Abstract: New graph similarity methods have been proposed in this work with the aim to refining the chemical information extracted from molecules matching. For this purpose, data fusion of the isomorphic and nonisomorphic subgraphs into a new similarity measure, the Approximate Similarity, was carried out by several approaches. The application of the proposed method to the development of quantitative structure-activity relationships (QSAR) has provided reliable tools for predicting several pharmacological parameters: binding of steroids to the globulin-corticosteroid receptor, the activity of benzodiazepine receptor compounds, and the blood brain barrier permeability. Acceptable results were obtained for the models presented here.
Abstract: The aspiration of this research article is to target and
focus the gains of university-Industry (U-I) collaborations and
exploring those hurdles which are the obstacles for attaining these
gains. University-Industry collaborations have attained great
importance since 1980 in USA due to its application in all fields of
life. U-I collaboration is a bilateral process where academia is a
proactive member to make such alliances. Universities want to
ameliorate their academic-base with the technicalities of technobabbles.
U-I collaboration is becoming an essential lane for achieving
innovative goals in this century. Many developed nations have set
successful examples to prove this phenomenon as a catalyst to reduce
costs, efforts and personnel for R&D projects. This study is exploits
amplitudes of UI collaboration incentives in the light of success
stories of developed countries. Many universities in USA, UK,
Canada and various European Countries have been engaged with
enterprises for numerous collaborative agreements. A long list of
strategic and short term R&D projects has been executed in
developed countries to accomplish their intended purposes. Due to
the lack of intentions, genuine research and research-oriented
environment, the mentioned field could not grow very well in
developing countries. During last decade, a new wave of research
has induced the institutes of developing countries to promote R&D
culture especially in Pakistan. Higher Education Commission (HEC)
has initiated many projects and funding supports for universities
which have collaborative intentions with industry.
Findings show that rapid innovation, overwhelm the technological
complexities and articulated intellectual-base are major incentives
which steer both partners to establish faculty-industry alliances. Everchanging
technologies, concerned about intellectual property,
different research environment and culture, research relevancy (Basic
or applied), exposure differences and diversity of knowledge
(bookish or practical) are main barriers to establish and retain joint
ventures. Findings also concluded that, it is dire need to support and
enhance cooperation among academia and industry to promote highly
coordinated research behaviors. Author has proposed a roadmap for
developing countries to promote R&D clusters among faculty and
industry to deal the technological challenges and innovation
complexities. Based on our research findings, Model for R&D
Collaboration for developing countries also have been proposed to
promote articulated R&D environment. If developing countries
follow this phenomenon, rapid innovations can be achieved with
limited R&D budget heads.
Abstract: The search for competitive advantages as one of the
main activities of a company has become a principle of contemporary
theories on Strategic Management. Innovation facilitates a company's
adaptation to the global competitive environment, representing the
important strategic role that it has to play in relation to managerial
performance and, as such, underlines the growing importance of
innovation and the use of a company's technological assets. This
paper therefore studies the effect in the results of four dimensions of
technological innovation strategy on a sample of Spanish wineries,
situated in the Castilla La-Mancha region of Spain, all of which are
registered under the La Mancha Designation of Origin (DO).
Abstract: In order to study the effects of supplemental irrigation, different levels of nitrogen chemical fertilizer and inoculation with rhizobium bacteria on the grain yield of chickpea, an experiment was carried out using split plot arrangement in randomize complete block design with three replication in agricultural researches station of Zanjan, Iran during 2009-2010 cropping season. The factors of experiment consisted of irritation (without irrigation (I1), irrigation at flowering stage (I2), irrigation at flowering and grain filling stages (I3) and full irrigation (I4)) and different levels of nitrogen fertilizer (without using of nitrogen fertilizer (N0), 75 kg.ha-1 (N75), 150 kg.ha-1 (N150) and inoculation with rhizobium bacteria (N4). The results of the analysis of variance showed that the effects of irrigation, nitrogen fertilizer levels and bacterial inoculation, were significant affect on number of pods per plant, number grains per plant, grain weight, grain yield, biological yield and harvest index at 1% probability level. Also Results showed that the grain yield in full irrigation treatment and inoculated with rhizobium bacteria was significantly higher than the other treatments.
