Abstract: Candida spp. are common and aggressive pathogens.
Because of the growing resistance of Candida spp. to current
antifungals, novel targets, found in Candida spp. but not in humans
or other flora, have to be identified. The alternative oxidase (AOX)
is one such possibility. This enzyme is insensitive to cyanide, but is
sensitive to compounds such as salicylhydroxamic acid (SHAM),
disulfiram and n-alkyl gallates. The growth Candida albicans was
inhibited by SHAM (Ki = 9-15 mM) and cyanide (Ki = 2-4 mM),
albeit to differing extents. The rate of O2 uptake was inhibited by
less than 10% by 25 mM SHAM and by about 90% by 250 μM
KCN. Although SHAM substantially inhibited the growth of C.
albicans, it is unlikely that the inhibition of AOX was the cause.
Salicylhydroxamic acid is used therapeutically in the treatment of
urinary tract infections and urolithiasis, but it also has some potential
in the treatment of C. albicans infection.
Abstract: This paper presents the results of a comprehensive
investigation of five blackouts that occurred on 28 August to 8
September 2011 due to bushing failures of the 132/33 kV, 125 MVA
transformers at JBB Ali Grid station. The investigation aims to
explore the root causes of the bushing failures and come up with
recommendations that help in rectifying the problem and avoiding the
reoccurrence of similar type of incidents. The incident reports about
the failed bushings and the SCADA reports at this grid station were
examined and analyzed. Moreover, comprehensive power quality
field measurements at ten 33/11 kV substations (S/Ss) in JBB Ali
area were conducted, and frequency scans were performed to verify
any harmonic resonance frequencies due to power factor correction
capacitors. Furthermore, the daily operations of the on-load tap
changers (OLTCs) of both the 125 MVA and 20 MVA transformers
at JBB Ali Grid station have been analyzed. The investigation
showed that the five bushing failures were due to a local problem, i.e.
internal degradation of the bushing insulation. This has been
confirmed by analyzing the time interval between successive OLTC
operations of the faulty grid transformers. It was also found that
monitoring the number of OLTC operations can help in predicting
bushing failure.
Abstract: This paper considers the problem of Null-Steering beamforming using Neural Network (NN) approach for antenna array system. Two cases are presented. First, unlike the other authors, the estimated Direction Of Arrivals (DOAs) are used for antenna array weights NN-based determination and the imprecise DOAs estimations are taken into account. Second, the blind null-steering beamforming is presented. In this case the antenna array outputs are presented at the input of the NN without DOAs estimation. The results of computer simulations will show much better relative mean error performances of the first NN approach compared to the NNbased blind beamforming.
Abstract: This paper describes the shape optimization of impeller
blades for a anti-heeling bidirectional axial flow pump used in ships.
In general, a bidirectional axial pump has an efficiency much lower
than the classical unidirectional pump because of the symmetry of the
blade type. In this paper, by focusing on a pump impeller, the shape of
blades is redesigned to reach a higher efficiency in a bidirectional axial
pump. The commercial code employed in this simulation is CFX v.13.
CFD result of pump torque, head, and hydraulic efficiency was
compared. The orthogonal array (OA) and analysis of variance
(ANOVA) techniques and surrogate model based optimization using
orthogonal polynomial, are employed to determine the main effects
and their optimal design variables. According to the optimal design,
we confirm an effective design variable in impeller blades and explain
the optimal solution, the usefulness for satisfying the constraints of
pump torque and head.
Abstract: Due to the emergence of “Humanized Healthcare"
introduced by Professor Dr. Prawase Wasi in 2003[1], the
development of this paradigm tends to be widely implemented. The
organizations included Healthcare Accreditation Institute (public
organization), National Health Foundation, Mahidol University in
cooperation with Thai Health Promotion Foundation, and National
Health Security Office (Thailand) have selected the hospitals or
infirmaries that are qualified for humanized healthcare since 2008-
2010 and 35 of them are chosen to be the outstandingly navigating
organizations for the development of humanized healthcare,
humanized healthcare award [2].
