Abstract: The atmospheres in many cities along the coastal lines
in the world have been rapidly changed to coastal-industrial
atmosphere. Hence, it is vital to investigate the corrosion behavior of
steel exposed to this kind of environment. In this present study,
Electrochemical Impedance Spectrography (EIS) and film thickness
measurement were applied to monitor the corrosion behavior of
weathering steel covered with a thin layer of the electrolyte in a
wet-dry cyclic condition, simulating a coastal-industrial environment
at 25oC and 60% RH. The results indicate that in all cycles, the
corrosion rate increases during the drying process due to an increase in
anion concentration and an acceleration of oxygen diffusion enhanced
by the effect of the thinning out of the electrolyte. During the wet-dry
cyclic corrosion test, the long-term corrosion behavior of this steel
depends on the periods of exposure. Corrosion process is first
accelerated and then decelerated. The decelerating corrosion process is
contributed to the formation of the protective rust, favored by the
wet-dry cycle and the acid regeneration process during the rusting
process.
Abstract: Introduction: There are multiple social, individual and
cultural factors that influence an individual’s decision to adopt family
planning methods especially among non-users in patriarchal societies
like Pakistan. Non-users, if targeted efficiently, can contribute
significantly to country’s CPR. A research study showed that nonusers
if convinced to adopt lactational amenorrhea method can shift
to long term methods in future. Research shows that if non users are
targeted efficiently a 59% reduction in unintended pregnancies in
Saharan Africa and South-Central and South-East Asia is anticipated.
Methods: We did secondary data analysis on Pakistan
Demographic Heath Survey (2012-13) dataset. Use of contraception
(never-use/ever-use) was the outcome variable. At univariate level
Chi-square/Fisher Exact test was used to assess relationship of
baseline covariates with contraception use. Then variables to be
incorporated in the model were checked for multicollinearity,
confounding and interaction. Then binary logistic regression (with an
urban-rural stratification) was done to find relationship between
contraception use and baseline demographic and social variables.
Results: The multivariate analyses of the study showed that
younger women (≤ 29 years)were more prone to be never users as
compared to those who were >30 years and this trend was seen in
urban areas (AOR 1.92, CI 1.453-2.536) as well as rural areas (AOR
1.809, CI 1.421-2.303). While looking at regional variation, women
from urban Sindh (AOR 1.548, CI 1.142-2.099) and urban
Balochistan (AOR 2.403, CI 1.504-3.839) had more never users as
compared to other urban regions. Women in the rich wealth quintile
were more never users and this was seen both in urban and rural
localities (urban (AOR 1.106 CI .753-1.624); rural areas (AOR 1.162,
CI .887-1.524)) even though these were not statistically significant.
Women idealizing more children (>4) are more never users as
compared to those idealizing less children in both urban (AOR 1.854,
CI 1.275-2.697) and rural areas (AOR 2.101, CI 1.514-2.916).
Women who never lost a pregnancy were more inclined to be nonusers
in rural areas (AOR 1.394, CI 1.127-1.723) .Women familiar
with only traditional or no method had more never users in rural areas
(AOR 1.717, CI 1.127-1.723) but in urban areas it wasn’t significant.
Women unaware of Lady Health Worker’s presence in their area
were more never users especially in rural areas (AOR 1.276, CI
1.014-1.607). Women who did not visit any care provider were more
never users (urban (AOR 11.738, CI 9.112-15.121) rural areas (AOR
7.832, CI 6.243-9.826)).
Discussion/Conclusion: This study concluded that government,
policy makers and private sector family planning programs should
focus on the untapped pool of never users (younger women from underserved provinces, in higher wealth quintiles, who desire more
children.). We need to make sure to cover catchment areas where
there are less LHWs and less providers as ignorance to modern
methods and never been visited by an LHW are important
determinants of never use. This all is in sync with previous literate
from similar developing countries.
Abstract: This work sets out to debate the tensions involved in
the processes of contamination and self-purification in the urban
space, particularly in the streams that run through the Buenos Aires
metropolitan area. For much of their course, those streams are piped;
their waters do not come into contact with the outdoors until they
have reached deeply impoverished urban areas with high levels of
environmental contamination. These are peripheral zones that, until
thirty years ago, were marshlands and fields. They are now densely
populated areas largely lacking in urban infrastructure.