Abstract: Dew harvesting needs only weak investment and
exploits a free, clean and inexhaustible energy. This study aims to
measure the relative contributions of dew and rain water in the
Mediterranean Dalmatian coast and islands of Croatia and determine
whether dew water is potable. Two sites were chosen, an open site on
the coast favourable to dew formation (Zadar) and a less favourable
site in a circus of mountains in Komiža (Vis Island). Between July
1st, 2003 and October 31st, 2006, dew hasbeen daily collected on a 1
m2 tilted (30°) test dew condenser together with ordinary
meteorological data (air temperature and relative humidity, cloud
coverage, windspeed and direction). The mean yearly cumulative
dew yields were found to be 20 mm (Zadar) and 9.3 mm (Komiža ).
During the dry season (May to October), monthly cumulative dew
water yield can represent up to 38% of water collected by rain fall. In
July 2003 and 2006, dew water represented about 120% of the
monthly cumulative rain water. Dew and rain water were analyzed in
Zadar. The corresponding parameters were measured: pH, electrical
conductivity, major anions (HCO3
-, Cl-, SO4
2-
, NO3
-
, ,) and major
cations (NH4
+, Na+, K+, Ca2+, Mg2+. Both dew and rain water are in
conformity with the WHO directives for potability except Mg2+.
Using existing roofs and refurbishing the abandoned impluviums to
permit dew collection could then provide a useful supplementary
amount of water, especially during the dry season.
Abstract: The aim of current research was to investigate ASLT method suitability for accelerated beer shelf-life determination. The research was accomplished on popular Latvian beer: light filtrated and unfiltered pasteurized beer with alcohol content 5.2%; dark filtrated pasteurized beer with alcohol content 4.2% with shelf-life five months. Bottled in dark glass bottles beer samples were storage during 20 weeks at several temperature regimes: +10±1 °C, +20±1 °C, +30±1 °C, +40±1 °C. Samples quality parameters as physically-chemical and microbiological was tested every two weeks using standard methods. It is possible to determine beer shelf-life rapidly during storage at +30±1 °C for filtered pasteurized light beer by 2.5 times, unfiltered pasteurized light beer by 1.4 times and for filtered pasteurized dark beer by 1.7 times. During preset experiments it was proved, that it is possible to determine beer shelf-life rapidly using ASLT method if beer storage temperature could be increased by +10±1 °C.
Abstract: Professional development is the focus of this study. It
reports on questionnaire data that examined the perceived
effectiveness of the Train the Trainer model of technology
professional development for elementary teachers. Eighty-three
selected teachers called Information Technology Coaches received
four half-day and one after-school in-service sessions. Subsequently,
coaches shared the information and skills acquired during training
with colleagues. Results indicated that participants felt comfortable
as Information Technology Coaches and felt well prepared because
of their technological professional development. Overall, participants
perceived the Train the Trainer model to be effective. The outcomes
of this study suggest that the use of the Train the Trainer model, a
known professional development model, can be an integral and
interdependent component of the newer more comprehensive
learning community professional development model.
Abstract: In this investigation, the antibacterial effects of
ethanolic and 7:3 isopropyl –hexane mixture extracts of Zingiber
officinale were evaluated against three Gram positive bacteria, B.
cereus, S.epidermidis, S. aureus and three Gram negative bacteria, E.
coli, K.pneumonia and P.areuginosa. Utilizing paper disk diffusion
and well methods in-vitro, MIC and MBC were determined by
macrodilution. The results showed that ethanolic rhizome extract of
ginger had significantly active than Isopropyl –hexan extract. Further
work needs to be done in these extracts including fractionation to
isolate active constituents and subsequent pharmacological
evaluation.
Abstract: The possible therapeutic effect of cannabidiol, the major non-psychotropic Cannabis constituent, was investigated against acute hepatotoxicity induced by a single oral dose of acetaminophen (500mg/kg) in mice. Cannabidiol (two intraperitoneal injections, 5mg/kg, each) was given 1 hour and 12 hours following acetaminophen administration. Acetaminophen administration caused significant elevations of serum alanine aminotransferase, and hepatic malondialdehyde, and nitric oxide levels, and a significant decrease in hepatic reduced glutathione. Cannabidiol significantly attenuated the deterioration in the measured biochemical parameters resulted from acetaminophen administration. Also, histopathological examination showed that cannabidiol markedly attenuated ameliorated acetaminophen-induced liver tissue damage. These results emphasize that cannabidiol represents a potential therapeutic option to protect against acetaminophen hepartotoxicity which is a common clinical problem.
Abstract: The distillation process in the general sense is a
relatively simple technique from the standpoints of its principles.