The research aims to study the current issue, characteristics and
patterns of hospital administration contributing to humanized
healthcare system in Thailand. The selected case studies are from
four hospitals including Dansai Crown Prince Hospital, Leoi;
Ubolrattana Hospital, Khon Kaen; Kapho Hospital, Pattani; and
Prathai Hospital, Nakhonrachasima. The methodology is in-depth
interviewing with 10 staffs working as hospital executive directors,
and representatives from leader groups including directors,
multidisciplinary hospital committees, personnel development
committees, physicians and nurses in each hospital. (Total=40) In
addition, focus group discussions between hospital staffs and general
people (including patients and their relatives, the community leader,
and other people) are held by means of setting 4 groups including 8
people within each group. (Total=128) The observation on the
working in each hospital is also implemented. The findings of the
study reveal that there are five important aspects found in each
hospital including (1) the quality improvement under the mental and
spiritual development policy from the chief executives and lead
teams, leaders as Role model and they have visionary leadership; (2)
the participation hospital administration system focusing on learning
process and stakeholder- needs, spiritual human resource
management and development; (3) the relationship among people
especially staffs, team work skills, mutual understanding, effective
communication and personal inner-development; (4) organization
culture relevant to the awareness of patients- rights as well as the
participation policy including spiritual growth achieving to the same
goals, sharing vision, developing public mind, and caring; and (5)
healing structures or environment providing warmth and convenience
for hospital staffs, patients and their relatives and visitors.
Abstract: In this study, inhibition of Microcystis aeruginosa by
antialgal alleochemical gramine, was studied by analyzing algal
metabolic activity (represented by esterase and total dehydrogenase
activities) and cell ultrastructure (showing morphological and
ultrastructure alterations using transmission electron microscopy and
DNA ladder analysis). After gramine exposure, esterase and total
dehydrogenase activities were increased firstly but decreased later. In
contrast with the controls, the cells exposed to gramine showed
apparent ultrastructure alterations with thylakoids in breakage,
phycobilins in decrease, lipid and cyanophycin granules abundant
firstly but dissolved afterwards, DNA in fragementation. The
occurrence of increase of metabolic activity and specific granules
reflected that the resistance of cellular response to gramine was
initiated. DNA fragementation associated with the increase of
metabolic activity and specific granules hinted that gramine caused M.
aeruginosa cells to initiate some morphotype of programmed cell
death.
Abstract: Positioning the organization in the strategic
environment of its industry is one of the first and most important
phases of the organizational strategic planning and in today
knowledge-based economy has its importance been duplicated for
higher education institutes as the centers of education, knowledge
creation and knowledge worker training. Up to now, various models
with diverse approaches have been applied to investigate
organizations- strategic position in different industries. Regarding the
essential importance and strategic role of quality in higher education
institutes, in this study, a quality-oriented approach has been
suggested to positioning them in their strategic environment. Then
the European Foundation of Quality Management (EFQM) model has
been adopted to position the top Iranian business schools in their
strategic environment. The result of this study can be used in strategic
planning of these institutes as well as the other Iranian business
schools.
Abstract: This paper presents a new method of fault detection and isolation (FDI) for polymer electrolyte membrane (PEM) fuel cell (FC) dynamic systems under an open-loop scheme. This method uses a radial basis function (RBF) neural network to perform fault identification, classification and isolation. The novelty is that the RBF model of independent mode is used to predict the future outputs of the FC stack. One actuator fault, one component fault and three sensor faults have been introduced to the PEMFC systems experience faults between -7% to +10% of fault size in real-time operation. To validate the results, a benchmark model developed by Michigan University is used in the simulation to investigate the effect of these five faults. The developed independent RBF model is tested on MATLAB R2009a/Simulink environment. The simulation results confirm the effectiveness of the proposed method for FDI under an open-loop condition. By using this method, the RBF networks able to detect and isolate all five faults accordingly and accurately.
Abstract: In two studies we tested the hypothesis that the
appropriate linguistic formulation of a deontic rule – i.e. the
formulation which clarifies the monadic nature of deontic operators
- should produce more correct responses than the conditional
formulation in Wason selection task. We tested this assumption by
presenting a prescription rule and a prohibition rule in conditional
vs. proper deontic formulation. We contrasted this hypothesis with
two other hypotheses derived from social contract theory and
relevance theory. According to the first theory, a deontic rule
expressed in terms of cost-benefit should elicit a cheater detection
module, sensible to mental states attributions and thus able to
discriminate intentional rule violations from accidental rule
violations. We tested this prevision by distinguishing the two types
of violations. According to relevance theory, performance in
selection task should improve by increasing cognitive effect and
decreasing cognitive effort. We tested this prevision by focusing
experimental instructions on the rule vs. the action covered by the
rule. In study 1, in which 480 undergraduates participated, we
tested these predictions through a 2 x 2 x 2 x 2 (type of the rule x
rule formulation x type of violation x experimental instructions)
between-subjects design. In study 2 – carried out by means of a 2 x
2 (rule formulation x type of violation) between-subjects design -
we retested the hypothesis of rule formulation vs. the cheaterdetection
hypothesis through a new version of selection task in
which intentional vs. accidental rule violations were better
discriminated. 240 undergraduates participated in this study.