The Cárcova neighborhood, where this project is underway, is in
the José León Suárez section of General San Martín county, Buenos
Aires province. A stretch of José León Suarez canal crosses the
neighborhood. Starting upstream, this canal carries pollutants due to
the sewage and industrial waste released into it. Further downstream,
in the neighborhood, domestic drainage is poured into the stream. In
this paper, we formulate a hypothesis diametrical to the one that
holds that these neighborhoods are the primary source of
contamination, suggesting instead that in the stretch of the canal that
runs through the neighborhood the stream’s waters are actually
cleaned and the sediments accumulate pollutants. Indeed, the
stretches of water that runs through these neighborhoods act as water
processing plants for the metropolis.
This project has studied the different organic-load polluting
contributions to the water in a certain stretch of the canal, the
reduction of that load over the course of the canal, and the
incorporation of pollutants into the sediments. We have found that
the surface water has considerable ability to self-purify, mostly due to
processes of sedimentation and adsorption. The polluting load is
accumulated in the sediments where that load stabilizes slowly by
means of anaerobic processes. In this study, we also investigated the
risks of sediment management and the use of the processes studied
here in controlled conditions as tools of environmental restoration.
Abstract: Coal fly ash is formed as a solid waste product from
the combustion of coal in coal fired power stations. Huge amounts of
fly ash are produced globally every year and are predicted to
increase. Nowadays, less than half of the fly ash is used as a raw
material for cement manufacturing, construction and the rest of it is
disposed as a waste causing yet another environmental concern. For
this reason, the recycling of this kind of slurries into useful materials
is quite important in terms of economical and environmental aspects.
The purpose of this study is to evaluate the Orhaneli and
Tuncbilek coal fly ashes for utilization in some industrial
applications. Therefore the mineralogical and chemical compositions
of these fly ashes were analyzed by X-ray fluorescence spectroscopy,
ourier-transform infrared spectrometer, and X-ray diffraction. The
silicon (Si) and aluminum (Al) in the fly ashes were activated by
alkali fusion technique with sodium hydroxide. The obtained extracts
were analyzed for Si and Al content by inductively coupled plasma
optical emission spectrometry.
Abstract: The mechanisms underlying the association between
obesity and asthma may be related to a decreased immunological
tolerance induced by a defective function of regulatory T cells
(Tregs). The aim of this study is to establish the potential link
between these diseases and CD4+, CD25+ FoxP3+ Tregs as well as T
helper cells (Ths) in children. This is a prospective case control
study. Obese (n:40), asthmatic (n:40), asthmatic obese (n:40) and
healthy children (n:40), who don't have any acute or chronic diseases,
were included in this study. Obese children were evaluated according
to WHO criteria. Asthmatic patients were chosen based on GINA
criteria. Parents were asked to fill up the questionnaire. Informed
consent forms were taken. Blood samples were marked with CD4+,
CD25+ and FoxP3+ in order to determine Tregs and Ths by flow
cytometric method. Statistical analyses were performed. p≤0.05 was
chosen as meaningful threshold. Tregs exhibiting anti-inflammatory
nature were significantly lower in obese (0,16%; p≤0,001), asthmatic
(0,25%; p≤0,01) and asthmatic obese (0,29%; p≤0,05) groups than
the control group (0,38%). Ths were counted higher in asthma group
than the control (p≤0,01) and obese (p≤0,001) groups. T cell
immunity plays important roles in obesity and asthma pathogeneses.
Decreased numbers of Tregs found in obese, asthmatic and asthmatic
obese children may help to elucidate some questions in
pathophysiology of these diseases. For HOMA-IR levels, any
significant difference was not noted between control and obese
groups, but statistically higher values were found for obese
asthmatics. The values obtained in all groups were found to be below
the critical cut off points. This finding has made the statistically
significant difference observed between Tregs of obese, asthmatic,
obese asthmatic and control groups much more valuable. These
findings will be useful in diagnosis and treatment of these disorders
and future studies are needed. The production and propagation of
Tregs may be promising in alternative asthma and obesity treatments.