When dedicating distillation to water treatment and specifically
producing fresh water from sea, ocean and/ briny waters it is
interesting to notice that distillation has no limitations or domains of
applicability regarding the nature or the type of the feedstock water.
This is not the case however for other techniques that are
technologically quite complex, necessitate bigger capital investments
and are limited in their usability. In a previous paper we have
explored some of the effects of temperature on yield. In this paper,
we continue building onto that knowledge base and focus on the
effects of several additional engineering and design variables on
productivity.
Abstract: Climate change and environmental pressures are
major international issues nowadays. It is time when governments,
businesses and consumers have to respond through more
environmentally friendly and aware practices, products and policies.
This is the prime time to develop alternative sustainable construction
materials, reduce greenhouse gas emissions, save energy, look to
renewable energy sources and recycled materials, and reduce waste.
The utilization of waste materials (slag, fly ash, glass beads, plastic
and so on) in concrete manufacturing is significant due to its
engineering, financial, environmental and ecological benefits. Thus,
utilization of waste materials in concrete production is very much
helpful to reach the goal of the sustainable construction. Therefore,
this study intends to use glass beads in concrete production.
The paper reports on the performance of 9 different concrete
mixes containing different ratios of glass crushed to 5 mm - 20 mm
maximum size and glass marble of 20 mm size as coarse aggregate.
Ordinary Portland cement type 1 and fine sand less than 0.5 mm were
used to produce standard concrete cylinders. Compressive strength
tests were carried out on concrete specimens at various ages. Test
results indicated that the mix having the balanced ratio of glass beads
and round marbles possess maximum compressive strength which is
3889 psi, as glass beads perform better in bond formation but have
lower strength, on the other hand marbles are strong in themselves
but not good in bonding. These mixes were prepared following a
specific W/C and aggregate ratio; more strength can be expected to
achieve from different W/C, aggregate ratios, adding admixtures like
strength increasing agents, ASR inhibitor agents etc.
Abstract: Asphalt surfaces are exposed to various weather
conditions and dynamic loading caused by passing trucks and
vehicles. In such situations, asphalt cement shows so different
rheological-mechanical behavior. If asphalt cement isn-t compatible
enough, asphalt layer will be damaged immediately and expensive
repairing procedures should be performed then. To overcome this
problem, researchers study on mechanical improved asphalt cement.
In this study, bentonite was used in order to modify bitumen
characteristics and the modified bitumen's characteristics were
investigated by asphalt cement tests. Then, the optimal bitumen
content in various compounds was determined and asphalt samples
with different contents of additives were prepared and tested. Results
show using this kind of additive not only has caused improvement in
bitumen mechanical properties, but also improvement in Marshall
Parameters was achieved.
Abstract: Internet application in China has maintained a constant
development tendency in the past decade. China is now one of the
most populous countries in terms of internet user population. While
offering enormous opportunities, the dramatic digitalization also
brings about a series of challenges that demand urgent attention.
Digital divide is one of the challenges that affect China as well as other
countries in the world. This paper examines digital divide in the
Chinese context from the perspective of development communication.
Through a case study of a rural township under the backdrop of the
rapid internet development in China, the paper discusses the
economic, psychological and cultural roots of digital divide; and
explores development communication strategies addressing the roots
of digital divide. It is argued that development communication must be
responsive to the potentialities and preferences of the specific society
and serve the purposes of participation and sustainability.
Abstract: This article explores the self-identity of the Kazakh
people by way of identifying the roots of self-understanding in
Kazakh culture. Unfortunately, Western methods of ethno
psychology cannot fully capture what is unique about identity in
Kazakh culture. Although Kazakhstan is the ninth largest country in
terms of geographical space, Kazakh cultural identity is not wellknown
in the West. In this article we offer an account of the national
psychological features of the Kazakh people, in order to reveal the
spiritual, mental, ethical dimensions of modern Kazakhs. These
factors play a central role in the revival of forms of identity that are
central to the Kazakh people.
Abstract: This communication is intended to provide some issues for thought on the importance of implementation of Blended Learning in traditional universities, particularly in the Spanish university system. In this respect, we believe that virtual environments are likely to meet some of the needs raised by the Bologna agreement, trying to maintain the quality of teaching and at the same time taking advantage of the functionalities that virtual learning platforms offer. We are aware that an approach of learning from an open and constructivist nature in universities is a complex process that faces significant technological, administrative and human barriers. Therefore, in order to put plans in our universities, it is necessary to analyze the state of the art of some indicators relating to the use of ICT, with special attention to virtual teaching and learning, so that we can identify the main obstacles and design adaptive strategies for their full integration in the education system. Finally, we present major initiatives launched in the European and state framework for the effective implementation of new virtual environments in the area of higher education.