Results corroborate our hypothesis and challenge the contrasting
assumptions. However, they show that the conditional formulation
of deontic rules produces a lower performance than what is
reported in literature.
Abstract: This paper presents the results of an analytical study
on the seismic response of a Multi-Span-Simply-Supported precast
bridge in Washington State. The bridge was built in the early 1960's
along Interstate 5 and was widened the first time in 1979 and the
second time in 2001. The primary objective of this research project
is to determine the seismic vulnerability of the bridge in order to
develop the required retrofit measure. The seismic vulnerability of
the bridge is evaluated using two seismic evaluation methods
presented in the FHWA Seismic Retrofitting Manual for Highway
Bridges, Method C and Method D2. The results of the seismic
analyses demonstrate that Method C and Method D2 vary markedly
in terms of the information they provide to the bridge designer
regarding the vulnerability of the bridge columns.
Abstract: In this paper, an analytical approach for free vibration
analysis of four edges simply supported rectangular Kirchhoff plates
is presented. The method is based on wave approach. From wave
standpoint vibration propagate, reflect and transmit in a structure.
Firstly, the propagation and reflection matrices for plate with simply
supported boundary condition are derived. Then, these matrices are
combined to provide a concise and systematic approach to free
vibration analysis of a simply supported rectangular Kirchhoff plate.
Subsequently, the eigenvalue problem for free vibration of plates is
formulated and the equation of plate natural frequencies is
constructed. Finally, the effectiveness of the approach is shown by
comparison of the results with existing classical solution.
Abstract: The present work demonstrates the design and simulation of a fuzzy control of an air conditioning system at different pressures. The first order Sugeno fuzzy inference system is utilized to model the system and create the controller. In addition, an estimation of the heat transfer rate and water mass flow rate injection into or withdraw from the air conditioning system is determined by the fuzzy IF-THEN rules. The approach starts by generating the input/output data. Then, the subtractive clustering algorithm along with least square estimation (LSE) generates the fuzzy rules that describe the relationship between input/output data. The fuzzy rules are tuned by Adaptive Neuro-Fuzzy Inference System (ANFIS). The results show that when the pressure increases the amount of water flow rate and heat transfer rate decrease within the lower ranges of inlet dry bulb temperatures. On the other hand, and as pressure increases the amount of water flow rate and heat transfer rate increases within the higher ranges of inlet dry bulb temperatures. The inflection in the pressure effect trend occurs at lower temperatures as the inlet air humidity increases.
Abstract: A Rotary Disc Contactor with inner diameter of
9.1cm and maximum operating height of 40cm has been used to
investigate break up phenomenon. Water-Toluene, Water as
continuous phase and Toluene as dispersed phase, was selected as
chemical system in the experiments. The mentioned chemical system
has high interfacial tension so it was possible to form big drops
which permit accurate investigation on break up phenomenon as well
as the first and second critical rotor speeds.
In this study, Break up phenomenon has been studied as a function
of mother drop size, rotor speed and continuous phase height. Further
more; the effects of mother drop size and continuous phase height on
the first and second critical rotor speeds were investigated. Finally,
two modified correlations were proposed to estimate the first and
second critical speeds.
Abstract: Random Oracle Model (ROM) is an effective method
for measuring the practical security of cryptograph. In this paper, we
try to use it into information hiding system (IHS). Because IHS has its
own properties, the ROM must be modified if it is used into IHS.
Firstly, we fully discuss why and how to modify each part of ROM
respectively. The main changes include: 1) Divide the attacks that IHS
may be suffered into two phases and divide the attacks of each phase
into several kinds. 2) Distinguish Oracles and Black-boxes clearly. 3)
Define Oracle and four Black-boxes that IHS used. 4) Propose the
formalized adversary model. And 5) Give the definition of judge.
Secondly, based on ROM of IHS, the security against known original
cover attack (KOCA-KOCA-security) is defined. Then, we give an
actual information hiding scheme and prove that it is
KOCA-KOCA-secure. Finally, we conclude the paper and propose the
open problems of further research.