Abstract: Poly bag and mulch films for agricultural field caused
pose environmental problem due to the non-degradable plastics
wastes upon disposal. Thus, a degradable poly bag was designed with
hybrid sago starch (SS) and polyvinyl alcohol (PVA). Two Different
blended compositions of SS and PVA hybrid have been compounded.
Then, the hybrids blended are mixed with linear line density
polyethylene (LLDPE) resin to fabricate poly bag film through
conventional film blowing process. Samples of LLDPE, SS and PVA
hybrid film were exposed to UV light and soil burial. The weight
losses were determined during degradation process. Hybrid film by
degradation of starch was found to hydrolyze and hydroxyl groups
decrease on esterification upon exposure to soil burial and uv
radiation. It was found out that, the hybrid film for 60% of SS
composition showed greatest degradation in soil and UV radiation.
Abstract: The hydrodynamics and heat transfer characteristics
of a vaporized elongated bubble in a rectangular microchannel have
been simulated based on Cahn-Hilliard phase-field method. In the
simulations, the initially nucleated bubble starts growing as it comes
in contact with superheated water. The growing shape of the bubble
compared well with the available experimental data in the literature.
Abstract: Long Distance Truck Drivers (LDTDs) have been
found to be a high risk group in the spread of HIV/AIDS globally;
perhaps, due to their high Sexual Risk Behaviours (SRBs).
Interventions for reducing SRBs in trucking population have not been
fully exploited. A quasi-experimental control group pretest-posttest
design was used to assess the efficacy of psycho-education and
behavioural skills training in reducing SRBs among LDTDs. Sixteen
drivers rivers were randomly assigned into either experimental or
control groups using balloting technique. Questionnaire was used as
an instrument for data collection. Repeated measures t-test and
independent t-test were used to test hypotheses. Intervention had
significant effect on the SRBs among LDTDs at post-test (t{7}=
6.01, p
Abstract: Incineration of municipal solid waste (MSW) is one of
the key scopes in the global clean energy strategy. A computational
fluid dynamics (CFD) model was established in order to reveal these
features of the combustion process in a fixed porous bed of MSW.
Transporting equations and process rate equations of the waste bed
were modeled and set up to describe the incineration process,
according to the local thermal conditions and waste property
characters. Gas phase turbulence was modeled using k-ε turbulent
model and the particle phase was modeled using the kinetic theory of
granular flow. The heterogeneous reaction rates were determined
using Arrhenius eddy dissipation and the Arrhenius-diffusion
reaction rates. The effects of primary air flow rate and temperature in
the burning process of simulated MSW are investigated
experimentally and numerically. The simulation results in bed are
accordant with experimental data well. The model provides detailed
information on burning processes in the fixed bed, which is otherwise
very difficult to obtain by conventional experimental techniques.
Abstract: Groundwater inflow to the tunnels is one of the most
important problems in tunneling operation. The objective of this
study is the investigation of model dimension effects on tunnel inflow
assessment in discontinuous rock masses using numerical modeling.
In the numerical simulation, the model dimension has an important
role in prediction of water inflow rate. When the model dimension is
very small, due to low distance to the tunnel border, the model
boundary conditions affect the estimated amount of groundwater flow
into the tunnel and results show a very high inflow to tunnel. Hence,
in this study, the two-dimensional universal distinct element code
(UDEC) used and the impact of different model parameters, such as
tunnel radius, joint spacing, horizontal and vertical model domain
extent has been evaluated. Results show that the model domain extent
is a function of the most significant parameters, which are tunnel
radius and joint spacing.
Abstract: Generating random numbers are mainly used to create
secret keys or random sequences. It can be carried out by various
techniques. In this paper we present a very simple and efficient
pseudo random number generator (PRNG) based on chaotic maps
and S-Box tables. This technique adopted two main operations one to
generate chaotic values using two logistic maps and the second to
transform them into binary words using random S-Box tables.
The simulation analysis indicates that our PRNG possessing
excellent statistical and cryptographic properties.