Abstract: An attempt has been made to develop a
seminumerical model to study temperature variations in dermal
layers of human limbs. The model has been developed for two
dimensional steady state case. The human limb has been assumed to
have elliptical cross section. The dermal region has been divided
into three natural layers namely epidermis, dermis and subdermal
tissues. The model incorporates the effect of important physiological
parameters like blood mass flow rate, metabolic heat generation, and
thermal conductivity of the tissues. The outer surface of the limb is
exposed to the environment and it is assumed that heat loss takes
place at the outer surface by conduction, convection, radiation, and
evaporation. The temperature of inner core of the limb also varies at
the lower atmospheric temperature. Appropriate boundary conditions
have been framed based on the physical conditions of the problem.
Cubic splines approach has been employed along radial direction and
Fourier series along angular direction to obtain the solution. The
numerical results have been computed for different values of
eccentricity resembling with the elliptic cross section of the human
limbs. The numerical results have been used to obtain the
temperature profile and to study the relationships among the various
physiological parameters.
Abstract: Khatunabad area is situated geologically in Urmieh-
Dokhtar magmatic belt in NW of Iran. In this research, studied area
has been investigated in order to recognize the potential copper and
molybdenum-bearing target areas. The survey layers include the
lithologic units, alteration, geochemical result, tectonics and copper
and molybdenum occurrence. As an accurate decision can have a
considerable effect on exploration plans, so in this efforts have been
made to make use of new combination method. For this purpose, the
analytical hierarchy process was used and revealed highly potential
copper and molybdenum mineralization areas. Based on achieved
results, geological perspective in north of studied area is appropriate
for advance stage, especially for subsurface exploration in future.
Abstract: Globin superfamily proteins including myoglobin and
hemoglobin, have welcome new members recently, namely,
cytoglobin, neuroglobin and globin X, though their physiological
functions are still to be addressed. Fish are the excellent models for the
study of these globins, but their characteristics have not yet been
discussed to date. In the present study, attempts have been made to
characterize their structural uniqueness by making use of proteomics
approach. This is the first comparative study on the characterization of
globin superfamily proteins from fish.
Abstract: Aggression is a behavior that cannot be approved by
the society. Vandalism which is aggression towards objects is an
action that tends to damage public or personal property. The
behaviors that are described as vandalism can often be observed in
the schools as well. According to Zwier and Vaughan (1)
previous research about the reasons of and precautionary measures
for vandalism in schools can be grouped in three tendency categories:
conservative, liberal and radical. In this context, the main aim of this
study is to discover which ideological tendency of the reasons of
school vandalism is adopted by the teachers and what are their
physical, environmental, school system and societal solutions for
vandalism. A total of 200 teachers participated in this study, and the
mean age was 34.20 years (SD = 6.54). The sample was made up of
109 females and 91 males. For the analysis of the data, SPSS 15.00,
frequency, percentage, and t-test were used. The research showed
that the teachers have tendencies in the order of conservative, liberal
and radical for the reasons of vandalism. The research also showed
that the teachers do not have any tendency for eliminating vandalism
physically and general solutions on the level of society; on the other
hand they mostly adopt a conservative tendency in terms of
precautions against vandalism in the school system. Second most,
they adopt the liberal tendency in terms of precautions against
vandalism in the school system. . It is observed that the findings of
this study are comparable to the existing literature on the subject.
Future studies should be conducted with multiple variants and
bigger sampling.
Abstract: Run-offs are considered as important hydrological factors in feasibility studies of river engineering and irrigation-related projects under arid and semi-arid condition. Flood control is one of the crucial factor, the management of which while mitigates its destructive consequences, abstracts considerable volume of renewable water resources. The methodology applied here was based on Mizumura, which applied a mathematical model for simple tank to simulate the rainfall-run-off process in a particular water basin using the data from the observational hydrograph. The model was applied in the Dez River water basin adjacent to Greater Dezful region, Iran in order to simulate and estimate the floods. Results indicated that the calculated hydrographs using the simple tank method, SCS-CN model and the observation hydrographs had a close proximity. It was also found that on average the flood time and discharge peaks in the simple tank were closer to the observational data than the CN method. On the other hand, the calculated flood volume in the CN model was significantly closer to the observational data than the simple tank model.