Abstract: Scatter behavior of fatigue life in die-cast AM60B
alloy was investigated. For comparison, those in rolled AM60B alloy
and die-cast A365-T5 aluminum alloy were also studied. Scatter
behavior of pore size was also investigated to discuss dominant
factors for fatigue life scatter in die-cast materials. Three-parameter
Weibull function was suitable to explain the scatter behavior of both
fatigue life and pore size. The scatter of fatigue life in die-cast
AM60B alloy was almost comparable to that in die-cast A365-T5
alloy, while it was significantly large compared to that in the rolled
AM60B alloy. Scatter behavior of pore size observed at fracture
nucleation site on the fracture surface was comparable to that
observed on the specimen cross-section and also to that of fatigue
life. Therefore, the dominant factor for large scatter of fatigue life in
die-cast alloys would be the large scatter of pore size. This
speculation was confirmed by the fracture mechanics fatigue life
prediction, where the pore observed at fatigue crack nucleation site
was assumed as the pre-existing crack.
Abstract: In this paper first, Two buildings have been modeled
and then analyzed using nonlinear static analysis method under two
different conditions in Nonlinear SAP 2000 software. In the first
condition the interaction of soil adjacent to the walls of basement are
ignored while in the second case this interaction have been modeled
using Gap elements of nonlinear SAP2000 software. Finally,
comparing the results of two models, the effects of soil-structure on
period, target point displacement, internal forces, shape deformations
and base shears have been studied. According to the results, this
interaction has always increased the base shear of buildings,
decreased the period of structure and target point displacement, and
often decreased the internal forces and displacements.
Abstract: Wavelet transform provides several important
characteristics which can be used in a texture analysis and
classification. In this work, an efficient texture classification method,
which combines concepts from wavelet and co-occurrence matrices,
is presented. An Euclidian distance classifier is used to evaluate the
various methods of classification. A comparative study is essential to
determine the ideal method. Using this conjecture, we developed a
novel feature set for texture classification and demonstrate its
effectiveness
Abstract: In wireless sensor network (WSN) the use of mobile
sink has been attracting more attention in recent times. Mobile sinks
are more effective means of balancing load, reducing hotspot
problem and elongating network lifetime. The sensor nodes in WSN
have limited power supply, computational capability and storage and
therefore for continuous data delivery reliability becomes high
priority in these networks. In this paper, we propose a Reliable
Energy-efficient Data Dissemination (REDD) scheme for WSNs with
multiple mobile sinks. In this strategy, sink first determines the
location of source and then directly communicates with the source
using geographical forwarding. Every forwarding node (FN) creates a
local zone comprising some sensor nodes that can act as
representative of FN when it fails. Analytical and simulation study
reveals significant improvement in energy conservation and reliable
data delivery in comparison to existing schemes.
Abstract: The dome with ribs and rings, which covers the
ROMEXPO pavilion from Bucharest, was designed after the collapse
of the single layer reticulated dome. In this paper, it was made the
checking of the structure, under the dynamic loads with three
recorded accelerograms calibrated according to Romanian seismic
design code P100-1/2006. Under the action the dynamic loadings, it
was made a time-history analysis to determine the zones where the
plastic hinges appear, at what accelerations and their position on the
structure. The studied dome is formed by 32 spatial semi arches and
three rings: one circular ring located at the top of the dome and
another two rings, design as trusses, the first near the supports and the
second as an intermediate rings above the skylights. Above the
skylights up to the top, the dome is tight together with purlins and
bracings.
Abstract: The process of constructing a scale measuring the attitudes of youth toward violence on televisions is reported. A 30-item draft attitude scale was applied to a working group of 232 students attending the Faculty of Educational Sciences at Ankara University between the years 2005-2006. To introduce the construct validity and dimensionality of the scale, exploratory and confirmatory factor analysis was applied to the data. Results of the exploratory factor analysis showed that the scale had three factors that accounted for 58,44% (22,46% for the first, 22,15% for the second and 13,83% for the third factor) of the common variance. It is determined that the first factor considered issues related individual effects of violence on televisions, the second factor concerned issues related social effects of violence on televisions and the third factor concerned issues related violence on television programs. Results of the confirmatory factor analysis showed that all the items under each factor are fitting the concerning factors structure. An alpha reliability of 0,90 was estimated for the whole scale. It is concluded that the scale is valid and reliable.